An official website of the United States government.

This is not the current EPA website. To navigate to the current EPA website, please go to www.epa.gov. This website is historical material reflecting the EPA website as it existed on January 19, 2021. This website is no longer updated and links to external websites and some internal pages may not work. More information »

Single Laboratory Validated Method for Determination of Cylindrospermopsin and Anatoxin-a in Ambient Freshwaters by Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

This document is a standardized, single laboratory validated liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for the detection of cyanotoxins—cylindrospermopsin and anatoxin-a (combined intracellular and extracellular)—in ambient freshwater.

You may need a PDF reader to view some of the files on this page. See EPA’s About PDF page to learn more.

Method for Determination of Cylindrospermopsin and Anatoxin-a in Ambient Freshwaters (PDF)(29 pp, 356 K, 11/9/2017, EPA/600/R-17/130)