The ten Berge model documentation provides an overview of the beta 1.0 implementation of a concentration by time (CxT) model. From the linked page, you can also download the peer-review comments on the model following its conversion to a format suitable for including in BMDS.

This model is no longer supported by EPA, but can be run from the archival BMDS 2.7.

• 2008 External Review of the Concentration x Time (ten Berge) Model
• Model Code Versions table
• Benchmark Dose Software (BMDS) Training Webinars: Time Models
• BMDS Quick Start Guide tutorial: ten Berge Concentration x Time Model (Use with Benchmark Dose Software (BMDS))