An official website of the United States government.

This is not the current EPA website. To navigate to the current EPA website, please go to This website is historical material reflecting the EPA website as it existed on January 19, 2021. This website is no longer updated and links to external websites and some internal pages may not work. More information »

Pesticide Registration

PRN 2017-2: Guidance for Herbicide-Resistance Management, Labeling, Education, Training, and Stewardship

PRN 2017-2, Guidance for Herbicide Resistance Management Labeling, Education, Training, and Stewardship, applies to herbicides only. PRN 2017-2 communicates the Agency’s current thinking and approach to addressing herbicide-resistant weeds by providing guidance on labeling, education, training, and stewardship for herbicides undergoing registration review or registration (i.e., new herbicide active ingredients, new uses proposed for use on herbicide-resistant crops or other case-specific registration actions).

PRN 2017-2 provides 11 elements focused on labeling, education, training and stewardship strategies. Herbicides posing the least risk of developing herbicide-resistant weeds will have the fewest resistance management elements, and herbicides that pose the greatest risk of resistance will have the most elements. 

You may need a PDF reader to view some of the files on this page. See EPA’s About PDF page to learn more.