Tools and Databases to Support Children’s Health Protective Decisions
EPA researchers have released or are developing a suite of decision support tools to help public health officials, state, tribal, and local governments, and others make sound decisions that advance healthy, prosperous, and sustainable communities. Many of these tools can be used to ensure that children’s environmental health is an explicit part of such decision-making. These include the following:
| Name and Type | Acronym | Description |
|---|---|---|
| Consolidated Human Activity Database | CHAD | Compiled, detailed data on human behavior from 19 separate studies |
| Exposure Forecaster Database | ExpoCast | Automated model to predict exposures for thousands of chemicals |
| Aggregated Computational Toxicology Resource | ACToR | Data warehouse of all publicly available chemical toxicity data, including chemical structure, physico- chemical values, in vitro assay data and in vivo toxicology data. |
| Physiological Parameters Database for PBPK Modeling | - | Includes physiological parameters such as alveolar ventilation, blood flow, tissue volumes, and glomerular filtration rate used for Physiologically- Based Pharmacokinetic (PBPK) modeling |
| Chemical and Product Categories Database | CPCat | Database containing information on the uses of chemicals, products that contain chemicals and manufacturers of the products |
| Ontogeny Database on Enzymes | - | Database that can be used as a screening tool to explore metabolism-based variability, based on enzyme differences, during early lifestages |
| Toxicity Forecaster Database | ToxCast | Builds computational models from HTS data to forecast the potential human toxicity of chemicals |
| Toxicity Reference Database | ToxRef | Captures thousands of in vivo animal toxicity studies on hundreds of chemicals |
| Adverse Outcome Pathway Wiki | AOP Wiki | Provides an open-source interface for rapid and collaborative sharing of established AOPs and building new AOPs |
| Virtual Tissues Knowledgebase | VT-KB | A human and machine readable knowledgebase developed by extracting and organizing relevant facts from the scientific literature and other sources of information in to central database |
| Exposure Toolbox | Expo-Box | Web-based compendium of over 800 exposure assessment tools that provides links to exposure assessment databases, models, and references |
| Exposure Factors Handbook | EFH | Summary of the available statistical data on various factors used in assessing human exposure |
| Stochastic Human Exposure and Dose Simulations– HT Model | SHEDS-HT | A probabilistic human exposure model that produces population-level distributions of exposures by the dermal, inhalation, and ingestion routes |
| Stochastic Human Exposure and Dose Simulation Model for Multimedia | SHEDS-Multimedia | A physically-based, probabilistic model, that can simulate multiple- or single-chemical exposures over time for a population via residential and dietary exposure routes for a variety of multimedia, multipathway environmental chemicals |
| Community-Focused Exposure and Risk Screening Tool | C-FERST | A community mapping, information access, and assessment tool designed to help assess risk and assist in decision making with communities |
| EnviroAtlas | - | Collection of tools and resources that provides geospatial data, maps, research, and analysis on the relationships between nature, people, health, and the economy |
| Eco-Health Relationship Browser | - | Interactive tool that illustrates scientific evidence for linkages between human health and ecosystem services |
| Environmental Quality Index | EQI | Estimates environmental quality at the county level used to assess effects on health outcomes |
| CompTox Dashboard | - | Provides access to data associated with over 700,000 chemicals. Features mapping of curated physiocochemical property data associated with chemical substances to their corresponding chemical structures |