An official website of the United States government.

This is not the current EPA website. To navigate to the current EPA website, please go to This website is historical material reflecting the EPA website as it existed on January 19, 2021. This website is no longer updated and links to external websites and some internal pages may not work. More information »


Good Laboratory Practices - Standard Operating Procedures

Standard operating procedures (SOPs) are developed by EPA as guidance for inspectors done under the Good Laboratory Practices (GLPs) program as set forth in the Federal Insecticide, Rodenticide and Fungicide Act and the Toxic Substances Control Act. The SOPs only are directive in nature for EPA. Testing facilities may use the SOPs as guidance in complying with the GLPs. The SOPs below provide facilities and organizations with an appreciation of EPA's objectives and the procedures employed during a GLP inspection.

You may need a PDF reader to view some of the files on this page. See EPA’s About PDF page to learn more.