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Mouse Lung Tumor Workshop (Jan 2014): Meeting Materials

EPA conducted a State-of-the-Science Workshop on Chemically-induced Mouse Lung Tumors: Applications to Human Health Assessments. The purpose of this workshop was to discuss the available data and interpretation of results from studies of mouse bronchiolar-alveolar adenomas and carcinomas (lung tumors) following exposure to chemical agents, and the relevance of such tumors in mice to human cancer risk. Several lines of research have investigated whether or not these types of lung tumors are formed by a mode of action (MOA) which is specific to mice and are relevant to tumor formation or other toxicity in humans.

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