Substitutes in Inks
You may need a PDF reader to view some of the files on this page. See EPA’s About PDF page to learn more.Substitutes are reviewed on the basis of environmental and health risks, including factors such as ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptableacceptableThis designation means that a substitute may be used, without restriction, to replace the relevant ODS within the end-use specified. For example, HCFC-22 is an acceptable substitute for R-502 in industrial process refrigeration. Note that all SNAP determinations apply to the use of a specific product as a substitute for a specific ODS in a specific end-use. and Unacceptable
UnacceptableThis designation means that it is illegal to use a product as a substitute for an ODS in a specific end-use. For example, HCFC-141b is an unacceptable substitute for CFC-11 in building chillers. Note that all SNAP determinations apply to the use of a specific product as a substitute for a specific ODS in a specific end-use. substitutes are updated several times each year. The list of substitutes is shown below.
Note: SNAP-related information published in the Federal Register takes precedence over all information on this page.
Substitute | Trade Name(s) | ODP![]() |
GWP![]() |
Flammable | SNAP Listing Date | Listing Status | Further Information |
---|---|---|---|---|---|---|---|
Alternative technologies (e.g., powder, hot melt, thermoplastic plasma spray, radiation-cured, moisture-cured, chemical-cured, and reactive liquid) | 0 | N/A | N/A | March 18, 1994 | Acceptable | ||
Benzotrifluoride | N/A | N/A | yes | June 8, 1999 | Acceptable with Use Conditions: Subject to a 100 ppm acceptable exposure limit (AEL). | ||
Chlorinated solvents (methylene chloride, trichloroethylene, perchloroethylene) | N/A | N/A | N/A | March 18, 1994 | Acceptable | High inherent toxicity. Use only when necessary. OSHA and RCRA standards must be met. | |
Chlorobromomethane | 0.07 to 0.15 | N/A | no | April 28, 1999 | Unacceptable | Alternatives exist with lower or zero ODP. | |
HCFC-141b and blends thereof | >0 | N/A | no | July 20, 2015 | Unacceptable as of September 18, 2015. | ||
HFE-449s1 (methoxynonafluorobutane, iso and normal) | Novec™ 7100 Engineered Fluid (HFE-7100) | 0 | 297 | no | March 22, 2002 | Acceptable | |
HFE-569sf2 (ethoxynonafluorobutane, iso and normal) | Novec™ 7200 Engineered Fluid (HFE-7200) | 0 | 59 | no | March 22, 2002 | Acceptable | |
High-solid formulations | 0 | N/A | N/A | March 18, 1994 | Acceptable | ||
Monochlorotoluene / Benzotrifluorides | N/A | N/A | N/A | May 22, 1996 | Acceptable with Use Conditions: Subject to a 50 ppm workplace standard for monochlorotoluenes and a 25 ppm standard for other benzotrifluorides (other than benzotrifluoride). | The workplace standard for monochlorotoluenes is based on an OSHA PEL of 50 ppm for orthochlorotoluene. The workplace standard for benzotrifluorides is based on a toxicology study. See separate listing for benzotrifluoride. | |
Oxygenated solvents (Alcohols, Ketones, Ethers, and Esters) | 0 | N/A | yes | March 18, 1994 | Acceptable | OSHA standards exist for many of these chemicals. Formulators should use chemicals with lowest toxicity, where possible. | |
Petroleum Hydrocarbons | 0 | N/A | yes | March 18, 1994 | Acceptable | OSHA standards exist for many of these chemicals. Formulators should use chemicals with lowest toxicity, where possible. | |
Terpenes | 0 | N/A | yes | March 18, 1994 | Acceptable | ||
Water-based formulations | 0 | N/A | no | March 18, 1994 | Acceptable |