An official website of the United States government.

This is not the current EPA website. To navigate to the current EPA website, please go to This website is historical material reflecting the EPA website as it existed on January 19, 2021. This website is no longer updated and links to external websites and some internal pages may not work. More information »

R125 PRIA Fee Category

PRIA 4 Fee Determination Decision Tree:

Conventional Active Ingredient - Experimental Use Permit Request

Below is the fee for your selected Fee Category for Fiscal Years 2020-2021

Action Code Description FY'20-FY'21 Fee Decision Time (months)
R125 New Active Ingredient, Seed treatment; Experimental Use Permit application, submitted before application for registration; credit 45% of fee toward new active ingredient application that follows (3) $339,875 16

Do you plan to request either of the following types of waivers?

Waiver Pay Amount
50% waiver You pay ---->>>>> $169,938
75% waiver You pay ---->>>>> $84,969

To pay the fee shown above, go to Paying PRIA Application Fees web page and follow the instructions.

How to submit your application directly to EPA.

Action Code Interpretation

An Experimental Use Permit (EUP) application for seed treatment only that proposes a use for an active ingredient that is not currently contained as an active ingredient in any U.S. registered pesticide product that is not expected to result in residues in raw agricultural commodities. All uses included in the original application for a new active ingredient are covered by the base fee for the application in this category.  In order for a food crop seed treatment to be considered in this category, data from a radiotracer study must be available showing no uptake of residues (radioactivity) from treated seed into the aerial portion of the growing crop.  Guidance is available at ( If residues occur in the aerial portion of the plant, or if there is no data available to make this determination, seed treatments are considered to be food uses requiring tolerances and fall into a different category.  45% of this category’s fee will be credited against the new active ingredient’s application fee whose submission follows that of this EUP application.

All of the inerts used in the product must be either approved or pending with the Agency for the applicable uses.

The Agency will provide the applicant with a pre-decisional determination 4 weeks prior to the PRIA decision review time due date which specifies any label changes that have to be made in order to grant the requested experimental use permit.  If the label issues cannot be resolved prior to the PRIA decision review time due date and if a PRIA due date time extension has not been agreed upon, then the Agency will issue to the applicant its regulatory decision with the specific label changes and supporting documentation on or just before the PRIA decision review time due date.  At that time the applicant must either (a) agree to all of the label changes and submit a revised label that incorporates all of these label changes; or (b) does not agree with one or more of the label changes and request up to 30 days to reach agreement with the Agency and submit a revised label that incorporates all of the agreed upon label changes, which the Agency has 2 business days to review; or (c) withdraw the application without prejudice.

Go to the start of the Decision Tree