An official website of the United States government.

This is not the current EPA website. To navigate to the current EPA website, please go to This website is historical material reflecting the EPA website as it existed on January 19, 2021. This website is no longer updated and links to external websites and some internal pages may not work. More information »

Assessing and Managing Chemicals under TSCA

Risk Evaluation for 1,3-Butadiene

EPA designated 1,3-butadiene as a high priority chemical in December 2019 and the chemical is currently undergoing risk evaluation.

Find other information about other chemicals undergoing risk evaluations under TSCA

On this page:

Background on 1,3-Butadiene

1,3-Butadiene (CASRN 106-99-0) is a colorless gas with a mild odor similar to gasoline, and it is highly flammable. The primary use of 1,3-butadiene is in the manufacturing of plastic and rubber products. Information from the 2016 Chemical Data Reporting (CDR) for 1,3-butadiene indicates the reported production volume is between 1 and 5 billion lbs/year (manufacture and import).

Uses of 1,3-Butadiene

In the final scope, EPA identified conditions of use associated with the manufacturing (including importing); processing; distribution in commerce; industrial, commercial and consumer uses; and disposal of 1,3-butadiene, for example:

  • As an intermediate in the manufacturing of adhesive, synthetic rubber, organic fiber, plastic material and resin, paints and coatings, and other chemical product and preparation manufacturing;
  • As an intermediate in the manufacturing of petroleum, petrochemical, and solid rocket fuels;
  • In adhesives and sealants;
  • In fuels and related products;
  • As a laboratory chemical;
  • In hydraulic fracturing fluids;
  • In automotive care products;
  • In lubricants and lubricant additives;
  • In paints and coatings; and
  • In plastic and rubber products (including rubber tires).

The above listed conditions of use are ways that a person or the environment could be potentially exposed to this chemical. However, when conducting a risk evaluation, EPA also considers the hazards (i.e. health effects or environmental impacts) that could occur from coming in contact with a chemical.

Recent Activities and Opportunities for Public Comment

In August 2020, EPA published a final scope document outlining the hazards, exposures, conditions of use, and the potentially exposed or susceptible subpopulations the agency expects to consider in its risk evaluation. The agency released the draft scope in April 2020 and took public comments on the draft document.

As EPA continues to move through the risk evaluation process there will be additional opportunities for public comment, including a public comment period on the draft risk evaluation. In addition to public comment periods, EPA will continue to engage with stakeholders as it refines the risk evaluation and stakeholders should reach out to EPA via the staff contact to engage with EPA.