The effectiveness of special techniques should be confirmed by acceptable performance of initial and on-going QC.

Special techniques discussed in this module which require QC validation are:
- Removing magnetic materials
- Adjusting the pH
- Incorporating flat-sided tube rinse or bead pellet wash
- Heat dissociation method
- Modification of sample application to slides
Initial QC:
- 4 reagent water organism-spiked samples and one method blank required.
- Matrix spike, matrix spike duplicate, and unspiked field sample analyses strongly recommended.
On-going QC:
- Process matrix spike sample(s) with the same modification as the associated field sample.
- Process the equivalent percentage of OPR samples and field samples using the same special technique.
See the Lab Guidance Manual for more information on Quality Control procedures.

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