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Integrated Risk Information System

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Integrated Risk Information System

EPA’s mission is to protect human health and the environment. EPA’s IRIS Program supports this mission by identifying and characterizing the health hazards of chemicals found in the environment. Each IRIS assessment can cover a chemical, a group of related chemicals, or a complex mixture.

Basic Information

IRIS Assessments

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Program Materials

Related Resources

Recent Additions

11/30: IRIS Handbook (Public Comment Draft) Federal Register Notice 90-day public comment period
11/09: IRIS Handbook (Public Comment Draft)
10/30: IRIS Program Outlook October 2020
10/5-6: Physiologically Based Pharmacokinetic (PBPK) Modeling for Chloroprene and a Supplemental Analysis of Metabolite Clearance (Draft Report) Public Meeting
07/28: Update to the Systematic Review Protocol for the PFAS IRIS Assessments

More IRIS Recent Additions

IRIS Calendar