An official website of the United States government.

This is not the current EPA website. To navigate to the current EPA website, please go to www.epa.gov. This website is historical material reflecting the EPA website as it existed on January 19, 2021. This website is no longer updated and links to external websites and some internal pages may not work. More information »

Current and Previously Registered Section 3 Plant-Incorporated Protectant (PIP) Registrations

Revised 7/14/2020

You may need a PDF reader to view some of the files on this page. See EPA’s About PDF page to learn more.

PIP Active Ingredients Registered 1995 – 2020
Active
Ingredient
Commodity Year
Registered
Status Link To BRAD or other Regulatory Documents1
Cry14Ab-1 and the Genetic Material Necessary for its production (vector pSZ8832)
(PC Code: 006609)
Soybean 2020 Active Registration Decision for the New Active Ingredient Cry14Ab-1 and the Genetic Material Necessary for its Production (vector pSZ8832) in GMB151 Plant-Parasitic Nematode-Protected Soybean (OECD Unique Identifier: BCS-GM151-6)
Cry51Aa2.834_16 in MON 88702
(PC Code: 006999)
Cotton 2018 Active Registration Decision for the New Active Ingredient Bacillus thuringiensis Cry51Aa2.834_16 and the Genetic Material (vector PV-GHIR508523) Necessary for its Production in MON 88702 Cotton (OECD Unique Identifier: MON-88702-4
VNT1 in potato
(PC code: 006355)
Potato 2017 Active Final Registration Decision for the New Active Ingredient and Food Use of VNT1 Protein and the Genetic Material Necessary for its Production in Potatoes
Cry1Ab in event 176
(PC code: 006458)
Corn 1995 Canceled
(2003)
Biopesticides Registration Action Document - Bacillus thuringiensis Plant-Incorporated Protectants
Cry1Ab in event MON 810 (PDF)
(PC code: 006526)
Corn 1996 Active Cry1Ab and Cry1F Bacillus thuringiensis (Bt) (PDF)(253 pp, 1.3 MB, About PDF)
Cry1Ab in event MON 801
(PC code: 006408)
Corn 1996 Canceled
(1998)
Biopesticides Registration Action Document - Bacillus thuringiensis Plant-Incorporated Protectants
Cry1Ab in event Bt11 (PDF)
(PC code: 006461)
Corn 1996 Active Bacillus thuringiensis (Bt) (PDF)(253 pp, 1.3 MB, About PDF)
Cry1Ac in event DBT 418
(PC code: 006463)
Corn 1997 Canceled
(2000)
Bacillus thuringiensis kurstaki Decision Document (PDF)(22 pp, 1.7 MB, About PDF)
Cry9C in event CBH 351
(PC code: 006466)
Corn 1998 Canceled (2001) Starlink™ Corn Regulatory Information
Cry1F in event TC1507
(PC code: 006481)
Corn 2001 Active Cry1Ab and Cry1F Bacillus thuringiensis (Bt) Corn Plant-Incorporated Protectant (PDF)(253 pp, 1.3 MB, About PDF)
Cry3Bb1 in event MON 863
(PC code: 006484)
Corn 2003 Canceled
(2010)
Bacillus thuringiensis Cry3Bb1 Protein and the Genetic Material Necessary for Its Production (Vector PV-ZMIR13L) in MON 863 Corn (PDF)(234 pp, 978 K, About PDF)
moCry1F in event DAS-06275-8
(PC code: 006491)
Corn 2005 Active Cry1Ab and Cry1F Bacillus thuringiensis (Bt) Corn Plant-Incorporated Protectants (PDF)(253 pp, 1.3 MB, About PDF)
Cry34/35 in event 59122-7
(PC code: 006490)
Corn 2005 Active Bacillus thuringiensis Cry34Ab1 and Cry35Ab1 Proteins and the Genetic Material Necessary for Their Production (PHP17662 T-DNA) in Event DAS-59122-7 Corn (OECD Unique Identifier: DAS-59122-7) (PDF)(205 pp, 1.2 MB, About PDF)
Cry3Bb1 in event MON 88017
(PC code: 006498)
Corn 2005 Active Bacillus thuringiensis Cry3Bb1 Protein and the Genetic Material Necessary for Its Production (Vector
PV-ZMIR39) in MON 88017 Corn (OECD Unique Identifier: MON-88Ø17-3) (PDF)
(234 pp, 978 K, About PDF)
mCry3A in Event MIR 604
(PC code: 006509)
Corn 2006 Active Modified Cry3A Protein and the Genetic Material Necessary for its Production (Via Elements of pZM26) in Event MIR604 Corn SYN-IR604-8 (PDF)(141 pp, 578 K, About PDF)
Cry1A.105 in event MON 89034
(PC code: 006514)
Corn 2008 Active Bacillus thuringiensis Cry1A.105 and Cry2Ab2 Insecticidal Proteins and the Genetic Material Necessary for Their Production in Corn [PC Codes 006515 (Cry2Ab2), 006514 (Cry1A.105)] (PDF)(166 pp, 826 K, About PDF)
Cry2Bb2 in event MON 89034
(PC code: 006515)
Corn 2008 Active Bacillus thuringiensis Cry1A.105 and Cry2Ab2 Insecticidal Proteins and the Genetic Material Necessary for Their Production in Corn [PC Codes 006515 (Cry2Ab2), 006514 (Cry1A.105)] (PDF)(166 pp, 826 K, About PDF)
Vip3Aa20 in event MIR 162
(PC code: 006599)
Corn 2008 Active Bacillus thuringiensis Vip3Aa20 Insecticidal Protein and the Genetic Material Necessary for Its Production (via Elements of Vector pNOV1300) in Event MIR162 Maize (OECD Unique Identifier: SYN-IR162-4) (PDF)(175 pp, 784 K, About PDF)
eCry3.1Ab in event 5307
(PC code: 016483)
Corn 2012 Active Draft Biopesticides Registration Action Document Bacillus thuringiensis eCry3.1Ab Insecticidal Protein and Genetic Material
Cry3Bb1 in event MON 87411
(PC code: 006580)
Corn 2015 Active Registration Decision for the New Active Ingredients Double-stranded Ribonucleic Acid Transcript Comprising a DvSnj7 Inverted Repeat Sequence Derived from Western Corn Rootworm (Diabrotica virgifera virgifera) and Bacillus thuringiensis Cry3Bbl Protein and the Genetic Material (vector PV-ZMIR10871) Necessary for Their Production in MON 87411 Corn (OECD Unique Identifier: MON-87411-9) 
DvSnf7 in event MON 87411
(PC code: 006566)
Corn 2015 Active Registration Decision for Commercial Use Corn Products Containing the DvSnf7 dsRNA Plant-Incorporated - Protectant (Event MON 87411)
Cry1Ac in event MON 531
(PC code: 006445
Cotton 1995 Active

Biopesticides Registration Action Document - Bacillus thuringiensis Plant-Incorporated Protectants

Cry1Ac in event MON 15985
(PC code:  006445)
Cotton 2002 Active Bacillus thuringiensis Cry2Ab2 protein and its genetic material necessary for its production in cotton(75 pp, 775 K, About PDF)
Cry2Ab2 in event MON 15985
(PC code 006487)
Cotton 2002 Active Bacillus thuringiensis Cry2Ab2 protein and its genetic material necessary for its production in cotton(75 pp, 775 K, About PDF)
Cry1F in event DAS-21023-5
(PC code:  006512)
Cotton 2004 Active (Bacillus thuringiensis var. Aizawai CRY1F and the Genetic Material (from the insert of Plasmid PGMA281) Necessary for Its Production in Cotton and Bacillus thuringiensis var. Kurstaki CRY1AC and the Genetic Material (from the insert of plasmid PMYC3006) necessary for its production in cotton)(93 pp, 571 K, About PDF)
Cry1Ac in event DAS-24236-5
(PC code:  006513)
Cotton 2004 Active (Bacillus thuringiensis var. Aizawai CRY1F and the Genetic Material (from the insert of Plasmid PGMA281) Necessary for Its Production in Cotton and Bacillus thuringiensis var. Kurstaki CRY1AC and the Genetic Material (from the insert of plasmid PMYC3006) necessary for its production in cotton)(93 pp, 571 K, About PDF)
Vip3Aa19 in event COT102
(PC code:  016484)
Cotton 2008 Active Bacillus thuringiensis modified Cry1Ab (SYN-IR67B-1) and Vip3Aa19 (SYN-IR102-7) insecticidal proteins and the genetic material necessary for their production in COT102 X COT67B cotton(135 pp, 2.2 MB, About PDF)
FLCry1Ab in event COT67B
(PC code:  016486)
Cotton 2008 Active Bacillus thuringiensis modified Cry1Ab (SYN-IR67B-1) and Vip3Aa19 (SYN-IR102-7) insecticidal proteins and the genetic material necessary for their production in COT102 X COT67B cotton(135 pp, 2.2 MB, About PDF)
Cry1Ab in event T304-40
(PC code:  006525)
Cotton 2012 Active Bacillus thuringiensis Cry1Ab protein and the Genetic Material Necessary for its Production in Event T304-40 Cotton [PC Code 006525, OECD Unique Identifier: BCS-GHØØ4-7]
Cry2Ae in event GHB119
(PC code:  006600)
Cotton 2012 Active Bacillus thuringiensis Cry2Ae protein and the Genetic Material Necessary for its Production in Event GHB119 Cotton [PC Code 006600, OECD Unique Identifier: BCS-GHØØ5-8]
Cry1Ac in event MON 87701
(PC code: 006532)
Soybean 2010 Active Bacillus thuringiensis Cry1Ac Protein and the Genetic Material (Vector PV-GMIR9) Necessary
for Its Production in MON 87701 (OECD Unique Identifier: MON 877Ø1-2) Soybean (PDF)
(39 197, yy K, About PDF)
Cry1Ac in event DAS 81419 (PC code: 006527) Soybean 2014 Active Bacillus thuringiensis Cry1Ac Protein and the Genetic Material Necessary for its Production [PC Code 006527] and Bacillus thuringiensis Cry1F Protein and the Genetic Material Necessary for its Production [PC Code 006528]
Cry1F in event DAS 81419 (PC code: 006528) Soybean 2014 Active Bacillus thuringiensis Cry1Ac Protein and the Genetic Material Necessary for its Production [PC Code 006527] and Bacillus thuringiensis Cry1F Protein and the Genetic Material Necessary for its Production [PC Code 006528]
Cry1A.105 in event MON 87751
(PC code: 006614
Soybean 2015 Active Plant-Incorporated Protectants Bacillus Thuringiensis Cry1A.105 and Cry2Ab2 Proteins and the Genetic Material (Vector PV-GMIR13196) Necessary For Their Production in MON 87751 (OECD Unique ID. MON-87751-7) Soybean [PC Code 006614 and PC Code 006527]
Cry2Ab2 in event MON 87751
(PC code: 006615)
Soybean 2015 Active Plant-Incorporated Protectants Bacillus Thuringiensis Cry1A.105 and Cry2Ab2 Proteins and the Genetic Material (Vector PV-GMIR13196) Necessary For Their Production in MON 87751 (OECD Unique ID. MON-87751-7) Soybean [PC Code 006614 and PC Code 006527]
Cry3A in New Leaf Potato
(PC code: 006432)
Potato 1995 Active Biopesticides Registration Action DocumentBacillus thuringiensis Plant-Incorporated Protectants
Replicase for potato leaf roll virus
(PC code: 006469
Potato 1998 Active Potato Leaf Roll Virus Resistance Gene (also known as orf1/orf2 gene) (006469) Registration Eligibility Document (PDF)(19 pp, 71 K, About PDF)
C5 Honeysweet plum (plum pox viral coat protein gene)
(PC code: 006354)
Plum 2010 Active Coat Protein Gene of Plum Pox Virus (PDF)(30 pp, 288 K, About PDF)
X17-2 papaya (ringspot virus resistance gene)
(PC code: 006701)
Papaya 2016 Active Proposed Registration Decision for the New Active Ingredient Papaya Ringspot Virus Resistance Gene (Papaya Ringspot Virus Coat Protein Gene) in Xl7-2 Papaya (OECD Unique Identifier: UFL-Xl7CP-6)

1BRAD = Biopesticide Registration Action Document, a summary of the risk assessments and regulatory decisions for each registered PIP active ingredient

Counts:

Total Active PIP Active Ingredients: 34

  • Corn: 13
  • Cotton: 10
  • Soybean: 6
  • Potato: 3
  • Other: 2

Total Canceled PIP Active Ingredients:  5 (Corn: 5)

Top of Page