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Topic: SeqAPASS version 5.0: An emphasis on rapid data synthesis and interpretation

Who: Dr. Carlie LaLone, Bioinformaticist, Center for Computational Toxicology and Exposure (CCTE)

When: December 3, 2020 from 11:00 AM- 12:00 PM EST

Where: Register for webinar using EventbriteEXIT and check the confirmation email for webinar information.

Topic overview:

Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS), is a fast, online screening tool that allows researchers and regulators to extrapolate toxicity information across species. For some species, such as humans, mice, rats, and zebrafish, the EPA has a large amount of data regarding their toxicological susceptibility to various chemicals. SeqAPASS extrapolates from these data rich model organisms to thousands of other non-target species to evaluate their specific potential chemical susceptibility.

SeqAPASS Version 5.0 adds several new features including a customizable heat map for individual amino acid comparisons that allows for more rapid interpretation and use of the data for publication and presentation quality graphics. The new update also allows users to synthesize SeqAPASS results (i.e., data tables and visualizations) across all Levels (1, 2, and 3) of the SeqAPASS evaluation using a customizable Decision Summary Report. This report can be exported as a pdf.

This abstract does not necessarily reflect U.S. EPA policy.

For more information visit the EPA's Computational Toxicology Communities of Practice webpage