A petition to amend six or more existing tolerances on domestic or imported crops and for which there is not a related label amendment request necessitating the proposed tolerance amendments. This may be a request to increase or decrease existing tolerances currently established under section 408 of the FFDCA. This category is applicable when tolerance amendments are being requested but no related label amendment is necessary or being requested. For purposes of counting, all tolerance amendments within a commodity (e.g., tomato) are counted as one use. If amendment to a crop group or subgroup tolerance is requested, the fee is based on the number of representative crops in that group or subgroup.  Examples of situations to which this category might apply include but are not limited to requests to increase 6 or more existing tolerances to reflect residue data demonstrating higher observed residues than the existing tolerances or requests to move 6 or more existing tolerances from one paragraph to another within the citation in 40 CFR Part180. Examples of food uses include: use on foods, for example, corn or apples; aquatic uses involving potable water, irrigation, or requiring tolerances for fish, or shellfish; uses on areas where food may be grown or raised such as pasture, rangeland, home garden, beehive, and uses involving livestock, such as livestock housing, livestock dips, and  livestock ear tags.

If a tolerance amendment petition also requests the establishment of a tolerance in association with the raw agricultural commodity (RAC) (e.g., a processed form of the RAC for which a tolerance was not previously established), this tolerance establishment activity falls under R170.