A meeting of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances (NAC/AEGL Committee) was held on July 26-28, 2000, in Washington, DC. At this meeting, the NAC/AEGL Committee addressed various aspects of the acute toxicity and the development of Acute Exposure Guideline Levels (AEGLs) for the following chemicals: Acetonecyanohydrin; acrolein; acrylic acid; Agent GA (tabun): ethyl N,N-dimethylphosphoramidocyanidate; Agent GB (sarin): O-isopropyl methylphosphonofluoridate; Agent GD (soman): O-pinacolyl methylphosphonofluoridate; Agent GF: O-cyclohexyl- methylfluorophosphonate; Agent VX: O-ethyl S-(2-diisopropylaminoethyl) methyl-phosphonothiolate; allyl alcohol; boron trichloride; chlorine trifluoride; diborane; epichlorohydrin; ethyleneimine; ethylene oxide; furan; hydrogen cyanide; hydrogen fluoride; iso-butyronitrile; methacrylonitrile; methanol; peracetic acid; perchloromethyl mercaptan; phosgene; propionitrile; propyleneimine; propylene oxide; tetrachloroethylene; uranium hexafluoride; and xylene.

There was a discussion of public comments as applicable and the setting of interim AEGL values for the following chemicals: Allylamine; cis- and trans-crotonaldehyde; cyclohexylamine; dimethyldichlorosilane; ethylenediamine; hydrogen chloride; iron pentacarbonyl; methyl isocyanate; methyltrichlorosilane; nickel carbonyl; phosphine; and 2,4- and 2,6-toluene diisocyanate. There was a discussion regarding any further National Academy of Sciences/National Research Council/ Committee on Toxicology/AEGL Subcommittee comments on the NAC/AEGL Committee Standing Operating Procedures.

• July26-28, 2000 (PDF)(236 pp, 8 MB)