Health Effects Notebook for Hazardous Air Pollutants

Detailed information about the health effects of hazardous air pollutants (HAPs) is available in separate fact sheets, for nearly every HAP specified in the Clean Air Act Amendments of 1990. These substances include certain volatile organic chemicals, pesticides, herbicides, and radionuclides that present tangible hazard, based on scientific studies of exposure to humans and other mammals. There is uncertainty in the precise degree of hazard, and readers are cautioned that the fact sheets may be revised as additional data become available. The available fact sheets are listed below, alphabetically by chemical name, along with the Chemical Abstract Service Number (CAS No.), where available.

You may need a PDF reader to view some of the files on this page. See EPA’s About PDF page to learn more.

Acetaldehyde - CAS 75-07-0 (PDF)(4 pp, 62 K)
Acetamide - CAS 60-35-5 (PDF)(2 pp, 33 K)
Acetonitrile - CAS 75-05-8 (PDF)(4 pp, 60 K)
Acetophenone - CAS 98-86-2 (PDF)(4 pp, 69 K)
2-Acetylaminofluorene - CAS 53-96-3 (PDF)(2 pp, 34 K)
Acrolein - CAS 107-02-8 (PDF)(4 pp, 58 K)
Acrylamide - CAS 79-06-1 (PDF)(4 pp, 59 K)
Acrylic Acid - CAS 79-10-7 (PDF)(4 pp, 56 K)
Acrylonitrile - CAS 107-13-1 (PDF)(5 pp, 61 K)
Allylchloride - CAS 107-05-1 (PDF)(4 pp, 59 K)
4-Aminobiphenyl - CAS 92-67-1 (PDF)(2 pp, 35 K)
Aniline - CAS 62-53-3 (PDF)(4 pp, 76 K)
o-Anisidine (2-Methoyaniline) - CAS 90-04-0 (PDF)(4 pp, 49 K)
Antimony Compounds - CAS 7440-36-0 (PDF)(4 pp, 57 K)
Arsenic Compounds - CAS 107-02-8 (PDF)(6 pp, 175 K)
Asbestos - CAS 1332-21-4 (PDF)(5 pp, 138 K)
Benzene - CAS 71-43-2 (PDF)(5 pp, 61 K)
Benzidine - CAS 92-87-5 (PDF)(4 pp, 67 K)
Benzotrichloride - CAS 98-07-7 (PDF)(3 pp, 37 K)
Benzyl Chloride - CAS 100-44-7 (PDF)(4 pp, 55 K)
Beryllium Compounds - CAS 107-02-8 (PDF)(5 pp, 60 K)
Biphenyl - CAS 92-52-4 (PDF)(4 pp, 70 K)
Bromoform - CAS 75-25-2 (PDF)(5 pp, 56 K)
1,3-Butadiene - CAS 106-99-0 (PDF)(4 pp, 62 K)
Cadmium Compounds (PDF)(5 pp, 111 K)
Calcium Cyanamide - CAS 156-62-7 (PDF)(4 pp, 46 K)
Caprolactam - CAS 105-60-2 (PDF)(4 pp, 77 K)
Captan - CAS 133-06-2 (PDF)(4 pp, 72 K)
Carbaryl - CAS 63-25-2 (PDF)(4 pp, 49 K)
Carbon Disulfide - CAS 75-15-0 (PDF)(5 pp, 60 K)
Carbon Tetrachloride - CAS 56-23-5 (PDF)(5 pp, 83 K)
Carbonyl Sulfide - CAS 463-58-1 (PDF)(2 pp, 50 K)
Catechol (Pyrocatechol) - CAS 120-80-9 (PDF)(4 pp, 46 K)
Chloramben - CAS 133-90-4 (PDF)(4 pp, 51 K)
Chlordane - CAS 57-74-9 (PDF)(5 pp, 55 K)
Chlorine - CAS 7782-50-5 (PDF)(4 pp, 60 K)
Chloroacetic Acid - CAS 79-11-8 (PDF)(3 pp, 36 K)
2-Chloroacetophenone - CAS 532-27-4 (PDF)(4 pp, 53 K)
Chlorobenzene - CAS 108-90-7 (PDF)(4 pp, 55 K)
Chlorobenzilate - CAS 510-15-6 (PDF)(4 pp, 52 K)
Chloroform - CAS 67-66-3 (PDF)(5 pp, 89 K)
Chloromethyl Methyl Ether - CAS 107-30-2 (PDF)(4 pp, 83 K)
Bis(chloromethyl)ether (BCME) - CAS 542-88-1 (PDF)(4 pp, 78 K)
Chloroprene (2-Chloro-1,3-Butadiene) - CAS 126-99-8 (PDF)(6 pp, 164 K)
Chromium Compounds (PDF)(6 pp, 70 K)
Cobalt Compounds (PDF)(4 pp, 59 K)
Coke Oven Emissions (PDF)(4 pp, 53 K)
Cresol/Cresylic Acid - CAS 1319-77-3 (PDF)(4 pp, 55 K)
Cumene - CAS 98-82-8 (PDF)(4 pp, 76 K)
Cyanide Compounds - CAS 74-90-8 (PDF)(4 pp, 59 K)
DDE (1,1-Dichloro-2,2-bis(p-Chlorophenyl) Ethylene) - CAS 72-55-9 (PDF)(4 pp, 54 K)
Diazomethane - CAS 334-88-3 (PDF)(3 pp, 55 K)
Dibenzofuran - CAS 132-64-9 (PDF)(2 pp, 63 K)
1,2-Dibromo-3-Chloropropane (DBCP) - CAS 96-12-8 (PDF)(4 pp, 55 K)
Dibutyl Phthalate - CAS 84-74-2 (PDF)(4 pp, 56 K)
1,4-Dichlorobenzene (para- Dichlorobenzene) - CAS 106-46-7 (PDF)(4 pp, 55 K)
3,3'-Dichlorobenzidine - CAS 91-94-1 (PDF)(4 pp, 46 K)
Dichloroethyl Ether (BIS(2-Chloroethyl)Ether) - CAS 111-44-4 (PDF)(4 pp, 78 K)
1,3-Dichloropropene - CAS 542-75-6 (PDF)(5 pp, 58 K)
Dichlorvos - CAS 62-73-7 (PDF)(4 pp, 59 K)
Diethanolamine - CAS 111-42-2 (PDF)(4 pp, 48 K)
Diethyl Sulfate - CAS 64-67-5 (PDF)(4 pp, 46 K)
3,3-Dimethoxybenzidine - CAS 119-90-4 (PDF)(2 pp, 33 K)
Dimethyl Phthalate - CAS 131-11-3 (PDF)(3 pp, 46 K)
Dimethyl Sulfate - CAS 77-78-1 (PDF)(4 pp, 52 K)
4-Dimethylaminoazobenzene - CAS 60-11-7 (PDF)(2 pp, 32 K)
N,N-Dimethylaniline - CAS 121-69-7 (PDF)(4 pp, 146 K)
3,3'-Dimethylbenzidine - CAS 119-93-7 (PDF)(4 pp, 43 K)
Dimethylcarbamoyl Chloride - CAS 79-44-7 (PDF)(2 pp, 31 K)
N,N-Dimethylformamide - CAS 68-12-2 (PDF)(4 pp, 155 K)
1,1-Dimethylhydrazine - CAS 57-14-7 (PDF)(4 pp, 101 K)
4,6 Dinitro-o-Cresol (DNOC) (including salts) - CAS 534-52-1 (PDF)(4 pp, 83 K)
2,4-Dinitrophenol - CAS 51-28-5 (PDF)(4 pp, 73 K)
2,4-Dinitrotoluene - CAS 121-14-2 (PDF)(4 pp, 54 K)
1,4-Dioxane (1,4-Diethyleneoxide) - CAS 123-91-1 (PDF)(4 pp, 56 K)
1,2-Diphenylhydrazine - CAS 122-66-7 (PDF)(3 pp, 61 K)
Epichlorohydrin (1-Chloro-2,3- Epoxypropane) - CAS 106-89-8 (PDF)(5 pp, 60 K)
1,2-Epoxybutane - CAS 106-88-7 (PDF)(4 pp, 49 K)
Ethyl Acrylate - CAS 140-88-5 (PDF)(4 pp, 59 K)
Ethyl Carbamate (Urethane) - CAS 51-79-6 (PDF)(3 pp, 34 K)
Ethyl Chloride (Chloroethane) - CAS 75-00-3 (PDF)(4 pp, 56 K)
Ethylbenzene - CAS 100-41-4 (PDF)(4 pp, 55 K)
Ethylene Dibromide (Dibromoethane) - CAS 106-93-4 (PDF)(5 pp, 57 K)
Ethylene Dichloride (1,2-Dichloroethane) - CAS 107-06-2 (PDF)(5 pp, 58 K)
Ethylene Glycol - CAS 107-21-1 (PDF)(4 pp, 54 K)
Ethylene Oxide - CAS 75-21-8 (PDF)(4 pp, 328 K, 12/20/2018)
Ethylene Thiourea - CAS 96-45-7 (PDF)(4 pp, 54 K)
Ethyleneimine (Aziridine) - CAS 151-56-4 (PDF)(4 pp, 50 K)
Ethylidene Dichloride (1,1-Dichloroethane) - CAS 75-34-3 (PDF)(4 pp, 55 K)
Bis(2-ethylhexyl) phthalate (DEHP) - CAS 117-81-7 (PDF)(4 pp, 81 K)
Fine Mineral Fibers (PDF)(5 pp, 96 K)
Formaldehyde - CAS 50-00-0 (PDF)(5 pp, 95 K)
Glycol Ethers (PDF)(5 pp, 64 K)
Heptachlor - CAS 76-44-8 (PDF)(5 pp, 108 K)
Hexachlorobenzene - CAS 118-74-1 (PDF)(4 pp, 53 K)
Hexachlorobutadeine - CAS 87-68-3 (PDF)(4 pp, 81 K)
Hexachlorocyclopentadiene - CAS 77-47-4 (PDF)(4 pp, 75 K)
Hexachloroethane - CAS 67-72-1 (PDF)(5 pp, 60 K)
Hexamethylene Diisocyanate - CAS 822-06-0 (PDF)(4 pp, 54 K)
Hexamethylphosphoramide - CAS 680-31-9 (PDF)(2 pp, 33 K)
Hexane - CAS 110-54-3 (PDF)(4 pp, 54 K)
Hydrazine - CAS 302-01-2 (PDF)(4 pp, 58 K)
Hydrochloric Acid (Hydrogen Chloride) - CAS 7647-01-0 (PDF)(4 pp, 56 K)
Hydrogen Fluoride (Hydrofluoric Acid) - CAS 7664-39-3 (PDF)(6 pp, 154 K)
Hydroquinone - CAS 123-31-9 (PDF)(4 pp, 132 K)
Isophorone - CAS 78-59-1 (PDF)(4 pp, 58 K)
Lead Compounds (PDF)(4 pp, 155 K)
Lindane (Gamma-Hexachlorocyclohexane) - CAS 58-89-9 (PDF)(4 pp, 150 K)
Maleic Anhydride - CAS 108-31-6 (PDF)(4 pp, 138 K)
Manganese Compounds (PDF)(6 pp, 138 K)
Mercury Compounds (PDF)(7 pp, 182 K)
Methanol - CAS 67-56-1 (PDF)(4 pp, 55 K)
Methoxychlor - CAS 72-43-5 (PDF)(4 pp, 216 K)
Methyl Bromide (Bromomethane) - CAS 74-83-9 (PDF)(5 pp, 226 K)
Methyl Chloride (Chloromethane) - CAS 74-87-3 (PDF)(4 pp, 215 K)
Methyl Chloroform (1,1,1-Trichloroethane) - CAS 71-55-6 (PDF)(4 pp, 141 K)
Methyl tert-butyl Ether - CAS 1634-04-4 (PDF)(4 pp, 155 K)
Methyl Ethyl Ketone (2-Butanone) - CAS 78-93-3 (PDF)(4 pp, 183 K)
Methyl Iodide (Iodomethane) - CAS 74-88-4 (PDF)(4 pp, 160 K)
Methyl Isobutyl Ketone (Hexone) - CAS 108-10-1 (PDF)(4 pp, 197 K)
Methyl Isocyanate - CAS 624-83-9 (PDF)(4 pp, 157 K)
Methyl Methacrylate - CAS 80-62-6 (PDF)(5 pp, 203 K)
Methylene Chloride (Dichloromethane) - CAS 75-09-2 (PDF)(5 pp, 197 K)
4,4'-Methylenebis(2-Chlororaniline) (MBOCA) - CAS 101-14-4 (PDF)(4 pp, 48 K)
4,4'-Methylenedianiline (MDA) - CAS 101-77-9 (PDF)(4 pp, 75 K)
4,4'-Methylenediphenyl Diisocyanate (MDI) - CAS 101-68-8 (PDF)(4 pp, 53 K)
Methylhydrazine - CAS 60-34-4 (PDF)(4 pp, 129 K)
Naphthalene - CAS 91-20-3 (PDF)(5 pp, 159 K)
Nickel Compounds (PDF)(5 pp, 63 K)
Nitrobenzene - CAS 98-95-3 (PDF)(4 pp, 52 K)
4-Nitrobiphenyl - CAS 92-93-3 (PDF)(2 pp, 55 K)
4-Nitrophenol - CAS 100-02-7 (PDF)(3 pp, 46 K)
2-Nitropropane - CAS 79-46-9 (PDF)(4 pp, 55 K)
N-Nitroso- n-methylurea - CAS 684-93-5 (PDF)(2 pp, 89 K)
N-Nitrosodimethylamine - CAS 62-75-9 (PDF)(4 pp, 131 K)
N-Nitrosomorpholine - CAS 59-89-2 (PDF)(2 pp, 100 K)
Parathion - CAS 56-38-2 (PDF)(4 pp, 133 K)
Pentachloronitrobenzene (Quintozene) - CAS 82-68-8 (PDF)(4 pp, 51 K)
Pentachlorophenol - CAS 87-86-5 (PDF)(5 pp, 97 K)
Phenol - CAS 108-95-2 (PDF)(4 pp, 93 K)
p-Phenylenediamine - CAS 106-50-3 (PDF)(4 pp, 130 K)
Phosgene - CAS 75-44-5 (PDF)(4 pp, 93 K)
Phosphine - CAS 7803-51-2 (PDF)(4 pp, 165 K)
Phosphorus - CAS 7723-14-0 (PDF)(4 pp, 53 K)
Phthalic anhydride - CAS 85-44-9 (PDF)(4 pp, 77 K)
Polychlorinated Biphenyls (PCBs) (Arochlors) - CAS 1336-36-3 (PDF)(5 pp, 86 K)
Polycyclic Organic Matter (POM) (PDF)(5 pp, 54 K)
1,3-Propane Sultone - CAS 1120-71-4 (PDF)(2 pp, 32 K)
beta-Propiolactone - CAS 57-57-8 (PDF)(4 pp, 107 K)
Propionaldehyde - CAS 123-38-6 (PDF)(2 pp, 30 K)
Propoxur (Baygon) - CAS 114-26-1 (PDF)(4 pp, 73 K)
Propylene Dichloride (1,2-Dichloropropane) - CAS 78-87-5 (PDF)(4 pp, 54 K)
Propylene Oxide - CAS 75-56-9 (PDF)(5 pp, 132 K)
1,2-Propyleneimine (2-Methyl Aziridine) - CAS 75-55-8 (PDF)(4 pp, 47 K)
Quinoline - CAS 91-22-5 (PDF)(3 pp, 56 K)
Quinone (p-Benzoquinone) - CAS 106-51-4 (PDF)(4 pp, 70 K)
Radionuclides (including Radon, Radium and Uranium) (PDF)(5 pp, 147 K)
Selenium Compounds (PDF)(5 pp, 84 K)
Styrene - CAS 100-42-5 (PDF)(5 pp, 87 K)
Styrene Oxide - CAS 96-09-3 (PDF)(4 pp, 69 K)
2,3,7,8-Tetrachlorodibenzo-p-Dioxin (2,3,7,8,-TCDD) - CAS 1746-01-6 (PDF)(3 pp, 34 K)
1,1,2,2-Tetrachloroethane - CAS 79-34-5 (PDF)(5 pp, 56 K)
Tetrachloroethylene (Perchloroethylene) - CAS 127-18-4 (PDF)(5 pp, 181 K)
Titanium Tetrachloride - CAS 7550-45-0 (PDF)(4 pp, 92 K)
Toluene - CAS 108-88-3 (PDF)(5 pp, 166 K)
Toluene-2, 4-Diamine - CAS 95-80-7 (PDF)(3 pp, 95 K)
2,4-Toluene Diisocyanate - CAS 584-84-9 (PDF)(4 pp, 98 K)
o-Toluidine (2-Methylaniline) - CAS 95-53-4 (PDF)(4 pp, 132 K)
Toxaphene - CAS 8001-35-2 (PDF)(4 pp, 116 K)
1,2,4-Trichlorobenzene - CAS 120-82-1 (PDF)(4 pp, 49 K)
1,1,2-Trichloroethane - CAS 79-00-5 (PDF)(4 pp, 59 K)
Trichloroethylene - CAS 79-01-6 (PDF)(5 pp, 82 K)
2,4,5-Trichlorophenol - CAS 95-95-4 (PDF)(4 pp, 52 K)
2,4,6-Trichlorophenol - CAS 88-06-2 (PDF)(3 pp, 45 K)
Triethylamine - CAS 121-44-8 (PDF)(4 pp, 133 K)
Trifluralin - CAS 1582-09-8 (PDF)(4 pp, 54 K)
2,2,4-Trimethylpentane - CAS 540-84-1 (PDF)(2 pp, 32 K)
Vinyl Acetate - CAS 108-05-4 (PDF)(4 pp, 102 K)
Vinyl Bromide - CAS 593-60-2 (PDF)(4 pp, 110 K)
Vinyl Chloride - CAS 75-01-4 (PDF)(6 pp, 289 K)
Vinylidene Chloride (1,1-Dichloroethylene) - CAS 75-35-4 (PDF)(4 pp, 76 K)
Xylenes (Mixed Isomers) o-Xylene m-Xylene p-Xylene - CAS 1330-20-7, 95-47-6, 108-38-3, 106-42-3 (PDF)(5 pp, 81 K)

Health Effects Notebook

Related Links