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EPA Research

Milestones in EPA's Ecosystem Health Research History

EPA turns 50 this year. Since the beginning, our Agency has been grounded in science. Ecosystem-focused research develops methods that measure ecosystem goods and services. Ecosystem goods and services produce the many life-sustaining benefits we receive from nature—clean air and water, fertile soil for crop production, pollination, and flood control. These ecosystem services are important to environmental and human health and well-being. Here are some of our most important research achievements over the last 50 years. 
See also:
History of EPA Research
EPA at 50: Progress for a Stronger Future

1974 - EPA Conducts Research on the Pesticide Mirex

AntEPA conducts critical research on the pesticide, Mirex, which was being applied throughout the Southeast to combat fire ants. Results with aquatic organisms indicated significant adverse effects to crustaceans and bioaccumulation in higher predatory species ultimately contributing to EPA’s ban of this pesticide.

EPA's Safer Chemicals Research

1989 - EPA Initiates the Environmental Monitoring and Assessment Program

LakeEPA initiates and leads the Environmental Monitoring and Assessment Program, documenting for the first time the status and trends of the nation’s ecological resources. The first stream survey using common indicators and design was completed in 1994. In 2000, a pilot program was implemented to monitor and assess water quality in streams and rivers in the western U.S. using common ecological indicators and survey design.

The Environmental Monitoring and Assessment Program (EMAP)

1991 - EPA Begins the Northeast Lake Survey

LakeEPA begins the Northeast Lake Survey to assess regional patterns of lake-trophic conditions in the northeastern United States using a probability sampling design. This approach permitted investigators to sample only a small fraction of the total lake population, while inferring the sample conditions to lakes throughout the Northeast.

EPA Science Matters Newsletter: Climate Change and Watersheds: Exploring the Links
EPA's Watershed Research 

1998 - EPA Publishes Guidelines for Ecological Risk Assessment

TreeEPA published the Guidelines for Ecological Risk Assessment that outline the ecological risk assessment process including problem formulation, analysis, and risk characterization. The work improved risk assessments by EPA and informed the public and the regulated community on the Agency’s approach to ecological risk assessment.

EPA's Guidelines for Ecological Risk Assessment

2000 - EPA Releases a Web-based ECOTOX Database

EcotoxEPA releases a web-based version of the ECOTOX database that contains information on the toxic effects of chemicals on aquatic animals, plants, and wildlife. In 2018, EPA released an updated version, which provides researchers, risk assessors and decision makers access to nearly a million records of environmental toxicity data for approximately 12,000 chemicals and 13,000 species. EPA uses the data to evaluate substances and develop aquatic life ambient water quality criteria for toxics.

ECOTOX 5.0 Improves Access to Chemical Information on Ecological Species
ECOTOX Knowledgebase

2000 - EPA Completes the First Year of the Coastal 2000 Monitoring Effort

Coastal AssessmentEPA completes the first year of the Coastal 2000 monitoring effort conducted in conjunction with coastal states. This five-year effort led by the Office of Research and Development surveyed the condition of the national’s coastal resources using a common set of ecological indicators and assessment methods and working in partnership with all 24 coastal states and Puerto Rico.

Coastal Communications: National Coastal Assessment--Coastal 2000

2000 - EPA Studies the Impacts of Hypoxia on the Gulf of Mexico

Gulf of MexicoEPA assists the Gulf of Mexico Alliance to characterize Gulf hypoxia (low oxygen levels) and its impacts on the Gulf of Mexico. In 2002, researchers initiated Gulf of Mexico monitoring with the first of 13 hypoxia surveys, which led to the development of a hypoxia model for the Gulf. In 2018, EPA developed and applied tools to quantify the hydrodynamic and biogeochemical processes controlling oxygen dynamics in the Gulf of Mexico for development and implementation of effective strategies to reduce Gulf of Mexico hypoxia.

Mississippi River/Gulf of Mexico Hypoxia Task Force

2001 -EPA Co-Authors the First National Climate Assessment

IcebergEPA co-authors the first National Climate Assessment, which was coordinated by the United States Global Change Research Program. The report provides a comprehensive assessment on climate change impacts in the United States. EPA co-authored subsequent National Climate Assessments in 2009, 2013, and 2018.

2003 - EPA Begins Work on the Report on the Environment

Hands Holding PlantEPA began a bold initiative to assemble, for the first time, the most reliable available indicators of national environmental and health conditions and trends that are important to EPA’s mission. The Agency released the Report on the Environment and a companion report in 2008. EPA continues to update the report that provides the best available indicators of national trends in the status and condition of the U.S. environment and human exposure and health.

EPA's Report on the Environment (ROE)

2006 - EPA Studies the State of the Great Rivers

RiverEPA conducts the first ever ecological condition assessment of the Great Rivers of the Mississippi River basin with state partners, the Ohio River Valley Sanitation Commission, and the US Geological Survey.

EPA Collaborates with State and Federal Partners to Study the State of the Great Rivers

2011 - EPA Publishes an Assessment of Appalachian Coalfields

Coalfields Report CoverEPA publishes an assessment, which informs guidance and regulatory activities taken by EPA to protect waters in Appalachia.

The Effects of Mountaintop Mines and Valley Fills on Aquatic Ecosystems of the Central Appalachian Coalfields


2012 - EPA Releases the Eco-Health Relationship Browser

Relationshionship BrowserEPA releases the Eco-Health Relationship Browser to help communities and others better account for and protect the benefits they derive from natural ecosystems. The browser is designed to increase understanding of the nation’s ecosystems, the services they provide, and how those services benefit public health and well-being.

EnviroAtlas Eco-Health Relationship Browser

2014 - EPA Releases EnviroAtlas

EnviroAtlas Graphic IdentifierEPA releases EnviroAtlas, a GIS-based resource that provides geospatial data, easy-to-use tools, and other resources related to ecosystem services, their stressors, and human health. This free, robust resource is among the first tools to help environmental managers and others explore and visualize the connections between natural ecosystems and healthy, stainable communities.


2014 - EPA Reports on the Effects of Mining on Bristol Bay Fisheries

Bristol  Bay Report CoverEPA publishes a report to explain how future large-scale mining may affect water quality and the Bristol Bay salmon fisheries. Research has contributed to understanding of the environmental impacts on salmon populations.

An Assessment of Potential Mining Impacts on Salmon Ecosystems of Bristol Bay, Alaska


2015 - EPA Publishes the Water Connectivity Report

Waters Report CoverEPA publishes a report providing the technical basis for clean water rulemaking by the Agency. The report summarizes the current understanding about the connectivity and mechanisms by which streams and wetlands affect the physical, chemical and biological integrity of downstream waters.

Connectivity of Streams and Wetlands to Downstream Waters: A Review and Synthesis of the Scientific Evidence


2015 - EPA Demonstrates New Sampling for Detection of Invasive Species

Ship Releasing Ballast WaterEPA demonstrates sampling designs and associated technologies for the early detection of aquatic invasive species in the Great Lakes. The resulting detection network helps fulfill EPA’s obligation to provide the science to protect water quality under the Great Lakes Water Quality Agreement with Canada.

Detecting and monitoring aquatic invasive species

2015 - EPA Publishes Protocols for Assessing Sediment-Associated Contaminants

Sediments in WaterEPA publishes the first standardized protocols for assessing the toxicity of sediment-associated contaminants to benthic organisms. These methods are used extensively in EPA regulatory programs and National Pollutant Discharge Elimination System permitting as well as for pesticide registration and Superfund site assessments.

Tools and Methods for Contaminated Sediments Research

2016 - EPA Releases the SeqAPASS Screening Tool

HoneybeeEPA releases the fast, online screening tool, Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS), which can be used to consistently predict species susceptibility of chemical exposure. SeqAPASS has contributed to EPA’s support for the National Strategy to Promote the Health of Honey Bees and Other Pollinators. This tool is nationally and internationally recognized as a valuable cross-species toxicity estimation tool.

Sequence Alignment to Predict Across Species Susceptibility

2016 - EPA Publishes the National Wetland Condition Assessment Report

WetlandsEPA publishes the National Wetland Condition Assessment Report, providing the first ever national report on the quality of wetlands. This first baseline report, based on an assessment completed by EPA in 2011, will now allow changes in wetland condition to be tracked over time. The data allow wetlands to be compared with others in their regions, revealing local or widespread trends in condition. They also provide an opportunity to explore patterns in wetlands in their ecological differences at a continental scale.

What is the National Wetland Condition Assessment?

2016 - EPA Publishes the StreamCat Dataset

Mountain StreamEPA publishes the Stream-Catchment (StreamCat) dataset, which includes over 500 natural and anthropogenic watershed measurements representing 2.6 million streams in the conterminous U.S. The data are extrapolated from measurements made every five years under the National Rivers and Streams Assessment and help states identify streams potentially in need of restoration.

StreamCat Dataset
National Rivers and Streams Assessment

2018 - EPA Publishes the LakeCat Dataset

Duck on LakeEPA publishes the Lake-Catchment (LakeCat) dataset containing extrapolated measurements for 380,000 lakes in the conterminous U.S. The data are derived from measurements made every five years under the National Lakes Assessment and help states to identify lakes and reservoirs potentially in need of restoration.

LakeCat Dataset
National Lakes Assessment