Method 1622/1623
Immunomagnetic Separation
Removing Magnetic Materials
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Some source water samples can contain high concentrations of iron and other magnetic material. Low recoveries could occur if extraneous magnetic material is present to interfere with the IMS process.

Some laboratories have determined the removal of extraneous magnetic material from the pellet, prior to the addition of beads, can improve recoveries.

The sample is processed through filtration, elution, and concentration. Extraneous magnetic material is removed from the pellet and the supernatant is carried through the remainder of the process.

See the IMS Supplement for the protocol and required quality control.

Packed pellets, magnetic material being removed, supernatant being poured

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