We have reviewed the referenced protocol for a laboratory test of mosquito repellent-impregnated clothing for the United States Military from both scientific and ethics perspectives. This review assesses the scientific aspects of the proposed research for a special efficacy study to assess etofenprox-treated U.S. Military uniforms in terms of the recommendations of the EPA and of the EPA Human Studies Review Board. Ethical aspects of the proposed research are assessed in terms of the standards defined by 40 CFR 26 subparts K and L and the recommendations of the EPA Human Studies Review Board.