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Guidance Documents Managed by the Office of Chemical Safety and Pollution Prevention (OCSPP)


This page displays a list of all documents managed by the Office of Chemical Safety and Pollution Prevention and designated as guidance documentsHelpGuidance DocumentsAgency statements of general applicability, intended to have future effects on the behavior of regulated parties, that set forth a policy on a statutory, regulatory, or technical issue, or an interpretation of a statute or regulation, with some exceptions as detailed in E.O. 13891, Section 2(b).  EPA's guidance documents lack the force and effect of law, unless expressly authorized by statute or incorporated into a contract. The agency may not cite, use, or rely on any guidance that is not posted on this website, except to establish historical facts.
 

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Document Name
(click on link to view)
Original Issue Date Date Added to this List Identifier Topics Description/Summary Division Assigned ID
870 Toxicology Guidelines 2019-12-12 2020-02-28 EPA 705-G-2020-2564 FIFRA, Pesticides, Antimicrobial This document explains the toxicology guidelines. OPP AD 2564
875 Exposure Guidelines 2016-08-25 2020-02-28 EPA 705-G-2020-2565 FIFRA, Pesticides, Antimicrobial This document explains the exposure guidelines. OPP AD 2565
875.1700 Product Use Information (Applicator) 1996-02-01 2020-02-28 EPA 705-G-2020-2365 FIFRA, Pesticides, Antimicrobial This document explains pest use information. OPP AD 2365
875.2800 Descriptions of Human Activity.  2009-07-30 2020-02-28 EPA 705-G-2020-2368 FIFRA, Pesticides, Antimicrobial This document explains the description of human activities testing guidelines. OPP AD 2368
Acute Toxicity Templates for Antimicrobial Products 2017-04-25 2020-02-28 EPA 705-G-2020-2626 FIFRA, Pesticides, Antimicrobial These templates are designed to guide registrants in required acute toxicity studies. OPP AD 2626
Adding the NSF Logo to Antimicrobial Product Labels 2016-09-09 2020-02-28 EPA 705-G-2020-1298 Pesticide Labels Upon receipt of certification from NSF, a registrant may submit a request to add the logo via the Agency’s notification process as described in PR Notice 98-10. OPP AD 1298
Alternate Testing Framework for Classification of Eye Irritation Potential of EPA-Regulated Pesticide Products 2017-05-24 2020-02-28 EPA 705-G-2020-1272 Pesticide Registration EPA has updated guidance on testing antimicrobial cleaning products for potential eye irritation. This guidance relies on non-animal testing and expands the use of certain tests. OPP AD 1272
Antimicrobial Performance Evaluation Program (APEP) 2019-11-21 2020-02-28 EPA 705-G-2020-3561 FIFRA, Antimicrobial This document explains the APEP program, it supersedes the ATP guidance OPP AD 3561
Antimicrobial Pesticide Registration 2019-04-04 2020-02-28 EPA 705-G-2020-0414 Pesticide Registration Resources for an individual or company wanting to register an antimicrobial pesticide. OPP AD 414
Antimicrobial Pesticides 2016-11-15 2020-02-28 EPA 705-G-2020-3509 FIFRA; Pesticides; Antimicrobial; Website detailing guidance documents for registration OPP AD 3509
Antimicrobial Policy and Guidance Documents 2017-09-26 2020-02-28 EPA 705-G-2020-1486 Pesticide Registration These policies and guidance resources are intended to assist companies that want to register an antimicrobial pesticide. OPP AD 1486
Antimicrobial Products Registered for Disinfection Use against Avian Influenza on Poultry Farms and Other Facilities 2019-12-18 2020-02-28 EPA 705-G-2020-2608 FIFRA, Antimicrobial This document provides guidance on the avian on use of antimicrobial products in poultry farms and other facilities. OPP AD 2608
Antimicrobial Testing Methods & Procedures: MB-35-00 2017-03-21 2020-02-28 EPA 705-G-2020-1667 Pesticide Analytical Methods Information about ATMP - OECD Quantitative Method for Evaluating the Efficacy of Liquid Antimicrobials against Candida auris on Hard, Non-Porous Surfaces - MB-35-00 OPP AD 1667
Antimicrobial Testing Program 2018-12-10 2020-02-28 EPA 705-G-2020-2637 FIFRA, ATP, antimicrobial Details of ATP including status table. OPP AD 2637
Antimicrobials Used in the Fermentation of Fuel Ethanol – Clarification of Jurisdiction 2016-11-02 2020-02-28 EPA 705-G-2020-1462 FIFRA; Pesticides; Antimicrobial; EPA has determined that antimicrobials applied to processed food or feed during fermentation of organic material to produce fuel ethanol are outside the scope of EPA’s regulatory authority under FIFRA. The Food and Drug Administration has jurisdiction. OPP AD 1462
Conduct of Acute Toxicity Studies 1997-09-01 2020-02-28 EPA 705-G-2020-3392 FIFRA; pesticides; antimicrobial This document details the procedure for conducting acute toxicity studies. OPP AD 3392
Confirmatory Virucidal Effectiveness Test for Feline Calicivirus (FCV) 2017-12-27 2020-02-28 EPA 705-G-2020-2620 FIFRA, Antimicrobial This document describes how to achieve efficacy of pre-saturated or impregnated towelettes for hard, non-porous surface disinfection against feline calicivirus (FCV), surrogate for norovirus. OPP AD 2620
Consideration of Prions as a Pest under FIFRA 2003-09-10 2020-02-28 EPA 705-G-2020-1467 FIFRA, Antimicrobial This is the record of decision regarding prions should be considered to be a “pest” the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), as amended. It includes information about EPA regulation of pesticides based on this decision. OPP AD 1467
Consumer Products Treated with Pesticides 2018-05-29 2020-02-28 EPA 705-G-2020-2638 FIFRA, Antimicrobial This explains the treated article exemption OPP AD 2638
Design for the Environment Logo for Antimicrobial Pesticide Products 2019-05-21 2020-02-28 EPA 705-G-2020-3513 FIFRA; Pesticides; Antimicrobial; This document explains designed for the environment on antimicrobial products. OPP AD 3513
Determining If A Cleaning Product Is a Pesticide Under FIFRA 2019-07-03 2020-02-28 EPA 705-G-2020-2628 FIFRA, Antimicrobial This fact sheet describes the Agency's longstanding interpretation of the statutory and regulatory language applicable to products marketed as cleaning products that claim, state or imply (by labeling or other means) that they mitigate a pest. OPP AD 2628
Draft Guidance on Conducting an Ecological Exposure Assessment for Antifoulant Coatings & Paints— Saltwater Marinas. June 2016 2016-06-01 2020-02-28 EPA 705-G-2020-2392 marinas, antifoulants, copper, FIFRA SOP for estimating exposures for antifoulant paints in coastal marinas. Master OPP AD 2392
E-FAST, Down the Drain Assessment Model 2007-10-01 2020-02-28 EPA 705-G-2020-2394 down the drain, WWTP, wastewater, E-FAST, FIFRA Model developed by OPPT and used by AD to estimate aquatic exposures from pesticidal chemicals which are disposed of down the drain either in municipal or industrial waste water systems. Manual updated in 2015. Master OPP AD 2394
Efficacy Testing Standards for Antimicrobial Product Data Call-In Responses 2017-05-11 2020-02-28 EPA 705-G-2020-1458 FIFRA, Antimicrobial One of the objectives of reregistration is for the Agency to ensure that antimicrobial pesticide products are supported by acceptable efficacy data. Find out about the standards data must meet for antimicrobial products subject to reregistration. OPP AD 1458
Efficacy Testing Standards for Reregistration 2017-05-11 2020-02-28 EPA 705-G-2020-2597 data-call-in; reregistration This document provides an overview of the 2014 efficacy data standards and identifies certain testing standards that differ from the 2012 Guidelines.  It is intended for registrants citing/submitting previously generated or new efficacy data in response to a reregistration data call-in OPP AD 2597
Emerging Viral Pathogen Guidance for Antimicrobial Pesticides 2017-07-31 2020-02-28 EPA 705-G-2020-1519 Pesticide Registration The guidance outlines a voluntary, two stage process involving product label amendments and modified terms of registration and applies only to emerging viruses. OPP AD 1519
EPA Data Requirements for Registration of Antimicrobial Pesticides: 158W Implementation Letter 2017-05-05 2020-02-28 EPA 705-G-2020-1264 Pesticide Registration This letter informs pesticide registrants how EPA has been implementing new data requirements under 40 CFR Part 158W. OPP AD 1264
EPA Data Requirements for Registration of Antimicrobial Pesticides: Part 158W 2019-05-03 2020-02-28 EPA 705-G-2020-1262 Pesticide Registration; FIFRA; Pesticides; Antimicrobial; This document gives the data requirements for antimicrobial products. OPP AD 1262
Fogger and Mister Final Signed Letter 2013-04-01 2020-02-28 EPA 705-G-2020-1461 Pesticide Registration EPA has asked pesticide companies to provide data or amend registrations of products claiming to control public health microorganisms when applied by fogging and/or misting methods. The letter further describes the ways in which the company may respond. OPP AD 1461
Fragrance Notification Programs 2015-12-01 2020-02-28 EPA 705-G-2020-2600 FIFRA, Antimicrobial This document provides guidance for EPA's Office of Pesticide Programs (OPP) Fragrance Notification Program (PFNP) for registrants seeking to add or modify existing fragrances in new or currently registered pesticide products. OPP AD 2600
Frequent Questions for the 2018 Series 810 – Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines  2019-08-28 2020-02-28 EPA 705-G-2020-3559 FIFRA, antimicrobial An FAQ for the 810 guidelines OPP AD 3559
Guidance Document Label Claims for Products with ATP failures 2018-12-10 2020-02-28 EPA 705-G-2020-2386 FIFRA, Antimicrobial Master, this document explains label guidance for ATP failures OPP AD 2386
Guidance for Antimicrobial Pesticide Products with Mold-Related Label Claims 2012-12-12 2020-02-28 EPA 705-G-2020-2636 FIFRA, Antimicrobial This document represents the Agency's guidance on product performance data and labeling for "mold-related" pesticide products. OPP AD 2636
Guidance for Pre-Application Meetings on New Active Ingredients, Major New Uses and Other Registration Actions 2019-09-05 2020-02-28 EPA 705-G-2020-1479 Pesticide Registration This is to provide guidance to OPP/AD staff concerning meetings with companies that are considering submitting an application involving a new active ingredient, new use, new technology. OPP AD 1479
Guidance for quantitative assessment of dermal sensitization risk for pesticide chemicals in the Office of Pesticide Programs 2019-09-04 2020-02-28 EPA 705-G-2020-2377 FIFRA, Antimicrobial This document explains assessment of dermal sensitization. OPP AD 2377
Guidance for Reregistration of Pesticides containing Sodium and Calcium Hypochlorite Salts as the Active Ingredient  1986-02-01 2020-02-28 EPA 705-G-2020-2396 FIFRA, Antimicrobial The 1986 standard for Sodium and Calcium hypochlorite  OPP AD 2396
Guidance For The Reregistration Of Wood Preservative Pesticide Products Containing Chromated And Non-Chromated Arsenicals as the Active Ingredient, Case Number 0647 1986-09-10 2020-02-28 EPA 705-G-2020-2391 FIFRA, Antimicrobial This document gives information for reregistration of chromated and non-chromated arsenicals. OPP AD 2391
Guidance for Use of Food-Grade Shell-Egg Sanitizers 2016-11-02 2020-02-28 EPA 705-G-2020-1463 FIFRA; Pesticides; Antimicrobial; Formulations must be cleared under 21 CFR 178.1010 as sanitizing solutions for food contact surfaces or have a tolerance or exemption from the requirement of a tolerance in 40 CFR Part 180 that covers use as a sanitizing solution for food contact surfaces. OPP AD 1463
Guidance for Waiving Acute Dermal Toxicity Tests for Pesticide Formulations & Supporting Retrospective Analysis 2016-11-09 2020-02-28 EPA 705-G-2020-3391 acute, dermal, toxicity,  This document details the procedure for waiving acute dermal toxicity tests. OPP AD 3391
Guidance for Waiving or Bridging of Mammalian Acute Toxicity Tests for Pesticides and Pesticide Products (Acute Oral, Acute Dermal, Acute Inhalation, Primary Eye, Primary Dermal, and Dermal Sensitization) 2012-03-01 2020-02-28 EPA 705-G-2020-2376 FIFRA, Antimicrobial This document gives information on waiving or bridging acute tox data (master) OPP AD 2376
Guidance on Disinfectant Products Intended to Treat Drinking Water 2017-10-17 2020-02-28 EPA 705-G-2020-1712 FIFRA, Antimicrobial Guidance provides a basic overview of FIFRA product registration process and how FIFRA approval relates to the Safe Drinking Water Act, specifically for disinfectant products intended to treat. OPP AD 1712
Guidance on Warranty Statements 2006-10-17 2020-02-28 EPA 705-G-2020-2633 FIFRA, Antimicrobial This document contains information regarding acceptable warranty and disclaimer statements. OPP AD 2633
Guidance to Companies on Referring to Registered Disinfectant (Enterovirus D68) 2019-05-13 2020-02-28 EPA 705-G-2020-1460 FIFRA, Antimicrobial EPA has worked closely with Center for Disease Control (CDC) to develop the CDC recommendations for environmental infection control in healthcare settings against Enterovirus D68 (EV-D68). OPP AD 1460
Guidance to Companies on Referring to Registered Disinfectant Products that Meet the CDC Criteria for Use Against the Ebola Virus 2017-10-13 2020-02-28 EPA 705-G-2020-1459 FIFRA; Pesticides; Antimicrobial; There are no EPA-registered products with label claims against the Ebola virus, but enveloped viruses such as Ebola are susceptible to many hospital disinfectants used to disinfect hard, non-porous surfaces. CDC guidance addresses use of such products. OPP AD 1459
Guidance to Registrants: Process for Making Claims Against Emerging Viral Pathogens not on EPA-Registered Disinfectant Labels 2017-10-03 2020-02-28 EPA 705-G-2020-1474 FIFRA, Antimicrobial This guidance proposes to use an organism hierarchy to identify effective products for use with emerging pathogens and to permit registrants to make limited statements against such pathogens. It provides general guidance to interested parties. OPP AD 1474
Guidelines for Voluntary Disclosure of Antimicrobial Ingredient Information on Company Websites and/or Labels 2019-03-28 2020-02-28 EPA 705-G-2020-2601 FIFRA, Antimicrobial This document gives information on inert disclosure OPP AD 2601
How to Apply for the DfE Logo for Antimicrobial Pesticide Products 2019-05-21 2020-02-28 EPA 705-G-2020-1297 FIFRA; Pesticides; Antimicrobial; This document explains how to apply for a designed for the environment logo on AD products. OPP AD 1297
Indirect Dietary Residential Exposure Assessment Model (IDREAM) Implementation 2019-09-05 2020-02-28 EPA 705-G-2020-1345 FIFRA, Antimicrobial The Indirect Dietary Residential Exposure Assessment Model (IDREAM) estimates indirect ingestion exposure to disinfectants used in residential settings on hard surfaces where there may be inadvertent transfer to edible items prepared on those surfaces. OPP AD 1345
Interim Guidance for the Efficacy Evaluation of Products for Claims against Candida auris 2017-05-24 2020-02-28 EPA 705-G-2020-1668 FIFRA, Antimicrobial EPA has developed two new test methods and associated testing guidance for evaluating the effectiveness of antimicrobial pesticides against Candida auris (C. auris). OPP AD 1668
Methods and Guidance for Testing the Efficacy of Antimicrobial Products Against Biofilms on Hard, Non-Porous Surfaces 2017-10-19 2020-02-28 EPA 705-G-2020-1702 FIFRA, Antimicrobial Guidance document to assess the efficacy of antimicrobial pesticides hard non-porous surfaces. OPP AD 1702
Methods and Guidance for Testing the Efficacy of Antimicrobial Products Against Spores of Clostridium difficile on Hard Non-Porous Surfaces (February 2018) 2019-02-25 2020-02-28 EPA 705-G-2020-1261 FIFRA, Antimicrobial This document provides an update to the Agency’s interim guidance for the efficacy evaluation of antimicrobial pesticides that are labeled for treating hard non-porous surfaces in healthcare settings contaminated with spores of Clostridium difficile. OPP AD 1261
Mixtures Equation Pilot Program to Reduce Animal Testing 2017-05-10 2020-02-28 EPA 705-G-2020-1639 FIFRA, Antimicrobial EPA is announcing the start of a pilot program to evaluate the usefulness and acceptability of a mathematical tool (the GHS Mixtures Equation), which is used in the Globally Harmonized System of Classification and Labeling of Chemicals (GHS). OPP AD 1639
New EPA Quick Guide for Registering Disinfectant Products for Drinking Water Use 2017-10-17 2020-02-28 EPA 705-G-2020-1715 FIFRA, Antimicrobial Developed this Quick Guide for Disinfectant Products for Drinking Water Use in response to requests to help prospective pesticide registrants gain a basic understanding of the FIFRA. OPP AD 1715
Pesticide Assessment Guidelines Subdivision F Hazard Evaluation:  Human and Domestic Animals 1984-11-01 2020-02-28 EPA 705-G-2020-3389 FIFRA; pesticides; antimicrobials This document explains the hazard evaluation process for humans and domestic animals OPP AD 3389
Pesticide Label Statements:  Pilot Program to Help Promote Environmental Stability 2017-05-04 2020-02-28 EPA 705-G-2020-3534 FIFRA; Pesticides; Antimicrobial; This document explains a pilot program to promote environmental stability OPP AD 3534
Pesticide Registration Manual: Chapter 4 - Additional Considerations for Antimicrobial Products 2019-10-28 2020-02-28 EPA 705-G-2020-0502 FIFRA, Antimicrobial This chapter provides additional guidance unique to antimicrobial pesticides that is not covered in the other chapters. OPP AD 502
Possible Product Chemistry Triggers for Confirmatory Efficacy Data 2017-02-21 2020-02-28 EPA 705-G-2020-2641 FIFRA, Antimicrobial Chemical Modifications that may trigger additional data requirements OPP AD 2641
Pre-Saturated or Impregnated Confirmatory Virucidal Effective Test against Norovirus 2017-12-27 2020-02-28 EPA 705-G-2020-2622 FIFRA, Antimicrobial This document describes how to achieve virucidal effectiveness for a product used to disinfect hard, non-porous surfaces contaminated with Norovirus OPP AD 2622
Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2000, General Considerations for Testing Public Health Antimicrobial Pesticides 2018-02-01 2020-02-28 EPA 712-C-17-002 FIFRA, Antimicrobial This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP AD 52
Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2100, Sterilants, Sporicides, and Decontaminants 2018-02-01 2020-02-28 EPA 712-C-17-003 FIFRA, Antimicrobial This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP AD 53
Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2200, Disinfectants for Use on Environmental Surfaces 2018-02-01 2020-02-28 EPA 712-C-17-004 FIFRA, Antimicrobial This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP AD 54
Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2300, Sanitizers for Use on Hard Surfaces--Efficacy Data Recommendations 2012-09-04 2020-02-28 EPA 712-C-07-091 FIFRA, Antimicrobial This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP AD 55
Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2400, Disinfectants and Sanitizers for Use on Fabrics and Textiles 2012-12-21 2020-02-28 EPA 730-C-11-003 FIFRA, Antimicrobial This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP AD 56
Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2500, Air Sanitizers 2012-12-21 2020-02-28 EPA 730-C-11-003 FIFRA, Antimicrobial This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP AD 57
Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2600, Disinfectants for Use in Water 2012-12-21 2020-02-28 EPA 730-C-11-003 FIFRA, Antimicrobial This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP AD 58
Product Performance Test Guidelines: Antimicrobial Efficacy Test Guidelines, 810.2700, Products with Prion-Related Claims 2012-12-01 2020-02-28 EPA 712-C-13-001 FIFRA, Antimicrobial This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP AD 59
Product Performance Test Guidelines: General, 810.1000, Overview, Definitions, and General Considerations 1998-03-01 2020-02-28 EPA 712–C–98–001 FIFRA, Antimicrobial This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP AD 51
Product Registration Batching Guidance for Quaternary Ammonium Compounds (Cases 03503 and 3003)--Acute Mammalian Toxicity Data Requirements 1988-02-26 2020-02-28 EPA 705-G-2020-3390 acute, toxicity, DCI, quats This document identifies batches or groups of certain products which may rely on the same acute toxicity data to support product reregistration Data Call-In (DCI) requirements for quats. OPP AD 3390
Protocol for Residual Self-Sanitizing Activity of Dried Chemical Residues on Hard, Non-Porous Surfaces 2016-09-26 2020-02-28 EPA 705-G-2020-1471 FIFRA, Antimicrobial This protocol can be used to determine the residual sanitizing efficacy of antimicrobial products after application to inanimate, nonporous, non-food contact hard surfaces. OPP AD 1471
Protocol for Room Sterilization by Fogger Application 2016-09-26 2020-02-28 EPA 705-G-2020-1457 FIFRA, Antimicrobial This protocol describes an end-use fogging application for sterilizing porous and non-porous surfaces within a sealed and enclosed space. OPP AD 1457
Protocols for Testing the Efficacy of Disinfectants Against Hepatitis B Virus (HBV) 2018-04-02 2020-02-28 EPA 705-G-2020-1464 FIFRA, Antimicrobial EPA has endorsed the in vitro (test tube) duck assay as the appropriate and preferred alternative to animal testing. OPP AD 1464
Questions about the DfE Logo for Antimicrobial Pesticide Products 2019-05-21 2020-02-28 EPA 705-G-2020-3535 FIFRA; Pesticides; Antimicrobial; This document gives answers to common questions on DfE OPP AD 3535
Reregistration and Other Review Programs Predating Pesticide Registration Review 2017-05-24 2020-02-28 EPA 705-G-2020-3537 FIFRA; Pesticides; Antimicrobial; This document gives information on reregistration OPP AD 3537
Reregistration Eligibility Document Sodium and Calcium Hypochlorite Salts 1992-02-01 2020-02-28 EPA 705-G-2020-2395 FIFRA, Antimicrobial RED for Sodium and Calcium hypochlorite (aka bleach) OPP AD 2395
Review Process for the Registration and Use Directions for Floor Wipe Towelette Products 2016-12-06 2020-02-28 EPA 705-G-2020-1492 FIFRA, Antimicrobial This guidance provides Antimicrobials Division staff with guidance related to the registration requirements and use directions for presaturated/impregnated floor wipe towelette products. This document will be used for new and existing wipe registrations. OPP AD 1492
Revisions to the Performance Standard for AOAC Use Dilution Methods for Staphylococcus aureus and Pseudomonas aeruginosa 2013-11-26 2020-02-28 EPA 705-G-2020-2632 FIFRA, Antimicrobial Revisions to AOAC UDM to communication changes to performance standards for P. aeruginosa and S. aureus. OPP AD 2632
Series 860 Residue Chemistry Guidelines 2016-08-25 2020-02-28 EPA 705-G-2020-2563 FIFRA, Antimicrobial This document describes the residue chemistry guidelines for dietary analysis OPP AD 2563
Shock Letter for swimming pools, hot tubs, and spa products 2007-06-21 2020-02-28 EPA 705-G-2020-2617 FIFRA, Antimicrobial This is a letter that explains the term shock OPP AD 2617
Surface Safety Claims Guidance 2016-03-24 2020-02-28 EPA 705-G-2020-2618 FIFRA; Pesticides; Antimicrobial; This is a guidance document on surface safety claims OPP AD 2618
Surface Safety Claims Guidance Letter 2016-03-24 2020-02-28 EPA 705-G-2020-1455 FIFRA; Pesticides; Antimicrobial; This letter provides guidance on the use of surface safety claims on antimicrobial product labeling. OPP AD 1455
Test Method for the Continuous Reduction of Bacterial Contamination on Copper Alloy Surfaces 2016-01-29 2020-02-28 EPA 705-G-2020-2629 FIFRA, Antimicrobial This document explains the test method for continuous reduction of bacterial contamination OPP AD 2629
UDM Performance Standard Revision Document 2013-11-26 2020-02-28 EPA 705-G-2020-2598 FIFRA, Antimicrobial Explanation of changes to Use Dilution Method (UDM) OPP AD 2598
Updated Draft Protocol for the Evaluation of Bactericidal Activity of Hard, Non-porous Copper Containing Surface Products 2016-01-27 2020-02-28 EPA 705-G-2020-1472 FIFRA, Antimicrobial This document describes the updated draft testing protocol recommended by the EPA to support the registration of copper-containing surface products (such as door knobs, or other items that are not intended for food contact) that bear sanitizer claims. OPP AD 1472
Use of Disinfectants and Sanitizers in Heating, Ventilation, Air Conditioning, and Refrigeration Systems 2010-09-20 2020-02-28 EPA 705-G-2020-1465 FIFRA; Pesticides; Antimicrobial; This document brings attention several concerns that the Agency has regarding the use of sanitizer and/or disinfectant products, and other types of antimicrobial products, to treat the surfaces of heating, ventilation OPP AD 1465
Use of the Term "Germs" on Antimicrobial Labels 2005-01-05 2020-02-28 EPA 705-G-2020-1302 FIFRA; Pesticides; Antimicrobial; EPA response letter to CSPA providing guidance on when the term “germs” can be used on an antimicrobial label. OPP AD 1302
Use of the term "shock" on non-pesticide labeling 2008-07-24 2020-02-28 EPA 705-G-2020-2607 FIFRA, Antimicrobial This document explains how the term shock is used on non-pesticidal labeling. OPP AD 2607
Interim Guidance for the Efficacy Evaluation of Products for Claims Against Candida auris 2017-01-01 2020-02-28 EPA 705-G-2020-2520 Pesticide Analytical Methods The document provides criteria and references to test methods for developing efficacy data for antimicrobials against C. auris. OPP BEAD 2520
MB-19; Preparing a Pseudomonas aeruginosa or Staphylococcus aureus Biofilm using the CDC Biofilm Reactor 2019-11-25 2020-02-28 EPA 705-G-2020-3094 Antimicrobial Testing Methods Provides the laboratory procedure for growing a biofilm for efficacy testing of disinfectants. OPP BEAD 3094
MB-20; Single Tube Method for Determining the Efficacy of Disinfectants Against Bacterial Biofilm 2019-12-02 2020-02-28 EPA 705-G-2020-3097 Antimicrobial Testing Methods Provides a laboratory method for measuring the efficacy of disinfectants against bacterial biofilms. OPP BEAD 3097
MB-28; Procedure for the Production and Storage of Spores of Clostridium difficile for Use in the Efficacy Evaluation of Antimicrobial Agents  2017-12-08 2020-02-28 EPA 705-G-2020-3105 Antimicrobial Testing Methods Provides a laboratory method for producing spores of Clostridium difficile. OPP BEAD 3105
MB-31; Quantitative Method for Testing Antimicrobial Products Against Spores of Clostridium difficile on Inanimate, Hard, Non-porous Surfaces 2019-12-21 2020-02-28 EPA 705-G-2020-3107 Antimicrobial Testing Methods Provides a laboratory test method for evaluating antimicrobials for claims against clostridium difficile. OPP BEAD 3107
MB-35; OECD Quantitative Method for Evaluating the Efficacy of Liquid Antimicrobials Against Candida auris on Hard, Non-porous Surfaces  2018-01-09 2020-02-28 EPA 705-G-2020-3108 Antimicrobial Testing Methods Provides a laboratory test method for testing disinfectants for efficacy against Candida auris. OPP BEAD 3108
MB-37; Neutralization Confirmation for Evaluating the Efficacy of Liquid Antimicrobials against Candida auris using the OECD Quantitative Method on Hard, Non-porous Surfaces 2018-01-09 2020-02-28 EPA 705-G-2020-3109 Antimicrobial Testing Methods Provides a laboratory test method for determining the effectiveness of neutralizers in the Candida auris test method. OPP BEAD 3109
Methods and Guidance for the Efficacy Evaluation of Antimicrobial Products Against Biofilms on Hard, Non-porous Surfaces 2017-01-01 2020-02-28 EPA 705-G-2020-2521 Pesticide Analytical Methods The document provides criteria and references to test methods for developing efficacy data for antimicrobials against biofilm bacteria. OPP BEAD 2521
National Pesticide Standard Repository 2017-02-06 2020-02-28 EPA 705-G-2020-3077 Pesticides Information on how to obtain analytical standards from the EPA National Pesticide Standard Repository, which distributes analytical standards to federal, state and tribal laboratories involved in performing environmental, food, or product monitoring for the enforcement of United States federal and state pesticide laws such as the Federal Food, Drug, and Cosmetic Act and the Federal Insecticide, Fungicide, and Rodenticide Act. OPP BEAD 3077
Sporicidal Claims Against Clostridium difficile 2018-02-01 2020-02-28 EPA 705-G-2020-2519 FIFRA The document provides criteria and references to test methods for developing efficacy data for antimicrobials against C. difficile. OPP BEAD 2519
Suggestions for Applicants on Information Considered when Evaluating Benefits of New Conventional Active Ingredients/Significant New Use Site Requests 2018-09-01 2020-02-28 EPA 705-G-2020-3140 Antimicrobial Testing Methods This memo describes the types of benefits related information that would be useful for registrants to submit in support of their applications to register new conventional active ingredients or for significant new use requests. OPP BEAD 3140
The Role of Use-Related Information in Pesticide Risk Assessment and Risk Management 2000-10-11 2020-02-28 EPA 705-G-2020-0041 FIFRA Provides an overview of the role of pesticide use-related information in the regulatory process for risk assessment and risk management for pesticides. OPP BEAD 41
Use Dilution Method Performance Standard Revision Document 2013-11-26 2020-02-28 EPA 705-G-2020-2518 Pesticide Analytical Methods The performance standard for the UDM was reassessed in 2013; the document provides the statistical analysis and data supporting the change. OPP BEAD 2518
Active Ingredients Allowed in Minimum Risk Pesticide Products 2017-05-24 2020-02-28 EPA 705-G-2020-3384 Minimum Risk Pesticide; 40 CFR 152.25(f); Exemption; Active Ingredient; Composition; FFDCA; Tolerance Exemption Status The following active ingredients can be used in pesticide products that are exempt from the requirements of the Federal Insecticide, Fungicide, and Rodenticide Act under the minimum risk exemption regulations in 40 CFR 152.25(f). They can be used alone or in combination with other substances listed in this paragraph, provided that all of the criteria for minimum risk exemption are met. OPP BPPD 3384
Biochemicals Test Guidelines: OPPTS 880.1100 Product Identity and Composition 1996-02-01 2020-02-28 EPA 712-C-96-273 Test Guideline; Biochemical Pesticide; Product Identity; Composition; 880.1000 The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 368
Biochemicals Test Guidelines: OPPTS 880.1200 Description of Starting Materials, Production, and Formulation Process 1996-02-01 2020-02-28 EPA 712-C-96-274 Test Guideline; Biochemical Pesticide; Starting Materials; Production; Formulation Process; 880.1200 The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 369
Biochemicals Test Guidelines: OPPTS 880.1400 Discussion of Formation of Impurities 1996-02-01 2020-02-28 EPA 712-C-96-275 Test Guideline; Biochemical Pesticide; Impurities; 880.1400 The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 370
Biochemicals Test Guidelines: OPPTS 880.3550 Immunotoxicity 1996-02-01 2020-02-28 EPA 712-C-96-280 Test Guideline; Biochemical Pesticide; Immunotoxicity; 880.3550 The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 371
Biochemicals Test Guidelines: OPPTS 880.3800 Immune Response 1996-02-01 2020-02-28 EPA 712-C-96-281 Test Guideline; Biochemical Pesticide; Immune Response; 880.3800 The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 372
Biochemicals Test Guidelines: OPPTS 880.4350 Nontarget Insect Testing 1996-02-01 2020-02-28 EPA 712-C-96-285 Test Guideline; Biochemical Pesticide; Nontarget Insect Testing; 880.4350 The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 373
Biochemicals Test Guidelines: OPPTS 880.4425 Dispenser Water Leaching 1996-02-01 2020-02-28 EPA 712-C-96-286 Test Guideline; Biochemical Pesticide; Dispenser Water Leaching; 880.4425 The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 374
Biopesticide Registration 2017-04-12 2020-02-28 EPA 705-G-2020-0415 Pesticide Registration; Biopesticides; Pre-Submission Meetings; Regulatory and Data Requirements; Guidance Documents; Work Plans Resources for an individual or company wanting to register a biopesticide product to include biochemical pesticides, microbial pesticides, or plant-incorporated protectants. OPP BPPD 415
Biopesticides Confidential Statement of Formula 2010-01-05 2020-02-28 EPA 705-G-2020-0466 Pesticide Registration; Confidential Statement of Formula; Form 8570-4; Microbial Pesticides; Biochemical Pesticides This document describes how to prepare a confidential statement of formula (CSF) for biochemical and microbial pesticides. OPP BPPD 466
Biotech Information - Sharing Memorandum of Understanding 2000-02-02 2020-02-28 EPA 705-G-2020-1412 Biotechnology; Plant-Incorporated Protectants; Regulatory Oversight; Information Sharing; Memorandum of Understanding; FDA; USDA EPA, FDA, and the U.S. Department of Agriculture's Animal and Plant Health Inspection Service/Biotechnology Regulatory Services share the regulatory oversight over genetically engineered plants and the foods derived from such plants. OPP BPPD 1412
BPPD’s Risk Assessment Elements “Cheat Sheet” for Applicants 2019-09-01 2020-02-28 EPA 705-G-2020-3388 Risk Assessment; Product Uses; Use Rates; Toxic Effects; Open Scientific Literature Information; Qualitative; Quantitative; Aggregate When submitting a pesticide product registration application to EPA/OPP/BPPD, it is essential that you (applicant) address all applicable data requirements per the Code of Federal Regulations (CFR), part 158. However, it is also imperative that you (applicant) characterize your use sites, use patterns, rates and generally summarize your toxicity data so that a comprehensive risk assessment, taking into account all aspects of your product, can be performed by EPA. Often, when one or more of these pieces of information is missing from an application, the applicant is unsatisfied with the unavoidably conservative assessment that is performed. Further, presenting this information to EPA upfront can alleviate some unnecessary back-and-forth exchanges between EPA and the applicant and subsequent review time lost. EPA/BPPD highly recommends that applicants answer the following questions in writing in either a cover letter, data volume, or both when submitting their new product application. OPP BPPD 3388
Clarification of the Information Necessary to Determine the Formation of Unintended Ingredients in Microbial Pesticide Products 2019-05-06 2020-02-28 EPA 705-G-2020-2550 Unintentional Ingredients; Manufacturing Process; Microbial Pesticides; Critical Control Points; Quality Assurance; Quality Control; Contamination; Contaminants Data and information needed to satisfy the OCSPP Guidelines 885.1200 (manufacturing process) and 885.1300 (formation of unintentional ingredients) for new microbial active ingredients must be accompanied by a full description of the production process, ingredients used, and quality assurance (QA) and quality control (QC) measures. The intent of this document is to provide additional clarification to applicants of novel microbial pesticides and facilitate the development of complete submission packages.  OPP BPPD 2550
Commonly Consumed Food Commodities 2019-07-23 2020-02-28 EPA 705-G-2020-1096 Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Inert Ingredients; Commonly Consumed Food Commodities; Animal Feed Items; Edible Fats and Oils; 40 CFR 180.950  Commonly consumed foods are those ingested for their nutrient properties. Food commodities can be either raw agricultural commodities or processed commodities, provided that they are the forms that are sold or distributed for human consumption. Learn more about commonly consumed food commodities, as well as other items from 40 CFR 180.950 (e.g., animal feed items and edible fats and oils), and how they relate to minimum risk pesticides. OPP BPPD 1096
Conditions for Minimum Risk Pesticides 2018-03-14 2020-02-28 EPA 705-G-2020-1090 Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Composition; Label To qualify as minimum risk, a pesticide product must meet six conditions that relate to the ingredients in the product and claims that are made about the product on the label. Learn about these conditions. OPP BPPD 1090
Consumer Specialty Products Association Letter and EPA Response re: Minimum Risk Pesticide Exemption Petition 2017-03-27 2020-02-28 EPA 705-G-2020-1095 Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Public Health Pests; Consumer Specialty Products Association Petition The Consumer Specialty Products Association petitioned EPA to exclude from the minimum risk pesticide exemption pesticides claiming to control “pests of significant public health importance” and require registration. View the petition and EPA's response. OPP BPPD 1095
Design for the Environment Logo for Biopesticide Products  2019-05-21 2020-02-28 EPA 705-G-2020-3381 Pesticide Registration; Design for the Environment; Logo; Biopesticides Brief description of how to obtain the Design for the Environment (DoE) logo, what the DoE logo means on biopesticide product labels, and when the DoE logo can be used. OPP BPPD 3381
Determining If Insect Repellent Skin Patch Products Must Be Registered Under FIFRA 2018-04-02 2020-02-28 EPA 705-G-2020-1257 Pesticide Registration; Vitamin B; Biochemical Pesticides; Insect Repellent; Skin Patch; Minimum Risk Pesticides; 40 CFR 152.25(f); Enforcement Certain skin patch products that claim to repel insects are required to be registered under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), while others are exempt. Learn more about this issue. OPP BPPD 1257
Draft Guidance for Plant Regulator Label Claims, Including Plant Biostimulants 2019-03-25 2020-02-28 EPA 705-G-2020-2558 Plant Regulators; Claims; Plant Biostimulants; Plant Nutrients; Plant Inoculants; Soil Amendments; Vitamin-Hormone Products; Exclusions In recognition of the growing categories of products generally known as plant biostimulants, this document is intended to provide guidance on identifying product label claims that are considered to be plant regulator claims by the Agency, thereby subjecting the products to regulation as pesticides under FIFRA. OPP BPPD 2558
Enforcement Related to Minimum Risk Pesticides 2016-11-01 2020-02-28 EPA 705-G-2020-1093 Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Federal Enforcement; State Enforcement If a product does not meet all the requirements of the minimum risk exemption, it must be registered unless eligible for some other exemption. Learn about enforcement actions EPA can take where unregistered products make pesticidal claims. OPP BPPD 1093
EPA’s National Organic Program Guidance 2017-05-24 2020-02-28 EPA 705-G-2020-1417 Pesticide Registration; National Organic Program; Ingredients  The National Organic Program is a USDA program, including concerning the eligibility of inert ingredients for use in the NOP. EPA’s role is to assist USDA by assuring that USDA’s policies are implemented for organic claims by registered pesticide products. OPP BPPD 1417
EPA's Regulation of Biotechnology for Use in Pest Management 2019-12-23 2020-02-28 EPA 705-G-2020-2647 Pesticide Registration; Biotechnology; Plant-Incorporated Protectants; Genetically Modified Microbial Pesticides; Herbicide-Tolerant Crops; Risk Assessment; Gene Flow; Insect Resistance Management; USDA; FDA; Tolerance Exemptions; Data Requirements; FIFRA SAP To address the challenges of biotechnology, the Environmental Protection Agency (EPA), the U.S. Department of Agriculture (USDA), and the Food and Drug Administration (FDA) have shared responsibility for regulating agricultural biotechnology in the United States. In particular, EPA regulates pesticides created through biotechnology as a part of its regulatory jurisdiction over all pesticides marketed and used in the United States. As such, EPA has tailored its basic regulatory framework to fit the distinctive characteristics of these genetically engineered biological pesticides. A description of this framework is provided below.  OPP BPPD 2647
How to Apply for the DfE Logo for Biopesticide Products 2019-05-06 2020-02-28 EPA 705-G-2020-1296 Pesticide Labels; Design for the Environment; Logo; Biopesticides; Safer Choice This page lists the criteria a product must meet and provides instructions to apply for the DfE logo on biopesticide product labels. OPP BPPD 1296
How to Use OECD Data Evaluation Record Templates 2011-11-18 2020-02-28 EPA 705-G-2020-0517 Pesticide Registration; Joint Review; Canadian Pest Management Regulatory Agency; Data Templates; Microbial Pesticides This document describes the process of development of the OECD data evaluation record templates and provides examples of how to use them. OPP BPPD 517
Inert Ingredients Eligible for FIFRA 25(b) Pesticide Products 2016-11-16 2020-02-28 EPA 705-G-2020-3380 Minimum Risk Pesticide; 40 CFR 152.25(f); Inert Ingredient; Composition; Tolerance Exemption Status This list includes the inert ingredients that can be used in minimum risk pesticide products. OPP BPPD 3380
Information Needed to Support a Biochemical Classification Determination 2020-01-16 2020-02-28 EPA 705-G-2020-3387 Biochemical Pesticide; Biochemical Classification Committee; Criteria; Naturally Occurring Compound; Structurally Similar and Functionally Identical to Naturally Occurring Compound; Non-Toxic Mode of Action; History of Safe Exposure; Other Supporting Information Describes the information a prospective pesticide applicant needs to provide to EPA to allow it to make a determination whether a particular substance is a biochemical pesticide. OPP BPPD 3387
Insect Resistance Management for Bt Plant-Incorporated Protectants 2017-08-22 2020-02-28 EPA 705-G-2020-2547 Pesticide Registration; Biotechnology; Plant-Incorporated Protectants; Insect Resistance Management; Pyramids; Stacks; Refuge; Mitigation Strategies; Compliance Assurance Plans; Resistance Monitoring; Scientific Advisory Panels EPA places a high value on the efficacy of Bt PIPs and on preserving their significant agricultural and environmental benefits. Therefore, the Agency is committed to maintaining effective oversight of these products to mitigate the development of resistance in the target pests. To counter the threat of resistance, EPA has mandated the implementation of an Insect Resistance Management (IRM) plan for each commercially registered Bt PIP. The goal of IRM is to delay the onset of resistance for as long as possible, though it is important to note that it may not be possible to entirely prevent resistance from evolving.   OPP BPPD 2547
Introduction to Biotechnology Regulation for Pesticides 2017-06-06 2020-02-28 EPA 705-G-2020-2653 Pesticide Registration; Data; Biotechnology; Plant-Incorporated Protectants; Genetically Engineered Microbial Pesticides; Herbicide-Tolerant Plants; Gene Flow; Risk Assessments; Insect Resistance Management This document provides an overview of what biotechnology pesticide products are and how EPA evaluates them during the registration process. OPP BPPD 2653
Labeling of Pesticide Products under the National Organic Program 2017-05-24 2020-02-28 EPA 705-G-2020-1305 Pesticide Labels; National Organic Program; Logo This notice describes how registrants can obtain EPA approval of label language indicating that all ingredients in a pesticide product and all uses of that pesticide meet the criteria defined in the USDA National Organic Program Rule. OPP BPPD 1305
Memorandum on Modernizing the Regulatory System for Biotechnology Products 2015-07-02 2020-02-28 EPA 705-G-2020-1647 Biotechnology; Plant-Incorporated Protectants; Genetically Engineered Microbial Pesticides; Biotechnology Working Group; Coordinated Framework; FDA; USDA; Transparency; Predictability; Efficiency; Best Available Science; Strategy This July 2, 2015 memorandum initiated a process to modernize the federal regulatory system for the products of biotechnology and to establish mechanisms for periodic updates of that system. OPP BPPD 1647
Microbial Pesticide Test Guidelines: OCSPP 885.1250: Deposition of a Sample in a Nationally Recognized Culture Collection 2012-04-01 2020-02-28 EPA 712-C-12-027 Test Guideline; Microbial Pesticide; Culture Collection Deposition; 885.1250 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 213
Microbial Pesticide Test Guidelines: OPPTS 885.0001 Overview for Microbial Pest Control Agents 1996-02-01 2020-02-28 EPA 712-C-96-280 Test Guideline; Microbial Pesticide; Microbial Pesticide Testing Overview; 885.0001 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 255
Microbial Pesticide Test Guidelines: OPPTS 885.1100 Product Identity 1996-02-01 2020-02-28 EPA 712-C-96-273 Test Guideline; Microbial Pesticide; Product Identity; 885.1100 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 211
Microbial Pesticide Test Guidelines: OPPTS 885.1200 Manufacturing Process 1996-02-01 2020-02-28 EPA 712-C-96-293 Test Guideline; Microbial Pesticide; Manufacturing Process; 885.1200 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 212
Microbial Pesticide Test Guidelines: OPPTS 885.1300 Discussion of Formation of Unintentional Ingredients 1996-02-01 2020-02-28 EPA 712-C-96-294 Test Guideline; Microbial Pesticide; Unintentional Ingredients; 885.1300 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 214
Microbial Pesticide Test Guidelines: OPPTS 885.1400 Analysis of Samples 1996-02-01 2020-02-28 EPA 712-C-96-295 Test Guideline; Microbial Pesticide; Analysis of Samples; 885.1400 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 215
Microbial Pesticide Test Guidelines: OPPTS 885.1500 Certification of Limits 1996-02-01 2020-02-28 EPA 712-C-96-296 Test Guideline; Microbial Pesticide; Certification of Limits; 885.1500 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 216
Microbial Pesticide Test Guidelines: OPPTS 885.2000 Background for Residue Analysis of Microbial Pest Control Agents 1996-02-01 2020-02-28 EPA 712-C-96-299 Test Guideline; Microbial Pesticide; Residue Analysis Background; 885.2000 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 217
Microbial Pesticide Test Guidelines: OPPTS 885.2100 Chemical Identity 1996-02-01 2020-02-28 EPA 712-C-96-300 Test Guideline; Microbial Pesticide; Chemical Identity; Residues; 885.2100 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 218
Microbial Pesticide Test Guidelines: OPPTS 885.2200 Nature of the Residue in Plants 1996-02-01 2020-02-28 EPA 712-C-96-302 Test Guideline; Microbial Pesticide; Residue Nature in Plants; 885.2200 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 219
Microbial Pesticide Test Guidelines: OPPTS 885.2250 Nature of the Residue in Animals 1996-02-01 2020-02-28 EPA 712-C-96-303 Test Guideline; Microbial Pesticide; Residue Nature in Animals; 885.2250 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 220
Microbial Pesticide Test Guidelines: OPPTS 885.2300 Analytical Methods—Plants 1996-02-01 2020-02-28 EPA 712-C-96-304 Test Guideline; Microbial Pesticide; Residue; Analytical Methods; Plants; 885.2300 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 221
Microbial Pesticide Test Guidelines: OPPTS 885.2350 Analytical Methods—Animals 1996-02-01 2020-02-28 EPA 712-C-96-305 Test Guideline; Microbial Pesticide; Residue; Analytical Methods; Animals; 885.2350 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 222
Microbial Pesticide Test Guidelines: OPPTS 885.2400 Storage Stability 1996-02-01 2020-02-28 EPA 712-C-96-306 Test Guideline; Microbial Pesticide; Residue; Storage Stability; 885.2400 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 223
Microbial Pesticide Test Guidelines: OPPTS 885.2500 Magnitude of Residues in Plants 1996-02-01 2020-02-28 EPA 712-C-96-307 Test Guideline; Microbial Pesticide; Magnitude of Residues; Plants; 885.2500 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 224
Microbial Pesticide Test Guidelines: OPPTS 885.2550 Magnitude of Residues in Meat, Milk, Poultry, and Eggs 1996-02-01 2020-02-28 EPA 712-C-96-308 Test Guideline; Microbial Pesticide; Magnitude of Residues; Meat; Milk; Poultry; Eggs; 885.2550 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 225
Microbial Pesticide Test Guidelines: OPPTS 885.2600 Magnitude of Residues in Potable Water, Fish, and Irrigated Crops 1996-02-01 2020-02-28 EPA 712-C-96-309 Test Guideline; Microbial Pesticide; Magnitude of Residues; Potable Water; Fish; Irrigated Crops; 885.2600 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 226
Microbial Pesticide Test Guidelines: OPPTS 885.3000 Background-Mammalian Toxicity/Pathogenicity/Infectivity 1996-02-01 2020-02-28 EPA 712-C-96-314 Test Guideline; Microbial Pesticide; Background; Toxicity; Pathogenicity; Infectivity; Mammals; 885.3000 The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 227
Microbial Pesticide Test Guidelines: OPPTS 885.3050 Acute Oral Toxicity/Pathogenicity 1996-02-01 2020-02-28 EPA 712-C-96-315 Test Guideline; Microbial Pesticide; Acute Oral Toxicity and Pathogenicity; Mammals; 885.3050 The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 228
Microbial Pesticide Test Guidelines: OPPTS 885.3100 Acute Dermal Toxicity/Pathology 1996-02-01 2020-02-28 EPA 712-C-96-316 Test Guideline; Microbial Pesticide; Acute Dermal Toxicity and Pathology; Mammals; 885.3100 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 229
Microbial Pesticide Test Guidelines: OPPTS 885.3150 Acute Pulmonary Toxicity/Pathogenicity 1996-02-01 2020-02-28 EPA 712-C-96-317 Test Guideline; Microbial Pesticide; Acute Pulmonary Toxicity and Pathogenicity; Mammals; 885.3150 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 230
Microbial Pesticide Test Guidelines: OPPTS 885.3200 Acute Injection Toxicity/Pathogenicity 1996-02-01 2020-02-28 EPA 712-C-96-318 Test Guideline; Microbial Pesticide; Acute Injection Toxicity and Pathogenicity; Mammals; 885.3200 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 231
Microbial Pesticide Test Guidelines: OPPTS 885.3400 Hypersensitivity Incidents 1996-02-01 2020-02-28 EPA 712-C-96-320 Test Guideline; Microbial Pesticide; Hypersensitivity Incidents; 885.3400 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 232
Microbial Pesticide Test Guidelines: OPPTS 885.3500 Cell Culture 1996-02-01 2020-02-28 EPA 712-C-96-321 Test Guideline; Microbial Pesticide; Cell Culture; Mammals; 885.3500 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 233
Microbial Pesticide Test Guidelines: OPPTS 885.3550 Acute Toxicology, Tier II 1996-02-01 2020-02-28 EPA 712-C-96-322 Test Guideline; Microbial Pesticide; Mammals; Acute Toxicology; Tier II Testing; 885.3550 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 234
Microbial Pesticide Test Guidelines: OPPTS 885.3600 Subchronic Toxicity/Pathogenicity 1996-02-01 2020-02-28 EPA 712-C-96-323 Test Guideline; Microbial Pesticide; Mammals; Subchronic Toxicity and Pathogenicity; Tier II Testing; 885.3600 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 235
Microbial Pesticide Test Guidelines: OPPTS 885.3650 Reproductive/Fertility Effects 1996-02-01 2020-02-28 EPA 712-C-96-324 Test Guideline; Microbial Pesticide; Mammals; Reproductive and Fertility Effects; Tier III Testing; 885.3650 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 236
Microbial Pesticide Test Guidelines: OPPTS 885.4000 Background for Nontarget Organism Testing of Microbial Pest Control Agents 1996-02-01 2020-02-28 EPA 712-C-96-328 Test Guideline; Microbial Pesticide; Nontarget Organism Testing Background; 885.4000 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 237
Microbial Pesticide Test Guidelines: OPPTS 885.4050 Avian Oral, Tier I 1996-02-01 2020-02-28 EPA 712-C-96-329 Test Guideline; Microbial Pesticide; Avian Oral Toxicity and Pathogenicity; 885.4050 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 238
Microbial Pesticide Test Guidelines: OPPTS 885.4100 Avian Inhalation Test, Tier I 1996-02-01 2020-02-28 EPA 712-C-96-330 Test Guideline; Microbial Pesticide; Avian Inhalation Toxicity and Pathogenicity; 885.4100 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 239
Microbial Pesticide Test Guidelines: OPPTS 885.4150 Wild Mammal Testing, Tier I 1996-02-01 2020-02-28 EPA 712-C-96-331 Test Guideline; Microbial Pesticide; Wild Mammal Toxicity and Pathogenicity; 885.4150 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 240
Microbial Pesticide Test Guidelines: OPPTS 885.4200 Freshwater Fish Testing, Tier I 1996-02-01 2020-02-28 EPA 712-C-96-332 Test Guideline; Microbial Pesticide; Freshwater Fish Toxicity and Pathogenicity; 885.4200 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 241
Microbial Pesticide Test Guidelines: OPPTS 885.4240 Freshwater Aquatic Invertebrate Testing, Tier I 1996-02-01 2020-02-28 EPA 712-C-96-333 Test Guideline; Microbial Pesticide; Freshwater Invertebrate Toxicity and Pathogenicity; 885.4240 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 242
Microbial Pesticide Test Guidelines: OPPTS 885.4280 Estuarine and Marine Animal Testing, Tier I 1996-02-01 2020-02-28 EPA 712-C-96-334 Test Guideline; Microbial Pesticide; Estuarine and Marine Animal Toxicity and Pathogenicity; 885.4280 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 243
Microbial Pesticide Test Guidelines: OPPTS 885.4300 Nontarget Plant Studies, Tier I 1996-02-01 2020-02-28 EPA 712-C-96-335 Test Guideline; Microbial Pesticide; Nontarget Plant Testing; 885.4300 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 244
Microbial Pesticide Test Guidelines: OPPTS 885.4340 Nontarget Insect Testing, Tier I 1996-02-01 2020-02-28 EPA 712-C-96-336 Test Guideline; Microbial Pesticide; Nontarget Insect Toxicity and Pathogenicity; 885.4340 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 245
Microbial Pesticide Test Guidelines: OPPTS 885.4380 Honey Bee Testing, Tier I 1996-02-01 2020-02-28 EPA 712-C-96-337 Test Guideline; Microbial Pesticide; Honey Bee Toxicity and Pathogenicity; 885.4380 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 246
Microbial Pesticide Test Guidelines: OPPTS 885.4600 Avian Chronic Pathogenicity and Reproduction Test, Tier III 1996-02-01 2020-02-28 EPA 712-C-96-342 Test Guideline; Microbial Pesticide; Avian Chronic Pathogenicity and Reproduction; Tier III Testing; 885.4600 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 247
Microbial Pesticide Test Guidelines: OPPTS 885.4650 Aquatic Invertebrate Range Testing, Tier III 1996-02-01 2020-02-28 EPA 712-C-96-343 Test Guideline; Microbial Pesticide; Aquatic Invertebrate Range Testing; Tier III Testing; 885.4650 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 248
Microbial Pesticide Test Guidelines: OPPTS 885.4700 Fish Life Cycle Studies, Tier III 1996-02-01 2020-02-28 EPA 712-C-96-344 Test Guideline; Microbial Pesticide; Fish Life Cycle Studies; Tier III Testing; 885.4700 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 249
Microbial Pesticide Test Guidelines: OPPTS 885.4750 Aquatic Ecosystem Test 1996-02-01 2020-02-28 EPA 712-C-96-345 Test Guideline; Microbial Pesticide; Aquatic Ecosystem Test; Tier III Testing; 885.4750 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 250
Microbial Pesticide Test Guidelines: OPPTS 885.5000 Background for Microbial Pesticides Testing 1996-02-01 2020-02-28 EPA 712-C-96-056 Test Guideline; Microbial Pesticide; Environmental Expression Testing Background; Tier II Testing; 885.5000 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 251
Microbial Pesticide Test Guidelines: OPPTS 885.5200 Expression in a Terrestrial Environment 1996-02-01 2020-02-28 EPA 712-C-96-338 Test Guideline; Microbial Pesticide; Terrestrial Environment Expression; Tier II Testing; 885.5200  This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 252
Microbial Pesticide Test Guidelines: OPPTS 885.5300 Expression in a Freshwater Environment 1996-02-01 2020-02-28 EPA 712-C-96-339 Test Guideline; Microbial Pesticide; Freshwater Environment Expression; Tier II Testing; 885.5300 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 253
Microbial Pesticide Test Guidelines: OPPTS 885.5400 Expression in a Marine or Estuarine Environment 1996-02-01 2020-02-28 EPA 712-C-96-312 Test Guideline; Microbial Pesticide; Marine or Estuarine Environment Expression; Tier II Testing; 885.5400 This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP BPPD 254
Minimum Risk - Addition of an Inert Ingredient or Active Ingredient to the Exemption 2017-06-16 2020-02-28 EPA 705-G-2020-3382 Minimum Risk Pesticide; 40 CFR 152.25(f); Exemption; Adding Active or Inert Ingredients; Petition This information describes that EPA is looking to set up a streamlined process for adding ingredients to the minimum risk pesticide active or inert lists and how parties interested in adding a substance to the two lists can proceed in the meantime. OPP BPPD 3382
Minimum Risk Pesticide: Definition and Product Confirmation 2018-04-02 2020-02-28 EPA 705-G-2020-3383 Minimum Risk Pesticide; 40 CFR 152.25(f); Exemption Description of what a minimum risk pesticide is and a statement as to whether EPA will confirm minimum risk pesticide status. OPP BPPD 3383
Minimum Risk Pesticides 2019-04-30 2020-02-28 EPA 705-G-2020-0557 Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Composition; Label; Conditions; Enforcement The website provides information on the criteria that must be met for a product to qualify for the FIFRA exemption. OPP BPPD 557
Minimum Risk Pesticides - Inert Ingredient and Active Ingredient Eligibility under 40 CFR 152.25(f) 2018-03-19 2020-02-28 EPA 705-G-2020-3385 Minimum Risk Pesticide; 40 CFR 152.25(f); Exemption; Active Ingredient; Inert Ingredient; Eligibility; Composition Ingredients that are included on both the Minimum Risk Active Ingredient list and the Minimum Risk Inert Ingredients list may be used either as an active ingredient or an inert ingredient. However, the active ingredient and inert ingredient lists are not interchangeable. Unless the ingredient appears on both lists, it can only be used based on the list it appears on. OPP BPPD 3385
NAFTA Revised Procedures for Joint Review of Microbials and Semiochemicals 2002-07-17 2020-02-28 EPA 705-G-2020-1418 Biopesticides; Joint Review; Canadian Pest Management Regulatory Agency; Microbial Pesticides; Arthropod Semiochemicals; Pre-Submission Consultations; Time Frames; Data Requirements The Canadian Pest Management Regulatory Agency and EPA have established a process for the joint review of pest control products in which the new active ingredient is a microbial or an arthropod semiochemical (including pheromones). OPP BPPD 1418
National Strategy for Modernizing the Regulatory System for Biotechnology Products 2016-09-01 2020-02-28 EPA 705-G-2020-1646 Biotechnology; Plant-Incorporated Protectants; Genetically Engineered Microbial Pesticides; Biotechnology Working Group; Coordinated Framework; FDA; USDA; Transparency; Predictability; Efficiency; Best Available Science; Strategy This National Strategy for Modernizing the Regulatory System for Biotechnology Products sets forth a vision for ensuring that the federal regulatory system is prepared to efficiently assess the risks, if any, of the future products of biotechnology. OPP BPPD 1646
Need for Tolerances and Tolerance Exemptions for Minimum Risk Pesticides 2018-05-09 2020-02-28 EPA 705-G-2020-1092 Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Tolerances; Tolerance Exemptions; FFDCA The ingredients used in minimum risk products used on food, food crops, food contact surfaces, or animal feed commodities generally have a tolerance or tolerance exemption. Learn about tolerances and tolerance exemptions for minimum risk ingredients. OPP BPPD 1092
OECD Data Evaluation Record Templates 2011-11-18 2020-02-28 EPA 705-G-2020-0516 Pesticide Registration; Joint Review; Canadian Pest Management Regulatory Agency; Data Templates; Microbial Pesticides See information about OECD templates used for writing data evaluation record for submitting studies for pesticide registrations. OPP BPPD 516
Overview of Plant Incorporated Protectants 2019-05-20 2020-02-28 EPA 705-G-2020-2546 Pesticide Registration; Biotechnology; Plant-Incorporated Protectants; Data; Regulation History; Scientific Advisory Panels; Risk Assessment Plant-incorporated protectants are pesticidal substances produced by plants and the genetic material necessary for the plant to produce the substance. For example, scientists can take the gene for a specific Bt pesticidal protein and introduce the gene into the plant's genetic material. Then the plant manufactures the pesticidal protein that controls the pest when it feeds on the plant. Both the protein and its genetic material are regulated by EPA; the plant itself is not regulated. OPP BPPD 2546
Personal Insect Repellents and Minimum Risk Pesticides 2019-07-23 2020-02-28 EPA 705-G-2020-1094 Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); Insect Repellents; Sunscreen Components; FDA; Public Health Pests  An exempt pesticide product may not bear claims to control rodent, insect or microbial pests in a way that links the pests with specific disease. We are considering a proposal to remove personal mosquito and tick repellents from the minimum risk exemption. OPP BPPD 1094
Pesticide Registration Manual: Chapter 3 - Additional Considerations for Biopesticide Products 2017-05-23 2020-02-28 EPA 705-G-2020-0500 Pesticide Registration; Biopesticides; Biochemical Pesticides; Microbial Pesticides; Plant-Incorporated Protectants; Data Requirements; PRIA Review Phases; Genetically Modified Microbial Pesticides; Biotech Notifications Biopesticides are certain types of pesticides derived from such natural materials as animals, plants, bacteria, and certain minerals that fall into three major classes: microbial pesticides, plant-incorporated protectants, and biochemical pesticides. A separate chapter on biopesticides is included in this manual because there are different requirements for biopesticides that need to be explained in detail. This chapter should be referred to in conjunction with Chapter 2, “Registering a Pesticide Product.” OPP BPPD 500
Plant-Incorporated Protectants Data Symposium 2016-10-19 2020-02-28 EPA 705-G-2020-2545 Pesticide Registration; Data; Biotechnology; Plant-Incorporated Protectants; Human Health Risk Assessment; Environmental Risk Assessment; Insect Resistance Management; Coordinated Framework; FDA; USDA The symposium provided a forum for PIP developers, the agricultural sector and the general public to receive information firsthand on the scope of the scientific review process that determines the safety of PIPs and on the pesticide registration process as a whole. EPA, FDA and USDA representatives gave an overview of the regulatory system that applies to biotechnology in the United States in the context of the Coordinated Framework for Regulation of Biotechnology. OPP BPPD 2545
Risk Assessment and Weight-of-the Evidence (WOE): Outcome from Meeting Between the Biopesticide Industry Alliance (BPIA) and EPA’s Office of Pesticide Programs (OPP) 2020-02-13 2020-02-28 EPA 705-G-2020-3386 Risk Assessment; Weight-of-the-Evidence; Data; Rationale; I-DEEM; Tolerance; Tolerance Exemption; Nonfood Determination; FFDCA Outcome from meeting between BPIA and OPP to discuss what data are needed for a risk assessment, what BioDEEM is and when is it triggered, possibility of demonstrating an adequate margin of safety between actual exposure and an effect level, possible regulatory tools to implement a determination of safety, and how much data to present to EPA before an application is submitted.  OPP BPPD 3386
Sample Request for Additional Information to Support a FIFRA Determination Request 2020-01-27 2020-02-28 EPA 705-G-2020-2559 Microbial Products; Pesticide Determination Information sent to stakeholders, who ask EPA to make determinations as to whether their microbial products are pesticides. As these types of requests need to now be submitted under PRIA (as an M009), EPA does its best to provide guidance as to what needs to be submitted for a successful application: (1) complete composition of the product, (2) label and advertising associated with the product, (3) information that shows the microorganism(s) in the product has/have non-pesticidal activity, and (4) confirmation as to whether the microorganism(s) in the product is/are intergeneric or naturally occurring. OPP BPPD 2559
State Regulation of Minimum Risk Pesticides 2016-11-01 2020-02-28 EPA 705-G-2020-1091 Minimum Risk Pesticides; Exemption; 40 CFR 152.25(f); State Regulation The states are not required to permit the sale of an exempted product simply because it is exempted under federal pesticide law. OPP BPPD 1091
Tier-Based Testing for the Effects of Proteinaceous Insecticidal Plant-Incorporated Protectants 2007-04-06 2020-02-28 EPA 705-G-2020-2548 Pesticide Registration; Biotechnology; Plant-Incorporated Protectants; Nontarget Invertebrates; Environmental Risk Assessment; Data The purpose of this paper is to summarize scientific and regulatory information on nontarget invertebrate testing and evaluation of new products expressing insecticidal proteins in an ecological risk assessment. The information included provides a general discussion for conducting non-target invertebrate ecological risk assessments for crops expressing insecticidal proteins. OPP BPPD 2548
Tips for Avoiding Confidential Statement of Formula or Product Chemistry Issues with Biopesticides 2019-08-02 2020-02-28 EPA 705-G-2020-2549 Pesticide Registration; Confidential Statement of Formula; Form 8570-4; Microbial Pesticides; Biochemical Pesticides; Product Chemistry; Biochemical Classification Committee; Plant-Incorporated Protectants; Pre-Registration Meeting These recommendations may assist registrants in avoiding common mistakes when preparing and submitting biopesticide product chemistry data and the Confidential Statement of Formula (CSF). OPP BPPD 2549
Tips for Plant-Incorporated Protectant (PIP) Experimental Use Permit (EUP) Program Submission 2017-06-06 2020-02-28 EPA 705-G-2020-1410 Experimental Use Permits; Biotechnology; Plant-Incorporated Protectants; Acreage; Test Protocols; Objectives; Locations; Seed Increase Includes information to include in the program description and final program report, recommendations for calculating acreage, use of seed produced under PIP EUPs, and consultation with Biopesticides and Pollution Prevention Division. OPP BPPD 1410
[Fish or Oyster] Bioconcentration Factor (BCF) of [Test Compound] 2012-12-01 2020-02-28 EPA 705-G-2020-3310 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3310
Acute Dietary Toxicity of {TAI or EUP} to Avian Species - [name of species] 2004-05-01 2020-02-28 EPA 705-G-2020-3312 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3312
Acute Oral Toxicity of {TAI or EUP} to Avian Species - [name of species] 2004-05-01 2020-02-28 EPA 705-G-2020-3311 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3311
Acute Toxicity Effects of {TAI or EUP} on Earthworms 2004-05-01 2020-02-28 EPA 705-G-2020-3305 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3305
Acute Toxicity of {TAI or EUP} to Algae - [name of species] 2004-05-01 2020-02-28 EPA 705-G-2020-3316 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3316
Acute Toxicity of {TAI or EUP} to Aquatic Vascular Plants - [name of species] 2004-05-01 2020-02-28 EPA 705-G-2020-3315 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3315
Acute Toxicity of {TAI or EUP} to Fish - [name of species] 2004-05-01 2020-02-28 EPA 705-G-2020-3307 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3307
Acute Toxicity of {TAI or EUP} to Freshwater Invertebrates - [Daphnia sp.] 2004-05-01 2020-02-28 EPA 705-G-2020-3306 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3306
Acute Toxicity of {TAI or EUP} to Terrestrial Vascular Plant - [name of species - seed germination-root elongation/seedling emergence/vegetative vigour] 2004-05-01 2020-02-28 EPA 705-G-2020-3314 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3314
Adsorption and desorption of test compound in soils or sediments 2012-05-01 2020-02-28 EPA 705-G-2020-3294 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3294
Aerobic (or Anaerobic) Degradation in Aquatic Systems 2012-05-01 2020-02-28 EPA 705-G-2020-3300 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3300
Aerobic (or Anaerobic) Degradation in Soil of [test compound] 2012-05-01 2020-02-28 EPA 705-G-2020-3299 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3299
Analytical method for [analyte(s)] in [soil, water, air, or other environmental medium] 2012-12-01 2020-02-28 EPA 705-G-2020-3317 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3317
Aqueous Photolysis of [test compound] 2012-05-01 2020-02-28 EPA 705-G-2020-3297 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3297
Chronic Toxicity of {TAI or EUP} to Fresh Water Invertebrates - [Daphnia sp.] 2004-05-01 2020-02-28 EPA 705-G-2020-3308 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3308
Draft Test Guideline: Aquatic Food Chain Transfer 2017-01-01 2020-02-28 EPA 705-G-2020-1339 Test Guidelines for Pesticides and Toxic Substances The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 1339
Draft Test Guideline: Chironomid Sediment Toxicity Test 2017-01-01 2020-02-28 EPA 705-G-2020-1337 Test Guidelines for Pesticides and Toxic Substances The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 1337
Draft Test Guideline: Field Testing For Aquatic Organisms 2017-01-01 2020-02-28 EPA 705-G-2020-1342 Test Guidelines for Pesticides and Toxic Substances The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 1342
Draft Test Guideline: Fish Acute Toxicity Mitigated By Humic Acid 2017-01-01 2020-02-28 EPA 705-G-2020-1330 Test Guidelines for Pesticides and Toxic Substances The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 1330
Draft Test Guideline: Fish Life Cycle Toxicity 2017-01-01 2020-02-28 EPA 705-G-2020-1335 Test Guidelines for Pesticides and Toxic Substances The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 1335
Draft Test Guideline: Generic Freshwater Microcosm Test, Laboratory 2017-01-01 2020-02-28 EPA 705-G-2020-1340 Test Guidelines for Pesticides and Toxic Substances The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 1340
Draft Test Guideline: Mysid Chronic Toxicity Test 2017-01-01 2020-02-28 EPA 705-G-2020-1334 Test Guidelines for Pesticides and Toxic Substances The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 1334
Draft Test Guideline: Site-Specific Aquatic Microcosm Test, Laboratory 2017-01-01 2020-02-28 EPA 705-G-2020-1341 Test Guidelines for Pesticides and Toxic Substances The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 1341
Draft Test Guideline: Tadpole/Sediment Subchronic Toxicity Test 2017-01-01 2020-02-28 EPA 705-G-2020-1338 Test Guidelines for Pesticides and Toxic Substances The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 1338
Draft Test Guideline: Whole Sediment Acute Toxicity Invertebrates, Marine 2015-07-01 2020-02-28 EPA 705-G-2020-1336 Test Guidelines for Pesticides and Toxic Substances The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 1336
Ecological Effects Test Guidelines: 850.1000, Background and Special Considerations - Tests with Aquatic and Sediment-Dwelling Fauna and Aquatic Microcosms 2016-10-01 2020-02-28 EPA 712-C-16-014 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 210
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1010, Aquatic Invertebrate Acute Toxicity Test, Freshwater Daphnids 2016-10-01 2020-02-28 EPA 712-C-16-013 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 152
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1020, Gammarid Amphipod Acute Toxicity Test 2016-10-01 2020-02-28 EPA 712-C-16-012 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 153
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1025, Oyster Acute Toxicity Test 2016-10-01 2020-02-28 EPA 712-C-16-010 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 154
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1035, Mysid Acute Toxicity Test 2016-10-01 2020-02-28 EPA 712-C-16-011 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 155
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1045, Penaeid Acute Toxicity Test 2016-10-01 2020-02-28 EPA 712-C-16-009 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 156
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1055, Bivalve Acute Toxicity Test 2016-10-01 2020-02-28 EPA 712-C-16-006 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 157
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1075, Freshwater and Saltwater Fish Acute Toxicity Test 2016-10-01 2020-02-28 EPA 712-C-16-007 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 158
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1300, Daphnid Chronic Toxicity Test 2016-10-01 2020-02-28 EPA 712-C-16-005 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 161
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1350, [Reserved] 2015-07-01 2020-02-28 EPA 705-G-2020-0162 Test Guideline; Ecological Effects Draft guideline. FINAL Guideline has not yet been published. OPP EFED 162
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1400, Fish Early Life Stage Toxicity Test 2016-10-01 2020-02-28 EPA 712-C-16-008 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 164
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1500, [Reserved] 2015-07-01 2020-02-28 EPA 705-G-2020-0165 Test Guideline; Ecological Effects Draft guideline. FINAL Guideline has not yet been published. OPP EFED 165
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1710, Oyster Bioconcentration Factor (BCF) 2016-10-01 2020-02-28 EPA 712-C-16-004 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 167
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1730, Fish Bioconcentration Factor (BCF) 2016-10-01 2020-02-28 EPA 712-C-16-003 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 168
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1735, Spiked Whole Sediment 10-Day Toxicity Test, Freshwater Invertebrates 2016-10-01 2020-02-28 EPA 712-C-16-002 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 169
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1740, Spiked Whole Sediment 10-Day Toxicity Test, Saltwater Invertebrates 2016-10-01 2020-02-28 EPA 712-C-16-001 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 170
Ecological Effects Test Guidelines: Aquatic and Sediment-Dwelling Fauna, Aquatic Microcosm and Field Testing Test Guidelines, 850.1790, [Reserved] 2015-07-01 2020-02-28 EPA 705-G-2020-0171 Test Guideline; Ecological Effects Draft guideline. FINAL Guideline has not yet been published. OPP EFED 171
Ecological Effects Test Guidelines: Aquatic Fauna Test Guidelines, 850.1350, Mysid Chronic Toxicity Test 1996-04-01 2020-02-28 EPA 712-C-96-166 Public Draft; Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 163
Ecological Effects Test Guidelines: Aquatic Fauna Test Guidelines, 850.1500, Fish Life Cycle Toxicity 1996-04-01 2020-02-28 EPA 712-C-96-122 Public Draft; Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 166
Ecological Effects Test Guidelines: Aquatic Fauna Test Guidelines, 850.1790, Chironomid Sediment Toxicity Test 1996-04-01 2020-02-28 EPA 712-C-96-313 Public Draft; Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 172
Ecological Effects Test Guidelines: Field Test Data Reporting Guidelines, 850.6100, Environmental Chemistry Methods and Associated Independent Laboratory Validation  (Public draft was numbered 850.7100) 2012-01-01 2020-02-28 EPA 712-C-12-001 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 209
Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4100, Seedling Emergence and Seedling Growth 2012-01-01 2020-02-28 EPA 712-C-12-012 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 197
Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4150, Vegetative Vigor 2012-01-01 2020-02-28 EPA 712-C-12-011 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 198
Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4230, Early Seedling Growth Toxicity Test 2012-01-01 2020-02-28 EPA 712-C-12-010 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 199
Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4300, Terrestrial Plants Field Study 2012-01-01 2020-02-28 EPA 712-C-12-009 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 200
Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4400, Aquatic Plant Toxicity Test Using Lemna spp. 2012-01-01 2020-02-28 EPA 712-C-12-008 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 201
Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4450, Aquatic Plants Field Study 2012-01-01 2020-02-28 EPA 712-C-12-007 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 202
Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4500, Algal Toxicity 2012-01-01 2020-02-28 EPA 712-C-12-006 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 203
Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4550, Cyanobacteria (Anabaena flos-aquae) Toxicity 2012-01-01 2020-02-28 EPA 712-C-12-005 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 204
Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4600, Rhizobium-Legume Toxicity 2012-01-01 2020-02-28 EPA 712-C-12-004 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 205
Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4800, Plant Uptake and Translocation Test 2012-01-01 2020-02-28 EPA 712-C-12-002 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 206
Ecological Effects Test Guidelines: Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil Core Microcosm Test Guidelines, 850.4900, Terrestrial Soil-Core Microcosm Test 2012-01-01 2020-02-28 EPA 712-C-12-003 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 207
Ecological Effects Test Guidelines: Terrestrial Beneficial Insects, Invertebrates, and Soil and Wastewater Microorganisms Test Guidelines, 850.3020, Honey Bee Acute Contact Toxicity Test 2012-01-01 2020-02-28 EPA 712-C-12-019 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 190
Ecological Effects Test Guidelines: Terrestrial Beneficial Insects, Invertebrates, and Soil and Wastewater Microorganisms Test Guidelines, 850.3030, Honey Bee Toxicity of Residues on Foliage 2012-01-01 2020-02-28 EPA 712-C-12-018 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 191
Ecological Effects Test Guidelines: Terrestrial Beneficial Insects, Invertebrates, and Soil and Wastewater Microorganisms Test Guidelines, 850.3040, Field Testing for Pollinators 2012-01-01 2020-02-28 EPA 712-C-12-017 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 192
Ecological Effects Test Guidelines: Terrestrial Beneficial Insects, Invertebrates, and Soil and Wastewater Microorganisms Test Guidelines, 850.3100, Earthworm Subchronic Toxicity Test 2012-01-01 2020-02-28 EPA 712-C-12-016 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 193
Ecological Effects Test Guidelines: Terrestrial Beneficial Insects, Invertebrates, and Soil and Wastewater Microorganisms Test Guidelines, 850.3200, Soil Microbial Community Toxicity Test 2012-01-01 2020-02-28 EPA 712-C-12-015 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 194
Ecological Effects Test Guidelines: Terrestrial Beneficial Insects, Invertebrates, and Soil and Wastewater Microorganisms Test Guidelines, 850.3300, Modified Activated Sludge, Respiration Inhibition Test 2012-01-01 2020-02-28 EPA 712-C-12-014 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 195
Ecological Effects Test Guidelines: Terrestrial Wildlife Test Guidelines, 850.2000, Background and Special Considerations- Tests with Terrestrial Wildlife 2012-01-01 2020-02-28 EPA 712-C-12-026 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 183
Ecological Effects Test Guidelines: Terrestrial Wildlife Test Guidelines, 850.2100, Avian Acute Oral Toxicity Test 2012-01-01 2020-02-28 EPA 712-C-12-025 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 184
Ecological Effects Test Guidelines: Terrestrial Wildlife Test Guidelines, 850.2200, Avian Dietary Toxicity Test 2012-01-01 2020-02-28 EPA 712-C-12-024 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 185
Ecological Effects Test Guidelines: Terrestrial Wildlife Test Guidelines, 850.2300, Avian Reproduction Test 2012-01-01 2020-02-28 EPA 712-C-12-023 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 186
Ecological Effects Test Guidelines: Terrestrial Wildlife Test Guidelines, 850.2400, Wild Mammal Toxicity Testing 2012-01-01 2020-02-28 EPA 712-C-12-022 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 187
Ecological Effects Test Guidelines: Terrestrial Wildlife Test Guidelines, 850.2500, Field Testing for Terrestrial Wildlife 2012-01-01 2020-02-28 EPA 712-C-12-021 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 188
E-Submission Environmental Study Supplemental Files 2002-06-27 2020-02-28 EPA 705-G-2020-0490 Pesticide Registration; E-submission; Environmental Study Supplemental; Aquatic Toxicity Study This document provides standard format for electronic submission of supplemental data files in support of aquatic toxicity studies. OPP EFED 490
E-submission for avian reproduction studies 2002-06-01 2020-02-28 EPA 705-G-2020-0495 Pesticide Registration; E-submission Avian Reproduction Studies Guidance information about electronic submission for avian reproduction studies. OPP EFED 495
E-submission for surface water and groundwater field studies and monitoring data 2001-02-01 2020-02-28 EPA 705-G-2020-0497 Pesticide Registration; E-submission Surface Water Ground Water Monitoring Data Guidance information about electronic submission for surface water and groundwater field studies and monitoring data. OPP EFED 497
E-Submission for Terrestrial and Aquatic Plant Studies 2001-02-01 2020-02-28 EPA 705-G-2020-0496 Pesticide Registration; E-submission Terrestrial and Aquatic Plant Studies Guidance information about electronic submissions for terrestrial and aquatic plant studies. OPP EFED 496
Fate, Transport and Transformation Test Guidelines: Field Dissipation Test Guidelines, 835.6100, Terrestrial Field Dissipation 2008-10-01 2020-02-28 EPA 712-C-08-20 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 142
Fate, Transport and Transformation Test Guidelines: Field Dissipation Test Guidelines, 835.6200, Aquatic (Sediment) Field Dissipation 2008-10-01 2020-02-28 EPA 712-C-08-21 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 143
Fate, Transport and Transformation Test Guidelines: Field Dissipation Test Guidelines, 835.6300, Forestry Dissipation 2008-10-01 2020-02-28 EPA 712-C-08-22 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 144
Fate, Transport and Transformation Test Guidelines: Field Dissipation Test Guidelines, 835.6400, Combination and Tank Mixes Field Dissipation 2008-10-01 2020-02-28 EPA 712-C-08-23 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 145
Fate, Transport and Transformation Test Guidelines: Ground Water Monitoring Test Guidelines, 835.7100, Guidance for Prospective Ground-Water Monitoring Studies 2008-08-01 2020-02-28 EPA 712-B-10-001 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 146
Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2120, Hydrolysis [SUPERSEDES 835.2110] 2008-10-01 2020-02-28 EPA 712-C-08-012 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 111
Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2130, Hydrolysis as a Function of pH and Temperature 1998-01-01 2020-02-28 EPA 712-C-98-059 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 112
Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2210, Direct Photolysis Rate in Water by Sunlight 1998-01-01 2020-02-28 EPA 712-C-98-060 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 113
Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2240, Photodegradation in Water 2008-10-01 2020-02-28 EPA 712-C-08-013 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 114
Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2310, Maximum Direct Photolysis Rate in Air from UV/Visible Spectroscopy 1998-01-01 2020-02-28 EPA 712-C-98-066 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 115
Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2370, Photodegradation in Air 2008-10-01 2020-02-28 EPA 712-C-08-014 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 116
Fate, Transport and Transformation Test Guidelines: Laboratory Abiotic Transformation Test Guidelines, 835.2410, Photodegradation in Soil 2008-10-01 2020-02-28 EPA 712-C-08-015 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 117
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3100, Aerobic Aquatic Biodegradation 1998-01-01 2020-02-28 EPA 712-C-98-075 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 118
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3110, Ready Biodegradability 1998-01-01 2020-02-28 EPA 712-C-98-076 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 119
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3140, Ready Biodegradability - CO2 in Sealed Vessels (Headspace Test) [SUPERSEDES 835.3120] 2008-10-01 2020-02-28 EPA 712-C-08-001 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 120
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3160, Biodegradability in Sea Water 1998-01-01 2020-02-28 EPA 712-C-98-351 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 121
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3170, Shake Flask Die-Away Test 1998-01-01 2020-02-28 EPA 712-C-98-297 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 122
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3180, Sediment/Water Microcosm Biogradation Test 1998-01-01 2020-02-28 EPA 712-C-98-083 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 123
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3190, Aerobic Mineralization in Surface Water - Simulation Biodegradation Test 2008-10-01 2020-02-28 EPA 712-C-08-002 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 124
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3200, Zahn-Wellens/EMPA Test 1998-01-01 2020-02-28 EPA 712-C-98-084 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 125
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3210, Modified SCAS Test 1998-01-01 2020-02-28 EPA 712-C-98-085 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 126
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3215, Inherent Biodegradability - Concawe Test 2008-10-01 2020-02-28 EPA 712-C-08-003 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 127
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3220, Porous Pot Test 1998-01-01 2020-02-28 EPA 712-C-98-301 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 128
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3240, Simulation Test—Aerobic Sewage Treatment: A. Activated Sludge Units 2008-10-01 2020-02-28 EPA 712-C-08-004 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 129
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3260, Simulation Test—Aerobic Sewage Treatment: B. Biofilms 2008-10-01 2020-02-28 EPA 712-C-08-005 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 130
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3280, Simulation Tests to Assess the Primary and Ultimate Biodegradability of Chemicals Discharged to Wastewater 2008-10-01 2020-02-28 EPA 712-C-08-006 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 131
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3300, Soil Biodegradation 1998-01-01 2020-02-28 EPA 712-C-98-088 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 132
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3400, Anaerobic Biodegradability of Organic Chemicals 1998-01-01 2020-02-28 EPA 712-C-98-090 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 133
Fate, Transport and Transformation Test Guidelines: Laboratory Biological Transformation Test Guidelines, 835.3420, Anaerobic Biodegradability of Organic Compounds in Digested Sludge: By Measurement of Gas Production 2008-10-01 2020-02-28 EPA 712-C-08-007 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 134
Fate, Transport and Transformation Test Guidelines: Laboratory Transport Test Guidelines, 835.1110, Activated Sludge Sorption Isotherm 1998-01-01 2020-02-28 EPA 712-C-98-298 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 105
Fate, Transport and Transformation Test Guidelines: Laboratory Transport Test Guidelines, 835.1210, Soil Thin Layer Chromatography 1998-01-01 2020-02-28 EPA 712-C-98-047 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 106
Fate, Transport and Transformation Test Guidelines: Laboratory Transport Test Guidelines, 835.1220, Sediment and Soil Adsorption/Desorption Isotherm 1998-01-01 2020-02-28 EPA 712-C-98-048 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 107
Fate, Transport and Transformation Test Guidelines: Laboratory Transport Test Guidelines, 835.1230, Adsorption/Desorption (Batch Equilibrium) 2008-10-01 2020-02-28 EPA 712-C-08-009 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 108
Fate, Transport and Transformation Test Guidelines: Laboratory Transport Test Guidelines, 835.1240, Leaching Studies 2008-10-01 2020-02-28 EPA 712-C-08-010 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 109
Fate, Transport and Transformation Test Guidelines: Laboratory Transport Test Guidelines, 835.1410, Laboratory Volatility 2008-10-01 2020-02-28 EPA 712-C-08-011 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 110
Fate, Transport and Transformation Test Guidelines: Transformation Chemical-Specific Test Guidelines, 835.5045, Modified SCAS Test for Insoluble and Volatile Chemicals 1998-01-01 2020-02-28 EPA 712-C-98-097 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 139
Fate, Transport and Transformation Test Guidelines: Transformation Chemical-Specific Test Guidelines, 835.5154, Anaerobic Biodegradation in the Subsurface 1998-01-01 2020-02-28 EPA 712-C-98-098 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 140
Fate, Transport and Transformation Test Guidelines: Transformation Chemical-Specific Test Guidelines, 835.5270, Indirect Photolysis Screening Test: Sunlight Photolysis in Waters Containing Dissolved Humic Substances 1998-01-01 2020-02-28 EPA 712-C-98-099 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 141
Fate, Transport and Transformation Test Guidelines: Transformation in Water and Soil Test Guidelines, 835.4100, Aerobic Soil Metabolism 2008-10-01 2020-02-28 EPA 712-C-08-016 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 135
Fate, Transport and Transformation Test Guidelines: Transformation in Water and Soil Test Guidelines, 835.4200, Anaerobic Soil Metabolism 2008-10-01 2020-02-28 EPA 712-C-08-017 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 136
Fate, Transport and Transformation Test Guidelines: Transformation in Water and Soil Test Guidelines, 835.4300, Aerobic Aquatic Metabolism 2008-10-01 2020-02-28 EPA 712-C-08-018 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 137
Fate, Transport and Transformation Test Guidelines: Transformation in Water and Soil Test Guidelines, 835.4400, Anaerobic Aquatic Metabolism 2008-10-01 2020-02-28 EPA 712-C-08-019 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 138
Fate, Transport and Transformation Test Guidelines: Volatility from Soil Test Guidelines, 835.8100, Field Volatility 2008-10-01 2020-02-28 EPA 712-C-08-024 Test Guideline; Fate, Transport and Transformation The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 147
Field Dissipation of [test compound] 2012-05-01 2020-02-28 EPA 705-G-2020-3301 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3301
Field volatility of [test compound] 2012-12-01 2020-02-28 EPA 705-G-2020-3303 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3303
Guidance for Use When Regurgitation is Observed in Avian Acute Toxicity 2012-01-01 2020-02-28 EPA 705-G-2020-3254 Acute oral avian toxicity, Test guidelines Recommends an alternative testing option when regurgitation is observed in passerine studies. OPP EFED 3254
Guidance for Use When Regurgitation is Observed in Avian Acute Toxicity Studies with Passerine Species 2012-04-09 2020-02-28 EPA 705-G-2020-1379 Pesticide Science and Assessing Pesticide Risks Guidance based on comparison of results from the TG223 validation studies to results from avian acute oral studies previously submitted to EPA for two test chemicals following EPA's 850.2100 (public draft) guidelines. OPP EFED 1379
Hydrolysis of [test compound] at pH [4,7, and 9, or other values studied] 2012-05-01 2020-02-28 EPA 705-G-2020-3296 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3296
Label Review Manual (Chapter 8_Env Hazards) 2012-01-01 2020-02-28 EPA 705-G-2020-3262 Label statements This guidance provides the language informing users of the potential hazards to the environment from transport, use, storage, or spill of the product and indicates in what circumstances given statements are required. OPP EFED 3262
Laboratory Volatility of [test compound] 2012-12-01 2020-02-28 EPA 705-G-2020-3295 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3295
NAFTA Guidance Document for Conducting Terrestrial Field Dissipation Studies 2006-03-31 2020-02-28 EPA 705-G-2020-1404 Pesticide Science and Assessing Pesticide Risks Harmonized guidance for TFD studies that demonstrate transformation, transport and fate of pesticides under representative actual use conditions. Field studies substantiate physicochemical, mobility and biotransformation data from laboratory studies. OPP EFED 1404
OCSPP 850.3000: Background and Special Considerations- Tests with Terrestrial Beneficial Insects, Invertebrates and Microorganisms [EPA 712-C-020] 2012-01-01 2020-02-28 EPA 712-C-020 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 189
OCSPP 850.4000: Background and Special Considerations- Tests with Terrestrial and Aquatic Plants, Cyanobacteria, and Terrestrial Soil-Core Microcosms [EPA 712-C-013] 2012-01-01 2020-02-28 EPA 712-C-013 Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP EFED 196
Process for Requiring Exposure and Effects Testing for Assessing Risks to Bees during Registration and Registration Review 2016-01-01 2020-02-28 EPA 705-G-2020-3627 Pollinators, Honey Bees The intent of this document is to provide interim guidance to the public and staff within EPA OPP for determining when honey bee exposure and effects data identified in the EPA’s 2014 risk assessment framework Guidance for Assessing Pesticide Risks to Bees and the 2016 Guidance on Exposure and Effects Testing for Assessing Risks To Bees are required. OPP EFED 3627
Prospective Ground Water Monitoring of [test compound] 2012-12-01 2020-02-28 EPA 705-G-2020-3302 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3302
Reproductive Effects of {TAI or EUP} on Avian Species - [name of species] 2004-05-01 2020-02-28 EPA 705-G-2020-3313 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3313
Sample storage stability of [test compound(s)] in [frozen soil, water, etc.] 2012-12-01 2020-02-28 EPA 705-G-2020-3304 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3304
Soil Photolysis of [test compound] 2012-05-01 2020-02-28 EPA 705-G-2020-3298 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3298
SOP: Evaluation of Patent Assertion Claims of Greater Than Additive (GTA) Effects 2020-01-01 2020-02-28 EPA 705-G-2020-3288 Synergy, Patent claims Addresses risk estimate uncertainties associated with U.S. patent assertions of greater than additive effects in mixtures of pesticide active ingredients for controlling pests (often referred to as “synergy”). OPP EFED 3288
Toxicity of {TAI or EUP} to Fish Early Life-Stage 2004-05-01 2020-02-28 EPA 705-G-2020-3309 Study Template The following study template, in conjunction with the associated test guideline, has been developed by EPA to provide a consistent format for submission of test data to the Agency for review. OPP EFED 3309
Toxicity Testing and Ecological Risk Assessment Guidance for Benthic Invertebrates 2014-04-10 2020-02-28 EPA 705-G-2020-1384 Pesticide Science and Assessing Pesticide Risks Guidance for when to require whole sediment toxicity tests and how to integrate sediment toxicity tests results into EFED ecological risk assessments. OPP EFED 1384
Buoyant Force Calculations 2016-08-24 2020-02-28 EPA 705-G-2020-1279 Pesticide Worker Safety Find out how buoyant force calculations are used to determine if a secondary containment unit complies with the pesticide containment regulations. OPP FEAD 1279
Certification of Pesticide Applicators in Indian Country: Fact Sheet on Certification Options Available to Federally Recognized Tribes 2019-02-05 2020-02-28 EPA 705-G-2020-2531 Certification of Pesticide Applicators The purpose of this document is to inform federally recognized tribal governments and pesticide regulatory agencies of new requirements for tribal certified applicator plans and EPA’s intent to propose revisions to the EPA Plan for the Federal Certification of Applicators of Restricted Use Pesticides within Indian Country (i.e., EPA Plan) and associated options. OPP FEAD 2531
Clarification of PR Notice 2003-1 2015-06-11 2020-02-28 EPA 705-G-2020-1287 Pesticide Registration This document clarifies when and how the National Organic Program logo may be used on pesticide products and how to obtain approval to add it. OPP FEAD 1287
CPARD USER GUIDE: For State Lead Agency (SLA) and Tribal Representatives with Certification Plans (CPs) 2019-11-01 2020-02-28 EPA 705-G-2020-3686 Certification of Pesticide Applicators The Certification Plan and Reporting Database (CPARD) is a compilation of EPA?approved pesticide applicator certification plans and reporting as required by the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) and the federal Certification of Pesticide Applicators regulations at 40 CFR Part 171. In 2019, EPA added a section (Certification 2020) on the review and approval of modified certification plans due to EPA by March 4, 2020. This guide describes how to register and use CPARD. OPP FEAD 3686
Definition of Indian Country 2018-12-19 2020-02-28 EPA 705-G-2020-0959 Pesticide Applicator Certification in Indian Country Definition of Indian Country OPP FEAD 959
Detailed Comparison of the 2016 Revisions to the Existing Rule 2016-12-30 2020-02-28 EPA 705-G-2020-2913 Certification of Pesticide Applicators Comparison tables of the 2016 revisions to the Certification of Pesticide Applicator Rule to the existing rule. OPP FEAD 2913
Draft PRN 2006-A: Use of Antimicrobial Pesticide Products in Heating, Ventilation, Air Conditioning and Refrigeration Systems (HVAC&R) 2006-01-01 2020-02-28 EPA 705-G-2020-0972 Pesticide Registration This notice provides guidance to registrants of EPA-registered sanitizer, disinfectant and other antimicrobial products whose labels bear general directions for use on or incorporation within hard, non-porous or porous surfaces, but which are not specifically registered for treatment of Heating, Ventilation, Air Conditioning and Refrigeration Systems (HVAC&R also referred to as HVAC. Some labels currently use the term HVAC but for reference purposes of this PR Notice, HVAC&R will be used) OPP FEAD 972
Drift Reduction Technology Study Format 2017-01-01 2020-02-28 EPA 705-G-2020-1268 Reducing Pesticide Drift Generic Format for Wind Tunnel and Field Study Reports OPP FEAD 1268
EPA Pesticide Container and Repackaging Regulations - Flow Chart 1 2012-04-27 2020-02-28 EPA 705-G-2020-1292 Pesticide Worker Safety Flow Chart 1: Is this container a service container or a portable refillable container? OPP FEAD 1292
EPA Pesticide Container and Repackaging Regulations - Flow Chart 2 2012-04-27 2020-02-28 EPA 705-G-2020-1293 Pesticide Worker Safety A flowchart which diagrams the question "Can I fill this large portable refillable container (greater than 119 gallons)? OPP FEAD 1293
EPA Pesticide Container and Repackaging Regulations - Flow Chart 3 2012-04-27 2020-02-28 EPA 705-G-2020-1294 Pesticide Worker Safety Flow Chart 3: Can I fill this small portable refillable container OPP FEAD 1294
EPA-Verified and Rated Drift Reduction Technologies 2019-01-01 2020-02-28 EPA 705-G-2020-0907 Reducing Pesticide Drift EPA will review test reports and assign star ratings to drift reduction technologies. EPA-verified drift reduction technologies and their ratings will be added to this page as they become available. OPP FEAD 907
Exam Administration and Security Procedures Manual  2006-01-01 2020-02-28 EPA 705-G-2020-2408 pesticide applicator certification A guide developed by the Certification and Training Assessment Group for use by State, Tribal, and Territorial Pesticide Programs.  OPP FEAD 2408
Exporting Unregistered Pesticides: Foreign Purchaser Acknowledgement Statements 2020-01-01 2020-02-28 EPA 705-G-2020-3590 FIFRA Export Policy This website provides guidance to companies intending to export unregistered pesticides to promote compliance assistance with FIFRA Sec. 17(a) and related regulations at 40 CFR 168.75)   OPP FEAD 3590
Federal Agency Certification Plan Outline 2019-08-28 2020-02-28 EPA 705-G-2020-2528 Certification of Pesticide Applicators This document is intended to answer Federal agency questions on the 2017 Certification of Pesticide Applicators regulation. OPP FEAD 2528
Federal Certification Standards for Pesticide Applicators 2018-04-02 2020-02-28 EPA 705-G-2020-2991 Certification of Pesticide Applicators Information on the standards for applicators. OPP FEAD 2991
FIFRA Pesticides Export Policy Interpretative Guidance Issue: Multilingual Labeling 1993-04-08 2020-02-28 EPA 705-G-2020-2769 FIFRA Pesticides Export Policy This document addresses the requirement that certain labeling statements appear in English and in the languages of destination countries if known or reasonably ascertainable by the exporter.  OPP FEAD 2769
FIFRA Pesticides Export Policy: Questions & Answers 2019-05-21 2020-02-28 EPA 705-G-2020-2509 FIFRA exports questions and answers are intended to assist in compliance with the Environmental Protection Agency's February 18, 1993 rule (58 FR 9062) regarding the exportation of pesticides. OPP FEAD 2509
FIFRA Pesticides Export Policy: Questions & Answers Issue: Research and Development Pesticides; Active Ingredient Concentrations 2017-02-28 2020-02-28 EPA 705-G-2020-2510 FIFRA exports questions and answers are intended to assist in compliance with the Environmental Protection Agency's February 18, 1993 rule (58 FR 9062) regarding the exportation of pesticides. OPP FEAD 2510
Frequently Asked Questions on the Container and Containment Labeling Requirements 2019-08-27 2020-02-28 EPA 705-G-2020-1278 Pesticide Worker Safety Frequently Asked Questions on the Container and Containment Labeling Requirements OPP FEAD 1278
Generic Verification Protocol for Testing Pesticide Application Spray Drift Reduction Technologies for Row and Field Crops 2017-01-01 2020-02-28 EPA 705-G-2020-1361 Reducing Pesticide Drift This generic verification protocol provides a detailed method to conduct and report results from a verification test of pesticide application technologies that can be used to evaluate these technologies for their potential to reduce spray drift. OPP FEAD 1361
Guidance on Basic Elements of an EPA-Funded Tribal Pesticide Program 2017-03-25 2020-02-28 EPA 705-G-2020-1475 Pesticide Advisory Committees and Regulatory Partners This guidance document describes basic elements for an EPA-funded tribal pesticide program. OPP FEAD 1475
Guidance to Submit A Pesticide Petition 2018-03-01 2020-02-28 EPA 705-G-2020-3591 Pesticide Petition EPA offers a number of ways for the public to participate in and comment on regulatory actions that the agency proposes to take regarding the registration and review of pesticides. This webpage identifies those opportunities, including guidance on how to submit a pesticide petition.  OPP FEAD 3591
How to Get Certified as a Pesticide Applicator 2018-11-15 2020-02-28 EPA 705-G-2020-2990 Certification of Pesticide Applicators Information on what someone needs to do to get certified as a pesticide applicator. OPP FEAD 2990
Improving Labels to Reduce Pesticide Drift 2014-08-01 2020-02-28 EPA 705-G-2020-0903 Reducing Pesticide Drift We encourage pesticide manufacturers to state on their product labels that applicators should use DRT-rated technologies in applying pesticide products. The page includes information on how to obtain approval to add these instructions. OPP FEAD 903
Interim Policy for Repair of Pesticide Containers 2009-10-09 2020-02-28 EPA 705-G-2020-1280 Pesticide Worker Safety EPA will consider on a case-by-case basis whether to allow repair of minor damage to pesticide containers in the retail environment. Find out more about how EPA is implementing this policy. OPP FEAD 1280
NAFTA Guidance on Data Requirements for Pesticide Import Tolerances: Questions & Answers 2018-01-01 2020-02-28 EPA 705-G-2020-1476 Pesticide Tolerances These Q&A's provide details of implementation related to a guidance document describing the data requirements for establishing pesticide import tolerances in Canada and the United States: NAFTA Guidance on Data Requirements for Pesticide Import Tolerances. OPP FEAD 1476
Pesticide Container and Repackaging Standards 2015-06-01 2020-02-28 EPA 705-G-2020-2910 Container/Repackaging Scope of the Non-refillable Container, Refillable Container, and Repackaging Regulations for Pesticide Containers OPP FEAD 2910
Pesticide Containers 2019-12-03 2020-02-28 EPA 705-G-2020-1276 Pesticide Worker Safety The pesticide container regulations establish standards for pesticide containers, repackaging, label instructions and to ensure safe use, reuse and disposal and adequate cleaning of the containers. OPP FEAD 1276
Pesticide Containment Structures 2019-11-12 2020-02-28 EPA 705-G-2020-1282 Pesticide Worker Safety Learn about federal and state requirements for pesticide containment structures. OPP FEAD 1282
Pesticide Registration (PR) Notice 87-1 MOU 1987-01-01 2020-02-28 EPA 705-G-2020-1053 Pesticide Registration These documents provide more information related to implementation of Pesticide Registration Notice 87-1, which addresses label improvement for pesticides applied through irrigation systems. OPP FEAD 1053
Pesticide Worker Protection Standard “How to Comply” Manual 2016-09-30 2020-02-28 EPA 705-G-2020-1750 Pesticide Worker Safety The “How to Comply” manual provides information for employers on complying with the worker protection standard for agricultural workers. It has been updated to cover the 2015 revisions to the WPS. OPP FEAD 1750
PR (Pesticide Registration) Notice 96-8; Toxicologically Significant Levels of Pesticide Active Ingredients 1996-10-31 2020-02-28 PR Notice 96-8 Pesticide Registration Notices by Year This notice sets out EPA's interpretation of the term "toxicologically significant" as it applies to contaminants in pesticide products that are also pesticide active ingredients. This notice provides risk-based concentration levels of such contaminants that will generally be considered toxicologically significant. These concentrations are defined according to the type of pesticide that is contaminated and the pesticide category of the contaminant. OPP FEAD 27
PR Notice 2000-1; Applicability of the Treated Articles Exemption to Antimicrobial Pesticides 2000-03-06 2020-02-28 PR Notice 2000-1 Pesticide Registration Notices by Year This notice clarifies EPA policy with respect to the scope of the "treated articles exemption" in 40 CFR 152.25(a). This exemption covers qualifying treated articles and substances bearing claims to protect the article or substance itself. EPA does not regard this exemption as including articles or substances bearing implied or explicit public health claims against human pathogens. OPP FEAD 32
PR Notice 2000-5; Guidance for Mandatory and Advisory Labeling Statements 2000-05-10 2020-02-28 PR Notice 2000-5 Pesticide Registration Notices by Year This notice provides guidance to the registrant for improving the clarity of labeling statements in order to avoid confusing directions and precautions, and to prevent the misuse of pesticides.  OPP FEAD 33
PR Notice 2001-3; Insect Repellents: Labeling Restrictions for Use on Infants and Children and Restrictions on Food Fragrances and Colors 2001-01-16 2020-02-28 PR Notice 2001-3 Pesticide Registration Notices by Year This notice announces EPA's approach to insect repellents bearing claims for use specifically on infants and children. EPA believes that the label changes and policy clarification set forth in this PR Notice will reduce risks associated with the improper use of insect repellents and will improve consumer understanding. Additionally, this PR Notice states EPA's current position on insect repellents formulated to contain colors and fragrances predominantly associated with food (e.g., grape, watermelon, or orange).  OPP FEAD 34
PR Notice 2001-5; Guidance for Pesticide Registrants on Pesticide Resistance Management Labeling 2001-06-19 2020-02-28 PR Notice 2001-5 Pesticide Registration Notices by Year This archived PRN provided guidance for pesticide registrants on pesticide resistance management labeling that has since been superseded. OPP FEAD 35
PR Notice 2002-2; Guidance for Submitting Requests for Threshold of Regulation Decisions to OPP 2002-08-20 2020-02-28 PR Notice 2002-2 Pesticide Registration Notices by Year In the Federal Register of October 27, 1999 (64 FR 57881), the Environmental Protection Agency (EPA) announced the availability of a document entitled “Threshold of Regulation Policy - Deciding Whether a Pesticide with a Food Use Pattern Needs a Tolerance.” The Threshold of Regulation (TOR) Policy describes criteria and procedures to be considered in determining whether a use of a pesticide in a location and manner that has the possibility of resulting in residues in food is below the threshold of regulation. OPP FEAD 36
PR Notice 2003-1; Labeling of Pesticide Products under the National Organic Program 2003-01-31 2020-02-28 PR Notice 2003-1 Pesticide Registration Notices by Year This notice describes how registrants can obtain EPA approval of label language indicating that all ingredients (active and inert) in a pesticide product and all uses of that pesticide meet the criteria defined in the United States Department of Agriculture’s National Organic Program Rule. This Pesticide Registration Notice provides an example of acceptable label language and the procedures for adding such identification to product labels. The information on the pesticide label will assist organic growers and those persons certifying organic production methods in knowing which pesticide products meet the requirements of the NOP Rule for use in organic agriculture.  OPP FEAD 37
PR Notice 2007-2: Guidance on Small-Scale Field Testing and Low-level Presence in Food of Plant-Incorporated Protectants (PIPs 2007-04-30 2020-02-28 PR Notice 2007-2 Pesticide Registration Notices by Year This PR Notice provides clarification on the process by which EPA reviews and ensures the safety of residues of plant-incorporated protectants (PIPs) potentially present at low levels in food or feed, and the conditions under which a tolerance or exemption from the requirement of a tolerance would be required for field tests for biotechnology-derived food and feed crop plants containing plant-incorporated protectants. OPP FEAD 38
PR Notice 83-3 Appendix B 1983-01-01 2020-02-28 EPA 705-G-2020-1059 Pesticide Registration This appendix to PR Notice 83-3 lists pesticides that are hazardous waste under 40 CFR 261, 33(e) and (f) when discarded. OPP FEAD 1059
PR Notice 94-4 MOU on Regulation of Liquid Chemical Germicides Intended for Use on Medical Devices 1994-01-01 2020-02-28 EPA 705-G-2020-1039 Pesticide Registration This MOU between EPA and FDA establishes roles for regulation of liquid chemical germicides intended for use on medical devices. An amendment revises the disclaimer statement for labels of all liquid chemical germicides, other than FDA-approved sterilants. OPP FEAD 1039
PR Notice 97-5; Use of Common Names for Active Ingredients on Pesticide Labeling 1997-09-11 2020-02-28 PR Notice 97-5 Pesticide Registration Notices by Year This notice announces EPA policy to expand the use of common names on pesticide labeling. EPA will permit the use of common names approved by the American National Standards Institute (ANSI) in the label ingredients statement without the accompanying scientific chemical names, and will permit the use of other common names listed in this notice without the accompanying scientific chemical name. EPA also recommends the inclusion on labels of Chemical Abstracts Service (CAS) numbers to identify ingredients definitively. OPP FEAD 28
PR Notice 97-6; Use of Term "Inert" in the Label Ingredients Statement 1997-09-11 2020-02-28 PR Notice 97-6 Pesticide Registration Notices by Year This notice announces a change in EPA policy regarding the label ingredients statement. Effective immediately, the phrase "Inert ingredients," may be replaced by the term "Other ingredients." Although no registrant is required to make this change, EPA encourages registrants to do so. Provided the term "Other ingredients" is used, the change may be made at any time without notification to the Agency. OPP FEAD 29
PR Notice 98-1; Self-Certification of Product Chemistry Data 1998-01-12 2020-02-28 PR Notice 98-1 Pesticide Registration Notices by Year The Office of Pesticide Programs has established a self-certification program for certain product chemistry data of manufacturing-use products and end-use products produced by a non-integrated formulation system. This program is voluntary and is intended to simplify and accelerate the processing of applications for registration and reregistration while maintaining protection of public health and the environment. To be eligible for self-certification, a product must be formulated from registered source(s). OPP FEAD 30
PR Notice 99-1; Import of Unregistered Pesticides Intended for Export 1999-03-01 2020-02-28 PR Notice 99-1 Pesticide Registration Notices by Year This Pesticide Registration (PR) notice clarifies EPA's interpretation of the scope of the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) Section 17 (a)(1), as it relates to the import of unregistered pesticides, devices or active ingredients used in producing a pesticide when the importation is solely for the purpose of formulation or packaging for subsequent export. OPP FEAD 31
PRN  1997-01-01 2020-02-28 EPA 705-G-2020-0997 Pesticide Registration This is a list of common names for use on pesticide Labels approved by The American National Standards Institute. OPP FEAD 997
PRN 1982-2 Change in Procedures for Approval of Applications 1982-06-18 2020-02-28 EPA 705-G-2020-1506 Pesticide Registration This Notice revises EPA procedures with respect to submission of final printed labeling and agreement to conditions of registration. OPP FEAD 1506
PRN 2000-10: Changes to "Effective Date and Procedures", "Applicability of the Treated Articles Exemption to Antimicrobial Pesticides" 2000-01-01 2020-02-28 EPA 705-G-2020-0634 Pesticide Registration This PR notice addresses the compliance date and other issues related to PR Notice 2000-1, Applicability of the Treated Articles Exemption to Antimicrobial Pesticides. OPP FEAD 634
PRN 2000-2: The FIFRA Endangered Species Task Force 2002-01-01 2020-02-28 EPA 705-G-2020-0655 Pesticide Registration This PR Notice announces an industry-wide Task Force that has been formed in response to EPA data requirements related to the potential impact of pesticides on threatened and endangered species. OPP FEAD 655
PRN 2000-6; Minimum Risk Pesticides Exempted under FIFRA Section 25(b) Clarification of Issues 2000-01-01 2020-02-28 EPA 705-G-2020-2672 Pesticide Registration Minimum Risk Pesticides Exempted under FIFRA Section 25(b) Clarification of Issues Web information posted in January 2015: Minimum Risk Pesticides Exempted from FIFRA Registration supersedes this PR notice OPP FEAD 2672
PRN 2000-7: Non-Dietary Exposure Task Force 2000-01-01 2020-02-28 EPA 705-G-2020-0636 Pesticide Registration This PR Notice announces an industry-wide task force to jointly develop residential indoor exposure data for pesticides containing one or more of the active ingredients synthetic pyrethroids, pyrethrum and synergists. OPP FEAD 636
PRN 2000-8: Reportability of Attorneys’ Opinions and Conclusions Under 40 CFR Part 159 and FIFRA Section 6(a)(2) 2000-01-01 2020-02-28 EPA 705-G-2020-0635 Pesticide Registration EPA is issuing this pesticide registration notice to inform registrants of EPA’s opinion that an attorney’s professional legal judgment is not an opinion or conclusion that is reportable under 40 CFR part 159. OPP FEAD 635
PRN 2001-1: First Aid Statements on Pesticide Product Labels 2001-01-01 2020-02-28 EPA 705-G-2020-0633 Pesticide Registration This PR notice is intended to provide guidance for what the Agency believes is the most updated appropriate first aid language for pesticide product labels to ensure that they continue to adequately protect the public. OPP FEAD 633
PRN 2001-2: Acute Toxicity Data Requirements For Granular Pesticide Products, Including Those With Granular Fertilizers in the Product. 2001-01-01 2020-02-28 EPA 705-G-2020-0632 Pesticide Registration This PR Notice announces guidance intended to streamline the acute toxicity review and classification process for certain granular pesticide products, including those products that contain granular fertilizers. OPP FEAD 632
PRN 2001-4: Elimination of Phenol Resistance Testing for Antimicrobial Disinfectant and Sanitizer Pesticides 2001-01-01 2020-02-28 EPA 705-G-2020-0630 Pesticide Registration This Pesticide Registration notice announces the discontinuation of phenol resistance testing as a part of efficacy testing for antimicrobial disinfectants and sanitizers. OPP FEAD 630
PRN 2002-1: Lists of Pests of Significant Public Health Importance 2002-01-01 2020-02-28 EPA 705-G-2020-0628 Pesticide Registration This notice identifies pests of significant public health importance. This list does not, by itself, determine whether a pesticide product might be considered a "public health pesticide“ as that term is used in FIFRA. See Appendix A for the list. OPP FEAD 628
PRN 2003-3: Procedural Guidance for EPA's Office of Pesticide Programs Procedures Concerning the Development, Modification, and Implementation of Policy Guidance Documents 2003-01-01 2020-02-28 EPA 705-G-2020-0625 Pesticide Registration EPA’s Office of Pesticide Programs (OPP) will use the procedures in this document for developing, modifying, and implementing its pesticide program policy guidance documents. OPP FEAD 625
PRN 2005-1: Labeling Statements on Products Used for Adult Mosquito Control 2005-04-15 2020-02-28 EPA 705-G-2020-0624 Pesticide Registration This Notice presents the Agency’s guidance on appropriate label language for pesticide products intended for wide-area application to control adult mosquitoes. OPP FEAD 624
PRN 2007-1: Disposal Instructions on Non-Antimicrobial Residential or Household Use Pesticide Product Labels 2007-01-01 2020-02-28 EPA 705-G-2020-0970 Pesticide Registration This notice is being issued to update and revise PR Notice 2001-6 to clarify that the use of a toll-free number in the disposal instructions on non-antimicrobial residential or household use pesticide product labels is optional. If registrants choose to change or remove a toll-free number from the disposal instructions on their label, this notice provides guidance on making such changes. This notice supersedes PR Notice 2001-6. in its entirety and PR Notices 83-3 and 84-1 in part. See unit VI. OPP FEAD 970
PRN 2007-3: The Agricultural Handlers Exposure Task Force, L.L.C 2007-09-20 2020-02-28 EPA 705-G-2020-0962 Pesticide Registration This PR Notice discusses the Agricultural Handlers Exposure Task Force, an industry-wide task force formed to develop mixer, loader, and applicator exposure data for pesticides used in agricultural settings. It includes contacts for more information. OPP FEAD 962
PRN 2007-4: Labeling Revisions Required by the Final Rule “Pesticide Management and Disposal; Standards for Pesticide Containers and Containment 2008-04-29 2020-02-28 EPA 705-G-2020-0622 Pesticide Registration This notice provides instructions for implementing the new pesticide product label language required by the new regulations in 40 CFR part 156 established by the Final Rule “Pesticide Management and Disposal; Standards for Pesticide Containers and Containment” (71 FR 47330, August 16, 2006). This notice provides guidance to pesticide registrants on revising their product labels in order to implement the new requirements. Most registrants may be able to make the necessary label amendments by notification; however, in some cases an application for amendment and EPA approval may be required. As specified in the final rule, by August 17, 2009, all pesticide products distributed or sold by a registrant must have labels that comply with the new requirements (40 CFR § 156.159). OPP FEAD 622
PRN 2008-1: Notice to Manufacturers, Producers, Formulators, and Registrants of Pesticide Products 2008-05-01 2020-02-28 EPA 705-G-2020-0961 Pesticide Registration This Notice presents EPA's guidance on optional environmental hazard label language for certain non-restricted use pesticide products intended for outdoor residential use. It clarifies language on how the user can avoid environmental contamination. OPP FEAD 961
PRN 2008-2: Antimicrobial Pesticide Products With Anthrax-Related Claims 2008-08-26 2020-02-28 EPA 705-G-2020-0960 Pesticide Registration This notice provides guidance to prospective applicants of antimicrobial products that make labeling claims to “inactivate Bacillus anthracis (anthrax) spores” (hereafter referred to as “anthrax-related products”). This guidance should help the United States be prepared to respond to incidents involving anthrax spores by assuring that anthrax-related products are registered, that they bear appropriate labeling, and that they are effective when used as directed. In addition, this guidance will help protect public health from the potential risks of anthrax spores by employing terms and conditions of registration that limit the use of anthrax-related products to those who are properly trained and determined to be competent in their use. OPP FEAD 960
PRN 2009-1: Establishment of Antimicrobial Exposure Assessment Task Force II 2009-09-30 2020-02-28 EPA 705-G-2020-0621 Pesticide Registration This PR notice announces the establishment of the Antimicrobial Exposure Assessment Task Force II, an industry-wide task force to develop mixer, loader, applicator and post-application exposure data for antimicrobial pesticides used in various settings. OPP FEAD 621
PRN 2010-X; Draft; Proposed Guidance on False or Misleading Pesticide Product Brand Names 2010-01-01 2020-02-28 EPA 705-G-2020-2662 Draft; PRN; Draft PRN; PRN 2010-x; 2010 Proposed Guidance on False or Misleading Pesticide Product Brand Names. OPP FEAD 2662
PRN 2011-1: Residential Exposure Joint Venture 2011-01-03 2020-02-28 EPA 705-G-2020-0620 Pesticide Registration This PR Notice is to advise registrants of an industry-wide joint venture, titled the Residential Exposure Joint Venture (REJV), which has developed a national survey regarding residential consumer use/usage data for pesticides. OPP FEAD 620
PRN 2011-2: Non-Dietary Exposure Task Force 2011-11-23 2020-02-28 EPA 705-G-2020-0619 Pesticide Registration This PR Notice includes information about an industry-wide task force, the Non-Dietary Exposure Task Force (NDEFT), including how registrants can participate or use data developed by the task force. OPP FEAD 619
PRN 2011-3: Standard Format for Data Submitted Under FIFRA and Certain Provisions of FFDCA 2011-11-30 2020-02-28 EPA 705-G-2020-0618 Pesticide Registration This PR Notice updates and replaces Pesticide Registration Notice 86-5 and discusses both the recommended and the required procedures for submitting FIFRA and FFDCA data. OPP FEAD 618
PRN 2012-1: Material Safety Data Sheets as Pesticide Labeling 2012-01-01 2020-02-28 EPA 705-G-2020-0617 Pesticide Registration This Notice updates and clarifies EPA’s determination in PRN 92-4 that a Material Safety Data Sheet that accompanies a pesticide product is considered part of the pesticide’s labeling but does not need EPA approval if it is consistent with 40CFR Part 156. OPP FEAD 617
PRN 2012-X; Draft; Guidance for Antimicrobial Pesticide Products with Mold-Related Label Claims. Docket ID EPA-HQ-OPP-2010-0539 2012-12-12 2020-02-28 EPA 705-G-2020-2661 Pesticide Registration Guidance for Antimicrobial Pesticide Products with Mold-Related Label Claims. Docket ID EPA-HQ-OPP-2010-0539 OPP FEAD 2661
PRN 2013-1: Silver Task Force North America 2013-05-01 2020-02-28 EPA 705-G-2020-0616 Pesticide Registration This PR Notice announces the establishment of the Silver Task Force North America (STFNA), which was created to jointly develop data to support registration review. OPP FEAD 616
PRN 2013-2: Peroxy Compounds Task Force 2013-11-13 2020-02-28 EPA 705-G-2020-0615 Pesticide Registration This PR Notice announces the establishment of the Peroxy Compounds Task Force (PCTF). The PCTF is open to all registrants and applicants with products containing peroxy compounds created to jointly develop data to support registration review under FIFRA. OPP FEAD 615
PRN 2017-1 Guidance for Pesticide Registrants on Pesticide Resistance Management Labeling 2017-08-24 2020-02-28 PRN 2017-1 PRN; Guidance; PRN 2017-1; 2017-1 PRN 2017-1, Guidance for Pesticide Registrants on Pesticide Resistance Management Labeling, revises and updates PRN 2001-5. PRN 2017-1 applies to all conventional, agricultural pesticides (i.e., herbicides, fungicides, bactericides, insecticides, and acaricides). OPP FEAD 2657
PRN 2017-2: Guidance for Herbicide-Resistance Management, Labeling, Education, Training, and Stewardship 2017-01-01 2020-02-28 EPA 705-G-2020-1711 Pesticide Registration Provides 11 elements focused on labeling, education, training and stewardship strategies. OPP FEAD 1711
PRN 2018-1 Pesticides: Guidance for Registrants on the Determination of Minor Use  2018-03-22 2020-02-28 PRN 2018-1 PRN 2018-1; Pesticide Registration Notice; OPP; OCSPP This PRN describes the revised approach to interpreting economic minor use based on the concept of the registration of a pesticide as an investment.  OPP FEAD 2655
PRN 66 Federal Registration of Economic Poisons 1966-11-16 2020-02-28 EPA 705-G-2020-1425 Pesticide Registration The Federal Insecticide, Fungicide, and Rodenticide Act, and the regulations promulgated thereunder, provide that an economic poison is misbranded if its labeling bears any statement, graphic representation, or design which is false or misleading. OPP FEAD 1425
PRN 67-5 Economic Poisons Containing Sodium Hypochlorite 1967-09-26 2020-02-28 EPA 705-G-2020-1424 Pesticide Registration Products containing sodium hypochlorite at various concentrations have been accepted for registration under the Federal Insecticide, Fungicide, and Rodenticide Act. OPP FEAD 1424
PRN 70-16: Requirements for Additional Labeling on Products Containing Sodium Hypochlorite 1970-01-01 2020-02-28 EPA 705-G-2020-0697 Pesticide Registration This PR Notice describes additional labeling for pesticide products containing sodium hypochlorite, due to the rapid degradation of the products, to ensure that product effectiveness is maintained. OPP FEAD 697
PRN 72-6; Changes in standard for expressing potency of products containing Bacillus Truringiensis Berliner 1972-01-01 2020-02-28 EPA 705-G-2020-2671 EPA Archive Changes in standard for expressing potency of products containing Bacillus Truringiensis Berliner OPP FEAD 2671
PRN 73-4: Residual Insecticides in Food Handling Establishments 1973-07-06 2020-02-28 EPA 705-G-2020-0696 Pesticide Registration This notice provides a copy of a Federal Register notice published July 6, 1973, regarding certain insecticides used in food-handling establishments. It establishes certain definitions and requirements related to approval for crack and crevice treatment. OPP FEAD 696
PRN 75-5: Unacceptable Use of the Word "Chlorine" in the Name and Labeling of Pesticides 1975-01-01 2020-02-28 EPA 705-G-2020-1423 Pesticide Registration Use of the word "Chlorine" on labels other than in products containing liquefied chlorine under pressure has been determined to be in violation of Section 2(q)(l)(A) of the Federal Insecticide, Fungicide, and Rodenticide Act. OPP FEAD 1423
PRN 80-2: Label Improvement Program: Deletion of Salt Water Emesis Statements 1980-01-01 2020-02-28 EPA 705-G-2020-0695 Pesticide Registration As of 1980, pesticide registrants had to remove salt-water emesis statements from product labels. OPP FEAD 695
PRN 81-3; Label Improvement Program: Change in Test Methods for and Categorization of Eye Irritation 1981-01-01 2020-02-28 EPA 705-G-2020-2670 PRN Label Improvement Program: Change in Test Methods for and Categorization of Eye Irritation OPP FEAD 2670
PRN 81-4: Label Improvement Program - Label Revisions to Accommodate New AOAC Methods of Chemical Analysis 1981-01-01 2020-02-28 EPA 705-G-2020-0694 Pesticide Registration This notice describes procedures EPA will use to ensure that pesticide label ingredient statements reflect percentages of ingredients determined by the most specific analytical techniques approved by the Association of Official Analytical Chemists (AOCA). OPP FEAD 694
PRN 82-1: Revised Policy on Label Claims for Tank Mixing 1982-01-01 2020-02-28 EPA 705-G-2020-1061 Pesticide Registration This notice sets out EPA's policy related to claims for tank mixing a pesticide product with another pesticide product. OPP FEAD 1061
PRN 83-3: Label Improvement Program - Storage and Disposal Label Statements 1983-01-01 2020-02-28 EPA 705-G-2020-1058 Pesticide Registration This Notice is to inform all registrants that the label of all pesticide products must include updated storage and disposal statements. No application for amended registration is required if you use the exact wording contained in this Notice. OPP FEAD 1058
PRN 84-1: Clarification of Label Improvement Program for Farmworker Safety and Pesticide Storage and Disposal Instructions 1984-01-01 2020-02-28 EPA 705-G-2020-1054 Pesticide Registration This PR notice clarifies EPA's intentions regarding the Pesticide Label Improvement Program for Farmworker Safety (PR Notice 83-2) and Pesticide Storage and Disposal Instructions (PR Notice 83-3) issued on March 26, 1983. OPP FEAD 1054
PRN 84-5: Label Improvement Program for Fumigants 1984-01-01 2020-02-28 EPA 705-G-2020-0693 Pesticide Registration This notice required registrants of fumigant products to revise the labeling of products registered under FIFRA section 3 or 24(c) to include additional precautionary statements and other statements described in the notice. OPP FEAD 693
PRN 85-6: Clarification of Label Improvement Program for Fumigants. Revision of PR Notice 84-5 1985-01-01 2020-02-28 EPA 705-G-2020-0692 Pesticide Registration This Pesticide Registration Notice revises and clarifies PR Notice 84-5, related to label changes for fumigant products. OPP FEAD 692
PRN 87-1: Label Improvement Program for Pesticides Applied through Irrigation Systems (Chemigation) 1987-01-01 2020-02-28 EPA 705-G-2020-1048 Pesticide Registration This Notice requires registrants of pesticide products registered under FIFRA and applied through irrigation systems to revise the labeling for such products to include additional use directions and other statements described in this Notice. OPP FEAD 1048
PRN 87-6: Inert Ingredients in Pesticide Products; Policy Statement 1987-01-01 2020-02-28 EPA 705-G-2020-1047 Pesticide Registration This PR notice announces certain policies regarding inert ingredients in pesticide products, including amendments required for products containing inert ingredients of toxicological concern. OPP FEAD 1047
PRN 88-2: Clustering of Quaternary Ammonium Compounds 1988-02-26 2020-02-28 EPA 705-G-2020-1420 Pesticide Registration This Notice announces that EPA has clustered the Quaternary Ammonium Compounds into four groups for the purpose of testing chemicals to build a database that will support continued registration of the entire family of quaternary ammonium compounds OPP FEAD 1420
PRN 88-6: Change in Registration Procedures; Agency Approval not Required for Certain Amendments 1988-01-01 2020-02-28 EPA 705-G-2020-0691 Pesticide Registration This notice describes certain modifications to pesticide registrations that no longer require an application to or approval by EPA, based on amendments to 40 CFR 152.44 in May 1988. OPP FEAD 691
PRN 90-1: Inert Ingredients in Pesticide Products; Revised Policy Statement 1990-01-01 2020-02-28 EPA 705-G-2020-1045 Pesticide Registration This notice discusses compliance with Federal Register Notice (54 FR 58314; November 22, 1989). OPP FEAD 1045
PRN 90-3: Announcing the Formation of an Industry-Wide Spray Drift Task Force 1990-01-01 2020-02-28 EPA 705-G-2020-1044 Pesticide Registration "A Spray Drift Task Force has been organized pursuant to provisions of FIFRA section 3 (c)(2)(B)(ii) to share the cost of developing a generic spray drift data base capable of satisfying spray drift data requirements for pesticide product registrations. OPP FEAD 1044
PRN 91-1: Procedures for Voluntarily Requesting Deletion of Approved Uses from Registered Labels 1991-01-01 2020-02-28 EPA 705-G-2020-1042 Pesticide Registration This pesticide registration notice defines procedures for registrants to use when they want to request an amendment to delete one or more uses from an approved registration, and it summarizes the actions the Agency will take in response to such requests. OPP FEAD 1042
PRN 91-2: Accuracy of Stated Percentages for Ingredients Statement 1991-01-01 2020-02-28 EPA 705-G-2020-1043 Pesticide Registration The purpose of this notice is to clarify the Office of Pesticide Program's policy with respect to the statement of percentages in a pesticide's label's ingredient statement. OPP FEAD 1043
PRN 92-1: Requirement to submit and identify adverse effects information 1992-01-01 2020-02-28 EPA 705-G-2020-0687 Pesticide Registration This notice clarifies the Office of Pesticide Program's policy with regard to submission and identification of adverse effects information under FIFRA Section 6(a)(2). OPP FEAD 687
PRN 92-2: Permissible label claims regarding ozone depleting substances 1992-01-01 2020-02-28 EPA 705-G-2020-0688 Pesticide Registration This notice describes EPA's policy for certain chlorofluorocarbon-related labeling claims on pesticide aerosol products. Under this policy, true claims that a product does not contain CFCs or other ozone-depleting substances are permitted on labels. OPP FEAD 688
PRN 92-4: Material Safety Data Sheets as Pesticide Labeling 1992-01-01 2020-02-28 EPA 705-G-2020-0689 Pesticide Registration This notice describes EPA's interpretation that a material safety data sheet may accompany a pesticide or device without approval from EPA as long as it does not conflict with the approved pesticide labeling. OPP FEAD 689
PRN 93-1: Statement of Restricted Use Classification 1993-01-01 2020-02-28 EPA 705-G-2020-0668 Pesticide Registration This notice explains EPA's policy on the content and placement of the statement required on the front panel of labeling of pesticides classified for restricted use (RU). OPP FEAD 668
PRN 93-10: Effluent Discharge Labeling Statements 1993-01-01 2020-02-28 EPA 705-G-2020-0682 Pesticide Registration This notice describes revised effluent discharge labeling statements required on all manufacturing use products and end use products that may be discharged to waters of the United States or municipal sewer systems. OPP FEAD 682
PRN 93-11: Supplemental Guidance for PR Notice 93-7 - Labeling Revisions Required by the WPS 1993-01-01 2020-02-28 EPA 705-G-2020-0684 Pesticide Registration This pesticide registration notice augments the guidance provided by PR notice 97-3 to provide options that you may choose to allow efficient production and distribution of products that comply with PR Notice 93-7. OPP FEAD 684
PRN 93-2: Waiver of Crop Field Trial Data for Aerial Applications 1993-01-01 2020-02-28 EPA 705-G-2020-0673 Pesticide Registration This notice is to inform all pesticide registrants that the requirement for crop field trials reflecting aerial applications may be waived under certain circumstances provided adequate data are available on the same crop with use of ground equipment. OPP FEAD 673
PRN 93-3: Labeling Statement Prohibiting Application to Water 1993-01-01 2020-02-28 EPA 705-G-2020-0674 Pesticide Registration This notice explaining the policy on label statement prohibiting pesticide application to water pertains only to the labeling statement on pesticide products. It does not address the term "wetlands" as defined with respect to the Clean Water Act. OPP FEAD 674
PRN 93-4: Ban on Aerosol Products Containing CFCs and HCFCs under the Clean Air Act 1994-01-01 2020-02-28 EPA 705-G-2020-0675 Pesticide Registration This notice alerts pesticide registrants to a rule under the Clean Air Act banning distribution and sale of aerosol and pressurized products, including pesticide products, that contain chlorofluorocarbons (CFCs). OPP FEAD 675
PRN 93-5: Labeling Requirements of the Clean Air Act 1993-01-01 2020-02-28 EPA 705-G-2020-0676 Pesticide Registration A regulation under the Clean Air Act requires a warning statement on products (including pesticide products) manufactured with or containing Class I ozone-depleting substances, including chlorofluorocarbons, methyl chloroform and carbon tetrachloride. OPP FEAD 676
PRN 93-6: False or Misleading Statements Related to Efficacy; Revision of PR Notice 91-7 1993-01-01 2020-02-28 EPA 705-G-2020-0677 Pesticide Registration This notice clarifies EPA's policy with respect to certain claims of heightened efficacy for pesticide products and supersedes PR Notice 91-7. OPP FEAD 677
PRN 93-7: Labeling Revisions Required by the Worker Protection Standard (WPS) 1993-01-01 2020-02-28 EPA 705-G-2020-0678 Pesticide Registration The Worker Protection Standard (WPS) for agricultural pesticides, issued in August 1992, requires labeling changes for many pesticide end-use products. See guidance to determine what products are affected. OPP FEAD 678
PRN 93-8: Labeling Statement Prohibiting Application to Water; Amendment to PR Notice 93-3 1993-01-01 2020-02-28 EPA 705-G-2020-0680 Pesticide Registration This notice adds one paragraph to P.R. Notice 93-3, which requested registrants to amend product labeling to include a new labeling statement prohibiting application of a pesticide to water for certain products. OPP FEAD 680
PRN 93-9: Voluntary Reduced-Risk Pesticides Initiative 1993-01-01 2020-02-28 EPA 705-G-2020-0681 Pesticide Registration This PR Notice provides guidance on EPA's voluntary, interim process for identifying pesticides which may be eligible for priority treatment as lower risk products (1993). OPP FEAD 681
PRN 94-1: Withdrawal of PR Notice 91-8 1994-01-01 2020-02-28 EPA 705-G-2020-1041 Pesticide Registration EPA withdrew PR Notice 91-8, entitled "Revised Policy To Provide Applicants Other Than Basic Manufacturers An Opportunity To Submit Generic Data and Receive Data Compensation For It." OPP FEAD 1041
PRN 94-2: Recycling Empty Aerosol Pesticide Containers 1994-01-01 2020-02-28 EPA 705-G-2020-1040 Pesticide Registration This notice offers registrants use of an optional label statement permitting recycling as an alternative to instructions to dispose of aerosol pesticide containers. Registrants may add a label reference to recycling the empty aerosol pesticide container. OPP FEAD 1040
PRN 94-5: Requests for Re-considerations of Carcinogenicity Peer Review Decisions Based on Changes in Pathology Diagnoses 1994-01-01 2020-02-28 EPA 705-G-2020-1036 Pesticide Registration This notice sets forth a procedure to be followed for submission of pathology re-reads to the Agency. OPP FEAD 1036
PRN 94-6: Pesticide Products Registered for Use on Humans to Control Lice (Pediculicides) 1994-01-01 2020-02-28 EPA 705-G-2020-1034 Pesticide Registration This notice alerts pesticide registrants to a rule issued by Food and Drug Administration (FDA) under the Federal Food, Drug and Cosmetic Act (FFDCA) establishing conditions for safe and effective use of pediculicide drug products. OPP FEAD 1034
PRN 94-7: Label Improvement Program for the Revision of Use Directions for Commensal Rodenticides and Statement of the Agency's Policies on the Use of Rodenticide Bait Stations 1994-01-01 2020-02-28 EPA 705-G-2020-1032 Pesticide Registration This Notice requires registrants of certain pesticide products claimed to control commensal rodents and registered under FIFRA to revise the labeling of such products to bear certain statements concerning "tamper-resistant bait stations." OPP FEAD 1032
PRN 94-8: Water Soluble Packaging (WSP) 1994-01-01 2020-02-28 EPA 705-G-2020-1031 Pesticide Registration This notice describes the registration requirements for pesticide products containing water soluble packaging (WSP). OPP FEAD 1031
PRN 94-9: Announcing the Formation of Two Industry-Wide Task Forces: Agricultural Reentry Task Force and Outdoor Residential Exposure Task Force 1994-01-01 2020-02-28 EPA 705-G-2020-1030 Pesticide Registration This Notice announces two industry-wide Task Forces being formed in response to generic exposure data requirements. It contains EPA's policy on a registrant's options for, and responsibilities when joining Task Force as a way to satisfy data requirements. OPP FEAD 1030
PRN 95-1: Effluent Discharge Labeling Statements 1995-01-01 2020-02-28 EPA 705-G-2020-1029 Pesticide Registration This notice exempts certain pesticide products from bearing effluent discharge labeling statements specified by P.R. Notice 93-10 for manufacturing use products and end use products that may be discharged to waters of the U.S. or municipal sewer systems. OPP FEAD 1029
PRN 95-3: Reduction of Worker protection Standard (WPS) Interim Restricted Entry Intervals (REIS) for Certain Low Risk Pesticides 1995-05-03 2020-02-28 EPA 705-G-2020-1028 Pesticide Registration On January 11, 1995, EPA published a draft policy on "Reduced Restricted Entry Intervals for Certain Pesticides," in the Federal Register. The final policy was published in the Federal Register on May 3, 1995. This Notice contains the final policy. OPP FEAD 1028
PRN 95-5: Labeling Revisions Required By The Worker Protection Standard (WPS) For Sale Or Distribution Of Certain Agricultural Pesticides After October 23,1995 1995-01-01 2020-02-28 EPA 705-G-2020-1027 Pesticide Registration This notice provides guidance to people who sell or distribute pesticides on meeting requirements for labeling under the worker protection standard (1992 version). OPP FEAD 1027
PRN 96-1: Tolerance Enforcement Methods - Independent Laboratory Validation by Petitioner 1996-01-01 2020-02-28 EPA 705-G-2020-1026 Pesticide Registration This notice is intended to clarify the requirements for submission of an Independent Laboratory Validation to accompany new pesticide analytical methods and does not contain additional data requirements. This notice supersedes PR Notice 88-5. OPP FEAD 1026
PRN 96-2: Changes to Child-Resistant Packaging (CRP) Testing Requirements 1996-01-01 2020-02-28 EPA 705-G-2020-1025 Pesticide Registration This pesticide registration notice announced revisions to the effectiveness standards applicable to child-resistant packaging (CRP). OPP FEAD 1025
PRN 96-3: Pesticide Products Used to Disinsect Aircraft 1996-01-01 2020-02-28 EPA 705-G-2020-1024 Pesticide Registration This Notice specifies labeling changes for any pesticide product (insecticide) used for disinsecting aircraft. EPA required these changes based on incident information associated with the use of insecticide spray products occupied aircraft cabins. OPP FEAD 1024
PRN 96-4: Label Statements Involving Product Efficacy and Potential for Harm to Property 1996-01-01 2020-02-28 EPA 705-G-2020-1023 Pesticide Registration This notice explains EPA procedures in approving pesticide labels that include claims relating to the efficacy of agricultural pesticides and provides a warning to growers regarding reliance on label statements regarding pesticide efficacy. OPP FEAD 1023
PRN 96-7: Termiticide Labeling 1996-01-01 2020-02-28 EPA 705-G-2020-1021 Pesticide Registration This notice sets forth the Agency's policy with respect to certain labeling statements and minimum product performance (5 year period) for soil treatment termiticide products. OPP FEAD 1021
PRN 97-1: Agency Actions under the Requirements of the Food Quality Protection Act 1997-01-01 2020-02-28 EPA 705-G-2020-1018 Pesticide Registration This pesticide registration notice describes EPA's implementation of the Food Quality Protection Act, including the risk cup and risk management strategies under the new safety standard. OPP FEAD 1018
PRN 97-3: Guidelines for Expedited Review of Conventional Pesticides under the Reduced-Risk Initiative and for Biological Pesticides 1997-01-01 2020-02-28 EPA 705-G-2020-1017 Pesticide Registration EPA encourages the development, registration and use of lower-risk pesticide products which would result in reduced risks to human health and the environment. This Pesticide Registration notice and the related web page explain the process and criteria. OPP FEAD 1017
PRN 97-4: Consumer Access Numbers on Pesticide Labels 1997-01-01 2020-02-28 EPA 705-G-2020-1015 Pesticide Registration This notice describes EPA policy on including telephone numbers and other access numbers or internet addresses, on pesticide product labeling. It also explains how the telephone number of the National Pesticide Information Center hotline may be used. OPP FEAD 1015
PRN 97-5 Appendix B 1997-01-01 2020-02-28 EPA 705-G-2020-0999 Pesticide Registration Appendix B lists other names, not established by ANSI, which may also be used alone in the ingredients statement without an accompanying chemical name. OPP FEAD 999
PRN 97-7: Existing Stocks for Labeling Changes in PR Notices 1997-01-01 2020-02-28 EPA 705-G-2020-0992 Pesticide Registration EPA intends to establish October 1 as the annual compliance date for most EPA-initiated label changes specified by a PR Notice, FR Notice or similar mechanism. We will allow at least one year for an action to become effective. Other dates may apply. OPP FEAD 992
PRN 97-9: Electronic Submission Of Child-Resistant Packaging Test Data For All Pesticides 1997-01-01 2020-02-28 EPA 705-G-2020-0990 Pesticide Registration This pesticide registration notice addresses four issues related to child-resistant packaging. OPP FEAD 990
PRN 98-10: Notifications, Non-Notifications and Minor Formulation Amendments 1998-01-01 2020-02-28 EPA 705-G-2020-0658 Pesticide Registration This Pesticide Registration notice expands the changes to registration that may be made by notification and non-notification, maintains the expedited review of minor formulation changes, and modifies procedures for notifications of antimicrobial products. OPP FEAD 658
PRN 98-2: Liquid Chemical Sterilant Products 1998-01-01 2020-02-28 EPA 705-G-2020-0989 Pesticide Registration Liquid chemical sterilant products are no longer regulated as "pesticides" by the Environmental Protection Agency (EPA), but as "medical devices" under the regulatory authority of the Food and Drug Administration (FDA). OPP FEAD 989
PRN 98-3: Guidance on Final FIFRA 6(a)(2) Regulations for Pesticide Product Registrants 1998-01-01 2020-02-28 EPA 705-G-2020-0663 Pesticide Registration This notice provides registrants comprehensive guidance on implementing the adverse effects reporting regulations that were published in 1997. OPP FEAD 663
PRN 98-4: Additional Guidance on Final FIFRA Section 6(a)(2) Regulations for Pesticide Product Registrants w/Attachment 1998-01-01 2020-02-28 EPA 705-G-2020-0662 Pesticide Registration This Pesticide Registration Notice provides guidance on reporting information concerning unreasonable adverse effects of their products to EPA under the regulations promulgated in 1997. OPP FEAD 662
PRN 98-5: New Forms for the Certification with Respect to Citation of Data 1998-01-01 2020-02-28 EPA 705-G-2020-0661 Pesticide Registration In 1998, EPA established new forms for citation of data to support the registration or reregistration of pesticide products. These forms are EPA Form 8570-34 (“Certification with Respect to Citation of Data”) and 8570-35 (“Data Matrix”). OPP FEAD 661
PRN 98-6: Flammability Labeling Requirements for Total Release Fogger Pesticides 1998-01-01 2020-02-28 EPA 705-G-2020-0660 Pesticide Registration This notice describes new labeling requirements for total release foggers and provides the procedures and time frame for compliance. It ONLY affects total release foggers containing a propellant with a flash point at or below 20 degrees Fahrenheit. OPP FEAD 660
PRN 98-8: Waiver of Fees Associated with Tolerance Objections 1998-01-01 2020-02-28 EPA 705-G-2020-0988 Pesticide Registration EPA's regulations require that tolerance objections be accompanied by a filing fee of $3,275. This fee can be waived. This notice clarifies EPA's interpretation of the regulation. OPP FEAD 988
PRN 98-9: Modification of Respirator Statements for Pesticide Product Labels 1998-01-01 2020-02-28 EPA 705-G-2020-0659 Pesticide Registration This Pesticide Registration Notice informs registrants of technology improvements for respirators and designation changes for certain respirator filters required in pesticide labeling statements. OPP FEAD 659
PRN Notice 94-4: Interim Measures for the Registration of Antimicrobial Products/Liquid Chemical Germicides with Medical Device Use Claims Under the Memorandum of Understanding Between EPA and FDA 1994-01-01 2020-02-28 EPA 705-G-2020-1037 Pesticide Registration This Notice is intended to provide the regulated community with detailed guidance on the interim EPA registration procedures for antimicrobial products affected by the June 4, 1993, Memorandum of Understanding (MOU) between EPA and FDA. OPP FEAD 1037
PRN Notice 96-6: Pet Pesticide Product Label Statements 1996-01-01 2020-02-28 EPA 705-G-2020-1022 Pesticide Registration This notice specifies statements that should be added to the labels of pesticide products registered for use on dogs and/or cats. These label statements will help to ensure that products bear labeling to reduce the potential for misuse of pet products. OPP FEAD 1022
Qs and As from Federal Agencies on Federal Agency Certification Plans 2019-08-28 2020-02-28 EPA 705-G-2020-2527 Certification of Pesticide Applicators This document is intended to answer Federal agency questions on the 2017 Certification of Pesticide Applicators regulation. OPP FEAD 2527
Revising Certification Plans to Meet the Requirements of the 2017 Certification of Pesticide Applicators Final Rule Questions & Answers 2019-08-23 2020-02-28 EPA 705-G-2020-2525 Certification of Pesticide Applicators This document is intended for pesticide State Lead Agencies (SLAs), Tribes and Federal Agencies (“certifying authorities”) to answer their questions on the 2017 Certification of Pesticide Applicators regulation and the requirement to submit to EPA revised certification plans by March 4, 2020. OPP FEAD 2525
Rinsing Procedures for Dilutable Pesticide Products in Rigid Containers 2008-06-25 2020-02-28 EPA 705-G-2020-1277 Pesticide Worker Safety The pesticide container regulations establish standards for pesticide containers, repackaging, label instructions and to ensure safe use, reuse and disposal and adequate cleaning of the containers. OPP FEAD 1277
Scope of the Federal Pesticide Containment Regulations 2009-12-01 2020-02-28 EPA 705-G-2020-1283 Pesticide Worker Safety The purpose of this document is to help you determine whether the federal containment regulations require you to have a secondary containment unit and/or a containment pad. OPP FEAD 1283
Scope of the Non-refillable Container, Refillable Container, and Repackaging Regulations for Pesticide Containers 2016-08-24 2020-02-28 EPA 705-G-2020-1291 Pesticide Worker Safety Two flow charts: Scope of container and repackaging regulations and determining whether Antimicrobial products are exempt from or subject to regulations. OPP FEAD 1291
Secondary Containers and Service Containers for Pesticides 2015-10-26 2020-02-28 EPA 705-G-2020-2886 container; labels Explains what secondary containers and service containers are; EPA does not require labels on them; and, provides EPA recommendations for them. OPP FEAD 2886
Simple Comparison of the Major 2016 Revisions to the Existing Rule 2017-01-12 2020-02-28 EPA 705-G-2020-2912 Certification of Pesticide Applicators Comparison tables of the 2016 revisions to the Certification of Pesticide Applicator Rule to the existing rule. OPP FEAD 2912
State Certification Plan Outline 2019-04-29 2020-02-28 EPA 705-G-2020-2526 Certification of Pesticide Applicators This document serves as a model outline for the order and contents of state certification plans. OPP FEAD 2526
Table 4: Refillable container Requirements (40 CFR Part 165 Subpart C) 2008-10-01 2020-02-28 EPA 705-G-2020-2908 Refillable Container refillable container requirements OPP FEAD 2908
The Drift Reduction Technology Program 2014-01-01 2020-02-28 EPA 705-G-2020-0905 Reducing Pesticide Drift The new voluntary Drift Reduction Technology (DRT) Program will encourage the manufacture, marketing, and use of safer spray technology and equipment scientifically verified to reduce pesticide drift. OPP FEAD 905
Tribal Certification Plan Outline 2019-09-18 2020-02-28 EPA 705-G-2020-2529 Certification of Pesticide Applicators This document serves as a model outline for the order and contents of a tribal certification plan for those tribes that choose to develop their own certification plan under 40 CFR § 171.307(b). OPP FEAD 2529
Web-Distributed Labeling for Pesticide Products: Pesticide Registration Notice 2014-01-01 2020-02-28 EPA 705-G-2020-0614 Pesticide Registration This Notice presents the Agency's guidance on optional participation in web-distributed labeling for pesticide products. The Agency believes that voluntary adoption of these recommendations by pesticide registrants will help pesticide users to better understand and comply with pesticide labeling. In addition, the Agency believes that web-distributed labeling could allow addition of new uses, modification of existing labeling, and implementation of labeling-based risk mitigation measures more quickly.  OPP FEAD 614
Web-distributed Labeling for Pesticides 2014-01-01 2020-02-28 EPA 705-G-2020-2511 Pesticide Labeling Additional information on PR Notice 2014-1 including history of development, examples, and Q&As OPP FEAD 2511
Who Needs to Apply for Pesticide Applicator Certification in Indian Country under the EPA Plan 2018-09-11 2020-02-28 EPA 705-G-2020-0957 Pesticide Applicator Certification in Indian Country Any person who applies restricted use pesticides in an area of Indian country covered by the EPA plan will need a federal certificate from EPA. OPP FEAD 957
Worker Protection Standard (WPS) Comparison Chart: Comparison of the Revised Protections to the Previous Protections 2017-01-01 2020-02-28 EPA 705-G-2020-3594 Pesticide Worker Safety This table summarizes key provisions in the EPA’s previous WPS regulation and the 2015 revisions.  OPP FEAD 3594
Worker Protection Standard Application Exclusion Zone 2015-01-01 2020-02-28 EPA 705-G-2020-1521 Pesticide Worker Safety These documents provide general guidance to help you comply with the requirements of the Federal Worker Protection Standard (WPS) for agricultural pesticides, 40 CFR part 170, as amended in 2015. OPP FEAD 1521
Worker Protection Standard Application Exclusion Zone Requirements Updated Question and Answers 2018-02-15 2020-02-28 EPA 705-G-2020-2524 Pesticide Worker Safety This fact sheet contains further explanation of the Application Exclusion Zone (AEZ) requirement in the Agricultural Worker Protection Standard WPS. OPP FEAD 2524
Worker Protection Standard Frequently Asked Questions 40 CFR Part 170 2016-04-14 2020-02-28 EPA 705-G-2020-2523 Pesticide Worker Safety Frequently asked questions and answers related to the WPS rule change in 2015 - published in April 2016. OPP FEAD 2523
Worker Protection Standard Relabeling Process for Retailers and Wholesalers 1995-10-23 2020-02-28 EPA 705-G-2020-0667 Pesticide Registration This is Attachment 1 for Pesticide Registration Notice 95-5, Labeling Revisions Required By The Worker Protection Standard (WPS) for Sale or Distribution of Certain Agricultural Pesticides after October 23, 1995. OPP FEAD 667
Worker Protection Standard Train-the-Trainer Programs, Approval Process and Criteria 2017-08-01 2020-02-28 EPA 705-G-2020-1573 Pesticide Worker Safety EPA has prepared guidance material to facilitate the development of Train-the-Trainer programs that meet EPA requirements. OPP FEAD 1573
(Quantitative) Structure Activity Relationship [(Q)SAR] Guidance Document (NAFTA) 2012-11-01 2020-02-28 EPA 705-G-2020-1496 Pesticide Registration Guidance Document developed by the NAFTA Technical Working Group on the Quantitative Structure Activity Relationship. (Q)SAR represents a variety of techniques for predicting activities and properties of untested chemicals based on their structural similarity to chemicals with known activities and properties. OPP HED 1496
28-Day Dermal Toxicity - [species] 2010-07-01 2020-02-28 EPA 705-G-2020-3337 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3337
90-Day Dermal Toxicity - [species] 2010-07-01 2020-02-28 EPA 705-G-2020-3338 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3338
90-Day Oral Toxicity [dietary, gavage or drinking water] - [non-rodent species] 2010-07-01 2020-02-28 EPA 705-G-2020-3336 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3336
90-Day Oral Toxicity [dietary, gavage or drinking water] - [rodent species] 2010-07-01 2020-02-28 EPA 705-G-2020-3335 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3335
Agricultural Post Application Passive Dosimetry 2010-07-01 2020-02-28 EPA 705-G-2020-3364 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3364
Assigning Values to Nondetected/ Nonquantified Pesticide Residues in Human Health Dietary Exposure Assessments  2000-03-23 2020-02-28 EPA 705-G-2020-0007 Dietary Exposure; Human Health Risk Assessment; Pesticide Residues; Non-Detected Residues; Limit of Quantification OPP’s policy for assigning values for use in human health exposure and risk assessment to non-detected/non-quantified pesticide residues in food. In general, EPA recommends use of a value of ½ the analytical Limit of Detection (LOD), ½ the Limit of Quantitation (LOQ), the (full) Lower Limit of Method Validation (LLMV), or true zero for these non-detected residues. OPP HED 7
Available EPA Information on Assessing Exposure to Pesticides in Food- A User's Guide 2000-06-21 2020-02-28 EPA 705-G-2020-0008 Dietary Exposure; Pesticide Residues in Food; Human Health Risk Assessment Provides a simple overview of EPA's approach to estimating risk and exposure from pesticide residues in food, provides specifics on how to obtain or generate the data and/or information EPA uses in its assessments of exposure and risk from pesticides in food; and provides a list of helpful resources by topic area. OPP HED 8
B.5.2 Residue Analytical Methods 2016-02-01 2020-02-28 EPA 705-G-2020-3321 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3321
B.7 Residue Data 2016-02-01 2020-02-28 EPA 705-G-2020-3318 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3318
B.7.1 Plant Metabolism 2016-02-01 2020-02-28 EPA 705-G-2020-3319 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3319
B.7.2 Livestock Metabolism 2016-02-01 2020-02-28 EPA 705-G-2020-3320 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3320
B.7.6 Crop Residue Trials 2016-02-01 2020-02-28 EPA 705-G-2020-3325 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3325
B.7.6.2 Freezer Storage Stability in Plants 2016-02-01 2020-02-28 EPA 705-G-2020-3322 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3322
B.7.7 Processing 2016-02-01 2020-02-28 EPA 705-G-2020-3326 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3326
B.7.8 Livestock Feeding 2016-02-01 2020-02-28 EPA 705-G-2020-3324 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3324
B.7.8.3 Freezer Storage Stability in Livestock 2016-02-01 2020-02-28 EPA 705-G-2020-3323 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3323
B.7.9 Confined Crop Rotation 2016-02-01 2020-02-28 EPA 705-G-2020-3327 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3327
B.7.9.2 Field Accumulation 2016-02-01 2020-02-28 EPA 705-G-2020-3328 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3328
Carcinogenicity [dietary, gavage, drinking water, dermal or inhalation] - Mouse 2010-07-01 2020-02-28 EPA 705-G-2020-3347 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3347
Carcinogenicity [dietary, gavage, drinking water, dermal or inhalation] - Rat 2010-07-01 2020-02-28 EPA 705-G-2020-3348 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3348
Choosing a Percentile of Acute Dietary Exposure as a Threshold of Regulatory Concern 2000-03-16 2020-02-28 EPA 705-G-2020-0009 Acute Dietary Exposure; Pesticide Residues in Food; Human Health Risk Assessment EPA is responsible for regulating the nature and amount of pesticide residues in food under the Federal Food, Drug and Cosmetic Act (FFDCA). The Agency performs various types of risk assessments to evaluate the safety of pesticides in food, including analyses to determine the nature and the amounts of pesticides that people might be exposed to over a single day. This paper discusses how EPA generally applies the statutory safety standard to acute dietary risk assessments as to pesticide residues in foods. OPP HED 9
Chronic Toxicity [dietary, gavage, drinking water, dermal or inhalation] - [rodent species] 2010-07-01 2020-02-28 EPA 705-G-2020-3343 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3343
Chronic Toxicity [feeding, water, dermal or inhalation] - [non-rodent species] 2010-07-01 2020-02-28 EPA 705-G-2020-3344 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3344
Classification of Seed Treatments as Food or Nonfood Uses 1999-10-28 2020-02-28 EPA 705-G-2020-2429 seed treatment; food; nonfood Chem SAC determination of seed treatment uses as food versus nonfood based on the results of radiolabeled studies OPP HED 2429
Combined Chronic Toxicity/Carcinogenicity [dietary, gavage, drinking water, dermal or inhalation] - [species] 2010-07-01 2020-02-28 EPA 705-G-2020-3349 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3349
Conclusions and Recommendations Regarding the Requirement for Inclusion of Adjuvants in Crop Field Trials 2012-08-13 2020-02-28 EPA 705-G-2020-2643 Pesticide Crop Field Trials Conclusions and Recommendations Regarding the Requirement for Inclusion of Adjuvants in Crop Field Trials. OPP HED 2643
Data for Refining Anticipated Residue Estimates Used in Acute Dietary Probabilistic Risk Assessments  2000-06-15 2020-02-28 EPA 705-G-2020-0011 Pesticide Data; Anticipated Residues; Dietary Exposure; Human Health Risk Assessment The purpose of this document is to outline the types of data EPA's Office of Pesticide Programs can use to refine residue estimates for pesticides and explain when and how these data may be used. Specifically, this document is intended to provide additional guidance to registrants, other test sponsors, interested parties, and data reviewers on the extent and quality of pesticide residue and ancillary data needed to support the use of more refined “anticipated residues” in dietary exposure assessments. OPP HED 11
Decision Tree for Seed Treatment (Excluding Potato Seed-Piece Treatment) 2018-01-26 2020-02-28 EPA 705-G-2020-2428 seed treatment; decision tree Diagrammatic representation of a decision Tree for the Residue Data Requirements excluding Potato Seed-Piece (PSP) Treatments. OPP HED 2428
Decision Tree for the Residue Data Requirements of Potato Seed-Piece (PSP) Treatments 2018-01-26 2020-02-28 EPA 705-G-2020-2427 seed treatment; PSP; decision tree Diagrammatic representation of a decision Tree for the Residue Data Requirements of Potato Seed-Piece (PSP) Treatments. OPP HED 2427
Dermal Penetration 2010-07-01 2020-02-28 EPA 705-G-2020-3359 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3359
Determination of the Appropriate FQPA Safety Factor(s) in Tolerance Assessment 2002-02-28 2020-02-28 EPA 705-G-2020-0012 Food Quality Protection Act; FQPA Safety Factor; Pesticide Exposure; Human Health Risk Assessment This document describes how the Office of Pesticide Programs (OPP) determines the appropriate FQPA safety factor(s) when developing aggregate risk assessments and regulatory decisions for single active and "other" (i.e., inert) ingredients of pesticide products. The guidance is specifically addressed to OPP risk assessors but also serves as an important source of information for the public and the regulated community. OPP HED 12
Determination of Transferable Residue on Indoor Treated Surfaces 2010-07-01 2020-02-28 EPA 705-G-2020-3367 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3367
Determining the Number of Field Trials Required to Register Seed-Treatment Uses 2018-02-01 2020-02-28 EPA 705-G-2020-2425 seed treatment This page includes the guidance memo, decision trees and additional reference documents to help a manufacturer determine how many field trials are necessary to register seed-treatment uses. OPP HED 2425
Determining Toxicology Data Requirements 2013-05-01 2020-02-28 EPA 705-G-2020-0594 Pesticide Registration Provide guidance on the weight of the evidence-based (WOE) determination of data needs for neurotoxicity, subchronic inhalation, subchronic, dermal and immunotoxicity studies and provide guidance on how to consider the data needs determination in risk assessment. Evaluation of waiver requests and development of registration review cases are typical situations in which OPP reviewers will make data need determinations. OPP HED 594
Developing a Tiered Framework for Extrapolation Modeling 2017-03-14 2020-02-28 EPA 705-G-2020-2808 Pesticide Registration This is a web page describing how EPA extrapolates from animals to humans in its risk assessments OPP HED 2808
Developmental Neurotoxicity Study - Rat 2010-07-01 2020-02-28 EPA 705-G-2020-3357 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3357
Developmental Neurotoxicity Study Guidance (NAFTA) 2016-12-01 2020-02-28 EPA 705-G-2020-1655 Pesticide Science and Assessing Pesticide Risks This guidance covers review and interpretation of DNT data and was developed collaboratively by EPA and Health Canada, with the goal of more consistent reviews of DNT data. OPP HED 1655
Dislodgeable Foliar Residue 2010-07-01 2020-02-28 EPA 705-G-2020-3366 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3366
Dislodgeable Turf Residues 2010-07-01 2020-02-28 EPA 705-G-2020-3365 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3365
E-Submission Chronic Toxicology Study Supplemental Files 2002-07-01 2020-02-28 EPA 705-G-2020-3131 Electronic Submission; Toxicology Data; Pesticide Registration The formats and instructions in these documents are designed to be used as an example or guide for registrants to format electronic files for submission of animal toxicology data to the EPA's Office of Pesticide Programs for review in support of registration and reevaluation of pesticides. OPP HED 3131
General Principles for Performing Aggregate Exposure and Risk Assessments  2001-11-28 2020-02-28 EPA 705-G-2020-0014 Human Health Risk Assessment; Aggregate exposure; Pesticides; Exposure Pathways This document describes OPP's overall framework and the general principles for performing an aggregate exposure and risk assessment. Aggregate exposure and risk assessment involve the analysis of exposure to a single chemical by multiple pathways (e.g., food, drinking water, and residential uses) and routes (ingestion, dermal, and inhalation). OPP HED 14
Guidance and Examples for Supplementary Tumor Data Spreadsheet for Toxicology 870.4200 and 870.4300 2012-02-01 2020-02-28 EPA 705-G-2020-3346 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3346
Guidance for Identifying Pesticide Chemicals and Other Substances That Have a Common Mechanism of Toxicity  1999-01-29 2020-02-28 EPA 705-G-2020-0015 Pesticide Chemicals; Common Mechanism of Toxicity; Cumulative Risk Assessment The purpose of this document is to describe the approach that EPA will use for identifying and categorizing pesticides and other substances that cause common toxic effects from common mechanisms of toxicity. OPP HED 15
Guidance for Reduced Residue Field Trial Requirements to Support Joint Projects Between Canada and the United States 2018-08-23 2020-02-28 EPA 705-G-2020-2539 Crop Field Trials The purpose of this document is to communicate to industry and other interested parties, the revised crop trial requirements for trials that are conducted to support simultaneous domestic registration applications in both Canada and the United States. OPP HED 2539
Guidance for Thyroid Assays in Pregnant Animals, Fetuses and Postnatal Animals, and Adult Animals 2005-10-24 2020-02-28 EPA 705-G-2020-1286 Pesticide Registration This study may be done in place of a rat DNT study for thyroid disrupting chemicals. This special study is intended to provide LOAEL or NOAEL to derive RfDs to be protective of thyroid development in pregnant women, fetuses or newborns. OPP HED 1286
Guidance on Cumulative Risk Assessment of Pesticide Chemicals That Have a Common Mechanism of Toxicity  2002-01-14 2020-02-28 EPA 705-G-2020-0016 Cumulative Risk Assessment; Pesticide Exposure; Common Mechanism of Toxicity This document describes OPP's process for assembling and evaluating information that will constitute a cumulative risk assessment involving food, water, residential, and other nonoccupational exposures to multiple pesticides that share a common mechanism of toxicity. OPP HED 16
Hand Press Residues 2010-07-01 2020-02-28 EPA 705-G-2020-3368 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3368
Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.1000, Acute Toxicity Testing-Background 2002-12-01 2020-02-28 EPA 712-C-02-189 Test Guideline; Health Effects  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 274
Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.1100, Acute Oral Toxicity (AOT) 2002-12-01 2020-02-28 EPA 712-C-02-190 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review OPP HED 275
Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.1200, Acute Dermal Toxicity 1998-08-01 2020-02-28 EPA 712-C-98-192 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 276
Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.1300, Acute Inhalation Toxicity 1998-08-01 2020-02-28 EPA 712-C-98-193 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 277
Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.2400, Acute Eye Irritation 1998-08-01 2020-02-28 EPA 712-C-98-195 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 279
Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.2500, Acute Dermal Irritation 1998-08-01 2020-02-28 EPA 712-C-98-196 Test Guideline; Health Effects  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 280
Health Effects Test Guidelines: Acute Toxicity Test Guidelines, 870.2600, Skin Sensitization 2003-03-01 2020-02-28 EPA 712-C-03-197 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 281
Health Effects Test Guidelines: Chronic Toxicity Test Guidelines, 870.4100, Chronic Toxicity 1998-08-01 2020-02-28 EPA 712-C-98-210 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 294
Health Effects Test Guidelines: Chronic Toxicity Test Guidelines, 870.4200, Carcinogenicity 1998-08-01 2020-02-28 EPA 712-C-98-211 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 295
Health Effects Test Guidelines: Chronic Toxicity Test Guidelines, 870.4300, Combined Chronic Toxicity/Carcinogenicity 1998-08-01 2020-02-28 EPA 712-C-98-212 Test Guideline; Health Effects  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 296
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5100, Bacterial Reverse Mutation Test 1998-08-01 2020-02-28 EPA 712-C-98-247 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 297
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5140, Gene Mutation in Aspergillus nidulans 1998-08-01 2020-02-28 EPA 712-C-98-215 Test Guideline; Health Effects  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 298
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5195, Mouse Biochemical Specific Locus Test 1998-08-01 2020-02-28 EPA 712-C-98-216 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 299
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5200, Mouse Visible Specific Locus Test 1998-08-01 2020-02-28 EPA 712-C-98-217 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 300
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5250, Gene Mutation in Neurospora crassa 1998-08-01 2020-02-28 EPA 712-C-98-218 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 301
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5275, Sex-linked Recessive Lethal Test in Drosophila melanogaster 1998-08-01 2020-02-28 EPA 712-C-98-220 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 303
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5300, In vitro Mammalian Cell Gene Mutation Test 1998-08-01 2020-02-28 EPA 712-C-98-221 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 304
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5375, In Vitro Mammalian Chromosome Aberration Test 1998-08-01 2020-02-28 EPA 712-C-98-223 Test Guidelines; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 305
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5380, Mammalian Spermatogonial Chromosomal Aberration Test 1998-08-01 2020-02-28 EPA 712-C-98-224 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 306
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5385, Mammalian Bone Marrow Chromosomal Aberration Test 1998-08-01 2020-02-28 EPA 712-C-98-225 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 307
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5395, Mammalian Erythrocyte Micronucleus Test 1998-08-01 2020-02-28 EPA 712-C-98-226 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 308
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5450, Rodent Dominant Lethal Assay 1998-08-01 2020-02-28 EPA 712-C-98-227 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 309
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5460, Rodent Heritable Translocation Assays 1998-08-01 2020-02-28 EPA 712-C-98-228 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 310
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5500, Bacterial DNA Damage or Repair Tests 1998-08-01 2020-02-28 EPA 712-C-98-229 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 311
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5550, Unscheduled DNA Synthesis in Mammalian Cells in Culture 1998-08-01 2020-02-28 EPA 712-C-98-230 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 312
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5575, Mitotic Gene Conversion in Saccharomyces cerevisiae 1998-08-01 2020-02-28 EPA 712-C-98-232 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 313
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5900, In Vitro Sister Chromatid Exchange Assay 1998-08-01 2020-02-28 EPA 712-C-98-234 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 314
Health Effects Test Guidelines: Genetic Toxicity Test Guidelines, 870.5915, In Vitro Sister Chromatid Exchange Assay 1998-08-01 2020-02-28 EPA 712-C-98-235 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 315
Health Effects Test Guidelines: Health Effects Chemical-Specific Test Guidelines, 870.8355, Combined Chronic Toxicity/Carcinogenicity Testing of Respirable Fibrous Particles 2001-07-01 2020-02-28 EPA 712-C-01-352 Test Guidelines; Health Effects  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 326
Health Effects Test Guidelines: Neurotoxicity Test Guidelines, 870.6100, Acute and 28-day Delayed Neurotoxicity of Organophosphorus Substances 1998-08-01 2020-02-28 EPA 712-C-98-237 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 316
Health Effects Test Guidelines: Neurotoxicity Test Guidelines, 870.6200, Neurotoxicity Screening Battery 1998-08-01 2020-02-28 EPA 712-C-98-238 Test Guideline; Health Effects  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 317
Health Effects Test Guidelines: Neurotoxicity Test Guidelines, 870.6300, Developmental Neurotoxicity Study 1998-08-01 2020-02-28 EPA 712-C-98-239 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 318
Health Effects Test Guidelines: Neurotoxicity Test Guidelines, 870.6500, Schedule-Controlled Operant Behavior 1998-08-01 2020-02-28 EPA 712-C-98-240 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 319
Health Effects Test Guidelines: Neurotoxicity Test Guidelines, 870.6850, Peripheral Nerve Function 1998-08-01 2020-02-28 EPA 712-C-98-241 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 320
Health Effects Test Guidelines: Neurotoxicity Test Guidelines, 870.6855, Neurophysiology: Sensory Evoked Potentials 1998-08-01 2020-02-28 EPA 712-C-98-242 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 321
Health Effects Test Guidelines: Special Studies Test Guidelines, 870.7200, Companion Animal Safety 1998-08-01 2020-02-28 EPA 712-C-98-349 Test Guideline; Health Effects  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 322
Health Effects Test Guidelines: Special Studies Test Guidelines, 870.7485, Metabolism and Pharmacokinetics 1998-08-01 2020-02-28 EPA 712-C-95-244 Test Guideline; Health Effects  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 323
Health Effects Test Guidelines: Special Studies Test Guidelines, 870.7600, Dermal Penetration 1998-08-01 2020-02-28 EPA 712-C-98-350 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 324
Health Effects Test Guidelines: Special Studies Test Guidelines, 870.7800, Immunotoxicity 1998-08-01 2020-02-28 EPA 712-C-98-351 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 325
Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3050, Repeated Dose 28-day Oral Toxicity Study in Rodents 2000-07-01 2020-02-28 EPA 712-C-00-366 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 282
Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3100, 90-Day Oral Toxicity in Rodents 1998-08-01 2020-02-28 EPA 712-C-98-199 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 283
Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3150, 90-Day Oral Toxicity in Nonrodents 1998-08-01 2020-02-28 EPA 712-C-98-200 Test Guideline; Health Effects  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 284
Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3200, 21/28-Day Dermal Toxicity 1998-08-01 2020-02-28 EPA 712-C-98-201 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 285
Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3250, 90-Day Dermal Toxicity 1998-08-01 2020-02-28 EPA 712-C-98-202 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 286
Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3465, 90-Day Inhalation Toxicity 1998-08-01 2020-02-28 EPA 712-C-98-204 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 287
Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3550, Reproduction/Development Toxicity Screening Test 2000-07-01 2020-02-28 EPA 712-C-00-367 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 289
Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3650, Combined Repeated Dose Toxicity with the Reproduction/Development Toxicity Screening Test 2000-07-01 2020-02-28 EPA 712-C-00-368 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 291
Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3700, Prenatal Developmental Toxicity Study 1998-08-01 2020-02-28 EPA 712-C-98-207 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 292
Health Effects Test Guidelines: Subchronic Toxicity Test Guidelines, 870.3800, Reproduction and Fertility Effects 1998-08-01 2020-02-28 EPA 712-C-98-208 Test Guideline; Health Effects The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 293
Immunotoxicity 2010-07-01 2020-02-28 EPA 705-G-2020-3360 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3360
In Vitro Mammalian Cells in Culture Gene Mutation Assay in [name cell type used] cells 2010-07-01 2020-02-28 EPA 705-G-2020-3351 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3351
In Vitro Mammalian Cytogenetics (specify assay) or In Vitro Sister Chromatid Exchange Assay in (name species/cell type) 2010-07-01 2020-02-28 EPA 705-G-2020-3352 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3352
In Vitro Microbial Gene Mutation 2010-07-01 2020-02-28 EPA 705-G-2020-3350 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3350
In Vivo Mammalian Cytogenetics - Erythrocyte Micronucleus Assay in [name species] 2010-07-01 2020-02-28 EPA 705-G-2020-3353 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3353
Interim Science Policy: Use of Alternative Approaches for Skin Sensitization as a Replacement for Laboratory Animal Testing Draft for Public Comment 2018-04-04 2020-02-28 EPA 705-G-2020-3111 Alternative Approaches; Testing Methods; Skin Sensitization This document describes the science supporting an interim science policy on the acceptance of alternative (in vitro, in silico, in chemico) approaches for identifying skin sensitization hazard. These approaches will be accepted in lieu of laboratory animal studies, most often the local lymph node assay (LLNA) in the mouse (OECD TG 429; OECD 2010a), and Buehler or maximization tests in the guinea pig (OECD TG 406, OECD 2010a). Although this document is a draft for public comment, given the substantial scientific evidence and international activities supporting NAMs for skin sensitization, OPP and OPPT will begin accepting these approaches immediately under the conditions described within. OPP HED 3111
Metabolism Study - Rat 2010-07-01 2020-02-28 EPA 705-G-2020-3358 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3358
Mixer/Loader/Applicator Passive Dosimetry 2010-07-01 2020-02-28 EPA 705-G-2020-3363 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3363
NAFTA Guidance Document on Data Requirements for Tolerances on Imported Commodities in the United States and Canada 2005-12-01 2020-02-28 EPA 705-G-2020-2422 data requirement; tolerance; MRL; NAFTA Provides detailed guidance on data requirements that meet the North American Free Trade Agreement (NAFTA) standards for the establishment of pesticide import tolerances or maximum residue levels (MRL) in Canada and the United States.  OPP HED 2422
Neurotoxicity Screening Battery - Rat (Acute) 2010-07-01 2020-02-28 EPA 705-G-2020-3355 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3355
Neurotoxicity Screening Battery - Rat (Subchronic) 2010-07-01 2020-02-28 EPA 705-G-2020-3356 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3356
Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1000, Background for Application Exposure Monitoring Test Guidelines 1996-02-01 2020-02-28 EPA 712-C-96-261 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 353
Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1100, Dermal Exposure—Outdoor 1996-02-01 2020-02-28 EPA 712-C-96-262 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 354
Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1200, Dermal Exposure—Indoor 1996-02-01 2020-02-28 EPA 712-C-96-209 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 355
Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1300, Inhalation Exposure—Outdoor 1996-02-01 2020-02-28 EPA 712-C-96-263 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 356
Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1400, Inhalation Exposure—Indoor 1996-02-01 2020-02-28 EPA 712-C-96-213 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 357
Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1500, Biological Monitoring 1996-02-01 2020-02-28 EPA 712-C-96-264 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 358
Occupational and Residential Exposure Test Guidelines: Applicator Exposure Monitoring Test Guidelines, 875.1600, Application Exposure Monitoring Data Reporting 1996-02-01 2020-02-28 EPA 712-C-96-265 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 359
Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2000, Background for Postapplication Exposure Monitoring Test Guidelines 1996-02-01 2020-02-28 EPA 712-C-96-266 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 360
Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2100, Foliar Dislodgeable Residue Dissipation 1996-02-01 2020-02-28 EPA 712-C-96-267 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 361
Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2200, Soil Residue Dissipation 1996-02-01 2020-02-28 EPA 712-C-96-243 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 362
Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2400, Dermal Exposure 1996-02-01 2020-02-28 EPA 712-C-96-269 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 363
Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2500, Inhalation Exposure 1996-02-01 2020-02-28 EPA 712-C-96-270 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 364
Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2600, Biological Monitoring 1996-02-01 2020-02-28 EPA 712-C-96-271 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 365
Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2800, Descriptions of Human Activity 1996-02-01 2020-02-28 EPA 712-C-96-283 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 366
Occupational and Residential Exposure Test Guidelines: Postapplication Exposure Monitoring Test Guidelines, 875.2900, Data Reporting and Calculations 1996-02-01 2020-02-28 EPA 712-C-96-272 Test Guideline; Occupational and Residential Exposure The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 367
Other Genotoxicity: Unscheduled DNA Synthesis in Primary Rat Hepatocytes / Mammalian Cell Culture 2010-07-01 2020-02-28 EPA 705-G-2020-3354 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3354
Pesticide Cumulative Risk Assessment: Framework for Screening Analysis 2015-06-23 2020-02-28 EPA 705-G-2020-1561 Pesticide Science; Assessing Pesticide Risks; Cumulative Risk Assessment; Screening Approach This document provides guidance on how to screen groups of pesticides for cumulative evaluation using a two-step approach: beginning with the evaluation of available toxicological information and, if necessary, followed by a risk-based screening approach. This framework supplements the existing guidance documents for establishing common mechanism groups (CMGs) and conducting cumulative risk assessments (CRA). OPP HED 1561
Preferred Vocabulary for Establishing Pesticide Tolerances 2017-09-27 2020-02-28 EPA 705-G-2020-2344 Pesticide Tolerances; Vocabulary This document presents stakeholders who propose pesticide tolerances and regulatory staff charged with reviewing those proposals with the preferred vocabulary terms both for individual commodities and crop groups and subgroups OPP HED 2344
Prenatal Developmental Toxicity Study - [non-rodent species] 2010-07-01 2020-02-28 EPA 705-G-2020-3341 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3341
Prenatal Developmental Toxicity Study - [rodent species] 2010-07-01 2020-02-28 EPA 705-G-2020-3340 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3340
Proposed Approach to Efficiently Develop Physiologically Based Pharmacokinetic (PBPK) & Physiologically Based Pharmacokinetic-Pharmacodynamic (PBPK-PD) Models for Pesticides 2017-03-14 2020-02-28 EPA 705-G-2020-2813 Computational Modelling; PBPK; PBPK-PD Models This document describes OPP's tiered framework for extrapolation modeling for animal >> human testing data. OPP HED 2813
Reduced Residue Chemistry Data Requirements for Seed-Treatment Uses 2018-01-26 2020-02-28 EPA 705-G-2020-2426 seed treatment This document provides a tiered approach for determining if current crop-specific field trial data are required to support new seed treatment uses or if a reduction in number of field trials is appropriate. OPP HED 2426
Reproduction and Fertility Effects Study - [species] 2010-07-01 2020-02-28 EPA 705-G-2020-3342 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3342
Residential Post Application Passive Dosimetry 2010-07-01 2020-02-28 EPA 705-G-2020-3362 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3362
Residue Chemistry Test Guidelines: 860.1000 Supplement, Guidance on Constructing Maximum Reasonably Balanced Diets (MRBD) 2008-06-30 2020-02-28 EPA 705-G-2020-0273 Test Guideline; Residue Chemistry; Feedstuffs Revision The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 273
Residue Chemistry Test Guidelines: 860.1000, Background 1996-08-01 2020-02-28 EPA 712-C-96-169 Test Guideline; Residue Chemistry  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 256
Residue Chemistry Test Guidelines: 860.1100, Chemical Identity 1996-08-01 2020-02-28 EPA 712-C-96-170 Test Guideline; Residue Chemistry  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 257
Residue Chemistry Test Guidelines: 860.1200, Directions for Use 1996-08-01 2020-02-28 EPA 712-C-96-171 Test Guideline; Residue Chemistry The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 258
Residue Chemistry Test Guidelines: 860.1300, Nature of the Residue—Plants, Livestock 1996-08-01 2020-02-28 EPA 712-C-96-172 Test Guideline; Residue Chemistry The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 259
Residue Chemistry Test Guidelines: 860.1340, Residue Analytical Method 1996-08-01 2020-02-28 EPA 712-C-96-174 Test Guideline; Residue Chemistry The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 260
Residue Chemistry Test Guidelines: 860.1360, Multiresidue method 1996-08-01 2020-02-28 EPA 712-C-96-176 Test Guideline; Residue Chemistry  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 261
Residue Chemistry Test Guidelines: 860.1380, Storage Stability Data 1996-08-01 2020-02-28 EPA 712-C-96-177 Test Guideline; Residue Chemistry The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 262
Residue Chemistry Test Guidelines: 860.1400, Water, Fish, and Irrigated Crops 1996-08-01 2020-02-28 EPA 712-C-96-178 Test Guideline; Residue Chemistry The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 263
Residue Chemistry Test Guidelines: 860.1460, Food Handling 1996-08-01 2020-02-28 EPA 712-C-96-181 Test Guideline; Residue Chemistry  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 264
Residue Chemistry Test Guidelines: 860.1480, Meat/Milk/Poultry/Eggs 1996-08-01 2020-02-28 EPA 712-C-96-182  Test Guideline; Residue Chemistry The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 265
Residue Chemistry Test Guidelines: 860.1500, Crop Field Trials 1996-08-01 2020-02-28 EPA 712-C-96-183 Test Guideline; Residue Chemistry  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 266
Residue Chemistry Test Guidelines: 860.1520, Processed Food/Feed 1996-08-01 2020-02-28 EPA 712-C-96-184 Test Guideline; Residue Chemistry The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 267
Residue Chemistry Test Guidelines: 860.1550, Proposed Tolerances 1996-08-01 2020-02-28 EPA 712-C-96-186 Test Guideline; Residue Chemistry The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 268
Residue Chemistry Test Guidelines: 860.1560, Reasonable Grounds in Support of the Petition 1996-08-01 2020-02-28 EPA 712-C-96-187 Test Guideline; Residue Chemistry The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 269
Residue Chemistry Test Guidelines: 860.1650, Submittal of Analytical Reference Standards 2008-11-01 2020-02-28 EPA 712-F-08-001 Test Guideline; Residue Chemistry  The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 270
Residue Chemistry Test Guidelines: 860.1850, Confined Accumulation in Rotational Crops 1996-08-01 2020-02-28 EPA 712-C-96-188 Test Guideline; Residue Chemistry The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 271
Residue Chemistry Test Guidelines: 860.1900, Field Accumulation in Rotational Crops 1996-08-01 2020-02-28 EPA 712-C-96-189 Test Guideline; Residue Chemistry The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 272
Spray Drift Test Guidelines: , 840.1000, Background for Pesticide Aerial Drift Evaluation 1998-03-01 2020-02-28 EPA 712-C-98-319 Test Guideline; Spray Drift The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 149
Spray Drift Test Guidelines: , 840.1100, Spray Droplet Size Spectrum 1998-03-01 2020-02-28 EPA 712-C-98-055 Test Guidelines; Spray Drift The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 150
Spray Drift Test Guidelines: , 840.1200, Spray Drift Field Deposition 1998-03-01 2020-02-28 EPA 712-C-98-112 Test Guideline; Spray Drift The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP HED 151
Standard Format for Electronic Submission of Supplemental Data Files in Support of Chronic/Sub-Chronic Studies. 2002-07-31 2020-02-28 EPA 705-G-2020-3132 Electronic Submission; Toxicology Data; Pesticide Registration The following formats and instructions are designed to be used as an example or guide for registrants to format electronic files for submission of animal toxicology data to the USEPA Office of Pesticide Programs for review in support of registration and re-registration of pesticides. OPP HED 3132
Standard Format for Electronic Submission of Supplemental Data Files in Support of Developmental Neurotoxicity (DNT) Studies. 2002-07-31 2020-02-28 EPA 705-G-2020-3133 Electronic Submission; Toxicology Data; Pesticide Registration The following formats and instructions are designed to be used as an example or guide for registrants to format electronic files for submission of animal toxicology data to the USEPA Office of Pesticide Programs for review in support of registration and re-registration of pesticides. OPP HED 3133
Standard Format for Electronic Submission of Supplemental Data Files in Support of Multi-Generation Reproduction Studies. 2002-07-31 2020-02-28 EPA 705-G-2020-3135 Electronic Submission; Toxicology Data; Pesticide Registration The following formats and instructions are designed to be used as an example or guide for registrants to format electronic files for submission of animal toxicology data to the USEPA Office of Pesticide Programs for review in support of registration and re-registration of pesticides. OPP HED 3135
Standard Format for Electronic Submission of Supplemental Data Files in Support of Prenatal Developmental Toxicity Data. 2002-07-31 2020-02-28 EPA 705-G-2020-3134 Electronic Submission; Toxicology Data; Pesticide Registration registrants to format electronic files for submission of animal toxicology data to the USEPA Office of Pesticide Programs for review in support of registration and re-registration of pesticides. OPP HED 3134
Subchronic Inhalation Toxicity - [species] 2010-07-01 2020-02-28 EPA 705-G-2020-3339 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3339
Supplementary Tumor Data Spreadsheet for Toxicology 870.4200 and 870.4300 2012-02-01 2020-02-28 EPA 705-G-2020-3345 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3345
The Use of Data on Cholinesterase Inhibition for Risk Assessments of Organophosphorous and Carbamate Pesticides 2000-08-18 2020-02-28 EPA 705-G-2020-0045 Human Health Risk Assessment; Cholinesterase inhibition; Organophosphate; Carbamate; Pesticides This science policy document describes the approaches that the Office of Pesticide Programs (OPP) employs when evaluating data on cholinesterase inhibition and other cholinergic effects related to nervous system function that are the consequences of acetycholinesterase inhibition (i.e., physiological or behavioral 2007changes) in assessing the potential hazard following exposure to organophosphorous or carbamate pesticides that inhibit cholinesterase. OPP HED 45
Thyroid Disrupting Pesticides:  Use of Rat Thyroid Data and Application of Uncertainty Factors for RfD Derivation 2005-11-01 2020-02-28 EPA 705-G-2020-2341 Uncertainty Factors The objective of this paper is to provide guidance on the use of toxicokinetic or dynamic information to replace the current standard default 10X uncertainty factors which are applied to address interspecies and interindividual (human) differences in the dose–response assessment for pesticides that have been shown to disrupt thyroid function in rats.  OPP HED 2341
Use Pattern/Exposure Scenarios 2010-07-01 2020-02-28 EPA 705-G-2020-3361 Study Profile Template Study profile templates serve as a guide for the preparation of study documents. Applicants may include additional information beyond that prescribed in a particular study profile; however, it should be done without affecting or changing the format and content of the template. OPP HED 3361
Appeals of Fee and Waiver Decisions 2019-01-01 2020-02-28 EPA 705-G-2020-0603 PRIA Fees Describes how an applicant can appeal a fee or waiver determination by the EPA. OPP IO 603
Checklists for 45/90 Preliminary Technical Screen 2018-01-01 2020-02-28 EPA 705-G-2020-0605 PRIA Fees Applicant may use checklists to ensure that their application is complete and ready for in-depth review, as required by FIFRA. Applicants may submit the checklists with their application. OPP IO 605
Data Requirements Checklists for PRIA Fee Categories 2014-03-10 2020-02-28 EPA 705-G-2020-0601 PRIA Fees Data requirements checklists for PRIA fee categories OPP IO 601
EPA CDX SmartLabel Builder User Guide Version 2  2018-04-18 2020-02-28 EPA 705-G-2020-3598 OPPEL This document provides information on EPA's OPPEL Builder is a Structured Product Label (SPL) document builder, located within the EPA’s Central Data Exchange (CDX). The  SPL Builder is the Agency’s publicly offered tool to build, validate, and submit structured xml files to the EPA for review and registration. OPP IO 3598
Exemptions for Federal and State Governments under PRIA 2016-01-01 2020-02-28 EPA 705-G-2020-2512 PRIA Information on how an agency of the federal government or a state government shall be exempt from covered registration service fees. OPP IO 2512
Factors for IR-4 Public Interest Finding 2019-01-01 2020-02-28 EPA 705-G-2020-2516 PRIA Information on the factors the Agency considers to make an IR-4 public interest finding for a PRIA registration service fee exemption OPP IO 2516
Fee Reduction Tables 2019-09-26 2020-02-28 EPA 705-G-2020-0607 PRIA Fees Under PRIA, refunds for a portion of the registration service fee are provided following the withdrawal of a PRIA covered application and at the request of an applicant. These tables provide the information for each registering division. OPP IO 607
Interpretations of PRIA 3 Fee Categories 2015-07-17 2020-02-28 EPA 705-G-2020-0608 PRIA Fees This document includes the expanded information about PRIA fee categories. OPP IO 608
Interpretations of PRIA 4 Fee Categories 2019-01-01 2020-02-28 EPA 705-G-2020-2649 PRIA Fees These 19 documents provides interpretations associated with each PRIA 4 fee category. OPP IO 2649
Office of Pesticide Program Electronic Label (OPPEL) Pilot 2018-01-01 2020-02-28 EPA 705-G-2020-3596 OPPEL In an effort to make pesticide label information easier to find and the approval of pesticide labels more efficient, EPA is working with pesticide registrants to pilot an electronic label system. As part of the OPPEL pilot, nine pesticide registrants will be developing and submitting pesticide labels to EPA through a fully electronic system, instead of as paper or PDF files. OPP IO 3596
OPPEL Pilot Document Guides, including Vocabulary Guide Version 3 2018-09-29 2020-02-28 EPA 705-G-2020-3600 OPPEL These documents are being used to pilot the OPPEL process, in particular the model for constructing an OPPEL label. OPP IO 3600
Overview of PRIA Fee Reduction and Refund Formula 2019-01-01 2020-02-28 EPA 705-G-2020-2515 PRIA Information on how the Agency calculates registration service fee reductions and refunds under PRIA. OPP IO 2515
Paying PRIA Application Fees 2018-01-01 2020-02-28 EPA 705-G-2020-0602 PRIA Fees Describes how to the Agency review of a fee payment, how to submit payment for PRIA application, different methods of payment. OPP IO 602
PRIA Fee Waivers for Small Businesses 2014-03-04 2020-02-28 EPA 705-G-2020-2513 PRIA Information on PRIA fee waivers for small businesses OPP IO 2513
Small Business Certification Examples 2018-01-01 2020-02-28 EPA 705-G-2020-0598 PRIA Fees An example of a certification for small business. OPP IO 598
Structured Product Labeling (SPL) Draft Implementation Guide with Validation Procedures and User Guide  2018-01-01 2020-02-28 EPA 705-G-2020-3599 FIFRA; Labeling This document provides an introduction to the OPPEL Model, as well as guidance on how to extract pesticide information into the Structured Product Label (SPL) model for submission to EPA.  OPP IO 3599
Structured Product Labeling (SPL) User Guide (unabridged) 2018-02-05 2020-02-28 EPA 705-G-2020-3597 OPPEL The purpose of this document is to provide instructions on how to use the OPPEL Product Label (SPL) Builder. This document provides guidance on how to properly prepare a Product Label and/or Use Index document for submission to EPA. OPP IO 3597
Templates and Instructions for PRIA Fee Payments 2016-01-01 2020-02-28 EPA 705-G-2020-1284 PRIA Fees The documents on this page provide templates and instructions for bank transfer and wire payments of PRIA fees. OPP IO 1284
2020 Annual Pesticide Registration Maintenance Fees 2019-11-26 2020-02-28 EPA 705-G-2020-1098 Pesticide Registration All section 3 and section 24(c) registrations are subject to an annual maintenance fee described in FIFRA Section 4(i)(5). The amount of this fee varies from year to year depending on the authorizing legislation. Affected applicants will be contacted by mail with instructions for submitting the fee. The deadline for responding to the maintenance fee notification is Wednesday, January 15, 2020. The fee per product will vary from year to year as the fee is dependent upon the projected number of products for which registrants will pay this fee. The fee for 2020 is $4,000. Please note that checks, bank drafts and money orders are no longer an acceptable form of payment. OPP ITRMD 1098
Assembly of Electronic Packages and Discs 2013-05-03 2020-02-28 EPA 705-G-2020-0479 Pesticide Registration Methods for assembling electronic packages and creating submission discs OPP ITRMD 479
CDX Pesticide Submissions Portal (PSP) Registration User Guide 2016-02-12 2020-02-28 EPA 705-G-2020-2823 Pesticide Registration, CDX, PSP, pesticide submissions portal; central data exchange The purpose of this PDF document is to walk through the registration and user profile management processes in CDX, specifically for Pesticide Submission Portal (PSP) workflow submissions. OPP ITRMD 2823
Creating a PDF Version of Study Reports - General Specifications 2008-06-25 2020-02-28 EPA 705-G-2020-0563 Pesticide Registration This document lists software, layout, and other specifications for creating PDF versions of study reports for electronic submission for pesticide registration. OPP ITRMD 563
Critical PDF Label Specifications for Electronic Submission 2017-02-23 2020-02-28 EPA 705-G-2020-0498 Pesticide Registration; Electronic Submission Label Specifications Guidance information about electronic submission for critical PDF label specifications. OPP ITRMD 498
Data Compensation Documents 1984-08-01 2020-02-28 EPA 705-G-2020-1494 Pesticide Registration EPA does not have specific forms to use related to data compensation for inert ingredients. These documents will help the registrant with the process. OPP ITRMD 1494
Disclosure of Reviews of Pesticide Test Data 1985-11-27 2020-02-28 EPA 705-G-2020-1484 Pesticide Registration This document describes a class determination that certain EPA-prepared reviews of data submitted under the Federal insecticide, Fungicide, and Rodenticide Act are not entitled to confidential treatment. OPP ITRMD 1484
Electronic Submissions of Pesticide Applications 2019-08-19 2020-02-28 EPA 705-G-2020-2411 electronic submission; portal; PSP; application materials General Information about Electronic Submission of Pesticide Applications, application materials required and tools for developing an electronic submission. OPP ITRMD 2411
E-Submission Guidance Updates 2019-02-15 2020-02-28 EPA 705-G-2020-0493 Pesticide Registration; E-submission Guidance; Dossier-Formatted E-submission guidance updates for all e-submissions and Dossier formatted submissions. OPP ITRMD 493
E-submission Resource Documents for Assembly of Electronic Packages and Discs 2018-03-30 2020-02-28 EPA 705-G-2020-0487 Pesticide Registration; E-submission; Electronic Packages Learn more about submitting pesticide applications via the Pesticide Submission Portal. OPP ITRMD 487
Frequent Questions about Electronic Submission of Labels 2017-04-14 2020-02-28 EPA 705-G-2020-0499 Pesticide Registration; Electronic Label Submission FAQs Find information to help you with e-submission of labels. OPP ITRMD 499
Full Specifications for Text PDF Label Submissions 2008-01-17 2020-02-28 EPA 705-G-2020-0492 Pesticide Registration; Specifications Label Submissions The following guidance is provided for creating and submitting product labels in electronic format to EPA. Submission of electronic labels to EPA is voluntary, but if done then two specifications are mandatory. OPP ITRMD 492
How to Search for Information about Pesticide Ingredients and Labels 2014-01-06 2020-02-28 EPA 705-G-2020-0574 Ingredients Used in Pesticide Products How to use the databases Pesticide Chemical Search, Pesticide Product Label System (PPLS), and InertFinder to find information such as Chemical Abstract Service (CAS) numbers, active and inert ingredients, and regulatory actions. OPP ITRMD 574
National List of Active EPA-Registered Foreign and Domestic Pesticide and/or Device-Producing Establishments 2019-10-21 2020-02-28 EPA 705-G-2020-2456 Pesticide Registration; establishment This website contains guidance on updating establishments and includes a CSV file lists the most current non-Confidential Business Information (CBI) of active EPA-registered foreign and domestic pesticide-producing and device-producing establishments based on data from the Section Seven Tracking System (SSTS). OPP ITRMD 2456
Office of Pesticide Programs eDossier Builder User Guide 2015-08-27 2020-02-28 EPA 705-G-2020-2824 eSubmission; XML; eDossier; eDossier Builder The eDossier Builder system, developed by the Environmental Protection Agency (EPA) Office of Pesticide Programs (OPP), allows registrants to create packages for electronic submission in a user-friendly manner and presents packages to EPA systems in a specified format. OPP ITRMD 2824
Office of Pesticide Programs eSubmission XML Guidance Document 2015-08-26 2020-02-28 EPA 705-G-2020-2825 Pesticide Registration, eSubmission, XML The purpose of this PDF document is to provide registrants instructions for constructing an XML file for inclusion in an electronic submission package and submitting the documents to the Environmental Protection Agency (EPA) Office of Pesticide Programs (OPP) electronically on CD/DVD. OPP ITRMD 2825
Pesticide Product Label System (PPLS) Application Program Interface (API) 2016-06-20 2020-02-28 EPA 705-G-2020-1564 Pesticide Labels Pesticide Product Label System (PPLS) provides a single point of access to U.S. EPA environmental data contained in the U.S. EPA databases. OPP ITRMD 1564
Pesticide Submissions Portal (PSP) Frequently Asked Questions 2015-09-18 2020-02-28 EPA 705-G-2020-1448 Pesticide Registration Pesticide Submissions Portal (PSP) Frequently Asked Questions OPP ITRMD 1448
Pesticide Submissions Portal (PSP) User Guide 2018-03-28 2020-02-28 EPA 705-G-2020-2822 Pesticide Registration, CDX, PSP, pesticide submissions portal The purpose of this PDF document is to provide instructions on how to use the PSP application. This document provides guidance on how to properly prepare a package for submission to EPA. OPP ITRMD 2822
Study Formatting and Supplemental Information 2019-09-17 2020-02-28 EPA 705-G-2020-0481 Pesticide Registration; Study Formatting; Supplemental Information Information and guidance on e-submission study formatting and supplemental files and review aids. OPP ITRMD 481
Submitting EPA Form 3540-16 Through the SSTS CDX Application 2016-10-12 2020-02-28 EPA 705-G-2020-2836 3540-16 PDF for Submitting EPA Form 3540-16 Through the SSTS CDX Application OPP ITRMD 2836
Voluntary Incident Reporting Forms and Instructions 1998-08-04 2020-02-28 EPA 705-G-2020-1747 Reporting Pesticide Incidents Reporting forms that can be used by Registrants to report 6(a)(2) related incidents to the EPA. OPP ITRMD 1747
Enhancing Stakeholder Input in the Pesticide Registration Review and ESA Consultation Processes and Development of Economically and Technologically Feasible Reasonable and Prudent Alternatives 2013-03-19 2020-02-28 EPA 705-G-2020-3071 Endangered Species; Pesticides This document, which was developed jointly by the EPA, the U.S. Department of Agriculture (USDA), the National Marine Fisheries Service (NMFS) in the U.S. Department of Commerce and the Fish and Wildlife Service (USFWS) in the U.S. Department of Interior, provides guidance to staff and managers participating in the associated processes. OPP PRD 3071
Methyl Bromide Commodity Fumigation Buffer Zone Lookup Tables 2017-03-13 2020-02-28 EPA 705-G-2020-3054 Fumigants The labels of the products listed require that all applications must have a specified buffer zone around treatment and aeration areas. Buffer zone distances must be determined according to the tables and instructions listed. The applicable buffer zone is part of the directions for use of these products. OPP PRD 3054
Opportunities to Participate in Pesticide Reevaluation 2019-05-02 2020-02-28 EPA 705-G-2020-3075 Pesticides Web page providing information about the public participation process during registration review. OPP PRD 3075
Soil Fumigant Buffer Zone Calculator 2018-07-01 2020-02-28 EPA 705-G-2020-3052 Soil Fumigants Buffer zone calculator tool for applicators, growers, and enforcement personnel applying/monitoring soil fumigant applications. OPP PRD 3052
Soil Fumigant Toolbox 2018-07-10 2020-02-28 EPA 705-G-2020-3610 Soil Fumigants This website provides soil fumigant information on training, fumigant management plans, buffer zones, and other safety measures to ensure protections for agricultural workers and bystanders. OPP PRD 3610
Tarp Testing Guidance 2019-06-06 2020-02-28 EPA 705-G-2020-0561 Soil Fumigants Since the reactivity, stability, and other chemical properties are different for each soil fumigant pesticide, the permeability of each fumigant through a film will be different. Certain tarps that qualify for buffer zone reduction credits are listed. OPP PRD 561
About Pesticide Registration - Pesticide Registration 2019-06-26 2020-02-28 EPA 705-G-2020-2843 Pesticide Registration Describes the process for evaluating pesticide registration applications - human health and environmental risk considerations. OPP RD 2843
About Risk Assessment 2020-01-06 2020-02-28 EPA 705-G-2020-2975 Pesticide Risk Assessment Webpage containing information regarding risk assessment basics. OPP RD 2975
Accelerated Storage Stability and Corrosion Characteristics Study Protocol 2012-11-16 2020-02-28 EPA 705-G-2020-1490 Pesticide Registration; Accelerated Storage Stability Corrosion Characteristics EPA has determined that studies using this protocol will, in certain circumstances, provide the Agency with all the information it needs to make a determination on the storage stability of pesticides. OPP RD 1490
Acute Dermal Toxicity - [species] 2004-05-01 2020-02-28 EPA 705-G-2020-3330 Study Profile Template Study profile template for acute dermal toxicity study OPP RD 3330
Acute Inhalation Toxicity - [species] 2004-05-01 2020-02-28 EPA 705-G-2020-3331 Study Profile Template Study profile template for acute inhalation toxicity study OPP RD 3331
Acute Oral Toxicity - [species] 2004-05-01 2020-02-28 EPA 705-G-2020-3329 Study Profile Template Study profile template for acute oral toxicity study OPP RD 3329
Acute Oral Toxicity Up-And-Down-Procedure 2017-03-29 2020-02-28 EPA 705-G-2020-2416 acute oral toxicity; up and down; 870.1100 Provides information on the program and associated documentation for conducting the Up-and-Down Procedure, an alternative acute toxicity test that provides a way to determine the toxicity of chemicals with fewer test animals by using sequential dosing steps. OPP RD 2416
Application Submission and Screening 2016-08-22 2020-02-28 EPA 705-G-2020-2979 Pesticide Registration High-level overview page with links to various component checklists for pesticide registration application submissions. OPP RD 2979
Bridging or Waiving Data Requirements 2019-09-17 2020-02-28 EPA 705-G-2020-0513 Pesticide Registration; Bridging Data Requirements Pesticide registrants can request a waiver of data requirements or seek to bridge data from one data set to another. The documents below explain our approach to data waivers. OPP RD 513
Child-Resistant Packaging for Pesticides 2019-12-18 2020-02-28 EPA 705-G-2020-0596 Pesticide Registration; CRP To protect children from poisonings around the home, pesticide law requires that certain household pesticides be in child-resistant packaging. OPP RD 596
Controlling Rodents and Regulating Rodenticides 2018-07-10 2020-02-28 EPA 705-G-2020-2837 Rodents, Rodenticides, regulating Site with multiple links. OPP RD 2837
Conventional Pesticide Registration 2017-03-20 2020-02-28 EPA 705-G-2020-0413 Pesticide Registration; Conventional Conventional pesticides are all active ingredients other than biological pesticides and antimicrobial pesticides. Learn about the requirements and process for registering a conventional pesticide. OPP RD 413
Conventional Reduced Risk Pesticide Program 2019-09-14 2020-02-28 EPA 705-G-2020-0434 Pesticide Registration; Reduced Risk Find out about the Conventional Reduced Risk Pesticide Program, which expedites the review and regulatory decision-making process of conventional pesticides that pose less risk to human health and the environment than existing conventional alternatives. OPP RD 434
Crosswalk of Paragraphs: OPPTS 870.1100 versus OECD 425 Acute Oral Toxicity: Up-and-Down Procedure 2017-03-29 2020-02-28 EPA 705-G-2020-2863 acute oral toxicity; up and down; 870.1100; OECD 425 Guidance on relationship and cross-walk between OPPTS 870.1100 guideline and OECD 425 guideline. OPP RD 2863
Data Requirements for Pesticide Registration 2019-06-26 2020-02-28 EPA 705-G-2020-2894 Pesticide Registration - data Data Requirements to Register a Pesticide OPP RD 2894
Dermal Sensitization - [species] 2004-05-01 2020-02-28 EPA 705-G-2020-3334 Study Profile Template Study profile template for dermal sensitization study OPP RD 3334
Draft Waiver Guidance on Dermal Toxicity Testing: Retrospective Analysis and Guidance for Waiving Acute Dermal Toxicity Tests for Pesticide Formulations 2016-03-11 2020-02-28 EPA 705-G-2020-2854 Pesticide Registration; toxicity testing; waiving This page provides a link to guidance for waiving dermal toxicity data. OPP RD 2854
Elements of an Offer to Pay for the Use of Inert Ingredient Data 2019-10-17 2020-02-28 EPA 705-G-2020-2865 Data Compensation Inert Ingredient This link offers guidance on elements that should be included in an Offer to Pay for the use of Inert ingredient data. OPP RD 2865
Enhanced Incident Reporting Template (XLSX) 2017-03-01 2020-02-28 EPA 705-G-2020-2872 Enhanced reporting, adverse incident, pet spot-on EPA's standardized template for submission of enhanced reporting for adverse incidents OPP RD 2872
EPA Actions to Protect Pollinators 2017-10-23 2020-02-28 EPA 705-G-2020-2507 Pollinator Protection This page contains a summary of EPA's actions to protect pollinators from pesticide exposure. OPP RD 2507
EPA Evaluation of Pet Spot-on Products: Analysis and Plans for Reducing Harmful Effects 2019-08-08 2020-02-28 EPA 705-G-2020-2436 pet spot-on; analysis Provides information on the EPA Evaluation of Pet Spot-on Products, the Analysis and Plans for Reducing Harmful Effects. It also includes links to enhanced reporting templates. OPP RD 2436
EPA Response to letter dated August 31, 2018, regarding disruptions in availability of 1,2-benzisothiazolin-3-one (BIT) and the self-certification process. 2018-10-18 2020-02-28 EPA 705-G-2020-2498 Pesticide Registration; BIT self-certification This letter is in response to a registrant letter requesting the incorporation of further clarifications and additions to EPA’s August 23, 2018, letter addressing disruptions in availability of 1,2 benzisothiazolin-3-one (BIT) and providing for a streamlined self-certification process. OPP RD 2498
First Aid Guidance Document – EPA’s Guidance for Pesticide Registrants on Location of the First Aid Statement per 40 CFR 156.68. (Docket ID: EPA-HQ-OPP-2016-0545) 2018-03-07 2020-02-28 EPA 705-G-2020-2963 First Aid Statements; Pesticide Labeling This document summarizes the EPA's decision regarding the interpretation of the term “panel” in the context of 40 CFR 156.68 and includes a clarification regarding where first aid statements must appear on pesticide labels based on the product’s Toxicity Category. OPP RD 2963
First Aid Guidance: Response to Public Comments on EPA’s Guidance for Pesticide Registrants on Location of the First Aid Statement and Clarification on Definition of Label “Panel” per 40 CFR 156.68. (Docket ID: EPA-HQ-OPP-2016-0545) 2018-03-07 2020-02-28 EPA 705-G-2020-2964 First Aid Statements; Pesticide Labeling This document summarizes the EPA's response to public comments on its memorandum to clarify the interpretation of the term “panel” in the context of 40 CFR 156.68 and to clarify where first aid statements must appear on pesticide labels based on the product’s Toxicity Category. OPP RD 2964
Food and Pesticides 2019-03-06 2020-02-28 EPA 705-G-2020-2994 Pesticide Registration Page includes information about pesticides on food and how this is regulated; it includes links to related guidance. OPP RD 2994
Formulation / End-use Product - Product Chemistry Evaluation (based on OECD Dossier Numbering) Identity, Physical and Chemical Properties, Analytical Methods, Confidential Information 2016-05-01 2020-02-28 EPA 705-G-2020-2916 Pesticide registration, product chemistry The study profile template describes the layout and scope of information that should be contained within a study profile and can serve as a guide for the preparation of the study document. OPP RD 2916
General Guidance for Petitioning the Agency for the Establishment of a New/Amended Food Use Inert Ingredient Tolerance or Tolerance Exemption under PRIA 3 2013-01-08 2020-02-28 EPA 705-G-2020-2923 Pesticide Registration Guidance for new/amended food use inert ingredient tolerance or tolerance exemption OPP RD 2923
General Guidance for Requesting the Approval of a New Nonfood Use Inert Ingredient1 or Amending a Currently Approved Nonfood Use Inert Ingredient under PRIA 3 2013-01-23 2020-02-28 EPA 705-G-2020-2925 Pesticide Registration Guidance for requesting the approval of a new nonfood use inert ingredient or amending a currently approved nonfood use inert ingredient OPP RD 2925
General Guidance for Requesting the Establishment of a Tolerance Exemption for a Low Risk Polymer or Nonfood Use Approval of a Low Risk Polymer under PRIA 3 2013-01-23 2020-02-28 EPA 705-G-2020-2924 Pesticide Registration Guidance for establishing tolerance exemption for low risk polymer or nonfood use approval of low risk polymers OPP RD 2924
Guidance for Identifying, Selecting and Evaluating Open Literature Studies 2017-10-03 2020-02-28 EPA 705-G-2020-2815 Pesticide Registration; literature evaluation; risk assessment This is a web page providing guidance on how to evaluate open literature data to support pesticide applications, and also how EPA itself evaluates open literature for use in the risk assessment process. OPP RD 2815
Guidance for Pesticide Registrants on Location of the First Aid Statement and Clarification on Definition of Label "Panel" per 40 CFR 156.68 2016-12-07 2020-02-28 EPA 705-G-2020-2961 First Aid Statement; Pesticide Labeling Clarification memo on the Agency's interpretation of the word "panel" in the context of 40 CFR 156.68 including where First Aid statements must appear on a product's label based on the product's toxicity category. OPP RD 2961
Guidance on Efficacy Testing for Pesticides Targeting Certain Invertebrate Pests 2019-12-13 2020-02-28 EPA 705-G-2020-1507 Pesticide Registration; Efficacy Testing; Claims; Invertebrate Pests This page is intended to help pesticide registrants complete the efficacy requirements related to invertebrate pests that may damage structures or pose significant risks to public health. OPP RD 1507
Guidance on FIFRA 24(c) Registrations 2019-06-07 2020-02-28 EPA 705-G-2020-2424 24(c); state registration EPA guidance (including Q&A) on registering 24(c) (Special Local Needs) registrations. OPP RD 2424
Guidance on IR-4 Exemptions 2019-03-29 2020-02-28 EPA 705-G-2020-0597 PRIA Fees; IR-4 Exemptions Information and guidance about inter-regional project 4 (IR-4) registration fee exemptions. OPP RD 597
Guidance on Placement of First Aid Statements on Pesticide Labels 2018-03-08 2020-02-28 EPA 705-G-2020-2419 first aid; label In response to comments from states and pesticide registrants, EPA is releasing final guidance clarifying where first aid statements should appear on the label of pesticide products. OPP RD 2419
Guiding Principles for Data Requirements 2013-05-31 2020-02-28 EPA 705-G-2020-2803 Pesticide Registration; data requirements PDF that summarizes how/why EPA exercises its authority to require certain data it deems necessary to support regulatory decisions OPP RD 2803
How to Search for Tolerances for Pesticide Ingredients in the Code of Federal Regulations 2018-04-02 2020-02-28 EPA 705-G-2020-2794 Pesticide Registration; tolerances; MRLs This page provides instructions and links to searching for tolerances. OPP RD 2794
Implementation Guidance for Enhanced Reporting for Registrants of Pet Spot-on Products 2019-08-07 2020-02-28 EPA 705-G-2020-2435 pet spot-on; incident reporting template Links to the documents that provide background and summary information on the pet spot-on enhanced reporting pilot and guidance for implementing the use of standardized incident reporting templates. OPP RD 2435
Indexes to Part 180 Tolerance Information for Pesticide Chemicals in Food and Feed Commodities 2017-05-23 2020-02-28 EPA 705-G-2020-2976 Pesticide Tolerances Webpage describing information that may be helpful in finding specific pesticide tolerance information available in the CFR at Part 180. OPP RD 2976
Inert Ingredient Frequently Asked Questions 2015-12-01 2020-02-28 EPA 705-G-2020-2937 Pesticide registration, inerts This document answers frequently asked questions about inert ingredients OPP RD 2937
Inert Ingredients Overview and Guidance 2020-01-30 2020-02-28 EPA 705-G-2020-0444 Pesticide Registration; FIFRA; Pesticides; Antimicrobial; This Web page provides information on inert ingredients approved for use in pesticide products and the guidance documents that are available to assist in obtaining approval for a new inert ingredient. OPP RD 444
Inert Use Information | InertFinder | Pesticides | US EPA 2020-01-21 2020-02-28 EPA 705-G-2020-2412 inert; CAS; food; nonfood; fragrance; InertFinder is an online database for searching substances used as inert ingredients in pesticide products. OPP RD 2412
Ingredients Used in Pesticide Products 2019-04-30 2020-02-28 EPA 705-G-2020-2986 Pesticide Registration Links to pesticide information, groups, inerts, and databases. OPP RD 2986
Label Guidance for Specific Types of Pesticides 2017-10-23 2020-02-28 EPA 705-G-2020-2444 warranty; repellents; antimicrobials;  Guidance on label contents as needed to clarify issues or implement program changes OPP RD 2444
Label Review Manual 2019-05-09 2020-02-28 EPA 705-G-2020-0470 Pesticide Registration; Label Review Manual Table of Contents for Label Review Manual OPP RD 470
Label Review Manual Chapter 10; Revised Respirator Descriptions for Public Comment 2018-04-12 2020-02-28 EPA 705-G-2020-1734 Pesticide Registration; Label Review Manual Revised Respirator Descriptions for Public Comment Documents OPP RD 1734
Label Review Manual, Chapter 1: Purpose of the Manual 2016-12-01 2020-02-28 EPA 705-G-2020-2941 Pesticide Registration This chapter describes the purpose of the Label Review Manual. OPP RD 2941
Label Review Manual, Chapter 10: Worker Protection Label 2016-02-01 2020-02-28 EPA 705-G-2020-2950 Pesticide Registration; Pesticide Labeling This chapter describes worker protection labeling. OPP RD 2950
Label Review Manual, Chapter 11: Directions for Use 2014-12-01 2020-02-28 EPA 705-G-2020-2951 Pesticide Registration; Pesticide Labeling This chapter describes the directions for use section of the label. OPP RD 2951
Label Review Manual, Chapter 12: Labeling Claims 2013-11-01 2020-02-28 EPA 705-G-2020-2952 Pesticide Registration; Pesticide Labeling This chapter discusses claims made on labels. OPP RD 2952
Label Review Manual, Chapter 13: Storage and Disposal 2013-07-01 2020-02-28 EPA 705-G-2020-2953 Pesticide Registration; Pesticide Labeling This chapter describes the storage and disposal section of the label. OPP RD 2953
Label Review Manual, Chapter 14: Identification Numbers 2012-11-01 2020-02-28 EPA 705-G-2020-2954 Pesticide Registration; Pesticide Labeling This chapter describes identification numbers on labels. OPP RD 2954
Label Review Manual, Chapter 15: Company Name and Address 2017-08-01 2020-02-28 EPA 705-G-2020-2955 Pesticide Registration; Pesticide Labeling This chapter describes listing the company name and number on the label. OPP RD 2955
Label Review Manual, Chapter 16: Graphics and Symbols 2017-08-01 2020-02-28 EPA 705-G-2020-2956 Pesticide Registration; Pesticide Labeling This chapter describes graphics and logos listed on labels. OPP RD 2956
Label Review Manual, Chapter 17: Net Contents/Net Weight 2018-02-01 2020-02-28 EPA 705-G-2020-2957 Pesticide Registration; Pesticide Labeling This chapter describes the net contents and net weight located on the label. OPP RD 2957
Label Review Manual, Chapter 18: Unique Product Labeling 2013-09-01 2020-02-28 EPA 705-G-2020-2958 Pesticide Registration; Pesticide Labeling This chapter describes unique product labeling. OPP RD 2958
Label Review Manual, Chapter 2: What is a Pesticide? 2021-01-19 2021-01-19 EPA 705-G-2020-2942 Pesticide Registration

This chapter describes what a pesticide is.

Note: This guidance document was original published on 3/1/1998, and updated on 1/19/2021. The original guidance document was included in the 2/28/2020 version of the OCSPP guidance list.

OPP RD 2942
Label Review Manual, Chapter 3: General Labeling Requirements 2018-03-01 2020-02-28 EPA 705-G-2020-2943 Pesticide Registration This chapter describes general labeling requirements. OPP RD 2943
Label Review Manual, Chapter 4: Types of Label Reviews 2011-12-01 2020-02-28 EPA 705-G-2020-2944 Pesticide Registration This chapter describes types of label reviews. OPP RD 2944
Label Review Manual, Chapter 5: Ingredient Statements 2012-03-01 2020-02-28 EPA 705-G-2020-2945 Pesticide Registration This chapter describes the ingredient statement on the pesticide label. OPP RD 2945
Label Review Manual, Chapter 6: Use Classification 2012-01-01 2020-02-28 EPA 705-G-2020-2946 Pesticide Registration This chapter describes the use classifications on the label. OPP RD 2946
Label Review Manual, Chapter 7: Precautionary Statements 2018-03-01 2020-02-28 EPA 705-G-2020-2947 Pesticide Registration This chapter describes the precautionary statements on the label. OPP RD 2947
Label Review Manual, Chapter 8: Environmental Hazards 2012-09-01 2020-02-28 EPA 705-G-2020-2948 Pesticide Registration This chapter describes the environmental hazards section on the label. OPP RD 2948
Label Review Manual, Chapter 9: Physical or Chemical Hazards 2012-09-01 2020-02-28 EPA 705-G-2020-2949 Pesticide Registration; Pesticide Labeling This chapter describes the physical or chemical hazards section on the label. OPP RD 2949
List of Trade Name Inert Ingredients 2014-02-05 2020-02-28 EPA 705-G-2020-2927 Pesticide Registration EPA’s Office of Pesticide Programs (OPP) has developed a list of trade names for inert ingredients used pesticide products registered under FIFRA. OPP RD 2927
Logos and Graphics on Pesticide Product Labels 2019-05-21 2020-02-28 EPA 705-G-2020-2445 logo; label Guidance for applying to add a logo to a product label. OPP RD 2445
Meetings with Manufacturers of Pet Spot-on Products 2009-01-01 2020-02-28 EPA 705-G-2020-2874 Pet spot-on, mitigation, adverse effect, adverse incident, dog, cat Web page includes sections: Summary of Meetings we held with the Product Registrants; Generic mitigation table provided to product registrants; next steps. OPP RD 2874
Method for testing ready-to-use bait stations with adults for facility of opening, reclosing, and securing 1987-10-29 2020-02-28 EPA 705-G-2020-2469 Pesticide Registration; bait This protocol is designed to test the reliability with which untrained adults can perform tasks necessary for proper use of ready-to-use bait stations. OPP RD 2469
Method for testing ready-to-use bait stations with young children 1987-10-29 2020-02-28 EPA 705-G-2020-2470 Pesticide Registration; bait This protocol is designed to test the abilities of ready-to-use bait stations to isolate bait from children of pre-school age. OPP RD 2470
Method for testing ready-to-use consumer bait stations with dogs 2009-05-20 2020-02-28 EPA 705-G-2020-2468 Pesticide Registration; bait This protocol is designed to test the abilities of ready-to-use bait stations to isolate bait from dogs. OPP RD 2468
Minor revisions to “First Aid Guidance Document – EPA’s Guidance for Pesticide Registrants on Location of the First Aid Statement per 40 CFR 156.68” and Response to Public Comments 2018-03-07 2020-02-28 EPA 705-G-2020-2965 First Aid Statement; Pesticide Labeling The purpose of this note is to clarify minor changes made to the documents titled “First Aid Guidance Document – EPA’s Guidance for Pesticide Registrants on Location of the First Aid Statement per 40 CFR 156.68” and “First Aid Guidance: Response to Public Comments on EPA’s Guidance for Pesticide Registrants on Location of the First Aid Statement and Clarification on Definition of Label “Panel” per 40 CFR 156.68” located in docket EPA-HQ-OPP-2016-0545 on www.regulations.gov. OPP RD 2965
Minor Uses and Grower Resources 2019-08-02 2020-02-28 EPA 705-G-2020-2848 exclusive use; minor use Provides information on Minor Use Crops and Pesticides, International MRLs, NAFTA Minor Use Joint Reviews, Crop Grouping, Exclusive Use Periods, Definition of a Minor Use, Establishing or Extending Exclusive Use Periods. OPP RD 2848
Non-Animal Testing Approach to EPA Labeling for Eye Irritation 2017-05-03 2020-02-28 EPA 705-G-2020-2806 Pesticide Registration; non-animal testing; eye irritation This is a webpage describing alternative in vitro/ex vivo assays for the eye irritation test OPP RD 2806
Notifying the Public about Pesticide Tolerances 2017-02-09 2020-02-28 EPA 705-G-2020-2789 Pesticide Registration; tolerances; notice to public This page includes summary information about a notice of filing of a petition to establish a tolerance, emergency exemptions, establishing tolerances and exemptions, revoking tolerances, and tolerance objections. OPP RD 2789
OECD Guideline for Testing of Chemicals 2001-12-17 2020-02-28 EPA 705-G-2020-2860 acute oral toxicity; up and down; 870.1100; OECD 425 Guidance providing information and descriptions on the OECD Test Guideline 425, how to perform the studies and what data needs to be submitted. OPP RD 2860
Pest Control Devices and Device Producers: 1976 Federal Register Notice 1976-11-19 2020-02-28 EPA 705-G-2020-1295 Pesticide Registration Consolidation and clarification of requirements for pesticide devices. OPP RD 1295
Pesticide Cancellation Under EPA's Own Initiative 2018-11-07 2020-02-28 EPA 705-G-2020-2790 Pesticide Registration; tolerances; cancellation Cancellation of a pesticide registration may be initiated by EPA after the Agency has evaluated the potential risks and benefits associated with registered uses of a pesticide.  This page describes steps leading to cancellation. OPP RD 2790
Pesticide Emergency Exemptions 2019-11-07 2020-02-28 EPA 705-G-2020-2845 Pesticide Registration; evaluation criteria; emergency exemptions Provides details on types and evaluation criteria for emergency exemptions. OPP RD 2845
Pesticide Labeling Questions & Answers 2019-10-21 2020-02-28 EPA 705-G-2020-1260 Pesticide Labels; Q & A Pesticide manufacturers, applicators, state regulatory agencies, and other stakeholders raise questions or issues about pesticide labels. The questions on this page are those that apply to multiple products or address inconsistencies among product labels. OPP RD 1260
Pesticide Labels: Guidance on Warranty Statements  2016-10-16 2020-02-28 EPA 705-G-2020-2453 warranty; label This guidance includes examples of improper warranty statements that go beyond what the agency considers acceptable and examples of how to fix these statements, in addition to examples of statements that are acceptable under FIFRA, and that could be incorporated into FIFRA labels. OPP RD 2453
Pesticide Registration 2019-12-19 2020-02-28 EPA 705-G-2020-0411 Pesticide Registration This site provides resources for an individual or company wanting to register a pesticide active ingredient or pesticide product in the United States. Features: a manual (blue book), other guidance, and coordinated lists of requirements by pesticide type. OPP RD 411
Pesticide Registration Manual 2017-04-20 2020-02-28 EPA 705-G-2020-0412 Pesticide Registration Manual; Describes the pesticide registration process for companies and individuals wanting to register their pesticide product. OPP RD 412
Pesticide Registration Manual: Appendix A - Guidance Documents 2017-03-13 2020-02-28 EPA 705-G-2020-0526 Pesticide Registration Manual Find links to EPA guidance documents supporting the pesticide registration process. OPP RD 526
Pesticide Registration Manual: Appendix B - Examples of Registrant Documents 2017-08-31 2020-02-28 EPA 705-G-2020-0524 Pesticide Registration Manual Examples of Registrant Documents OPP RD 524
Pesticide Registration Manual: Appendix C - Pesticide Forms Overview Table 2016-11-05 2020-02-28 EPA 705-G-2020-0525 Pesticide Registration Manual; Pesticide Forms This chapter provides listings of the forms that are required when applying for a pesticide product, experimental use permit, and distributor registrations OPP RD 525
Pesticide Registration Manual: Appendix D - Examples of Completed Forms 2020-01-07 2020-02-28 EPA 705-G-2020-0529 Pesticide Registration Manual; Examples View examples of completed pesticide registration forms. OPP RD 529
Pesticide Registration Manual: Blank Forms 2020-01-07 2020-02-28 EPA 705-G-2020-0542 Pesticide Registration Manual; Forms These forms are to be used by applicants for pesticide registration. OPP RD 542
Pesticide Registration Manual: Chapter 1 - Overview of Requirements for Pesticide Registration and Registrant Obligations 2019-11-21 2020-02-28 EPA 705-G-2020-0484 Pesticide Registration Manual; Overview of Requirements; Registrant Obligations This chapter provides an overview of the federal laws under the authority of which EPA oversees pesticide use in the U.S. OPP RD 484
Pesticide Registration Manual: Chapter 10 - Data Compensation Requirements 2017-05-24 2020-02-28 EPA 705-G-2020-0509 Pesticide Registration Manual; Data Compensation; Requirements This chapter provides information about data compensation requirements, procedures, and obligations when submitting an application for registration, amended registration, reregistration or registration review. OPP RD 509
Pesticide Registration Manual: Chapter 11 - Tolerance Petitions 2018-04-02 2020-02-28 EPA 705-G-2020-0510 Pesticide Registration Manual; Tolerance Petitions This Chapter provides information on definitions, interpretative regulations and procedures for filing a petition for establishment of a tolerance or an exemption from the requirement of a tolerance. OPP RD 510
Pesticide Registration Manual: Chapter 12 - Applying for an Experimental Use Permit 2017-05-23 2020-02-28 EPA 705-G-2020-0511 Pesticide Registration Manual; Experimental Use Permit This chapter of the pesticide registration manual describes the all requirements for Experimental Use Permits (EUP), and includes how to apply for an EUP, labeling requirements, application format, and data reporting requirements. OPP RD 511
Pesticide Registration Manual: Chapter 13 - Devices 2017-05-24 2020-02-28 EPA 705-G-2020-0512 Pesticide Registration Manual; Devices This chapter describes how EPA regulates pesticidal devices. OPP RD 512
Pesticide Registration Manual: Chapter 14 - How to Obtain an EPA Company or Establishment Number or Change Address or Contact Information 2019-10-03 2020-02-28 EPA 705-G-2020-0514 Pesticide Registration; Manual; EPA Company or Establishment Number This chapter provides information on how to get an establishment number for pesticide registration applicants OPP RD 514
Pesticide Registration Manual: Chapter 15 - Submitting Data and Confidential Business Information 2017-05-24 2020-02-28 EPA 705-G-2020-0515 Pesticide Registration Manual; Submitting; Confidential Business Information This chapter includes information on how to submit data as well as special considerations concerning what data and information can be considered to be confidential business information. OPP RD 515
Pesticide Registration Manual: Chapter 16 - Transfer of Product Registrations and Data Rights 2020-01-15 2020-02-28 EPA 705-G-2020-0518 Pesticide Registration Manual; Transfer of Products; Data Rights This chapter discusses specific information to be submitted to EPA for the transfer of product registration and/or data rights from one person or company to another. OPP RD 518
Pesticide Registration Manual: Chapter 17 - State Regulatory Authority 2019-07-29 2020-02-28 EPA 705-G-2020-0519 Pesticide Registration Manual; State Authority FIFRA authorizes states to issue Experimental Use Permits, Special Local Needs registrations, and to apply for Emergency Exemptions under specific conditions. This chapter provides detailed information relevant to state actions under FIFRA. OPP RD 519
Pesticide Registration Manual: Chapter 18 - Other Federal or State Agency Requirements 2019-07-29 2020-02-28 EPA 705-G-2020-0520 Pesticide Registration Manual; Other Federal Requirements; State Agency Requirements This chapter provides information that a pesticide registrant may need know in order to meet other federal, state, or local requirements after the registrant has obtained a federal registration. OPP RD 520
Pesticide Registration Manual: Chapter 19 - How to Obtain Publications 2018-12-18 2020-02-28 EPA 705-G-2020-0521 Pesticide Registration Manual; Obtaining Publications This chapter provides information on how and where to obtain publications. OPP RD 521
Pesticide Registration Manual: Chapter 2 - Registering a Pesticide Product 2017-12-20 2020-02-28 EPA 705-G-2020-0491 Pesticide Registration Manual; Guidance Registering Pesticide Product; Examples This chapter discusses what information is required to be submitted to EPA when applying for a pesticide product registration and the process for reviewing the applications. OPP RD 491
Pesticide Registration Manual: Chapter 20 - Forms and How to Obtain Them 2017-02-28 2020-02-28 EPA 705-G-2020-0522 Pesticide Registration Manual; Forms This chapter provides listings of the forms that are required when applying for a pesticide product, experimental use permit, and distributor registrations. OPP RD 522
Pesticide Registration Manual: Chapter 21 - Directions for Submitting Applications and Contacting EPA 2018-04-02 2020-02-28 EPA 705-G-2020-0523 Pesticide Registration Manual; Submitting Applications This chapter provides directions for submitting application information to the EPA pesticide program. OPP RD 523
Pesticide Registration Manual: Chapter 5 - Registration Fees 2018-04-02 2020-02-28 EPA 705-G-2020-0504 Pesticide Registration Manual; Registration Fees Information about pesticide registration fees according to the Pesticide Registration Improvement Extension Act (PRIA 3) OPP RD 504
Pesticide Registration Manual: Chapter 6 - Amending a Registered Pesticide Product 2017-08-30 2020-02-28 EPA 705-G-2020-0505 Pesticide Registration Manual; Amending Product Registration This chapter covers all aspects of amending a registered product including label changes, formulation changes, associated data requirements, and the forms that need to be submitted. OPP RD 505
Pesticide Registration Manual: Chapter 7 - Notifications and Minor Formulation Amendments 2017-08-02 2020-02-28 EPA 705-G-2020-0506 Pesticide Registration Manual; Notifications; Minor Formulation Amendments This chapter provides information about preparing and submitting a notification for a pesticide product OPP RD 506
Pesticide Registration Manual: Chapter 8 - Inert Ingredients 2017-05-24 2020-02-28 EPA 705-G-2020-0507 Pesticide Registration Manual; Inert Ingredients This chapter describes how EPA reviews inert ingredients as part of the pesticide product review process. OPP RD 507
Pesticide Registration Manual: Chapter 8 - Inert Ingredients 2017-05-24 2020-02-28 EPA 705-G-2020-2940 Pesticide Registration This chapter describes how EPA reviews inert ingredients as part of the pesticide product review process. OPP RD 2940
Pesticide Registration Manual: Chapter 9 - Supplemental Distribution of a Registered Pesticide 2017-07-13 2020-02-28 EPA 705-G-2020-0508 Pesticide Registration Manual; Supplemental Distribution This chapter provides information about the supplemental distribution of a registered pesticide or product. OPP RD 508
Pesticide Registration Manual: Confidential Statement of Formula Documents 2012-09-11 2020-02-28 EPA 705-G-2020-0545 Pesticide Registration; Confidential Statement of Formula; Attachment These documents will help you complete the confidential statement of formula for pesticides registrations. OPP RD 545
Pesticide Registration Manual: Example Good Laboratory Practice Statements 2016-11-05 2020-02-28 EPA 705-G-2020-0551 Pesticide Registration Manual; GLP Example statements related to the GLP standard. OPP RD 551
Pesticide Registration Manual: Example Letter for Registration or Amendment Applications Document 2016-11-07 2020-02-28 EPA 705-G-2020-1620 Pesticide Registration Manual; Examples Letter for Registration This example letter can be used in submitting pesticide registration or amendment applications. OPP RD 1620
Pesticide Registration Manual: Example Transmittal Document 2016-11-05 2020-02-28 EPA 705-G-2020-0549 Pesticide Registration Manual; Transmittal Document This example can be used in setting up a transmittal document for a pesticide registration package. OPP RD 549
Pesticide Registration Manual: How to Obtain a Company Number and Register an Official Address 2019-03-19 2020-02-28 EPA 705-G-2020-0547 Pesticide Registration; Company Number; Company Address Registrants must obtain a company number before registering their first product with the Agency. Registrants or others who plan to “produce” pesticides or devices must obtain the company number first, then submit EPA Form 3540-8. Find out how to do this. OPP RD 547
Pesticide Registration Manual: How to Report Changes to Company Name or Address 2019-03-27 2020-02-28 EPA 705-G-2020-0554 Pesticide Registration Manual; Report Changes Address and Company Name Any changes to the official address, withdrawal of an existing agent, appointment of a new agent or changes to any of the contact information for the company or its agent must be reported to EPA. Find out more about how to do this. OPP RD 554
Pesticide Registration Manual: Introduction 2018-04-02 2020-02-28 EPA 705-G-2020-0483 Pesticide Registration Manual This manual is intended as a resource for companies and individuals who wish to have their pesticide products registered by EPA. This introduction gives an overview of the contents of the manual. OPP RD 483
Pesticide Registration Manual: List of Data Submitters Sent Offer to Pay Letters 2016-11-05 2020-02-28 EPA 705-G-2020-0548 Pesticide Registration Manual; Data Submitter's List Sample format for providing the list of data submitters to whom you sent offer to pay letters. OPP RD 548
Pesticide Registration Manual: Product Chemistry 2017-02-21 2020-02-28 EPA 705-G-2020-0546 Pesticide Registration; Product Chemistry These documents will help you avoid common mistakes in completing the product chemistry aspect of the pesticide registration form. OPP RD 546
Pesticide Registration Manual: Registrant Summary of Pesticide Petitions for EPA's Notice of Filing 2011-10-01 2020-02-28 EPA 705-G-2020-0530 Pesticide Registration Manual; Electronic Submission Provides a company with information to electronically prepare and submit a pesticide tolerance petition to EPA. OPP RD 530
Pesticide Registration Manual: Stickers For Submitted Studies - Example 2016-11-04 2020-02-28 EPA 705-G-2020-0552 Pesticide Registration Manual; Submitted Studies Information to provide on pesticide studies submitted to EPA. OPP RD 552
Pesticide Registration Manual: Title Page For a Newly Submitted Study 2017-07-03 2020-02-28 EPA 705-G-2020-0550 Pesticide Registration Manual; Title Page Certain information should be included on the title page of a study submitted to EPA in support of pesticide registration. See a template for these elements. OPP RD 550
Pesticide Registration Policy and Guidance 2018-04-10 2020-02-28 EPA 705-G-2020-2849 Pesticide Registration; toxicity testing; human; human studies This page lists toxicity testing topics and guidance, protection of human test subjects, additional guidance and policy information. OPP RD 2849
Pesticide Use Site Index 2016-12-06 2020-02-28 EPA 705-G-2020-0595 Pesticide Registration; Pesticide Use Site; Index This Pesticide Use Site Index will help a company (or other applicant) identify which data requirements are needed to register a pesticide product. OPP RD 595
Pet Spot-on Enhanced Reporting Implementation Guidance (PDF) 2018-02-01 2020-02-28 EPA 705-G-2020-2870 Standardized Templates, Enhanced Reporting, Incident, Sales, Mitigation, Implementation; Conditions of Registration, expiration PDF of Guidance to use EPA's Standardized Incident and Sales Templates for enhanced reporting of adverse incidents and requesting changes to conditions of registration (Quarterly to Annual submission of enhanced reporting; Removal of 2-year expiration date); Webinar took place 5/10/2018; PDF first dated February 2018 and updated August 2019 OPP RD 2870
Policy on Existing Stocks of Pesticide Products 1991-06-26 2020-02-28 EPA 705-G-2020-1259 Pesticide Labels; Existing Stocks This statement establishes general principles the Agency generally will apply in determining whether and under what conditions to allow the sale and use of existing stocks of pesticides for which the registration has been amended, canceled, or suspended. OPP RD 1259
Primary Dermal Irritation - [species] 2004-05-01 2020-02-28 EPA 705-G-2020-3333 Study Profile Template Study profile template for primary dermal irritation study OPP RD 3333
Primary Eye Irritation - [species] 2004-05-01 2020-02-28 EPA 705-G-2020-3332 Study Profile Template Study profile template for primary eye irritation study OPP RD 3332
Process for Evaluating & Implementing Alternative Approaches to Traditional in Vivo Acute Toxicity Studies for FIFRA Regulatory Use 2016-02-04 2020-02-28 EPA 705-G-2020-1393 Pesticide Science and Assessing Pesticide Risks; Alternative Approaches in Vivo Acute Toxicity EPA’s Office of Pesticide Programs (OPP) has developed a strategic vision1 for implementing the 2007 NRC report on Toxicity Testing in the 21st Century. OPP RD 1393
Product Chemistry for End Use Products 2006-05-01 2020-02-28 EPA 705-G-2020-3293 product chemistry Template for product chemistry of end use products OPP RD 3293
Product Chemistry for Technical Grade of the Active Ingredient or Manufacturing Use Products (Group A and B data) 2016-05-01 2020-02-28 EPA 705-G-2020-3292 Study Profile Template Study profile template for product chemistry evaluation OPP RD 3292
Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3000, General Considerations for Efficacy of Invertebrate Control Agents 1998-03-01 2020-02-28 EPA 712-C-98-409 Test Guideline; Product Performance This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 60
Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, OCSPP 810.3100, Treatments for Imported Fire Ants 2021-01-19 2021-01-19 EPA 712-C-98-410 Test Guideline; Product Performance

This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

Note: This guidance document was original published on 3/1/1998, and updated on 1/19/2021. The original guidance document was included in the 2/28/2020 version of the OCSPP guidance list.

OPP RD 61
Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3200, Livestock, Poultry, Fur- and Wool-bearing Animal Treatments 1998-03-01 2020-02-28 EPA 712-C-98-414 Test Guideline; Product Performance This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 62
Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, OCSPP 810.3300, The Efficacy of Topically Applied Pet Products Against Certain Invertebrate Pests 2021-01-19 2021-01-19 EPA 712-C-98-411 Test Guideline; Product Performance

This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

Note: This guidance document was original published on 3/1/1998, and updated on 1/19/2021. The original guidance document was included in the 2/28/2020 version of the OCSPP guidance list.

OPP RD 63
Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3400, Mosquito, Black Fly, and Biting Midge (Sand Fly) Treatments 1998-03-01 2020-02-28 EPA 712-C-98-419 Test Guideline; Product Performance This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 64
Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3500, Premises Treatments 2019-08-28 2020-02-28 EPA 712-C-19-001 Test Guideline; Product Performance This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 65
Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3600, Structural Treatments 1998-03-01 2020-02-28 EPA 712-C-98-424 Test Guideline; Product Performance This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 66
Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3700, Insect Repellents to be Applied to Human Skin 2010-07-07 2020-02-28 EPA 712-C-10-001 Test Guideline; Product Performance This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 67
Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3800, Methods for Efficacy Testing of Termite Baits 2004-08-01 2020-02-28 EPA 712-C-04-371 Test Guideline; Product Performance This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 68
Product Performance Test Guidelines: Invertebrate Control Agent Product Performance Test Guidelines, 810.3900, Laboratory Product Performance Testing Methods for Bed Bug Pesticide Products 2017-06-01 2020-02-28 EPA 712-C-17-001 Test Guideline; Product Performance This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 69
Product Properties Test Guidelines: 830.1000, Background for Product Properties Test Guidelines 1998-03-01 2020-02-28 EPA 712-C-96-310 Test Guideline; Product Properties; Background This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 104
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6302, Color 1996-08-01 2020-02-28 EPA 712-C-96-019 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 79
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6303, Physical State 1996-08-01 2020-02-28 EPA 712-C-96-020 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 80
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6304, Odor 1996-08-01 2020-02-28 EPA 712-C-96-021 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 81
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6313, Stability to Normal and Elevated Temperatures, Metals, and Metal Ions 1996-08-01 2020-02-28 EPA 712-C-96-022 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 82
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6314, Oxidation/Reduction: Chemical Incompatibility 1996-08-01 2020-02-28 EPA 712-C-96-023 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 83
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6315, Flammability 1996-08-01 2020-02-28 EPA 712-C-96-024 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 84
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6316, Explodability 1996-08-01 2020-02-28 EPA 712-C-96-025 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 85
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6317, Storage Stability 2002-06-01 2020-02-28 EPA 712-C-96-026 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 86
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6319, Miscibility 1996-08-01 2020-02-28 EPA 712-C-96-027 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 87
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6320, Corrosion Characteristics 1996-08-01 2020-02-28 EPA 712-C-96-028 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 88
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.6321, Dielectric Breakdown Voltage 1996-08-01 2020-02-28 EPA 712-C-96-029 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 89
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7000, pH 1996-08-01 2020-02-28 EPA 712-C-96-030 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 90
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7050, UV/Visible Absorption 1996-08-01 2020-02-28 EPA 712-C-96-031 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 91
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7100, Viscosity 1996-08-01 2020-02-28 EPA 712-C-96-032 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 92
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7200, Melting Point/Melting Range 1998-03-01 2020-02-28 EPA 712-C-96-033 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 93
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7220, Boiling Point/Boiling Range 1996-08-01 2020-02-28 EPA 712-C-96-034 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 94
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7300, Density/Relative Density/Bulk Density 2002-06-01 2020-02-28 EPA 712-C-96-035 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 95
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7370, Dissociation Constants in Water 1996-08-01 2020-02-28 EPA 712-C-96-036 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 96
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7520, Particle Size, Fiber Length, and Diameter Distribution 1996-08-01 2020-02-28 EPA 712-C-96-037 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 97
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7550, Partition Coefficient (n-octanol/water), Shake Flask Method 1996-08-01 2020-02-28 EPA 712-C-96-038 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 98
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7560, Partition Coefficient (n-octanol/water), Generator Column Method 1996-08-01 2020-02-28 EPA 712-C-96-039 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 99
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7570, Partition Coefficient (n-octanol/water), Estimation by Liquid Chromatography 1996-08-01 2020-02-28 EPA 712-C-96-040 Test Guideline; Product Properties; Partition Coefficient This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 100
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7840, Water Solubility: Column Elution Method; Shake Flask Method 1998-03-01 2020-02-28 EPA 712-C-96-041 Test Guideline; Product Properties; Water Solubility This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 101
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7860, Water Solubility, Generator Column Method 1998-03-01 2020-02-28 EPA 712-C-96-042 Test Guideline; Product Properties; Water Solubility This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 102
Product Properties Test Guidelines: Physical/Chemical Properties Test Guidelines, 830.7950, Vapor Pressure 1996-08-01 2020-02-28 EPA 712-C-96-043 Test Guideline; Product Properties; Vapor Pressure This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 103
Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1550, Product Identity and Composition 1996-08-01 2020-02-28 EPA 712-C-96-006 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 70
Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1600, Description of Materials Used to Produce the Product 1996-08-01 2020-02-28 EPA 712-C-96-007 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 71
Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1620, Description of Production Process 1996-08-01 2020-02-28 EPA 712-C-96-008 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 72
Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1650, Description of Formulation Process 1996-08-01 2020-02-28 EPA 712-C-96-009 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 73
Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1670, Discussion of Formation of Impurities 1996-08-01 2020-02-28 EPA 712-C-96-010 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 74
Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1700, Preliminary Analysis 1996-08-01 2020-02-28 EPA 712-C-96-011 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 75
Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1750, Certified Limits 1996-08-01 2020-02-28 EPA 712-C-96-012 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 76
Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1800, Enforcement Analytical Method 1996-08-01 2020-02-28 EPA 712-C-96-013 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 77
Product Properties Test Guidelines: Product Identity, Composition, and Analysis Test Guidelines, 830.1900, Submittal of Samples 2008-11-01 2020-02-28 EPA 712-F-08-002 Test Guideline; Product Properties This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPP RD 78
Protecting Pets from Fleas and Ticks 2018-10-17 2020-02-28 EPA 705-G-2020-2988 Pesticide Registration Links to information about controlling fleas, ticks and other related guidance. OPP RD 2988
Protection of Proprietary Data Rights for Data Used to Support Tolerance Exemptions for Inert Ingredients 2017-03-13 2020-02-28 EPA 705-G-2020-1493 Pesticide Registration; Protection Data Rights; Inert Ingredients; Tolerance Exemptions The FFDCA provides both exclusive use and data compensation protections for data that inert ingredient manufacturers submit to EPA to establish or maintain tolerances or tolerance exemptions for these ingredients. Find information about these protections. OPP RD 1493
QA Testing for the AOT425StatPgm Program 2001-06-01 2020-02-28 EPA 705-G-2020-2861 acute oral toxicity; up and down; 870.1100; OECD 425 Guidance for how to use the AOT425StatPgm Program; description of the model, how to use, how to construct data sets and compare. OPP RD 2861
Questions and Answers - Exclusive Use Data Protection for Minor Use Registrations 2018-02-01 2020-02-28 EPA 705-G-2020-2970 Exclusive Use; Minor Use; Pesticide Registration This document contains guidance on Exclusive Use Data Protection for Minor Use Registrations. OPP RD 2970
Questions and Answers - Extension of Exclusive Data and Minor Use Designation, Suggestions to Applicants for Agronomic Information 2016-11-01 2020-02-28 EPA 705-G-2020-2971 Exclusive Use; Minor Use; Pesticide Registration This document contains guidance for extending exclusive data and requesting minor use designation. OPP RD 2971
Registration Requirements and Guidance 2017-04-18 2020-02-28 EPA 705-G-2020-0467 Pesticide Registration; Requirements; Guidance; Forms; Data Requirements This page lists the categories of requirements that all applicants for all categories of pesticides must complete to help you navigate the process. OPP RD 467
Regulation of Pesticide Residues on Food 2019-04-30 2020-02-28 EPA 705-G-2020-2787 Pesticide Registration; tolerances This page provides links to guidance about tolerances. OPP RD 2787
Repellency Awareness Graphic 2016-01-01 2020-02-28 EPA 705-G-2020-2902 Pesticide Registration Overview of the repellency awareness graphic OPP RD 2902
Repellents: Protection against Mosquitoes, Ticks and Other Arthropods 2019-04-30 2020-02-28 EPA 705-G-2020-2987 Pesticide Regulation This page offers information about preventing bites and insect repellents and includes links to related guidance. OPP RD 2987
Response to letter dated July 27, 3018, concerning a situation where an unforeseen foreign production site closure has led to disruption in availability of 1,2-benzisothiazolin-3-one (BIT) (CAS Reg. No. 2634-33-5) 2018-08-23 2020-02-28 EPA 705-G-2020-2500 Pesticide Registration; BIT self-certification This letter contains the Agency's response to a registrant letter regarding a request for self-certification when an unforeseen foreign production site closure has led to a disruption in availability of BIT. OPP RD 2500
Response to letter dated November 8, 2018, requesting that the Agency expand the expedited process for minor formulation amendments (MFAs) described in our October 18, 2018, letter 2018-12-21 2020-02-28 EPA 705-G-2020-2499 Pesticide Registration; MFA This letter contains the Agency's response to a registrant letter regarding expanding the expedited process for minor formulation amendments OPP RD 2499
Sales Reporting Template (XLSX) 2017-03-01 2020-02-28 EPA 705-G-2020-2873 Enhanced reporting, adverse incident, pet spot-on, sales EPA's standardized template for submission of corresponding enhanced reporting sales data OPP RD 2873
Spanish Translation Guide for Pesticide Labeling 2019-10-10 2020-02-28 EPA 705-G-2020-2066 Pesticide Labels Spanish translations of health and safety information for use on pesticide product labels. OPP RD 2066
Spot-on Enhanced Reporting Pilot Concluding Webinar and Implementation (PDF) 2018-05-10 2020-02-28 EPA 705-G-2020-2871 Standardized Templates, Enhanced Reporting, Incident, Sales, Mitigation, Implementation; Conditions of Registration, expiration PDF of Webinar PowerPoint presentation. OPP RD 2871
Spot-On Enhanced Reporting Pilot Template Development Synopsis 2018-01-23 2020-02-28 EPA 705-G-2020-2839 pets, spot-on Products; reporting sales and incident Spot-On Enhanced Reporting Pilot Template Development Synopsis PDF. OPP RD 2839
Standard house mouse acute dry bait laboratory test method 1991-10-08 2020-02-28 EPA 705-G-2020-2482 Pesticide Registration; bait This method is designed to determine the effectiveness of ready-to-use acute dry bait rodenticide products used for house mouse control. OPP RD 2482
Standard house mouse acute liquid bait laboratory test method 1991-09-27 2020-02-28 EPA 705-G-2020-2484 Pesticide Registration; bait This method is designed to determine the effectiveness of acute rodenticide products used to make liquid baits for controlling house mice. OPP RD 2484
Standard house mouse acute technical and concentrated dry bait laboratory test method 1992-12-14 2020-02-28 EPA 705-G-2020-2492 Pesticide Registration; bait This method is designed to determine the effectiveness of dry bait technical and concentrated acute rodenticide products for house mice. OPP RD 2492
Standard house mouse acute tracking powder efficacy laboratory test method 1992-12-15 2020-02-28 EPA 705-G-2020-2491 Pesticide Registration; powder This method is designed to determine the effectiveness of acute tracking powder for house mice. OPP RD 2491
Standard house mouse anticoagulant dry bait laboratory test method 1991-06-18 2020-02-28 EPA 705-G-2020-2487 Pesticide Registration; bait This method is designed to determine the effectiveness of dry bait anticoagulant rodenticide products used for control of house mice. OPP RD 2487
Standard house mouse anticoagulant liquid bait laboratory test method 1991-06-17 2020-02-28 EPA 705-G-2020-2489 Pesticide Registration; bait This method is designed to determine the effectiveness of anticoagulant rodenticide products used to make liquid baits for controlling house mice. OPP RD 2489
Standard house mouse anticoagulant placepack penetration laboratory test method 1975-01-01 2020-02-28 EPA 705-G-2020-2474 Pesticide Registration; bait This method is designed to determine the effectiveness of anticoagulant dry bait rodenticide products used in placepacks for house mouse control. OPP RD 2474
Standard house mouse anticoagulant technical and concentrated dry bait laboratory test method 1992-12-13 2020-02-28 EPA 705-G-2020-2493 Pesticide Registration; bait This method is designed to determine the effectiveness of dry bait anticoagulant technical and concentrated rodenticide products for standard house mice. OPP RD 2493
Standard house mouse anticoagulant tracking powder efficacy laboratory test method 1991-09-27 2020-02-28 EPA 705-G-2020-2480 Pesticide Registration; powder This method is designed to determine the effectiveness of anticoagulant tracking powder rodenticide products for house mice. OPP RD 2480
Standard house mouse anticoagulant wax block and wax pellet laboratory test method 1975-01-01 2020-02-28 EPA 705-G-2020-2478 Pesticide Registration; wax block and pellet This method is designed to determine the effectiveness anticoagulant rodenticide products claimed to be suitable to use for house mouse control in wet or damp environments. OPP RD 2478
Standard mouse acute placepack dry bait laboratory test method 1976-09-01 2020-02-28 EPA 705-G-2020-2472 Pesticide Registration; bait This method is designed to determine the effectiveness of acute dry bait rodenticide products used in placepacks for control of house mice. OPP RD 2472
Standard norway rat and roof rat acute placepack dry bait laboratory test method 1976-09-01 2020-02-28 EPA 705-G-2020-2473 Pesticide Registration; bait This method is designed to determine the effectiveness of acute dry bait rodenticide products used in placepacks for control of Norway and roof rats. OPP RD 2473
Standard norway rat and roof rat anticoagulant liquid bait laboratory test method 1991-06-16 2020-02-28 EPA 705-G-2020-2490 Pesticide Registration; bait This method is designed to determine the effectiveness of anticoagulant rodenticide products used to make liquid baits for controlling commensal rats. OPP RD 2490
Standard norway rat and roof rat anticoagulant placepack dry bait laboratory test method 1975-01-01 2020-02-28 EPA 705-G-2020-2475 Pesticide Registration; bait This method is designed to determine the effectiveness of anticoagulant dry bait rodenticide products used in placepacks for rat control. OPP RD 2475
Standard norway rat anticoagulant wax block and wax pellet laboratory test method 1990-12-02 2020-02-28 EPA 705-G-2020-2479 Pesticide Registration; wax block and pellet This method is designed to determine the effectiveness anticoagulant rodenticide products claimed to be suitable to use for rat control in wet or damp environments. OPP RD 2479
Standard norway rat/roof rat acute dry bait laboratory test method 1991-10-08 2020-02-28 EPA 705-G-2020-2483 Pesticide Registration; bait This method is designed to determine the effectiveness of ready-to-use acute dry bait rodenticide products used for rat control. OPP RD 2483
Standard norway rat/roof rat acute liquid bait laboratory test method 1991-06-19 2020-02-28 EPA 705-G-2020-2485 Pesticide Registration; bait This method is designed to determine the effectiveness of products used in acute liquid bait rodenticides used to control Norway and roof rats OPP RD 2485
Standard norway rat/roof rat acute technical and concentrated dry bait laboratory test method 1992-12-13 2020-02-28 EPA 705-G-2020-2496 Pesticide Registration; bait This method is designed to determine the effectiveness of dry bait technical and concentrated acute rodenticide products for standard Norway and roof rats. OPP RD 2496
Standard norway rat/roof rat acute tracking powder efficacy laboratory test method 1992-12-17 2020-02-28 EPA 705-G-2020-2481 Pesticide Registration; powder This method is designed to determine the effectiveness of acute tracking powder used for control of Norway or roof rats. OPP RD 2481
Standard norway rat/roof rat anticoagulant dry bait laboratory test method 1991-06-18 2020-02-28 EPA 705-G-2020-2488 Pesticide Registration; bait This method is designed to determine the effectiveness of ready-to-use dry bait anticoagulant rodenticide products used for control of rats. OPP RD 2488
Standard norway rat/roof rat anticoagulant technical and concentrated dry bait laboratory test method 1976-05-06 2020-02-28 EPA 705-G-2020-2471 Pesticide Registration; bait This method is designed to determine the effectiveness of dry bait anticoagulant technical and concentrated rodenticide products for standard Norway and roof rats. OPP RD 2471
Standard norway rat/roof rat anticoagulant tracking powder efficacy laboratory test method 1991-06-19 2020-02-28 EPA 705-G-2020-2486 Pesticide Registration; powder This method is designed to determine the effectiveness of anticoagulant tracking powder rodenticide products for rats. OPP RD 2486
Standard peromyscus species acute dry bait laboratory test method 1975-01-01 2020-02-28 EPA 705-G-2020-2477 Pesticide Registration; bait This method is designed to determine the effectiveness of acute dry bait rodenticide products used for control of Peromyscus spp. OPP RD 2477
Standard peromyscus species acute technical and concentrated dry bait laboratory test method 1992-12-15 2020-02-28 EPA 705-G-2020-2494 Pesticide Registration; bait This method is designed to determine the effectiveness of ready-to-use dry bait technical and concentrated acute rodenticide products for Peromyscus spp. OPP RD 2494
Standard peromyscus species anticoagulant dry bait laboratory test method 1975-01-01 2020-02-28 EPA 705-G-2020-2476 Pesticide Registration; bait This method is designed to determine the effectiveness of ready-to-use dry bait anticoagulant rodenticide products used for control of Peromyscus spp. OPP RD 2476
Standard peromyscus species anticoagulant technical and concentrated dry bait laboratory test method 1992-12-15 2020-02-28 EPA 705-G-2020-2495 Pesticide Registration; bait This method is designed to determine the effectiveness of ready-to-use dry bait anticoagulant technical and concentrated rodenticide products used for control of Peromyscus spp. OPP RD 2495
State FIFRA Issues, Research, and Evaluation Group Final Guidance for State Lead Agencies for the Development and Implementation of Managed Pollinator Protection Plans 2015-04-03 2020-02-28 EPA 705-G-2020-2504 Pollinator Protection This document contains guidance for states on the development and implementation of managed pollinator protection plans. OPP RD 2504
Strategic Vision for Adopting 21st Century Science Methodologies 2018-04-10 2020-02-28 EPA 705-G-2020-2801 Pesticide Registration; Risk Assessment; integrated approaches to testing and assessment (IATA) This guidance relates to the use of new technologies in molecular, cellular, computational sciences to supplement or replace traditional methods of toxicity testing and risk assessment. OPP RD 2801
Study Profile Templates 2017-04-25 2020-02-28 EPA 705-G-2020-0432 Pesticide Registration; Study Profile Templates Listing of study profile templates and brief description about each to include downloadable file in Word and/or PDF formats. OPP RD 432
Suggested Format for Acute Toxicity Studies 2008-06-01 2020-02-28 EPA 705-G-2020-0503 Pesticide Registration; Format Acute Toxicity Studies This document suggests the format for final reports on pesticide studies (right column of the tables in the document) and provides instructions for the creation of PDF Version 1.3 electronic submission documents (left column of the tables). OPP RD 503
Suggestions for Applicants on Information Considered when Evaluating Benefits of New Conventional Active Ingredients/Significant New Use Site Requests 2018-09-01 2020-02-28 EPA 705-G-2020-2432 benefits; new active ingredient In order to assist registrants of conventional pesticides, through this webpage, EPA is providing some suggestions on the types of information applicants could provide that would help BEAD review the benefits that accrue to potential users of the pesticide as part of the registration process.  OPP RD 2432
Test Guidelines for Pesticide Data Requirements 2017-05-23 2020-02-28 EPA 705-G-2020-1395 Pesticide Science and Assessing Pesticide Risks In evaluating a pesticide registration application, EPA assesses a wide variety of potential human health and environmental effects associated with use of the product. OPP RD 1395
Toxicology Guidance: Performance of the Up-and-Down Procedure 2017-03-29 2020-02-28 EPA 705-G-2020-2862 acute oral toxicity; up and down; 870.1100; OECD 425 This summary is intended to accompany the Up-and-Down Procedure (UDP) test guideline and the AOT425StatPgm program and assist the user in interpreting its output. The UDP guideline uses the maximum likelihood estimation method for calculation of the LD50 and profile likelihood (PL) methods for estimation of most confidence intervals. This summary addresses choice of dose progression and initial dose level for the UDP and describes the performance of the test under a variety of circumstances. OPP RD 2862
Trade Name Database 2020-02-14 2020-02-28 EPA 705-G-2020-2934 Pesticide registration, inerts The List of Trade Names of Inert Ingredients database is intended solely to enhance public access to information related to the EPA approval status of trade name inert ingredients used in pesticide products. OPP RD 2934
U.S. Environmental Protection Agency's Policy to Mitigate the Acute Risk to Bees from Pesticide Products 2017-01-12 2020-02-28 EPA 705-G-2020-2770 Pollinator Protections; bees Policy document describing the EPA's approach to mitigate acute risk from pesticides to bees. OPP RD 2770
Understanding the Science behind EPA’s Pesticide Decisions 2019-08-02 2020-02-28 EPA 705-G-2020-2898 Pesticide Registration Understanding the Science behind EPA’s Pesticide Decisions OPP RD 2898
Use of the Local Lymph Node Assay and Reduced Dose Protocol for LLNA in Assessing Pesticide Products 2019-08-08 2020-02-28 EPA 705-G-2020-2458 Pesticide Registration; LLNA; Reduced protocol This policy is intended to expand the usefulness the traditional (or radiolabeled) LLNA protocol for assessment of dermal sensitization potential to single component pesticide products (i.e., technical grade active ingredients) and to pesticides with multiple components (i.e., end use products). OPP RD 2458
User Documentation for the AOT425StatPgm Program 2003-06-01 2020-02-28 EPA 705-G-2020-2859 acute oral toxicity; up and down; 870.1100; OECD 425 Guidance for how to use the AOT425StatPgm Program. OPP RD 2859
Voluntary Cancellation of a Pesticide Product or Use 2019-12-03 2020-02-28 EPA 705-G-2020-2463 Pesticide Registration; voluntary cancellation This site provides guidance on voluntarily cancelling a pesticide use or registration. OPP RD 2463
2006 IUR Resources 2013-03-21 2020-02-28 EPA 705-G-2020-0456 Chemical Data Reporting Submission resources for the 2006 IUR Reporting Period. OPPT CCD 456
2016 Chemical Data Reporting Frequent Questions 2016-07-18 2020-02-28 EPA 705-G-2020-1568 Chemical Data Reporting These Frequent Questions (FQs) are intended to clarify the reporting requirements for Chemical Data Reporting for the 2016 reporting period. They have been updated and reposted on the website for each reporting period beginning in 1986. OPPT CCD 1568
2016 Chemical Data Reporting Training Modules 2016-05-04 2020-02-28 EPA 705-G-2020-1554 Chemical Data Reporting The following seven training modules were developed to assist those who may be required to submit reports in 2012 in response to the Chemical Data Reporting (CDR) under TSCA. OPPT CCD 1554
Background and Discussion Questions for Identifying Priority Chemicals for Review and Assessment 2016-02-12 2020-02-28 EPA 705-G-2020-1503 Assessing and Managing Chemicals under TSCA This discussion guide is intended to be used to help structure public input during the September 2011 webinar and discussion forum addressing the prioritization factors and data sources EPA plans to use to identify priority chemicals for review. OPPT CCD 1503
Basic Information on TSCA Import-Export Requirements 2015-01-27 2020-02-28 EPA 705-G-2020-1250 TSCA Import-Export Requirements Describes various TSCA import and export requirements under various Sections of TSCA and the CFR. OPPT CCD 1250
Case Studies 2016-07-06 2020-02-28 EPA 705-G-2020-2267 Chemical Data Reporting This document presents case studies to help you in reporting for 2016 Chemical Data Reporting (CDR). EPA designed these examples to illustrate reporting requirements published as part of the CDR Rule (published August 16, 2011), and to address general reporting issues from the 2012 CDR. OPPT CCD 2267
CDR Registration in CDX 2012-02-08 2020-02-28 EPA 705-G-2020-0458 Chemical Data Reporting This document is an overview presentation of the CDX Registration Process. OPPT CCD 458
Chemical Data Reporting - Previously Collected Data 2013-04-30 2020-02-28 EPA 705-G-2020-0471 Chemical Data Reporting EPA now refers to the Inventory Update Reporting (IUR) rule as the Chemical Data Reporting (CDR) Rule. This change was effective with the publication of the Inventory Update Reporting Modifications; Chemical Data Reporting Final Rule in August 2011. OPPT CCD 471
Chemical Data Reporting Byproduct and Recycling Scenarios 2013-04-03 2020-02-28 EPA 705-G-2020-0461 Chemical Data Reporting This document addresses a series of 18 industry scenarios and questions related to EPA’s Chemical Data Reporting (CDR) rule. The primary goal of this document is to help the regulated community comply with the requirements of the CDR rule. OPPT CCD 461
Chemical Data Reporting Instructions Regarding Confidentiality 2013-03-20 2020-02-28 EPA 705-G-2020-0452 Chemical Data Reporting Provides instructions on how to claim and submit company confidential information for IUR to EPA. OPPT CCD 452
Chemical Substances which are the Subject of Certain TSCA Actions 2015-03-30 2020-02-28 EPA 705-G-2020-2270 Chemical Data Reporting This fact sheet provides information for people who may be subject to the Chemical Data Reporting (CDR) rule on how their requirements for reporting for 2016 may be affected when chemical substances are the subject of certain actions under the Toxic Substances Control Act (TSCA). For 2016, manufacturers must consider the effect of certain TSCA actions on reporting thresholds when determining whether they need to report. And as in 2012, manufacturers of chemicals subject to certain TSCA actions may not be eligible for some of the exemptions which reduce or eliminate reporting requirements. OPPT CCD 2270
ChemView User Interface Guide 2013-09-05 2020-02-28 EPA 705-G-2020-1372 Assessing and Managing Chemicals under TSCA A guide for users of the ChemView database system. OPPT CCD 1372
e-CDRweb User Guide – Secondary Authorized Official 2012-03-19 2020-02-28 EPA 705-G-2020-0475 Chemical Data Reporting This document presents the user guide for the Office of Pollution Prevention and Toxics’ (OPPT) e-CDRweb tool. E-CDRweb is the electronic, web-based tool provided by the Environmental Protection Agency (EPA) for the submission of Chemical Data Reporting (CDR) information. This document is the user guide for the Secondary Authorized Official (AO) user of the e-CDR web tool. OPPT CCD 475
eCDRweb User Guide–Primary Authorized Official 2012-03-19 2020-02-28 EPA 705-G-2020-0473 Chemical Data Reporting This document presents the user guide for the Office of Pollution Prevention and Toxics’ (OPPT) e-CDRweb tool. E-CDRweb is the electronic, web-based tool provided by the Environmental Protection Agency (EPA) for the submission of Chemical Data Reporting (CDR) information. This document is the user guide for the Primary Authorized Official (AO) user of the e-CDR web tool OPPT CCD 473
eCDRweb User Guide–Primary Support 2012-03-19 2020-02-28 EPA 705-G-2020-0474 Chemical Data Reporting This document presents the user guide for the Office of Pollution Prevention and Toxics’ (OPPT) e-CDR web tool. E-CDRweb is the electronic, web-based tool provided by the Environmental Protection Agency (EPA) for the submission of Chemical Data Reporting (CDR) information. This document is the user guide for the Primary Support user of the e-CDRweb tool. OPPT CCD 474
eCDRweb User Guide–Secondary Support 2012-03-19 2020-02-28 EPA 705-G-2020-0476 Chemical Data Reporting This document presents the user guide for the Office of Pollution Prevention and Toxics’ (OPPT) e-CDR web tool. E-CDRweb is the electronic, web-based tool provided by the Environmental Protection Agency (EPA) for the submission of Chemical Data Reporting (CDR) information. This document is the user guide for the Secondary Support user of the e-CDRweb tool. OPPT CCD 476
eCDRweb: XML Upload Session 2012-04-17 2020-02-28 EPA 705-G-2020-0462 Chemical Data Reporting IUR, TSCA, Inventory Update Reporting, 2006, Basic information, History, General, Inventory Update Reporting and Chemical Data Reporting OPPT CCD 462
Electronic Reporting Requirements for Certain Information under the Toxic Substances Control Act 2013-12-04 2020-02-28 EPA 705-G-2020-0587 Assessing and Managing Chemicals under TSCA Describes TSCA eReporting guidance and information. OPPT CCD 587
EPA Response 1 to Bergeson & Campbell Letter from Lynn L. Bergeson and the Metals Chemistry Forum regarding IUR/CDR Requirements for Byproducts and Applicable Exemptions 2005-10-27 2020-02-28 EPA 705-G-2020-3144 Inventory Update Rule/Chemical Data Reporting EPA Response 1 to Bergeson & Campbell Letter from Lynn L. Bergeson and the Metals Chemistry Forum regarding Inventory Update Rule (IUR)/Chemical Data Reporting (CDR) Requirements for Byproducts and Applicable Exemptions OPPT CCD 3144
EPA Response 2 to Bergeson & Campbell Letter from Lynn L. Bergeson and the Metals Chemistry Forum regarding IUR/CDR Requirements for Mixtures and Component Chemicals 2006-01-19 2020-02-28 EPA 705-G-2020-3145 Inventory Update Rule/Chemical Data Reporting EPA Response 2 to Bergeson & Campbell Letter from Lynn L. Bergeson and the Metals Chemistry Forum regarding Inventory Update Rule (IUR)/Chemical Data Reporting (CDR) Requirements for Mixtures and Component Chemicals OPPT CCD 3145
EPA Response Summary - A General Summary of Inventory Update Rule (IUR)/Chemical Data Reporting (CDR)-related Issues for Utilities 2006-10-19 2020-02-28 EPA 705-G-2020-3146 Inventory Update Rule/Chemical Data Reporting A summary of the information most frequently requested by utilities. The following may or may not apply to each specific utility. This information is very general, and each utility needs to consider its own systems. This information is in no way comprehensive, but should provide enough information to help each reporter evaluate their own systems. OPPT CCD 3146
EPA Response to American Forest & Paper Association (AF&PA) Letter from Dr. John L. Festa regarding IUR/CDR Requirements for Pulp and Paper/Kraft Pulping Cycle Chemicals 2006-11-01 2020-02-28 EPA 705-G-2020-3147 Inventory Update Rule/Chemical Data Reporting EPA Response to American Forest & Paper Association (AF&PA) Letter from Dr. John L. Festa regarding Inventory Update Rule (IUR)/Chemical Data Reporting (CDR) Requirements for Pulp and Paper/Kraft Pulping Cycle Chemicals (Liquors - Black, White, and Green; Calcium Carbonate; and Calcium Oxide) OPPT CCD 3147
EPA Response to Williams & Vanino letter from Marcia E. Williams regarding TSCA Definitions Applied to Recycling and IUR/CDR Requirements for Wastes and Byproducts 1993-12-02 2020-02-28 EPA 705-G-2020-3142 Inventory Update Rule/Chemical Data Reporting EPA Response to Williams & Vanino letter from Marcia E. Williams regarding TSCA Definitions Applied to Recycling and Inventory Update Rule (IUR)/Chemical Data Reporting (CDR) Requirements for Wastes and Byproducts OPPT CCD 3142
EPA Response/Answers to Questions Submitted by GE regarding TSCA IUR/CDR Requirements 2004-11-08 2020-02-28 EPA 705-G-2020-3143 Inventory Update Rule/Chemical Data Reporting EPA Response/Answers to Questions Submitted by General Electric (GE) regarding TSCA Inventory Update Reporting (IUR)/Chemical Data Reporting (CDR) Requirements OPPT CCD 3143
Example Primary and Secondary Form U 2016-03-30 2020-02-28 EPA 705-G-2020-2266 Forms displaying all reportable CDR data elements Following is an example of the primary and secondary Form U used to make 2016 Chemical Data Reporting (CDR) submissions. The secondary Form U is used for joint submissions. This form must be submitted electronically via the Central Data Exchange. OPPT CCD 2266
Examples and Case Studies for the 2012 Chemical Data Reporting 2013-04-09 2020-02-28 EPA 705-G-2020-0464 Chemical Data Reporting This document presents examples and case studies to help you in reporting for 2012 Chemical Data Reporting (CDR), formerly known as Inventory Update Reporting (IUR). EPA designed these examples to illustrate the new reporting requirements, which were published as part of the CDR Rule (published August 16, 2011), and to address general reporting issues from the 2006 IUR. OPPT CCD 464
Exposure-based Policy Letter to Chemical Manufacturers Association 1988 1988-09-01  2020-02-28 EPA 705-G-2020-1394 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) The following 1988 letter from EPA to the Chemical Manufacturers Association explains EPA’s exposure-based policy in the New Chemicals Program. OPPT CCD 1394
Exposure-Based Policy under Section 5 of TSCA 2012-06-27 2020-02-28 EPA 705-G-2020-1240 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) TSCA section 5(e) provides EPA with the authority to regulate new substances based on potential risks or the potential for significant human exposure or substantial environmental release ("exposure-based"). This page describes the latter policy. OPPT CCD 1240
Fact Sheet:  Reporting Manufactured Chemical Substances from Metal Mining & Related Activities 2016-05-09 2020-02-28 EPA 705-G-2020-2276 Industry-Specific Fact Sheet This fact sheet provides guidance on the Chemical Data Reporting (CDR) rule requirements related to the reporting of mined metals, intermediates, and byproducts manufactured during metal mining and related activities. OPPT CCD 2276
Fact Sheet:  Toll Manufacturing 2016-02-22 2020-02-28 EPA 705-G-2020-2273 Industry-Specific Fact Sheet This fact sheet provides information on existing Chemical Data Reporting (CDR) regulations to persons who are involved in toll manufacturing of chemical substances which may be subject to the CDR rule. OPPT CCD 2273
Fact Sheet: Byproducts Reporting for the Printed Circuit Board Industry 2016-02-23 2020-02-28 EPA 705-G-2020-2277 Industry-Specific Fact Sheet This fact sheet provides information on existing Chemical Data Reporting (CDR) rule requirements related to byproducts reporting by persons who manufacture printed circuit boards and may be subject to CDR. OPPT CCD 2277
Fact Sheet: Changes to Company Ownership or Legal Identity 2015-05-22 2020-02-28 EPA 705-G-2020-2275 Chemical Data Reporting This fact sheet provides information for persons who may be subject to the Chemical Data Reporting (CDR) rule about issues related to changes to company ownership or legal identity which may affect reporting for the 2016 reporting period. OPPT CCD 2275
Fact Sheet: Electricity Generating Sites 2016-04-28 2020-02-28 EPA 705-G-2020-2278 Industry-Specific Fact Sheet This fact sheet provides information on existing Chemical Data Reporting (CDR) rule requirements related to the reporting of chemical substances manufactured during operations conducted at electricity generating sites, such as utilities. OPPT CCD 2278
Fact Sheet: Imported Articles  2015-12-16 2020-02-28 EPA 705-G-2020-2272 Industry-Specific Fact Sheet This fact sheet provides information and sample reporting scenarios on the reporting exemption for the import of a chemical substance as part of an article, for purposes of the Chemical Data Reporting (CDR) rule. OPPT CCD 2272
Fact Sheet: Importers 2015-12-15 2020-02-28 EPA 705-G-2020-2271 Industry-Specific Fact Sheet This fact sheet provides information and sample reporting scenarios on existing Chemical Data Reporting (CDR) regulations to persons who could be considered “importers” for purposes of the CDR rule. OPPT CCD 2271
Fact Sheet: Non-isolated Intermediates 2016-04-26 2020-02-28 EPA 705-G-2020-2274 Industry-Specific Fact Sheet This fact sheet provides information on the reporting exemption applicable to non-isolated intermediate chemical substances for purposes of the Chemical Data Reporting (CDR) rule (40 CFR 711). OPPT CCD 2274
Filing a Pre-manufacture Notice with EPA 2015-09-30 2020-02-28 EPA 705-G-2020-0593 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) A pre-manufacture notice, or PMN, must be submitted to EPA at least 90 days prior to the manufacture or import of the new chemical. Here you can learn about the information needed to submit a PMN, and what to expect after you submit. OPPT CCD 593
Filing a Significant New Use Notice (SNUN) under TSCA 2015-09-30 2020-02-28 EPA 705-G-2020-1239 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) Under section 5(a) of TSCA, if EPA promulgates a Significant New Use Rule, a manufacturer or processor wishing to engage in a designated significant new use must submit a Significant New Use Notice to EPA at least 90 days before engaging in the new use. OPPT CCD 1239
For Your Information (FYI) User Guide – Primary Support 2013-10-28 2020-02-28 EPA 705-G-2020-1441 Assessing and Managing Chemicals under TSCA This document is the user guide for the Primary Support user of the FYI tool which is part of the Office of Pollution Prevention and Toxics (OPPT) ‘For Your Information (FYI)’ application submission process. OPPT CCD 1441
For Your Information (FYI) User Guide–Primary Authorized Official 2013-10-28 2020-02-28 EPA 705-G-2020-1440 Assessing and Managing Chemicals under TSCA This document is the user guide for the Primary Authorized Official (AO) user of the FYI tool which is part of the Office of Pollution Prevention and Toxics (OPPT) ‘For Your Information (FYI)’ application submission process. OPPT CCD 1440
Frequent Questions (FQs) 2016-02-23 2020-02-28 EPA 705-G-2020-2280 CDR Frequently Asked Questions These Frequent Questions (FQs) are intended to clarify the reporting requirements for Chemical Data Reporting for the 2016 reporting period. OPPT CCD 2280
Guidance Documents on Substantial Risk Notifications under TSCA 2015-09-14 2020-02-28 EPA 705-G-2020-1444 Assessing and Managing Chemicals under TSCA Guidance documents for TSCA Section 8(e) which states 'Any person who manufactures a chemical substance and obtains information that the chemical is harmful to health or the environment shall inform the EPA.' OPPT CCD 1444
Guidance for Avoiding Incomplete Premanufacture Notices or Bona Fides in the New Chemicals Program 2014-07-14 2020-02-28 EPA 705-G-2020-0891 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) This page contains documents to help you avoid having an incomplete Premanufacture notice or Bona Fide . The documents go over the chemical identity requirements and common errors that result in incompletes. OPPT CCD 891
Guidance on Regulations Issued Under the Toxic Substances Control Act (TSCA) 2015-08-06 2020-02-28 EPA 705-G-2020-1376 Assessing and Managing Chemicals under TSCA This page provides guidance to assist the regulated community in complying with policies or regulations that EPA has issued under the Toxic Substances Control Act (TSCA). OPPT CCD 1376
Help with Chemical Data Reporting: How to Search for Chemicals Subject to Certain TSCA Actions 2016-03-11 2020-02-28 EPA 705-G-2020-1505 Chemical Data Reporting This document contains instructions on how to identify chemicals that are the subject of certain actions under the Toxic Substances Control Act (TSCA) using the Substance Registry Services (SRS). OPPT CCD 1505
High Molecular Weight Polymers in the New Chemicals Program 2015-03-30 2020-02-28 EPA 705-G-2020-1255 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) There are three categories or types of High Molecular Weight (HMW, 10,000 daltons) polymers typically reviewed by the New Chemicals Program: Soluble, insoluble, and water absorbing. Each of the three types are treated differently. OPPT CCD 1255
How To Report Under Chemical Data Reporting 2013-03-20 2020-02-28 EPA 705-G-2020-0453 Chemical Data Reporting This page contains instructions and guidance on submitting information to EPA for the 2016 Chemical Data Reporting (CDR) period. Provides links to CDR documents and tools that can be used for CDR reporting. OPPT CCD 453
Instruction Manual for Reporting Under the Toxic Substances Control Act §5 New Chemicals Program 2015-05-26 2020-02-28 EPA 705-G-2020-1290 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) This instruction manual will help manufacturers of new chemical substances determine if they need to file a PMN, if their substances are excluded, the requirements and how to submit a notice. OPPT CCD 1290
Instructions for Reporting 2016 2016-03-30 2020-02-28 EPA 705-G-2020-2265 Instructions for Reporting to CDR in 2016 This document, which pertains to EPA CDR reporting during 2016, updates guidance issued for reporting in 2012 to incorporate instructions relevant to 2016 reporting. It provides detailed information and examples to assist manufacturers (including importers) in reporting under the CDR rule. OPPT CCD 2265
Instructions for the 2012 TSCA Chemical Data Reporting 2013-04-04 2020-02-28 EPA 705-G-2020-0463 Chemical Data Reporting This document, which pertains to EPA CDR reporting during 2012, updates guidance issued for reporting in 2006 to incorporate instructions relevant to 2012 reporting. It provides detailed information and examples to in reporting under the CDR rule. OPPT CCD 463
Legislative and Regulatory Authority for Chemical Data Reporting 2015-05-05 2020-02-28 EPA 705-G-2020-1099 Chemical Data Reporting This page discusses CDR legislative authority that supports Chemical Data Reporting OPPT CCD 1099
Low Volume Exemption for New Chemical Review under TSCA 2015-09-30 2020-02-28 EPA 705-G-2020-1413 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) Certain categories of new low-volume chemical substances are exempt from full premanufacture notice (PMN) review, i.e., chemicals manufactured at 10,000 kg/year or less. LVE substances undergo a 30-day review and are not subject to a user fee. OPPT CCD 1413
New Chemical Information Bulletin: Exemptions for Research and Development and Test Marketing 1986-11-01 2020-02-28 EPA 705-G-2020-1391 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) EPA has received numerous questions about the scope of the exemption for R&D, under TSCA section 5(h)(3). This New Chemical Information Bulletin provides more specific guidance to manufacturers and processors of new chemical substances. OPPT CCD 1391
New Chemicals Exposure Limits section 5(e) Order Boilerplate insert under the Toxic Substances Control Act (TSCA) New Chemicals Program 2016-09-12 2020-02-28 EPA 705-G-2020-1285 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) The New Chemicals Exposure Limits (NCELs) section 5(e) Consent Order insert presents the standard NCELs provisions. The actual NCEL concentration is an empty blank to be completed depending on the toxicity of the specific chemical involved. OPPT CCD 1285
Overview of TSCA Chemical Data Reporting Requirements and e?Reporting 2013-03-29 2020-02-28 EPA 705-G-2020-0459 Chemical Data Reporting The presentation included an overview of the 2012 reporting requirements, a discussion of joint reporting, a discussion of considerations related to the reporting of by-products and updated information about registering for electronic reporting and for using the electronic reporting tool. OPPT CCD 459
Points to Consider in the Preparation of TSCA Biotechnology Submissions for Microorganisms 1997-06-02 2020-02-28 EPA 705-G-2020-3095 Biotechnology; microorganisms;  Points to Consider when submitting biotechnology submissions for microorganisms to the new chemicals program OPPT CCD 3095
Policy Statement on a New Chemicals Category for Persistent, Bioaccumulative, and Toxic (PBT) Chemicals 1998-10-05 2020-02-28 EPA 705-G-2020-1256 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) On November 4, 1999, EPA issued its policy statement on a category for Persistent Bioaccumulative and Toxic (PBT) new chemicals. The statement provides guidance criteria for persistence, bioaccumulation, and toxicity for new chemicals. OPPT CCD 1256
Policy Statement on a New Chemicals Category for Persistent, Bioaccumulative, and Toxic (PBT) Chemicals 1999-11-04 2020-02-28 EPA 705-G-2020-3117 Persistent Bioaccumulative and Toxic (PBT) new chemicals PBT policy OPPT CCD 3117
Polymer Exemption for New Chemicals under the Toxic Substances Control Act (TSCA) 1995-03-29/td> 2020-02-28 EPA 705-G-2020-1415 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) EPA has established an exemption for certain polymers to encourage manufacturers to make safer polymers. To learn more about this exemption, eligibility, and it's requirements, read this overview of the exemption. OPPT CCD 1415
Polymer Exemption Guidance Manual for premanufacture notices for new chemicals under the Toxic Substances Control Act (TSCA) 1997-06-01 2020-02-28 EPA 705-G-2020-1254 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) A technical manual to accompany, but not supersede the "Premanufacture Notification Exemptions; Revisions of Exemptions for Polymers; Final Rule" found at 40 CFR Part 723, (60) FR 16316-16336, published Wednesday, March 29, 1995. OPPT CCD 1254
Qs & As for the New Chemicals Program 2004-01-01 2020-02-28 EPA 705-G-2020-3096 New Chemicals; questions and answers This Questions & Answers document for the New Chemicals Program is intended only to explain the requirements of TSCA section 5 and selected EPA regulations implementing section 5, and to provide useful information to persons subject to these requirements. OPPT CCD 3096
Questions and Answers About IUR Reporting 2013-05-06 2020-02-28 EPA 705-G-2020-0486 Chemical Data Reporting This document addresses specific questions related to reporting for the 2006 IUR. OPPT CCD 486
Questions and Answers for Reporting for the 2006 Partial Updating of the TSCA Chemical Inventory Database: Inorganic Chemicals Addendum 2013-05-06 2020-02-28 EPA 705-G-2020-0488 Chemical Data Reporting This document addresses specific questions related to reporting inorganic chemicals under the IUR and is an addendum to the Questions and Answers for Reporting for the 2006 Partial Updating of the TSCA Chemical Inventory Database (Questions and Answers Document). OPPT CCD 488
Questions for EPA Interpretive Guidance 2015-05-01 2020-02-28 EPA 705-G-2020-1446 Describes final policy statement of policy, and criteria for evaluation substantial production, substantial release or significant human exposure for the TSCA Section 4 authority This document provides guidance to assist the regulated community in complying with policies or regulations that EPA has issued under the Toxic Substances Control Act (TSCA). OPPT CCD 1446
Registration and Agreement for TSCA Section 8(e) Compliance Audit Program 2016-01-07 2020-02-28 EPA 705-G-2020-1497 Assessing and Managing Chemicals under TSCA This Federal register notification contains the text of an Registration and Agreement for TSCA Section 8(e) Compliance Audit Program ("CAP Agreement"). The pdf contains information on the TSCA Section 8(e) Compliance Audit Program, the registration provisions and CAP Agreement conditions as described. OPPT CCD 1497
Replacement of 5-digit NAICS Codes with Industrial Sector Codes 2013-04-09 2020-02-28 EPA 705-G-2020-0465 Chemical Data Reporting For the 2006 IUR, respondents provided the five-digit North American Industry Classification System (NAICS) Code to describe the setting in which industrial processing and use occurred. OPPT CCD 465
Reporting a TSCA Chemical Substantial Risk Notice 2015-09-14 2020-02-28 EPA 705-G-2020-1439 Assessing and Managing Chemicals under TSCA TSCA 8(e) webpage: Reporting a TSCA Chemical Substantial Risk Notice - Section 8(e) states that Any person who manufactures a chemical substance and obtains information that the chemical is harmful to health or the environment shall inform the EPA. OPPT CCD 1439
Reporting Byproducts for Chemical Data Reporting (CDR) 2013-04-03 2020-02-28 EPA 705-G-2020-0460 Chemical Data Reporting Information on how to report byproducts for the 2012 Chemical Data Reporting Rule. OPPT CCD 460
Reporting Thresholds for 2016 2015-03-30 2020-02-28 EPA 705-G-2020-2269 Chemical Data Reporting This fact sheet provides information for persons who may be subject to the Chemical Data Reporting (CDR) rule about regulatory reporting thresholds that are applicable to the 2016 reporting period. For 2016, manufacturers must consider production volume from 2012 – 2015 as well as the effect of certain actions under the Toxic Substances Control Act (TSCA) on certain reporting thresholds when determining whether they need to report. OPPT CCD 2269
Sample EPA Biotech Form 2009-06-01 2020-02-28 EPA 705-G-2020-1485 Regulation of Biotechnology under TSCA and FIFRA This sample “EPA Biotech Form” is a header sheet that will accompany all biotechnology submission choices, including MCANs, TERAs, Tier I and Tier II exemption, and biotechnology Test Market Exemption Applications (TMEAs). OPPT CCD 1485
Section 8(a) PAIR and FYI Reporting Webinar 2012-09-18 2020-02-28 EPA 705-G-2020-1442 Assessing and Managing Chemicals under TSCA A webinar presentation demonstrating the TSCA Section 8(a) and FYI Reporting tool for electronic notice submissions. OPPT CCD 1442
Section 8(d) Health & Safety Data Reporting and Section 8(e) Notice Webinar 2015-09-14 2020-02-28 EPA 705-G-2020-1443 Assessing and Managing Chemicals under TSCA A webinar presentation demonstrating the TSCA Section 8(d) Health & Safety Data Reporting and Section 8(e) Notice Reporting tool for electronic submissions. OPPT CCD 1443
Section 8(e) Notice User Guide – Primary Authorized Official 2013-10-28 2020-02-28 EPA 705-G-2020-1437 Assessing and Managing Chemicals under TSCA This document is the user guide for the Primary Authorized Official (AO) user of the Section 8(e) Notice tool which is part of the Office of Pollution Prevention and Toxics (OPPT) ‘Section 8(e) Notice’ application submission process. OPPT CCD 1437
Section 8(e) Notice User Guide – Primary Support 2013-10-28 2020-02-28 EPA 705-G-2020-1438 Assessing and Managing Chemicals under TSCA This document is the user guide for the Primary Support user of the Section 8(e) Notice tool which is part of the Office of Pollution Prevention and Toxics (OPPT) ‘Section 8(e) Notice’ application submission process. OPPT CCD 1438
Small Entity Compliance Guidance for the Regulation of Methylene Chloride 2019-09-04 2020-02-28 EPA 705-G-2020-2035 Assessing and Managing Chemicals under TSCA Guide for small business compliance with the regulation of methylene chloride for consumer use. OPPT CCD 2035
Summary of CDR Reporting Requirements by Year 2013-05-01 2020-02-28 EPA 705-G-2020-2268 Chemical Data Reporting This table provides an overview of how the TSCA Inventory Update Reporting (IUR), now called CDR, requirements are changing from the 2006 through the 2016 submission periods. OPPT CCD 2268
Table of Comparison of 2012 CDR v 2006 IUR Definitions 2013-03-25 2020-02-28 EPA 705-G-2020-0457 Chemical Data Reporting In forming 40 CFR 711, EPA sought to simplify the definition section and remove unnecessary duplication of regulatory terms. This table is a comparison of 2006 IUR Definitions and 2012 CDR Definitions. OPPT CCD 457
Test Marketing Exemption (TME) for New Chemical Review under TSCA

2015-08-27

2020-02-28 EPA 705-G-2020-1414 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) Under section 5 of TSCA, EPA established an exemption for certain chemicals that are manufactured (including imported) for test marketing. You can learn more here about the requirements of this exemption, along with the review and submission process. OPPT CCD 1414
TSCA Confidential Business Information 2015-11-09 2020-02-28 EPA 705-G-2020-1487 Assessing and Managing Chemicals under TSCA TSCA 8(e) webpage: TSCA Confidential Business Information - Section 8(e) states that Any person who manufactures a chemical substance and obtains information that the chemical is harmful to health or the environment shall inform the EPA. OPPT CCD 1487
TSCA Import-Export Requirements 2003-06-03 2020-02-28 EPA 705-G-2020-0637 TSCA Import-Export Requirements This website describes various TSCA import and export requirements under TSCA Sections 12 and 13 and implementing sections of the CFR. OPPT CCD 637
TSCA New Chemical Determinations: A Working Approach for Making Determinations under TSCA Section 5 2020-01-02 2020-02-28 EPA 705-G-2020-3601 Chemicals under the Toxic Substances Control Act (TSCA) TSCA New Chemical Determinations: A Working Approach for Making Determinations under TSCA Section 5 OPPT CCD 3601
TSCA Requirements for Exporting Chemicals 2015-09-30 2020-02-28 EPA 705-G-2020-1253 TSCA Import-Export Requirements Describes TSCA import and export requirements under various Sections of TSCA and the CFR. OPPT CCD 1253
TSCA Requirements for Importing Chemicals 2015-09-30 2020-02-28 EPA 705-G-2020-1251 TSCA Import-Export Requirements Describes various TSCA import and export requirements under various Sections of TSCA and the CFR. OPPT CCD 1251
TSCA Section 4(a)(1)(B) Final Statement of Policy; Criteria for Evaluating Substantial Production, Substantial Release, and Substantial or Significant Human Exposure 1993-05-14 2020-02-28 EPA 705-G-2020-0043

Chemicals under the Toxic Substances Control Act (TSCA)

EPA is providing standards and criteria for making findings it will use in implementing its authority under the Toxic Substances Control Act (TSCA) section 4(a)(1)(B). Under this policy, EPA will use as guidance threshold amounts to make “substantial” production, release, and human exposure findings under TSCA section 4(a)(1)(B).

OPPT CCD 43
TSCA Section 4, 8(d), and 8(a) Reporting Webinar 2013-12-12 2020-02-28 EPA 705-G-2020-1453 Assessing and Managing Chemicals under TSCA A webinar presentation demonstrating the TSCA Section 8(a), 8(d) and Section 4 Reporting tool for electronic notice submissions. OPPT CCD 1453
TSCA Section 6 Import/Export Requirements for Specific Chemicals 2015-09-30 2020-02-28 EPA 705-G-2020-1252 TSCA Import-Export Requirements Information on Section 6 of TSCA import and export requirements applicable to certain specific chemicals OPPT CCD 1252
TSCA Section 8(e); Notification of Substantial Risk; Policy Clarification and Reporting Guidance 2003-06-03 2020-02-28 EPA 705-G-2020-0044 Chemicals under the Toxic Substances Control Act (TSCA) The Agency is revising and clarifying certain provisions of the TSCA section 8(e) policy statement issued in 1978. EPA is hereby finalizing revisions to certain parts of EPA’s ‘‘Statement of Interpretation and Enforcement Policy; Notification of Substantial Risk’’ (policy statement) issued March 16, 1978, concerning the reporting of ‘‘substantial risk’’ information pursuant to section 8(e) of the TSCA. OPPT CCD 44
TSCA Section 9 Relationship to Other Federal Laws 2015-09-30 2020-02-28 EPA 705-G-2020-1246 Assessing and Managing Chemicals under TSCA EPA's existing chemicals programs address pollution prevention, risk assessment, hazard and exposure assessment and/or characterization, and risk management for chemicals substances in commercial use. OPPT CCD 1246
What Information Must be Submitted about New Chemical Substances? 2015-09-30 2020-02-28 EPA 705-G-2020-0743 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) This page will give guidance to Premanufacture Notice (PMN) submitters of what information should be provided in their PMN. OPPT CCD 743
XML Schema Guide for Primary CDR Submissions 2012-03-26 2020-02-28 EPA 705-G-2020-0477 Chemical Data Reporting This document presents the extensible markup language (XML) schema guide for the Office of Pollution Prevention and Toxics’ (OPPT) e-CDRweb tool. E-CDRweb is the electronic, web-based tool provided by Environmental Protection Agency (EPA) for the submission of Chemical Data Reporting (CDR) information. This document provides the user with tips and guidance on correctly using the version 1.7 XML schema. Please note that the order of the elements must match the schema. OPPT CCD 477
XML Schema Guide for Secondary CDR Submissions 2012-03-26 2020-02-28 EPA 705-G-2020-0478 Chemical Data Reporting This document presents the extensible markup language (XML) schema guide for the Office of Pollution Prevention and Toxics’ (OPPT) e-CDRweb tool. E-CDRweb is the electronic, web-based tool provided by Environmental Protection Agency (EPA) for the submission of Chemical Data Reporting (CDR) information. This document provides the user with tips and guidance on correctly using the version 1.1 XML schema for the Joint Submission Form. Please note that the order of the elements must match the schema. OPPT CCD 478
Alternatives Assessment Criteria for Hazard Evaluation 2011-08-01 2020-02-28 EPA 705-G-2020-0575 Safer Choice DfE Alternatives Assessments evaluate priority chemicals and functional alternatives with the goal to inform substitution to safer alternatives. OPPT CESSD 575
An Organizational Guide to Pollution Prevention 2001-01-01 2020-02-28 EPA 705-G-2020-0583 Pollution Prevention (P2) This P2 guide provides information to help organizations get P2 programs started or re-evaluate existing programs. OPPT CESSD 583
Certain Chemical Substances Containing Varying Carbon Chain Lengths (Alkyl Ranges Using the Cx-y Notation) on the TSCA Inventory 2017-01-01 2020-02-28 EPA 705-G-2020-2340 TSCA Inventory This paper explains the conventions followed for the purpose of naming and listing certain chemical substances containing ranges of alkyl chain lengths (i.e., carbon chains of varying lengths) for chemical substances on the Toxic Substances Control Act (TSCA) Chemical Substance Inventory. OPPT CESSD 2340
Chemical Nomenclature for Monomer Acid and Derivatives for TSCA Inventory  2001-06-27 2020-02-28 EPA 705-G-2020-2337 TSCA Inventory Corrects a 1985 EPA letter on the chemical nomenclature of monomer acid and derivatives OPPT CESSD 2337
Chemical Substances of Unknown or Variable Composition, Complex Reaction Products and Biological Materials (UVCB Substance) on the TSCA Inventory 2017-01-01 2020-02-28 EPA 705-G-2020-1266 TSCA Chemical Substance Inventory This paper a compendium of information related to the broad class of chemical substances referred to as UVCBs for the Toxic Substances Control Act (TSCA) Chemical Substance Inventory. OPPT CESSD 1266
Collecting and Reporting P2 Results: Regional Measurement Guidance 2014-01-01 2020-02-28 EPA 705-G-2020-1265 Pollution Prevention (P2) Measuring results is an essential component of any successful P2 program and is one way to determine the success of a technical assistance or training effort. This PDF defines some terms of P2 measurement. OPPT CESSD 1265
Combinations of Two or More Substances: Complex Reaction Products on the TSCA Inventory 2017-01-01 2020-02-28 EPA 705-G-2020-2334 TSCA Inventory This paper explains the conventions followed for the purpose of naming and listing reaction product combinations of two or more substances for the Toxic Substances Control Act (TSCA) Chemical Substance Inventory. OPPT CESSD 2334
Criteria for Environmental Toxicity and Fate for Chemicals in Direct Release Products 2015-08-01 2020-02-28 EPA 705-G-2020-3609 Safer Choice This page summarizes criteria for direct release products to help identify those that have preferred environmental toxicity and fate profiles. OPPT CESSD 3609
Criteria for Ice-Melt Products 2015-03-01 2020-02-28 EPA 705-G-2020-3608 Safer Choice The page summarizes criteria for products that melt ice and snow at temperatures below the freezing point of water, and not simply a product that aids traction like sand to help identify those that have preferred human and environmental health profiles. OPPT CESSD 3608
Criteria for Innovative Industrial Product Recognition 2015-03-01 2020-02-28 EPA 705-G-2020-3612 Safer Choice This page summarizes criteria for innovative industrial product recognition, which is applicable when Safer Choice is asked to label a product that replaces a high-profile problematic chemical(s) with a formulation that is significantly safer and high-functioning, but whose ingredients are not limited to chemicals that meet the Criteria for Safer Chemical Ingredients or may not be the safest available because of a need to provide certain critical formulary functionality. OPPT CESSD 3612
Criteria for Inorganic- and Mineral-Based Products 2015-03-01 2020-02-28 EPA 705-G-2020-3611 Safer Choice This page summarizes criteria for inorganic- and mineral-based products to help identify those that have preferred human and environmental health profiles. OPPT CESSD 3611
Criteria for Personal Care Products (PCP) 2015-03-01 2020-02-28 EPA 705-G-2020-3613 Safer Choice This page summarizes criteria for certain classes of personal care products that should be reviewed per Section 4.5 of the Safer Choice Standard. OPPT CESSD 3613
Criteria for Safer Marine Lubricants 2015-03-01 2020-02-28 EPA 705-G-2020-3614 Safer Choice This page summarizes criteria for safer marine lubricants to help identify those that have preferred human and environmental health profiles. OPPT CESSD 3614
EPA Definition of "Pollution Prevention" Memorandum 1992-05-28 2020-02-28 EPA 705-G-2020-1051 Pollution Prevention (P2) EPA Memorandum on defining the term pollution prevention to guide more consistent use of the term in EPA activities and written materials. OPPT CESSD 1051
Frequently Asked Questions 2016-02-01 2020-02-28 EPA 705-G-2020-3604 Safer Choice This list of frequently asked questions is intended to answer many of the common questions that website users have about the program. OPPT CESSD 3604
Guidance for Creating Generic Names for Confidential Chemical Substance Identity Reporting under TSCA 2018-06-01 2020-02-28 EPA 705-G-2020-1419 TSCA Chemical Substance Inventory Guidance for creating generic names for chemical substances whose specific chemical identities are claimed confidential in TSCA notices OPPT CESSD 1419
How to Add a New Sector 2015-03-01 2020-02-28 EPA 705-G-2020-3606 Safer Choice This page contains steps for companies interested in developing a new product sector, or class of products, that Safer Choice has not previously labeled. OPPT CESSD 3606
How to Conduct an Alternatives Assessment 2015-03-01 2020-02-28 EPA 705-G-2020-3620 Alternatives Assessment This page summarizes the steps for conducting a chemical alternatives assessment. OPPT CESSD 3620
How to List a Chemical on the Safer Chemical Ingredients List 2015-03-01 2020-02-28 EPA 705-G-2020-1238 Safer Choice Instructions on how to get a chemical listed on the Safer Chemical Ingredients List OPPT CESSD 1238
Isotopes on the TSCA Inventory 2013-06-19 2020-02-28 EPA 705-G-2020-2335 TSCA Inventory This fact sheet provides guidance on reporting chemical substances that have different isotopes of the same element or the isotopic composition of a constituent element has been intentionally changed from the naturally‐occurring isotopic composition.  OPPT CESSD 2335
Nanoscale Substances on the TSCA Inventory 2008-01-23 2020-02-28 EPA 705-G-2020-2338 TSCA Inventory This document provides guidance on how EPA currently determines whether a nanoscale substance is a “new” chemical for the purposes of the Toxic Substances Control Act (TSCA) Inventory.   OPPT CESSD 2338
Polymeric Substances on the TSCA Inventory 2017-01-01 2020-02-28 EPA 705-G-2020-2339 TSCA Inventory This paper explains the conventions followed for the purpose of naming and listing polymeric chemical substances on the Toxic Substances Control Act (TSCA) Chemical Substance Inventory. OPPT CESSD 2339
Products Containing Two or More Substances, Formulated and Statutory Mixtures on the TSCA Inventory 2017-01-01 2020-02-28 EPA 705-G-2020-2336 TSCA Inventory This paper explains the conventions followed for the purpose of naming and listing certain mixtures for the Toxic Substances Control Act (TSCA) Chemical Substance Inventory. OPPT CESSD 2336
Resources for Safer Choice Product Manufacturers 2015-03-01 2020-02-28 EPA 705-G-2020-0613 Safer Choice A portal to help Safer Choice partners locate technical and other information most relevant to their operations OPPT CESSD 613
Safer Choice Communities & Municipalities Fact Sheet 2016-10-18 2020-02-28 EPA 705-G-2020-3616 Safer Choice This fact sheet includes basic information about the Safer Choice program, and how communities and municipalities can identify Safer Choice-certified products. OPPT CESSD 3616
Safer Choice Criteria for Chelating and Sequestering Agents 2015-03-01 2020-02-28 EPA 705-G-2020-0580 Safer Choice DfE defined specific criteria for chelating and sequestering agents to help identify those that have preferred human and environmental health profiles OPPT CESSD 580
Safer Choice Criteria for Colorants, Polymers, Preservatives, and Related Chemicals 2015-03-01 2020-02-28 EPA 705-G-2020-0577 Safer Choice DfE has defined specific criteria for determining whether a colorant, polymer, preservative, or related chemical can be considered a safer chemical ingredients under the DfE program OPPT CESSD 577
Safer Choice Criteria for Defoamers 2015-03-01 2020-02-28 EPA 705-G-2020-1538 Safer Choice DfE has defined specific criteria for determining whether a defoamer can be considered a safer chemical ingredients under the DfE program OPPT CESSD 1538
Safer Choice Criteria for Enzymes and Enzyme Stabilizers 2015-03-01 2020-02-28 EPA 705-G-2020-0578 Safer Choice DfE defines specific criteria that determine whether enzymes and enzyme stabilizers are safer chemical ingredients within the DfE program OPPT CESSD 578
Safer Choice Criteria for Formulations Containing Microorganisms 2015-03-01 2020-02-28 EPA 705-G-2020-0570 Safer Choice Safer Choice considers both human health and environmental concerns when evaluating formulations containing microorganisms. OPPT CESSD 570
Safer Choice Criteria for Fragrance-Free Products 2016-02-01 2020-02-28 EPA 705-G-2020-1243 Safer Choice Safer Choice has developed criteria for fragrance-free products to allow them to add the fragrance-free notation with the Safer Choice label. OPPT CESSD 1243
Safer Choice Criteria for Fragrances 2015-12-01 2020-02-28 EPA 705-G-2020-0581 Safer Choice DfE developed its criteria for fragrances with a group of stakeholders that included the fragrance industry, formulators, and NGOs OPPT CESSD 581
Safer Choice Criteria for Oxidants and Oxidant Stabilizers 2015-03-01 2020-02-28 EPA 705-G-2020-0579 Safer Choice DfE defines specific criteria for determining whether an oxidant or oxidant stabilizer can be considered a safer chemical ingredient under the DfE program OPPT CESSD 579
Safer Choice Criteria for Processing Aids and Additives 2015-03-01 2020-02-28 EPA 705-G-2020-0582 Safer Choice Safer Choice created specific criteria for processing aids and additives to allow for tailored human and environmental health criteria for this class of chemicals OPPT CESSD 582
Safer Choice Criteria for Solvents 2015-03-01 2020-02-28 EPA 705-G-2020-0588 Safer Choice Safer Choice focuses on characteristics most relevant to solvents used in cleaners to help distinguish safer solvents from those of greater concern OPPT CESSD 588
Safer Choice Criteria for Specialized Industrial Products 2015-02-01 2020-02-28 EPA 705-G-2020-0569 Safer Choice Safer Choice has created a specific criteria for specialized industrial products to account for distinct performance requirements not applicable to other I/I products. OPPT CESSD 569
Safer Choice Criteria for Surfactants 2016-04-01 2020-02-28 EPA 705-G-2020-3607 Safer Choice This page summarizes criteria for surfactants to help identify those that have preferred human and environmental health profiles. OPPT CESSD 3607
Safer Choice Fragrance-Free Fact Sheet 2016-10-18 2020-02-28 EPA 705-G-2020-3617 Safer Choice This fact sheet describes the Safer Choice fragrance-free certification and provides additional resources. OPPT CESSD 3617
Safer Choice General Consumer Fact Sheet 2016-10-18 2020-02-28 EPA 705-G-2020-3619 Safer Choice This fact sheet includes basic information about the Safer Choice program, and how consumers can identify Safer Choice-certified products. OPPT CESSD 3619
Safer Choice Guidance for Ingredient Disclosure Requirements 2016-06-01 2020-02-28 EPA 705-G-2020-1247 Safer Choice Guidance on how to meet the ingredient disclosure requirements for the Safer Choice Program OPPT CESSD 1247
Safer Choice Guidance for Packaging Requirements 2015-03-01 2020-02-28 EPA 705-G-2020-1248 Safer Choice Guidance on how to meet the packaging requirements for the Safer Choice Program OPPT CESSD 1248
Safer Choice Implementation and Compliance Schedules 2019-04-01 2020-02-28 EPA 705-G-2020-0568 Safer Choice DfE has established implementation and compliance schedules for the Safer Product Labeling Program OPPT CESSD 568
Safer Choice Master Criteria for Safer Chemical Ingredients 2012-09-01 2020-02-28 EPA 705-G-2020-0567 Safer Choice The DfE Criteria for Safer Ingredients were established to ensure that the safest possible ingredients are used in DfE-labeled products in the DfE Safer Products Labeling Program. OPPT CESSD 567
Safer Choice Resources for Manufacturers Fact Sheet 2017-10-01 2020-02-28 EPA 705-G-2020-3618 Safer Choice This fact sheet provides resources for manufacturers formulating products with safer chemical ingredients. OPPT CESSD 3618
Safer Choice Schools Fact Sheet 2016-10-18 2020-02-28 EPA 705-G-2020-3615 Safer Choice This fact sheet includes basic information about the Safer Choice program, and how school purchasers and consumers can identify Safer Choice-certified products. OPPT CESSD 3615
Safer Choice Standard 2015-02-01 2020-02-28 EPA 705-G-2020-0566 Safer Choice; FIFRA; Pesticides; Antimicrobial; The Safer Choice Standard was developed with the purpose of making criteria for recognition under the Safer Choice Program more transparent and accessible. OPPT CESSD 566
Third-Party Profiler Qualifications for the Safer Choice Program 2015-03-01 2020-02-28 EPA 705-G-2020-0576 Safer Choice DfE has set stringent requirements for candidates seeking to become a qualified third-party profiler OPPT CESSD 576
Fees for the Administration of the Toxic Substances Control Act 2018-10-01 2020-02-28 EPA 705-G-2020-1757 TSCA Administration Fees Overview of the TSCA administration fees rule, including the rule's history and what activities are covered under the rule. OPPT EAD 1757
Access to Toxic Substances Control Act Confidential Business Information: A guide for access to TSCA CBI for medical and environmental professionals in non-emergency situations 2018-06-27 2020-02-28 EPA 745-B-18-002 Requesting Access to CBI under TSCA A guide for access to TSCA CBI for medical and environmental professionals in non-emergency situations under TSCA section 14(d). OPPT IMD 4
Access to Toxic Substances Control Act Confidential Business Information: A guide for access to TSCA CBI for state, local, and tribal governments 2018-06-27 2020-02-28 EPA 745-B-18-001 Requesting Access to CBI under TSCA A guide for access to TSCA CBI for state, local, and tribal governments under TSCA section 14(d). OPPT IMD 5
Access to Toxic Substances Control Act Confidential Business Information: A guide for access to TSCA CBI in emergency situations 2018-06-27 2020-02-28 EPA 745-B-18-003 Requesting Access to CBI under TSCA A guide for access to TSCA CBI in emergency situations under TSCA section 14(d). OPPT IMD 3
CSPP CDX Registration Guide 2012-03-16 2020-02-28 EPA 705-G-2020-0472 Chemical Data Reporting CDX allows users submitting data to the EPA to register for the specific program of interest. This Guide describes the registration process and information requirements associated with Submissions for the Chemical Safety and Pesticide Programs (CSPP). OPPT IMD 472
e-CDRweb User Roles 2013-05-01 2020-02-28 EPA 705-G-2020-2279 Chemical Data Reporting This document outlines the roles of the persons involved in the submission of data for Chemical Data Reporting. OPPT IMD 2279
EPA Review and Determination of CBI Claims under TSCA 2019-12-03 2020-02-28 EPA 705-G-2020-1654 Confidential Business Information under TSCA Companies reporting information to EPA may request it be treated as Confidential Business Information (CBI) OPPT IMD 1654
Making CBI Claims in TSCA Submissions 2019-08-13 2020-02-28 EPA 705-G-2020-1650 Confidential Business Information under TSCA Companies reporting information to EPA may request it be treated as Confidential Business Information (CBI). OPPT IMD 1650
Policies for Deficient TSCA CBI Submissions 2019-08-13 2020-02-28 EPA 705-G-2020-1745 Confidential Business Information under TSCA Describes EPA's policies related to deficient TSCA CBI submissions OPPT IMD 1745
Requesting Access to CBI under TSCA 2018-07-09 2020-02-28 EPA 705-G-2020-1735 Confidential Business Information under TSCA Description of Confidential Business Information under TSCA OPPT IMD 1735
Statutory Requirements for Substantiation of Confidential Business Information (CBI) Claims Under the Toxic Substances Control Act (TSCA) 2019-07-16 2020-02-28 EPA-HQ-OPPT-2017-0026 TSCA, CBI, Substantiation, Notice of deficiency EPA announced revised policy and that it would cease sending non-statutorily required notices of deficiency to businesses who submit procedurally flawed CBI claims. OPPT IMD 3290
Statutory Requirements for Substantiation of Confidential Business Information Claims Under Toxic Substances Control Act 2017-01-19 2020-02-28 EPA-HQ-OPPT-2017-0026-0001 TSCA, CBI, substantiation EPA is interpreting the revised TSCA section 14(c)(3) as requiring substantiation of all CBI claims at the time the information claimed as CBI is submitted to EPA, except for claims for information subject to TSCA section 14(c)(2). This action facilitates the Agency's implementation of TSCA section 14(g) to review all CBI claims for chemical identity, with limited exceptions, as well as to review a representative sample of at least 25% of other non-exempt claims. OPPT IMD 3289
Substantiating CBI Claims under TSCA at the Time of Initial Submission 2019-01-17 2020-02-28 EPA 705-G-2020-1651 Confidential Business Information under TSCA Companies reporting information to EPA may request it be treated as Confidential Business Information (CBI) OPPT IMD 1651
TSCA CBI Protection Manual 2004-01-28 2020-02-28 69 FR 20007 TSCA, CBI, Manual

Manual applying to all federal employees, contractors, and contractor employees with access to information claimed as Toxic Substances Control Act (TSCA) Confidential Business Information (CBI) in connection with either their official duties or with a TSCA-related government contract, as stated in Section 14(a) of TSCA. The following general subjects correspond to the chapters in this Manual: 1) Steps necessary to become authorized for access to TSCA CBI. 2) Relative roles and responsibilities regarding TSCA CBI. 3) Steps for use and protection of TSCA CBI. 4) Procedures in cases of lost or improperly disclosed TSCA CBI.

OPPT IMD 3282
TSCA CBI Training - Introduction 2019-11-18 2020-02-28 EPA 705-G-2020-1859 Confidential Business Information under TSCA Anyone who uses TSCA CBI must obtain clearance to do so every year. This course will serve as your yearly obligatory CBI training. OPPT IMD 1859
TSCA Chemical Substances: Unique Identifier Assignment and Application Policy 2018-06-27 2020-02-28 EPA-HQ-OPPT-2017-0144 TSCA, CBI, Unique Identifier, UID EPA announcing that it will use a numerical identifier that incorporates the year the CBI claim was asserted, and will apply this UID to non-confidential information related to the chemical substance, except where the Agency's act of applying the UID would itself disclose to the public the confidential specific chemical identity that the UID was assigned to protect. OPPT IMD 3291
Webinars on the TSCA Administration Fees Rule 2018-10-01 2020-02-28 EPA 705-G-2020-1759 TSCA Administration Fees Information on webinars related to the TSCA Administrative fees rule. OPPT IMD 1759
What to Include in CBI Substantiations 2019-08-13 2020-02-28 EPA 705-G-2020-1653 Confidential Business Information under TSCA Companies reporting information to EPA may request it be treated as Confidential Business Information (CBI) OPPT IMD 1653
1994 PCB Question and Answer Manual 1994-01-01 2020-02-28 EPA 705-G-2020-0001 PCBs An EPA TSCA assistance document designed to provide the regulated community with Agency interpretations to frequently posed questions. OPPT NPCD 1
2001 Polychlorinated Biphenyl (PCB) Question and Answer Document  2001-09-01 2020-02-28 EPA 705-G-2020-0002 PCBs The PCB Q and A manual is a living document and is periodically revised and updated. The updates are posted on the EPA PCB web site at http://www.epa.gov/pcb for our customer’s use. Current version is the June 2014 update. OPPT NPCD 2
Acquisition of a decommissioned naval vessel from MARAD of Guam 1999-05-03 2020-02-28 EPA 705-G-2020-3395 PCBs Guidance on the applicability of the PCB regulations to the export for reuse of decommissioned naval vessels which contains non-liquid PCBs. OPPT NPCD 3395
Actions for Reducing Exposures to PCBs in Indoor Building Environments 1 2015-07-28 2020-02-28 EPA 705-G-2020-2308 PCBs PCBs in Building Materials Diagram (chart 1). OPPT NPCD 2308
Actions for Reducing Exposures to PCBs in Indoor Building Environments 2 2015-07-28 2020-02-28 EPA 705-G-2020-2309 PCBs PCBs in Building Materials Diagram (chart 2). OPPT NPCD 2309
Agreement Between The Department of the Navy and The United States Environmental Protection Agency 1996-08-19 2020-02-28 EPA 705-G-2020-3401 PCBS Agreement Between The Department of the Navy and The United States Environmental Protection Agency (OECA) on the use of Naval Vessels containing PCBs as targets and test platforms resulting in their sinking (SINKEX). OPPT NPCD 3401
AHERA Asbestos Management Plan Self-Audit Checklist for Designated Persons 2013-03-05 2020-02-28 EPA 705-G-2020-0439 Asbestos This Environmental Protection Agency (EPA) manual helps the AHERA Designated Person to understand whether their school has an up-to-date compliant Asbestos Management Plan (AMP). OPPT NPCD 439
AHERA Interpretation On Learning Centers 2008-06-27 2020-02-28 EPA 705-G-2020-3154 Asbestos Guidance on whether learning centers are subject to the requirements under the Asbestos Hazard Emergency Response Act (AHERA) and the Asbestos-Containing Materials in Schools Rule. OPPT NPCD 3154
AHERA Policy Clarification on Vinyl Asbestos Tile (VAT) Removal, July 15, 1992 1992-07-05 2020-02-28 EPA 705-G-2020-2765 Asbestos Final policy clarification on Vinyl Asbestos Tile (VAT) removal under AHERA produced by the AHERA Interpretive Guidance Workgroup OPPT NPCD 2765
Annual Report Submission for Third Party Certifiers - Formaldehyde Emission Standards for Composite Wood Products 2016-07-05 2020-02-28 EPA 705-G-2020-2194 TSCA Title VI, Composite wood products, formaldehyde Presentation slides for submitting the Third Party Certifier Annual Report under the TSCA Title VI program in the Central Data Exchange system OPPT NPCD 2194
Answer to request for confirmation of understanding of the PCB regulations 1990-07-20 2020-02-28 EPA 705-G-2020-3453 PCBs Answer to request for confirmation of understanding of the PCB regulations. Permissible to reuse containers for disposal activities without decontamination between uses. OPPT NPCD 3453
Answers to the Most Frequently Asked Questions about Reinspections 1991-05-01 2020-02-28 EPA 705-G-2020-2741 Asbestos; inspections  Q/A about asbestos reinspections OPPT NPCD 2741
Applicability of AHERA to Newly Installed Building Materials 2008-10-01 2020-02-28 EPA 705-G-2020-3153 Asbestos Applicability of AHERA to Newly Installed Building Materials OPPT NPCD 3153
Applicability of the "food and feed" requirements of the EPA's PCB regulations to the manufacture of teabags and other food-contact filter paper 1985-09-20 2020-02-28 EPA 705-G-2020-3411 PCBs Guidance on Applicability of the "food and feed" requirements of the EPA's PCB regulations to the manufacture of teabags and other food-contact filter paper. As with FDA food contact materials, these are not subject to ban unless food itself present. OPPT NPCD 3411
Application Process for Accreditation Bodies - Formaldehyde Emission Standards for Composite Wood Products 2016-07-05 2020-02-28 EPA 705-G-2020-2192 TSCA Title VI, Composite wood products, formaldehyde Presentation slides for applying to the EPA to become a recognized Accreditation Body under the TSCA Title VI program in the Central Data Exchange system OPPT NPCD 2192
Application Process for Third Party Certifiers - Formaldehyde Emission Standards for Composite Wood Products 2016-07-05 2020-02-28 EPA 705-G-2020-2193 TSCA Title VI, Composite wood products, formaldehyde Presentation slides for applying to the EPA to become a recognized Third Party Certifier under the TSCA Title VI program in the Central Data Exchange system OPPT NPCD 2193
Asbestos and School Buildings 2013-03-05 2020-02-28 EPA 705-G-2020-0448 Asbestos Federal requirements under the Asbestos Hazard Emergency Response Act (AHERA) OPPT NPCD 448
Asbestos Hazard Emergency Response Act (AHERA) Inspection Guidance Manual and Checklist 1992-08-01 2020-02-28 EPA 705-G-2020-2745 Asbestos; AHERA Guidance manual and general checklist for the Asbestos Hazard Emergency Response Act (AHERA)  OPPT NPCD 2745
Asbestos in Buildings: Guidance for Service and Maintenance Personnel 1985-07-01 2020-02-28 EPA 705-G-2020-2715 Asbestos; buildings; Guidance for service and maintenance personnel in buildings containing asbestos OPPT NPCD 2715
Asbestos Professionals 2013-03-05 2020-02-28 EPA 705-G-2020-0450 Asbestos How to become a trained and accredited asbestos professional and find labs for testing asbestos. OPPT NPCD 450
Asbestos Sampling Bulletin Supplementary Guidance on Bulk Sample Collection and Analysis 1994-09-30 2020-02-28 EPA 705-G-2020-2743 Asbestos; sampling  Guidance on bulk sample collection and analysis of asbestos  OPPT NPCD 2743
Asbestos Waste Management Guidance: Generation, Transport, Disposal 1985-05-01 2020-02-28 EPA 705-G-2020-2714 Asbestos Guidance for asbestos waste management including generation, transport, and disposal OPPT NPCD 2714
Asbestos/NESHAP Adequately Wet Guidance 1990-12-01 2020-02-28 EPA 705-G-2020-2717 Asbestos; NESHAP Guidance for asbestos/NESHAP adequately wet OPPT NPCD 2717
Asbestos/NESHAP Regulated Asbestos Containing Materials Guidance 1990-12-01 2020-02-28 EPA 705-G-2020-2713 Asbestos; NESHAP; asbestos containing materials Guidance for asbestos/ NESHAP regulated asbestos containing materials OPPT NPCD 2713
Assessment and Control of Chrysotile Asbestos Emissions from Unpaved Roads 1981-05-01 2020-02-28 EPA 705-G-2020-2701 Asbestos; emission; roadways Assessment and Control of Chrysotile Asbestos Emissions from Unpaved Roads OPPT NPCD 2701
Assistance in returning Hazardous Waste Shipment From Canada to U.S. 2000-07-31 2020-02-28 EPA 705-G-2020-3497 PCBs EPA guidance to Environment Canada on determination that unauthorized shipments of PCB waste to Canada may be returned to the United States for disposal. OPPT NPCD 3497
Assumptions about a PCB-Contaminated Transformer 1999-03-16 2020-02-28 EPA 705-G-2020-3482 PCBs Guidance on the applicability of the  761.2 PCB concentration assumptions to pole top and pad mount mineral oil transformers in use and for servicing. OPPT NPCD 3482
Best management practices for lead outdoor shooting ranges, EPA-902-B-01-001, Revised June 2005 2005-06-01 2020-02-28 EPA 705-G-2020-0395 Lead This manual provides owners and operators of outdoor rifle, pistol, trap, skeet and sporting clay ranges with information on lead management at their ranges. OPPT NPCD 395
Brewery for tourists considered commercial building under 40 CFR Part 761 1989-05-03 2020-02-28 EPA 705-G-2020-3446 PCBs EPA guidance on whether public tours affect a facility's industrial non-commercial building status for the PCB fire regulations. OPPT NPCD 3446
Bushings; In use and at the time of disposal 1993-05-27 2020-02-28 EPA 705-G-2020-3472 PCBs EPA policy on bushings with PCBs not otherwise authorized in regulations: bushings in service on authorized transformers are treated as having the same concentration as the transformer. OPPT NPCD 3472
CATAIR EPA Supplemental Guidelines 2019-11-06 2020-02-28 EPA 705-G-2020-2199 TSCA Title VI, import certification, Section 13, composite wood product Includes guidance for completing TSCA Section 13 import certification under the TSCA Title VI program OPPT NPCD 2199
CATAIR EPA Supplemental Guidelines 2019-11-06 2020-02-28 EPA 705-G-2020-2298 TSCA title VI, import certification, Section 13, composite wood product Includes guidance for completing TSCA Section 13 import certification under the TSCA Title VI program OPPT NPCD 2298
CBP and Trade Automated Interface Requirements 2019-01-29 2020-02-28 EPA 705-G-2020-2198 TSCA Title VI, Section 13, import certification, composite wood Includes guidance for completing TSCA Section 13 import certification under the TSCA Title VI program OPPT NPCD 2198
CBP and Trade Automated Interface Requirements 2019-01-29 2020-02-28 EPA 705-G-2020-2297 TSCA Section 13, import certification, TSCA Title VI, composite wood,  Includes guidance for completing TSCA Section 13 import certification under the TSCA Title VI program OPPT NPCD 2297
Clarification of AHERA regulations regarding schools in which no asbestos-containing building material (ACBM) is present 1989-05-24 2020-02-28 EPA 705-G-2020-3228 Asbestos Clarification of AHERA regulations regarding schools in which no asbestos-containing building material (ACBM) is present; 5-7-90 Confirmation of information provided verbally in response to a letter requesting verification of the Pennsylvania Department of Environmental Resources’ interpretation of AHERA reinspection requirement; 7-2-90 Response to inquiry about the applicability of AHERA reinspection requirements to buildings in which all ACBM has been removed OPPT NPCD 3228
Clarification of current EPA policy requiring all non-Worker training courses to be provided in the English language 1990-07-26 2020-02-28 EPA 705-G-2020-3215 Asbestos Clarification of current EPA policy requiring all non-Worker training courses to be provided in the English language OPPT NPCD 3215
Clarification of EPA’s requirements relating to AHERA training course instructor qualifications, sent in response to an inquiry dated 10/15/93; notes that very little written guidance exists 1993-10-26 2020-02-28 EPA 705-G-2020-3183 Asbestos Clarification of EPA’s requirements relating to AHERA training course instructor qualifications, sent in response to an inquiry dated 10/15/93; notes that very little written guidance exists OPPT NPCD 3183
Clarification of Importation of PCBs 1990-09-24 2020-02-28 EPA 705-G-2020-3456 PCBs Clarification of Importation of PCBs OPPT NPCD 3456
Clarification of the applicability of AHERA to custodial employees who are not hired directly by a Local Education Agency (LEA) 1990-08-20 2020-02-28 EPA 705-G-2020-3209 Asbestos Clarification of the applicability of AHERA to custodial employees who are not hired directly by a Local Education Agency (LEA) but are hired by an operating engineer at each school within the district; 5-12-95 Response to request for guidance regarding the disposition, retention, and archiving of obsolete Asbestos Management Plans OPPT NPCD 3209
Clarification of the inspection exclusion provided in AHERA for new schools built after October 12, 1988, in which no ACBM was used as a building material 1988-05-24 2020-02-28 EPA 705-G-2020-3238 Asbestos Clarification of the inspection exclusion provided in AHERA for new schools built after October 12, 1988, in which no ACBM was used as a building material. OPPT NPCD 3238
Clarification of whether the Asbestos MAP permits accredited Contractor/Supervisors to exchange that accreditation for Worker accreditation without further training; attached to facsimile transmittal sheet dated 12/29/97 1997-10-27 2020-02-28 EPA 705-G-2020-3168 Asbestos Clarification of whether the Asbestos MAP permits accredited Contractor/Supervisors to exchange that accreditation for Worker accreditation without further training; attached to facsimile transmittal sheet dated 12/29/97. OPPT NPCD 3168
Clarification of whether the Asbestos Model Accreditation Plan (MAP) requires that a design plan be prepared by an accredited project designer prior to the commencement of covered response actions in a school or in a public or commercial building; 1994-06-23 2020-02-28 EPA 705-G-2020-3177 Asbestos Clarification of whether the Asbestos Model Accreditation Plan (MAP) requires that a design plan be prepared by an accredited project designer prior to the commencement of covered response actions in a school or in a public or commercial building. OPPT NPCD 3177
Clarification of why the EPA does not allow training providers to combine the “worker” refresher requirements with the “contractor/supervisor” refresher requirements into a combined refresher course 1990-08-17 2020-02-28 EPA 705-G-2020-3210 Asbestos Clarification of why the EPA does not allow training providers to combine the “worker” refresher requirements with the “contractor/supervisor” refresher requirements into a combined refresher course. OPPT NPCD 3210
Clarifications on the recent amendments to the "Uncontrolled Rule" 1989-01-04 2020-02-28 EPA 705-G-2020-3444 PCBs Clarifications on the recent amendments to the "Uncontrolled Rule". Guidance on how to interpret "source of the products" in the Excluded PCB Products definition at 761.3. OPPT NPCD 3444
Classification of a "Cincinnati" machine tool and insulated electric cable and wiring as excluded PCB products 1994-03-11 2020-02-28 EPA 705-G-2020-3476 PCBs Guidance on the status of machine lathes with surface contamination and insulated electric cable and wiring as excluded PCB products. OPPT NPCD 3476
Comments on American Gas Association's summarization of EPA question and answer session 1999-02-01 2020-02-28 EPA 705-G-2020-3495 PCBs EPA final guidance Q&A on PCB natural gas pipeline questions posed by AGA. OPPT NPCD 3495
Common Questions on the Asbestos NESHAP 1990-12-01 2020-02-28 EPA 705-G-2020-2722 Asbestos; NESHAP Q/A on asbestos as it relates to NESHAP OPPT NPCD 2722
Completing Regional Review of Courses Submitted Under the AHERA Model Accreditation Plan 1987-09-17 2020-02-28 EPA 705-G-2020-3239 Asbestos Completing Regional Review of Courses Submitted Under the AHERA Model Accreditation Plan OPPT NPCD 3239
Compliance Guide; Reporting Requirements for the Mercury Inventory of the Toxic Substances Control Act, 2018 2019-03-15 2020-02-28 EPA 705-G-2020-2184 Mercury inventory reporting; elemental mercury; mercury compounds Guidance for private industry on submitting information to Mercury Inventory Reporting OPPT NPCD 2184
Compliance Guide; Reporting Requirements for the Mercury Inventory of the Toxic Substances Control Act, 2018 2019-03-15 2020-02-28 EPA 705-G-2020-2405 Mercury inventory reporting Assistance for reporters on Mercury Inventory Reporting OPPT NPCD 2405
Confirmation regarding regulatory status of shunt and series reactors 2000-08-22 2020-02-28 EPA 705-G-2020-3396 PCBs Guidance that shunt and series reactors may be managed in accordance with transformer provisions at 761.30. OPPT NPCD 3396
Court Order; Formaldehyde Emission Standards for Composite Wood Products 2018-04-04 2020-02-28 EPA 705-G-2020-2299 TSCA Title VI, compliance date, Section 13, composite wood product Federal Register Notice of the Court Decision related to the extension of the compliance dates under the Formaldehyde Emission Standards for Composite Wood Products regulation. OPPT NPCD 2299
Current Best Practices for Preventing Asbestos Exposure Among Brake and Clutch Repair Workers 2013-03-05 2020-02-28 EPA 747-F-04-004 Asbestos Brochure for professional and home mechanics. OPPT NPCD 441
Current Best Practices for Preventing Asbestos Exposure Among Brake and Clutch Repair Workers 2013-03-05 2020-02-28 EPA 747-F-04-004 Asbestos Guidance on preventing Asbestos Exposure Among Brake and Clutch Workers OPPT NPCD 446
Definitions of network and radial transformers referenced in the 1985 PCB transformer fires rule 1986-04-22 2020-02-28 EPA 705-G-2020-3427 PCBs Detailed guidance on network and radial definitions and applicability to spot networks. OPPT NPCD 3427
Discharges of recycled PCBs to water 1984-08-16 2020-02-28 EPA 705-G-2020-3403 PCBs Guidance on the 761.3 definition for recycled PCBs; where to sample for measuring water discharges.  PCB use exclusions guidance; not a disposal regulation. OPPT NPCD 3403
Distribution in commerce of drained electrical equipment  and parts 2002-01-15 2020-02-28 EPA 705-G-2020-3500 PCBs EPA guidance updates on the distribution in commerce of drained electrical equipment  and parts for disposal and use. OPPT NPCD 3500
Elements of an Asbestos Operations and Maintenance (O&M) Program 2016-12-20 2020-02-28 EPA 705-G-2020-2207 Asbestos  Designing and asbestos operations and maintenance program. OPPT NPCD 2207
Environmental Asbestos Assessment Manual, Superfund Method for the Determination of Asbestos in Ambient Air, Part 1: Method 1999-02-01 2020-02-28 EPA 705-G-2020-2695 Asbestos Manual for Environmental Asbestos Assessment. OPPT NPCD 2695
Environmental Asbestos Assessment Manual, Superfund Method for the Determination of Asbestos in Ambient Air, Part 2: Technical Background Document 1999-02-01 2020-02-28 EPA 705-G-2020-2696 Asbestos Manual for Environmental Asbestos Assessment. OPPT NPCD 2696
EPA Asbestos Materials Bans: Clarification 1999-05-18 2020-02-28 EPA 705-G-2020-2734 Asbestos Clarification on banning materials containing asbestos. OPPT NPCD 2734
EPA Certification Program: Fees for Renovation Firms and Abatement Firms 2008-01-01 2020-02-28 EPA 705-G-2020-2329 Lead Refund policy for renovation and abatement firms. OPPT NPCD 2329
EPA Guidelines for States Regarding Online Asbestos Model Accreditation Plan (MAP) Annual Refresher Training 2007-06-09 2020-02-28 EPA 705-G-2020-2203 Asbestos Guidelines for states on pursuing online training under the asbestos model accreditation plan. OPPT NPCD 2203
EPA Lead-Based Paint Program Frequent Questions 2018-03-22 2020-02-28 EPA 705-G-2020-0528 Lead EPA's Lead-Based Paint Program frequent questions. OPPT NPCD 528
EPA Model Lead-Based Paint Abatement Worker Training Course 2004-03-01 2020-02-28 EPA 705-G-2020-2323 Lead EPA Model Worker Course: Residential Lead-Based Paint Abatement - March 2004 OPPT NPCD 2323
EPA's interpretation of the scope of the PCB large capacitor phase-out requirements 1988-12-30 2020-02-28 EPA 705-G-2020-3442 PCBs EPA's interpretation of the scope of the PCB large capacitor phase-out requirements. Restricted access does not refer to a capacitors specific location within a building with general restricted public access. OPPT NPCD 3442
Excluded PCB Products - painted machines 1997-05-12 2020-02-28 EPA 705-G-2020-3480 PCBs Guidance on Excluded PCB Products - items coated with paints which contain <50 ppm PCBs meet the definition of excluded PCB products if the contamination came from historic uses. OPPT NPCD 3480
Exemption to buy or sell PCB or PCB-contaminated transformers 1990-08-28 2020-02-28 EPA 705-G-2020-3454 PCBs EPA guidance that an exemption to buy or sell PCB or PCB-contaminated transformers is not required for intact non-leaking equipment that complies with 761.20(c)(1). OPPT NPCD 3454
Export for reuse of transformers <50ppm 1991-08-23 2020-02-28 EPA 705-G-2020-3460 PCBs Guidance on export for reuse of transformers <50ppm PCBs as excluded PCB products. OPPT NPCD 3460
Export for reuse of transformers <50ppm 1991-08-23 2020-02-28 EPA 705-G-2020-3461 PCBs Guidance on export for reuse of transformers <50ppm PCBs as excluded PCB products. OPPT NPCD 3461
Export of small PCB Capacitors, General Motors 1991-08-06 2020-02-28 EPA 705-G-2020-3459 PCBs Interpretive statement on export of pre-July 1, 1979, intact non-leaking PCB electrical equipment under TSCA section 6(e). Exemption not required. OPPT NPCD 3459
Exporting Transformers to India/Pakistan 1992-09-24 2020-02-28 EPA 705-G-2020-3466 PCBs Guidance on exporting  >50 ppm PCB transformers for reuse. OPPT NPCD 3466
Federal Requirements For Asbestos Management in Schools Fact Sheet 2013-03-05 2020-02-28 EPA 705-G-2020-0451 Asbestos This Environmental Protection Agency (EPA) pamphlet can help parents and teachers answer questions and learn the facts about asbestos and its regulations in schools. OPPT NPCD 451
Follow-up Memo on Issues Raised by Regional Staff during the June 25 Conf. Call Regarding Accreditation 1987-07-24 2020-02-28 EPA 705-G-2020-3240 Asbestos Follow-up Memo on Issues Raised by Regional Staff during the June 25 Conf. Call Regarding Accreditation OPPT NPCD 3240
For Accreditation Bodies and Third-Party Certifiers - Compliance Guide for Formaldehyde Emission Standards for Composite Wood, with Translations 2016-06-01 2020-02-28 EPA 705-G-2020-1691 Formaldehyde This page provides resources and guidance documents, including translations, and pertaining to the Formaldehyde Emissions Standards for Composite Wood Products Final Rule. OPPT NPCD 1691
For Fabricators and Laminated Product Producers - Compliance Guide for Formaldehyde Emission Standards for Composite Wood, with Translations 2016-06-01 2020-02-28 EPA 705-G-2020-1692 Formaldehyde This page provides resources and guidance documents, including translations, and pertaining to the Formaldehyde Emissions Standards for Composite Wood Products Final Rule. OPPT NPCD 1692
For Importers, Distributors, and Retailers - Compliance Guide for Formaldehyde Emission Standards for Composite Wood, with Translations 2016-06-01 2020-02-28 EPA 705-G-2020-1690 Formaldehyde This page provides resources and guidance documents, including translations, and pertaining to the Formaldehyde Emissions Standards for Composite Wood Products Final Rule. OPPT NPCD 1690
For Mills - Compliance Guide for Formaldehyde Emission Standards for Composite Wood, with Translations 2016-06-01 2020-02-28 EPA 705-G-2020-1689 Formaldehyde This page provides resources and guidance documents, including translations, and pertaining to the Formaldehyde Emissions Standards for Composite Wood Products Final Rule. OPPT NPCD 1689
Formaldehyde Emissions from Pressed Wood Products 2017-01-01 2020-02-28 EPA 705-G-2020-0048 Formaldehyde Emissions Composite wood, TSCA Title VI Small Entity Compliance Guide OPPT NPCD 48
Frequent Questions about EPA's Mercury Inventory Reporting Rule 2019-03-15 2020-02-28 EPA 705-G-2020-2407 Mercury inventory reporting Assistance for reporters on Mercury Inventory Reporting OPPT NPCD 2407
Frequently Asked Questions for Consumers - Formaldehyde Emission Standards for Composite Wood Products 2019-02-08 2020-02-28 EPA 705-G-2020-2196 TSCA Title VI, Composite wood products, formaldehyde Frequently Asked Questions on the TSCA Title VI program from consumers - updated as needed. OPPT NPCD 2196
Frequently Asked Questions for Consumers - Formaldehyde Emission Standards for Composite Wood Products 2019-02-08 2020-02-28 EPA 705-G-2020-2295 TSCA Title VI, Composite wood products, formaldehyde Frequently Asked Questions on the TSCA Title VI program from consumers - updated as needed. OPPT NPCD 2295
Frequently Asked Questions for Regulated Stakeholders - Formaldehyde Emission Standards for Composite Wood Products 2019-02-12 2020-02-28 EPA 705-G-2020-2197 TSCA Title VI, Composite wood products, formaldehyde Frequently Asked Questions on the TSCA Title VI program from regulated stakeholders - updated as needed. OPPT NPCD 2197
Frequently Asked Questions for Regulated Stakeholders - Formaldehyde Emission Standards for Composite Wood Products 2019-02-12 2020-02-28 EPA 705-G-2020-2296 TSCA Title VI, Composite wood products, formaldehyde Frequently Asked Questions on the TSCA Title VI program from regulated stakeholders - updated as needed. OPPT NPCD 2296
Further clarification of AHERA reaccreditation requirements 1991-08-09 2020-02-28 EPA 705-G-2020-3199 Asbestos Further clarification of AHERA reaccreditation requirements explained in an EPA policy statement issued on July 23, 1990; expresses support for guidance provided to Jeffrey Lee of the University of Utah by Dave Combs in attached letter (un-dated duplicate of 8/14/91 letter); also attached to letters dated 3/8/91 and 1/25/91 OPPT NPCD 3199
Further clarification of conversation in which it was established that the Interim Final MAP does not allow a training provider to combine students from different courses 1994-04-01 2020-02-28 EPA 705-G-2020-3178 Asbestos Further clarification of conversation in which it was established that the Interim Final MAP does not allow a training provider to combine students from different courses (representing different disciplines) for the purpose of attending special training modules on selected topics OPPT NPCD 3178
Further clarification of EPA response to two inquiries regarding the applicability of the MAP/TSCA asbestos inspector accreditation requirement 1994-04-18 2020-02-28 EPA 705-G-2020-3180 Asbestos Further clarification of EPA response to two inquiries regarding the applicability of the MAP/TSCA asbestos inspector accreditation requirement to work consisting of general flooring replacement, including installation over existing resilient floor covering OPPT NPCD 3180
Guidance Memo on the Implementation of AHERA Model Contractor Accreditation Plan 1987-06-22 2020-02-28 EPA 705-G-2020-3241 Asbestos Guidance Memo on the Implementation of AHERA Model Contractor Accreditation Plan OPPT NPCD 3241
Guidance of disposal of cable containing PCBs by Puget Sound Shipyard 1992-05-29 2020-02-28 EPA 705-G-2020-3465 PCBs Guidance of regulatory status of cable containing PCBs by Puget Sound Shipyard.  Ship cable is not oil-filled equipment authorized for use at 761.30(m).  It can only be distributed for disposal. OPPT NPCD 3465
Guidelines for Asbestos NESHAP Demolition and Renovation Inspection Procedures 1990-11-01 2020-02-28 EPA 705-G-2020-2712 Asbestos; NESHAP; building demolition and renovation Guidelines for asbestos National Emission Standards for Hazardous Air Pollutants demolition and renovation Inspection procedures. OPPT NPCD 2712
Guidelines for Catastrophic Emergency Situations Involving Asbestos 1992-02-01 2020-02-28 EPA 705-G-2020-2730 Asbestos; emergency response Guidelines for emergency situations involving asbestos. OPPT NPCD 2730
Guidelines for Conducting the AHERA TEM Clearance Test to Determine Completion of an Asbestos Abatement Project - A96 1989-05-01 2020-02-28 EPA 705-G-2020-2767 Asbestos; AHERA Guidelines for Conducting the AHERA TEM Clearance Test to Determine Completion of an Asbestos Abatement Project - A96. OPPT NPCD 2767
Guidelines for Enhanced Management of Asbestos in Water at Ordered Demolitions 2016-07-13 2020-02-28 EPA 705-G-2020-1567 Asbestos Guidelines for Enhanced Management of Asbestos in Water at Ordered Demolitions. OPPT NPCD 1567
Guidelines for reporting test results of HDD and HDF Determinations in Commercial Products 1990-06-01 2020-02-28 EPA 705-G-2020-2201 Part 766, dioxin, furan Guidance for regulated entities to use in reporting test results to the Agency under the 40 CFR 766 regulation.  OPPT NPCD 2201
Guidelines for reporting test results of HDD and HDF Determinations in Commercial Products 1990-06-01 2020-02-28 EPA 705-G-2020-2301 test rule, dioxin, furan, Part 766 Guidance for regulated entities to use in reporting test results to the Agency under the 40 CFR 766 regulation.  OPPT NPCD 2301
Guidelines for the determination of halogenated dibenzo-o-dioxins and dibenzofurans in commercial product 1987-06-19 2020-02-28 EPA 705-G-2020-2200 Dioxin/Furans Guidance for regulated entities to use in developing their analytical testing protocols for submittal to the Agency under the 40 CFR 766 regulation.  OPPT NPCD 2200
Guidelines for the determination of halogenated dibenzo-o-dioxins and dibenzofurans in commercial product 1987-06-19 2020-02-28 EPA 705-G-2020-2300 Part 766, dioxin, furan, test rule Guidance for regulated entities to use in developing their analytical testing protocols for submittal to the Agency under the 40 CFR 766 regulation.  OPPT NPCD 2300
Guidelines for the Review of Test Plans Submitted for the Determination of HDDs and HDFs in Commercial Products 1986-04-24 2020-02-28 EPA 705-G-2020-2202 Dioxin, furan, test rule, Part 766 Agency guidance for the review and determination of analytical testing protocols submitted to the Agency under the 40 CFR 766 regulation.  OPPT NPCD 2202
Guidelines for the Review of Test Plans Submitted for the Determination of HDDs and HDFs in Commercial Products 1986-04-24 2020-02-28 EPA 705-G-2020-2302 Test rule, dioxin, furan, Part 766 Agency guidance for the review and determination of analytical testing protocols submitted to the Agency under the 40 CFR 766 regulation.  OPPT NPCD 2302
Horticultural Vermiculite Fact Sheet- 2000 2000-07-01 2020-02-28 EPA 705-G-2020-3162 Asbestos Horticultural Vermiculite Fact Sheet- 2000 OPPT NPCD 3162
How to Develop and Maintain a Building Asbestos Operations and Maintenance (O&M) Program 2016-12-20 2020-02-28 EPA 705-G-2020-2204 Asbestos Information on how to develop and maintain a building asbestos operations and maintenance (O&M) program OPPT NPCD 2204
How to Manage Asbestos in School Buildings: The AHERA Designated Person's Self Study Guide 2013-03-05 2020-02-28 EPA 705-G-2020-1237 Asbestos This EPA document is designed to assist Asbestos Hazard Emergency Response Act (AHERA) designated persons in understanding their responsibilities to help local education agencies comply with federal asbestos in schools regulations. OPPT NPCD 1237
HTS Codes Related to Composite Wood Products 2019-03-01 2020-02-28 EPA 705-G-2020-2195 HTS codes, TSCA Title VI, formaldehyde, composite wood products, Section 13 Probable Harmonized Tariff Schedule codes that may require a Section 13 import certification under the TSCA Title VI program.  OPPT NPCD 2195
Import of Metals contaminated With PCBs 2000-09-06 2020-02-28 EPA 705-G-2020-3498 PCBs EPA guidance on equivalence of wipe samples to the <2ppm PCB limit for importation. OPPT NPCD 3498
Import of Transformers for reuse 1993-08-11 2020-02-28 EPA 705-G-2020-3473 PCBs EPA guidance on the import of transformers <50 ppm for reuse and status of internal components under the import ban. OPPT NPCD 3473
Individual Lead Abatement Certification Fee and Refund Information 2008-01-01 2020-02-28 EPA 705-G-2020-1482 Lead Fee schedule and refund policy for EPA certification program for individuals performing lead-based paint activities. OPPT NPCD 1482
Information for Owners and Managers of Buildings that Contain Asbestos 2013-03-05 2020-02-28 EPA 705-G-2020-0449 Asbestos Federal requirements for the renovation and demolition of buildings and guidance on developing and maintaining an operations and maintenance program to manage asbestos-containing materials in buildings. OPPT NPCD 449
Inquiry Regarding Electromechanical Impedance Relays 2000-06-21 2020-02-28 EPA 705-G-2020-3485 PCBs Guidance on the regulatory status of Electromechanical Impedance Relays that contain a PCB capacitor. OPPT NPCD 3485
Instructions for Accredited Training Providers 2008-01-01 2020-02-28 EPA 705-G-2020-2331 Lead This page provides instructions for training providers accredited by EPA to teach renovator and dust sampling technician courses in accordance with the Renovation, Repair and Painting Regulation. OPPT NPCD 2331
Instructions for Training Programs Applying for Accreditation of Lead-Based Paint Courses 2008-01-01 2020-02-28 EPA 705-G-2020-1500 Lead Instructions for trainers applying for accreditation of lead activities courses. OPPT NPCD 1500
Instructor Manual - EPA/HUD Model Refresher Lead Dust Sampling Technician Course 2013-06-01 2020-02-28 EPA 740-R-13-001 Lead EPA/HUD Model Refresher Lead Dust Sampling Technician Course - Instructor Manual. OPPT NPCD 2327
Instructor Manual - LEAD Safety for Renovation, Repair, and Painting Model Certified Renovator Initial Training Course, EPA-740-R-09-001 2011-10-01 2020-02-28 EPA 705-G-2020-0711 Lead EPA RRP initial 8-hour renovation training course, instructor manual. OPPT NPCD 711
Intent to ship a PCB sample off-site  2011-10-15 2020-02-28 EPA 705-G-2020-3505 PCBs EPA guidance that PCB waste samples may be shipped domestically without an exemption under 761.80. OPPT NPCD 3505
Interpretation of EPA's regulations concerning the use of large PCB capacitors in restricted access areas 1985-08-28 2020-02-28 EPA 705-G-2020-3408 PCBs Interpretation of EPA's regulations concerning the use of large PCB capacitors in restricted access areas: natural barriers that restrict public access satisfy the regulatory requirement. OPPT NPCD 3408
Interpretation of the PCB regulations regarding management of wastes and products derived from an excluded manufacturing process 1998-03-05 2020-02-28 EPA 705-G-2020-3489 PCBs EPA guidance on the excluded manufacturing process reporting and waste provisions. OPPT NPCD 3489
Interpretive Guidance for the Real Estate Community on the Requirements for Disclosure of Information Concerning Lead-Based Paint in Housing, Part I  1996-08-20 2020-02-28 EPA 705-G-2020-0022 Lead Guidance on rule requiring persons selling or leasing most residential housing built before 1978 to provide purchasers and renters with a federally approved lead hazard information pamphlet (Part 1). OPPT NPCD 22
Interpretive Guidance for the Real Estate Community on the Requirements for Disclosure of Information Concerning Lead-Based Paint in Housing, Part II  1996-12-05 2020-02-28 EPA 705-G-2020-0023 Lead Guidance on rule requiring persons selling or leasing most residential housing built before 1978 to provide purchasers and renters with a federally approved lead hazard information pamphlet (Part 2). OPPT NPCD 23
Interpretive Guidance for the Real Estate Community on the Requirements for Disclosure of Information Concerning Lead-Based Paint in Housing, Part III  2000-08-02 2020-02-28 EPA 705-G-2020-0024 Lead Guidance on rule requiring persons selling or leasing most residential housing built before 1978 to provide purchasers and renters with a federally approved lead hazard information pamphlet (Part 3). OPPT NPCD 24
Interpretive guidance from EPA concerning marking of vehicles that transport PCBs 1983-01-21 2020-02-28 EPA 705-G-2020-3398 PCBs Interpretive guidance from EPA concluding that forklifts are not transport vehicles for purposes of the PCB marking requirements. OPPT NPCD 3398
Interpretive Statement on Change in Ownership of Real Property Contaminated with PCBs August 14, 2003 2003-08-14 2020-02-28 EPA 705-G-2020-2311 PCBs Memorandum from R.E.Fabricant, EPA General Counsel. August 14, 2003.  Interpretive Statement on Change in Ownership of Real Property Contaminated with PCBs: not prohibited distribution in commerce under TSCA PCB regulations. OPPT NPCD 2311
Job-Site Controls for Work Involving Asbestos-Containing Material (ACM) 2016-12-22 2020-02-28 EPA 705-G-2020-2210 Asbestos Guidance on job-site controls for work involving asbestos-containing material (ACM). OPPT NPCD 2210
Laws regarding export of transformers 1991-10-08 2020-02-28 EPA 705-G-2020-3462 PCBs Guidance regarding the export of >50 ppm PCB transformers for reuse and the application of "totally enclosed" to faulty equipment to be re-conditioned. Export for reuse vs export for disposal criteria. OPPT NPCD 3462
Lead Policy and Guidance 2000-01-01 2020-02-28 EPA 705-G-2020-0409 Lead This page describes policy and guidance related to EPA's regulation of lead in paint, dust and soil, lead in water, lead in air, and lead waste disposal. OPPT NPCD 409
LEAD Safety for Renovation, Repair, and Painting Model Certified Renovator Refresher Training Course, Instructor Manual, EPA-740-R-09-003 2011-10-01 2020-02-28 EPA 740-R-09-003 Lead This course was developed by the U.S Environmental Protection Agency in collaboration with HUD to refresh the training of renovation, repair, and painting contractors. OPPT NPCD 2322
Letter to Representative Peter DeFazio clarifying why EPA no longer accredits MAP courses 2012-01-01 2020-02-28 EPA 705-G-2020-3149 Asbestos Letter to Representative Peter DeFazio clarifying why EPA no longer accredits MAP courses OPPT NPCD 3149
Manufacturer Requests for Risk Evaluation, Information for Submitters 2020-02-28 2020-02-28 EPA 705-G-2020-2333 Manufacturer requests, risk evaluation, TSCA Purpose is to provide information/guidance to manufacturers considering submitting a manufacturer request for risk evaluation to the agency. OPPT NPCD 2333
Mercury Electronic Reporting (MER) Application User Guide (3) 2019-03-15 2020-02-28 EPA 705-G-2020-2185 Mercury inventory reporting; elemental mercury; mercury compounds Instructions on how to report information on mercury to EPA Mercury Inventory Reporting. OPPT NPCD 2185
Model AHERA Asbestos Management Plan for Local Education Agencies 2013-03-05 2020-02-28 EPA 705-G-2020-0440 Asbestos Includes General Information Forms, Inspection and Reinspection Forms, Response Action Forms, Operations and Maintenance Forms, Periodic Surveillance Form, and Notification Form. OPPT NPCD 440
Model Certified Lead Dust Sampling Technician Training Course: Instructor Manual, EPA-740-R-09-006 2009-05-01 2020-02-28 EPA 740-R-09-006 Lead Provides the instructor's manual for a course developed by EPA to teach individuals how to conduct non-abatement lead dust clearance testing. OPPT NPCD 2325
Model Certified Lead Dust Sampling Technician Training Course: Student Manual, EPA-740-R-09-005 2009-05-01 2020-02-28 EPA 740-R-09-005 Lead Provides the student manual for a course developed by EPA to teach individuals how to conduct non-abatement lead dust clearance testing. OPPT NPCD 2326
Model Renovation, Repair and Painting (RRP) Rule E-Learning Course Component Implementation Requirements 2011-01-01 2020-02-28 EPA 705-G-2020-2330 Lead This document describes the requirements for e-learning courses. Your application must include a discussion of how you will comply with each requirement listed in this document. OPPT NPCD 2330
Modelo AHERA para el plan de manejo de asbestos para las Angencias locales de educacion 2013-03-05 2020-02-28 EPA 705-G-2020-0443 Asbestos Asbesto en las Escuelas--Spanish asbestos guidance on AHERA. OPPT NPCD 443
Monitoring Asbestos-Containing Material (ACM) 2016-12-20 2020-02-28 EPA 705-G-2020-2209 Asbestos Guidance on how to test and monitor asbestos-containing materials (ACM) in buildings.  OPPT NPCD 2209
National Lead Laboratory Accreditation Program - Memorandum of Agreement on Collaboration between the Office of Pollution Prevention and Toxics of the U.S. Environmental Protection Agency and the [Organization's Name]. 2000-01-01 2020-02-28 EPA 705-G-2020-0390 Lead The purpose of this Memorandum of Understanding between the OPPT and [Organization's Name] is to recognize [ORGANIZATION'S NAME] as a laboratory accrediting organization. OPPT NPCD 390
National Lead Laboratory Accreditation Program: Laboratory Quality System Requirements 2007-07-05 2020-02-28 EPA 705-G-2020-2320 Lead This document identifies the minimum requirements for use by accreditation organizations when evaluating laboratories performing environmental testing activities. OPPT NPCD 2320
Occupant Notification in Buildings Containing Asbestos 2016-12-20 2020-02-28 EPA 705-G-2020-2208 Asbestos How to notify building occupants about asbestos. OPPT NPCD 2208
Paint Chip Sample Collection Guide Lead Renovation, Repair and Painting Program 2011-10-01 2020-02-28 EPA 705-G-2020-2319 Lead Provides step by step instruction in how to collect paint chip samples and submit them for analysis. OPPT NPCD 2319
PCB Inspection Manual 2004-08-01 2020-02-28 EPA 705-G-2020-2315 PCBs Guidance for PCB inspections under TSCA. Compliance guidance. OPPT NPCD 2315
PCB large capacitors phase-out requirements 1989-01-10 2020-02-28 EPA 705-G-2020-3445 PCBs EPA's interpretation of the scope of the PCB large capacitor phase-out requirements. Restricted access does not refer to a capacitor specific location within a building with general restricted public access. OPPT NPCD 3445
PCB transformer ownership 1986-01-21 2020-02-28 EPA 705-G-2020-3416 PCBs Guidance on PCB transformer ownership for condominium units. OPPT NPCD 3416
PCBs in Building Materials—Questions & Answers July 28, 2015 2015-07-28 2020-02-28 EPA 705-G-2020-2306 PCBs EPA guidance on managing PCBs in caulk and other building materials. OPPT NPCD 2306
Pink Book: Asbestos in Buildings: Simplified Sampling Scheme for Friable Surfacing Materials 1985-10-01 2020-02-28 EPA 705-G-2020-2763 Asbestos Pink Book: Asbestos in Buildings: Simplified Sampling Scheme for Friable Surfacing Materials OPPT NPCD 2763
Plan de manejo de asbestos de AHERA 2013-03-05 2020-02-28 EPA 705-G-2020-0437 Asbestos Asbesto en las Escuelas; How to do an asbestos management plan under AHERA. OPPT NPCD 437
Planning for Polychlorinated Biphenyl (PCB)-Containing Disaster Debris June 2011 2011-06-01 2020-02-28 EPA 705-G-2020-2312 PCBs Guidance for managing PCBs after a natural disaster OPPT NPCD 2312
Policy Clarification for the Asbestos Hazard Emergency Response Act  (AHERA) 7/92 1992-07-01 2020-02-28 EPA 705-G-2020-2761 Asbestos; AHERA Policy Clarification for the Asbestos Hazard Emergency Response Act  (AHERA) 7/92 OPPT NPCD 2761
Policy guidance addressing ten AHERA accreditation issues that have been reviewed by EPA Headquarters in consultation with the EPA Regional Offices 1990-04-18 2020-02-28 EPA 705-G-2020-3223 Asbestos Policy guidance addressing ten AHERA accreditation issues that have been reviewed by EPA Headquarters in consultation with the EPA Regional Offices OPPT NPCD 3223
Polychlorinated Biphenyl (PCB) Site Revitalization Guidance Under the Toxic Substances Control Act (TSCA) 2005-11-01 2020-02-28 EPA 705-G-2020-0026 PCBs Guidance for complying with the TSCA regulations for the cleanup and disposal of PCB contamination, including Brownfield sites. OPPT NPCD 26
Polychlorinated Biphenyls (PCBs) Penalty Policy April 9, 1990 1990-04-09 2020-02-28 EPA 705-G-2020-2313 PCBs EPA guidance on penalty calculation for violations of TSCA PCB regulations. OPPT NPCD 2313
Polychlorinated Biphenyls (PCBs) Question and Answer Manual: June 2014 Version 2014-06-01 2020-02-28 EPA 705-G-2020-2303 PCBs Revisions to the PCB Q and A Manual, June 2014 version OPPT NPCD 2303
Post-Disaster Renovations and Lead-Based Paint 2009-01-01 2020-02-28 EPA 705-G-2020-2332 Lead This explains the emergency provision of the RRP Rule in detail and provide guidance on how it applies during the immediate response to a natural disaster. OPPT NPCD 2332
Practical Actions for Reducing Exposure to PCBs in Schools and Other Buildings July 28, 2015 2015-07-28 2020-02-28 EPA 705-G-2020-2307 PCBs Guidance for school administrators and other building owners and managers OPPT NPCD 2307
Protect Your Family from Asbestos-Contaminated Vermiculite Insulation 2013-03-05 2020-02-28 EPA 705-G-2020-0447 Asbestos What to do if you suspect that you might have vermiculite insulation from Libby, Montana. OPPT NPCD 447
Protect Your Family from Exposures to Asbestos 2013-03-05 2020-02-28 EPA 705-G-2020-0445 Asbestos Families can find information on possible means of exposure to asbestos in their homes and cars. This portal also offers insight in how to prevent asbestos exposure. OPPT NPCD 445
Protect Your Family from Lead in Your Home 2020-01-01 2020-02-28 EPA 747-K-12-001 Lead General information about lead-based paint. Required to be provided to prospective buyers and renters of pre-1978 homes and apartments. OPPT NPCD 2317
Protocol for Conducting Environmental Compliance Audits of Facilities with PCBs, Asbestos, and Lead-based Paint Regulated under TSCA 2000-03-01 2020-02-28 EPA 705-G-2020-2728 Asbestos; TSCA Protocol for conducting environmental compliance audits of facilities with PCBs, asbestos, and lead-based paint regulated under TSCA OPPT NPCD 2728
Purple Book: Guidance for Controlling Friable Asbestos-Containing Materials in Buildings 1985-06-01 2020-02-28 EPA 705-G-2020-2762 Asbestos Purple Book: Guidance for Controlling Friable Asbestos-Containing Materials in Buildings  OPPT NPCD 2762
Questions about PCBs in x-ray tube heads and transformers and governing equipment 1984-11-07 2020-02-28 EPA 705-G-2020-3405 PCBs EPA guidance on application of PCB regulations to PCBs in x-ray tube heads and transformers and governing equipment in medical health diagnostic equipment,  Response to FDA inquiry. OPPT NPCD 3405
Questions and Answers on the Mercury Export Ban Act (MEBA 2008) 2010-06-02 2020-02-28 EPA 705-G-2020-2183 Export ban, elemental mercury  24 questions and answers on prohibition on exporting elemental mercury OPPT NPCD 2183
Questions and Answers on the Mercury Export Ban Act (MEBA 2008) 2010-06-02 2020-02-28 EPA 705-G-2020-2404 Elemental mercury export ban 24 questions and answers on prohibition on exporting elemental mercury OPPT NPCD 2404
Questions and Answers Regarding Laminate Flooring 2015-01-01 2020-02-28 EPA 705-G-2020-1249 Formaldehyde This document provides questions and answers prepared to address formaldehyde concerns related to laminate flooring. OPPT NPCD 1249
Recommended interim guidelines for stripping wax or finish coat from asbestos-containing floors 1990-07-01 2020-02-28 EPA 705-G-2020-3212 Asbestos Recommended interim guidelines for stripping wax or finish coat from asbestos-containing floors OPPT NPCD 3212
Recordkeeping for Asbestos Operation and Management (O&M) Plans 2016-12-20 2020-02-28 EPA 705-G-2020-2212 Asbestos Information on the type of records to keep as part of a building asbestos O&M plan. OPPT NPCD 2212
Refresher Student Manual - LEAD Safety for Renovation, Repair, and Painting Model Certified Renovator Training Course, EPA-740-R-09-004 2011-10-01 2020-02-28 EPA 705-G-2020-0724 Lead PDF copy of the RRP refresher training student manual OPPT NPCD 724
Regulatory status of certain cables containing PCBs that are present on two tug boats to be donated t Seattle Maritime 2008-12-11 2020-02-28 EPA 705-G-2020-3503 PCBs EPA guidance to MARAD on the PCB regulatory status of sheathed, non-liquid cables used on ships. OPPT NPCD 3503
Regulatory status of electrical insulating compound, epoxy, used in small electrical equipment 2001-11-27 2020-02-28 EPA 705-G-2020-3487 PCBs Guidance on the PCB regulatory status of non-liquid epoxy electrical insulating compounds used in small electrical equipment including Current and Potential transformers. OPPT NPCD 3487
Regulatory status of the electrical insulator, butyl rubber, used in smaller electrical equipment 2001-04-03 2020-02-28 EPA 705-G-2020-3499 PCBs EPA guidance on the PCB regulatory status of the electrical insulator, butyl rubber, used in smaller electrical equipment such as current or potential transformers. OPPT NPCD 3499
Regulatory Status of Waste Generated by Contractors and Residents from Lead-Based Paint Activities Conducted in Households (August 2000) 2000-08-01 2020-02-28 EPA 705-G-2020-0399 Lead Clarifications for how contractors can handle lead-based paint waste during residential renovations. OPPT NPCD 399
Renovate Right: Important Lead Hazard Information for Families, Child Care Providers, and Schools 2011-09-01 2020-02-28 EPA 740-K-10-001 Lead General information about legal requirements for safe lead practices for homeowners, tenants, child care providers and parents during renovation activities. OPPT NPCD 2316
Reporting and Recordkeeping Requirements for Waste Disposal; A Field Guide 1990-11-01 2020-02-28 EPA 705-G-2020-2719 Asbestos; disposal Guide for reporting and recordkeeping requirements for disposal of waste containing asbestos OPPT NPCD 2719
Request clarification of the status of bushings associated with oil filled circuit 1995-08-29 2020-02-28 EPA 705-G-2020-3479 PCBs EPA guidance on bushings attached to transformers also applies to other electrical equipment, including circuit breakers and voltage regulators under 761.30(h) & (m). OPPT NPCD 3479
Request for clarification as to whether an in-house training program qualifies as an EPA-accredited training course 1993-03-03 2020-02-28 EPA 705-G-2020-3188 Asbestos Request for clarification as to whether an in-house training program qualifies as an EPA-accredited training course and whether an Asbestos Program Manager must take the California State Asbestos Consultant Certification Examination; attached to letter dated 3/3/93 OPPT NPCD 3188
Request for Clarification of Conflict of Interest Issues - Responsibility for Conflict of Interest Provisions Concerning Air Cleaners Under AHERA 1990-05-18 2020-02-28 EPA 705-G-2020-3220 Asbestos Request for Clarification of Conflict of Interest Issues - Responsibility for Conflict of Interest Provisions Concerning Air Cleaners Under AHERA OPPT NPCD 3220
Request for clarification of the terms commercial building and industrial building as they appear in the PCB transformer fires final rule 1985-09-23 2020-02-28 EPA 705-G-2020-3412 PCBs EPA clarification of the terms commercial building and industrial building as they appear in the PCB transformer fires final rule. Dual purpose buildings and commercial buildings on industrial sites, including chemical plants. OPPT NPCD 3412
Request for clarification on two issues 1994-07-19 2020-02-28 EPA 705-G-2020-3175 Asbestos Request for clarification on two issues: whether persons collecting asbestos bulk samples on an infrequent or occasional basis are subject to MAP inspector accreditation requirements, and whether accredited workers and/or contractor/supervisors may perform this function without obtaining separate inspector accreditation OPPT NPCD 3175
Request for EPA clarification of the definition of "excluded manufacturing process" 1998-03-24 2020-02-28 EPA 705-G-2020-3490 PCBs Guidance on the "excluded manufacturing process" status of imported dielectric fluid contaminated during storage and transport. OPPT NPCD 3490
Request for Guidance on the Disposal of Cable Containing PCBs by Puget Sound Naval Shipyard 1992-05-29 2020-02-28 EPA 705-G-2020-3393 PCBs EPA Guidance on the Disposal of Cable Containing PCBs found in ships.  Ship cable is neither "totally enclosed" nor authorized for use or distribution in commerce for purposes other than disposal. OPPT NPCD 3393
Request for information regarding the proper procedures for disposal of a transformer 1987-09-16 2020-02-28 EPA 705-G-2020-3432 PCBs Procedures for rentry and disposal of a transformer belonging to VoA under EPA returns policy for USG's PCBs. OPPT NPCD 3432
Request for interpretation of the Asbestos Hazard Emergency Response Act (AHERA), 40 CFR 763, regarding AHERA-credited employees of Corpus Christi Independent School District performing both asbestos abatement and air monitoring tasks 1989-01-06 2020-02-28 EPA 705-G-2020-3231 Asbestos Request for interpretation of the Asbestos Hazard Emergency Response Act (AHERA), 40 CFR 763, regarding AHERA-credited employees of Corpus Christi Independent School District performing both asbestos abatement and air monitoring tasks OPPT NPCD 3231
Request for official EPA interpretation of ASHARA requirements 1993-07-12 2020-02-28 EPA 705-G-2020-3186 Asbestos Request for official EPA interpretation of ASHARA requirements as they apply to Idaho safety advisors who look for potential ACM during safety inspections but do not collect samples or make recommendations on how to handle the materials if asbestos is present; attached to letters dated 7/12/93, 6/21/93, and 5/27/93 OPPT NPCD 3186
Request to return PCBs in Antarctica to the United States for disposal 1994-03-11 2020-02-28 EPA 705-G-2020-3475 PCBs Guidance on EPA policy on return of USG PCBs from overseas installations. OPPT NPCD 3475
Requesting EPA assistance in returning hazardous waste shipments that was stranded in Canada 2000-07-31 2020-02-28 EPA 705-G-2020-3394 PCBs Policy statement to Government of Canada that PCB shipments to Canada may be returned without violation of the TSCA PCB import ban, subject to attached procedures. OPPT NPCD 3394
Response letter to the request to have stay four provisions of the PCB Disposal Amendments published 1998-09-02 2020-02-28 EPA 705-G-2020-3397 PCBs EPA clarification of the storage for reuse provisions in the 1998 PCB Disposal Amendments to all facilities. OPPT NPCD 3397
Response regarding 1999 PCB Questions and Answer manual 1999-01-01 2020-02-28 EPA 705-G-2020-3496 PCBs Supplemental guidance to the PCB Questions and EPA Answers manual. OPPT NPCD 3496
Response to 1/8/91 inquiry regarding the sale and transfer of AHERA training accreditation and the potential for conflict-of-interest when a firm trains its own workers 1991-01-16 2020-02-28 EPA 705-G-2020-3203 Asbestos Response to 1/8/91 inquiry regarding the sale and transfer of AHERA training accreditation and the potential for conflict-of-interest when a firm trains its own workers OPPT NPCD 3203
Response to 12/21/94 inquiry regarding the applicability of Asbestos MAP training requirements to persons who conduct the asbestos portion of environmental assessments 1995-01-03 2020-02-28 EPA 705-G-2020-3172 Asbestos Response to 12/21/94 inquiry regarding the applicability of Asbestos MAP training requirements to persons who conduct the asbestos portion of environmental assessments OPPT NPCD 3172
Response to 6/2/93 memo explaining the circumstances surrounding John V. Savio’s request to use EPA’s AHERA training course approval given to “Retra Services, Inc. 1993-06-08 2020-02-28 EPA 705-G-2020-3187 Asbestos Response to 6/2/93 memo explaining the circumstances surrounding John V. Savio’s request to use EPA’s AHERA training course approval given to “Retra Services, Inc.” for his new training firm: “Retra Training Services, Inc.”; observes that granting such a request would violate EPA policy; attached to letter dated 6/2/93 and to undated letter from John Savio OPPT NPCD 3187
Response to Comments Document on the Proposed Rule -- Disposal of Polychlorinated Biphenyls (PCBs) OPPTS Docket #66009A May 1998 1998-05-01 2020-02-28 EPA 705-G-2020-2305 PCBs EPAs response to comments on the 1994 proposed PCB disposal amendments rule. OPPT NPCD 2305
Response to correspondence that National Fuel Gas Distribution Corporation sent to the EPA requesting an alternative sampling location 2006-09-18 2020-02-28 EPA 705-G-2020-3502 PCBs EPA determination that orifice plates do not provide a suitable alternative sampling location for purposes of compliance with the PCB natural gas pipeline use authorization. OPPT NPCD 3502
Response to inquiry about AHERA’s applicability to certain types of facilities and the existence of assistance programs to aid minority schools in complying with AHERA 1988-07-15 2020-02-28 EPA 705-G-2020-3236 Asbestos Response to inquiry about AHERA’s applicability to certain types of facilities and the existence of assistance programs to aid minority schools in complying with AHERA OPPT NPCD 3236
Response to inquiry about the limitations imposed by AHERA on the types of clean-up work that can be performed by an O&M worker with 16 hours of training 2005-05-05 2020-02-28 EPA 705-G-2020-3158 Asbestos Response to inquiry about the limitations imposed by AHERA on the types of clean-up work that can be performed by an O&M worker with 16 hours of training OPPT NPCD 3158
Response to inquiry about whether accreditation requirements apply to persons removing nonfriable ACM from schools and public and commercial buildings 1993-01-13 2020-02-28 EPA 705-G-2020-3189 Asbestos Response to inquiry about whether accreditation requirements apply to persons removing nonfriable ACM from schools and public and commercial buildings OPPT NPCD 3189
Response to inquiry about whether it is permissible to maintain records pertaining to the asbestos in schools rule under the Asbestos Hazard Emergency Response Act (AHERA) in electronic format 2005-11-01 2020-02-28 EPA 705-G-2020-3157 Asbestos Response to inquiry about whether it is permissible to maintain records pertaining to the asbestos in schools rule under the Asbestos Hazard Emergency Response Act (AHERA) in electronic format OPPT NPCD 3157
Response to inquiry from ATC Associates Inc. regarding AHERA regulations concerning vermiculite insulation testing in schools and the treatment of vermiculite insulation as non-asbestos containing materials if found negative for asbestos using PLM 2009-03-01 2020-02-28 EPA 705-G-2020-3151 Asbestos Response to inquiry from ATC Associates Inc. regarding AHERA regulations concerning vermiculite insulation testing in schools and the treatment of vermiculite insulation as non-asbestos containing materials if found negative for asbestos using PLM OPPT NPCD 3151
Response to inquiry on whether the EPA MAP prohibits EPA MAP approved states from approving training providers to teach online refresher training 2006-04-06 2020-02-28 EPA 705-G-2020-3155 Asbestos Response to inquiry on whether the EPA MAP prohibits EPA MAP approved states from approving training providers to teach online refresher training OPPT NPCD 3155
Response to inquiry regarding air transfer system employed by Minteq International Inc. 2000-08-17 2020-02-28 EPA 705-G-2020-3486 PCBs Guidance regarding the applicability of the 761.30(t) authorization to vacuum pump systems, leaking systems and systems in use prior to June 29, 1998. OPPT NPCD 3486
Response to inquiry regarding EPA's PCB Disposal Amendments 1999-11-17 2020-02-28 EPA 705-G-2020-3400 PCBs EPAs general guidance on the applicability of  761.50(b)(3) to post-April 1978 wastes at as found concentrations less than 50 ppm. OPPT NPCD 3400
Response to inquiry regarding the applicability of Federal asbestos inspector accreditation requirements to real estate appraisers; concurrence pages attached; letter dated 8/16/95 and “Master Appraiser” issue faxed on 7/1/95 also attached 1995-12-08 2020-02-28 EPA 705-G-2020-3170 Asbestos Response to inquiry regarding the applicability of Federal asbestos inspector accreditation requirements to real estate appraisers; concurrence pages attached; letter dated 8/16/95 and “Master Appraiser” issue faxed on 7/1/95 also attached OPPT NPCD 3170
Response to inquiry regarding the responsibilities of an AHERA project designer based on the requirements set forth in the Revised MAP, which was published on February 3, 1994 1994-03-16 2020-02-28 EPA 705-G-2020-3182 Asbestos Response to inquiry regarding the responsibilities of an AHERA project designer based on the requirements set forth in the Revised MAP, which was published on February 3, 1994 OPPT NPCD 3182
Response to Letter Regarding Export of Untested Distribution of Transformers 1994-04-15 2020-02-28 EPA 705-G-2020-3477 PCBs EPA guidance on prohibition of export of untested distribution of transformers assumed to be PCB-contaminated, and on export for scrap/salvage. OPPT NPCD 3477
Response to request for EPA confirmation that addressee’s firm is qualified to provide asbestos training in foreign languages 1990-06-05 2020-02-28 EPA 705-G-2020-3218 Asbestos Response to request for EPA confirmation that addressee’s firm is qualified to provide asbestos training in foreign languages to employees and contractors of the U.S. Defense Department in Europe; clarifies that non-worker courses must be provided in English for accreditation OPPT NPCD 3218
Response to request for interpretation of PCB regulations referring to the use of asphalt pavement 1990-09-27 2020-02-28 EPA 705-G-2020-3457 PCBs Response to request for interpretation of PCB regulations referring to the use of asphalt pavement, contaminated during processing by used oil containing <50 ppm PCB excluded PCB product. OPPT NPCD 3457
Response to request for permission to export used ballasts with PCB capacitors for resale and reuse purposes 1997-07-16 2020-02-28 EPA 705-G-2020-3481 PCBs Guidance on the export of used light ballasts (FLBs) with PCB small capacitors for resale and reuse purposes. OPPT NPCD 3481
Response to the EPA's interpretation of the scope of the PCB large capacitor phase-out requirements 1988-11-02 2020-02-28 EPA 705-G-2020-3440 PCBs Response to the EPA's interpretation of the scope of the PCB large capacitor phase-out requirements. Restricted access does not refer to a capacitors location within a building. OPPT NPCD 3440
Rules and Regulations Regarding the Demolition of Asbestos-Containing Structures 2013-03-05 2020-02-28 EPA 705-G-2020-0436 Asbestos Rules and regulations pursuant to the asbestos NESHAP for demolitions of asbestos-containing structures. OPPT NPCD 436
Safe Work Practices 2016-11-14 2020-02-28 EPA 705-G-2020-2211 Asbestos This page describes the types of safe work  asbestos work practices and when they should be applied OPPT NPCD 2211
Sale of National Defense Reserves Fleet ships for foreign disposal and recycling of vessels' materials 1994-07-08 2020-02-28 EPA 705-G-2020-3478 PCBs Guidance on Sale of National Defense Reserves Fleet ships for foreign disposal and recycling of vessels' materials; status of ships containing PCBs leased to a foreign country. OPPT NPCD 3478
Setting up an Asbestos Operations and Maintenance (O&M) Program 2016-12-20 2020-02-28 EPA 705-G-2020-2206 Asbestos How to set up an asbestos operations and maintenance program. OPPT NPCD 2206
Silver Book: Measuring Airborne Asbestos Following An Abatement Action 1985-11-01 2020-02-28 EPA 705-G-2020-2766 Asbestos Silver Book: Measuring Airborne Asbestos Following An Abatement Action OPPT NPCD 2766
Small Entity Compliance for Formaldehyde Standards in Composite Wood Products - Accreditation Bodies 2018-04-01 2020-02-28 EPA 705-G-2020-2186 formaldehyde, TSCA Title VI Webinar Presentation for Accreditation Bodies under the TSCA Title VI program OPPT NPCD 2186
Small Entity Compliance for Formaldehyde Standards in Composite Wood Products - Accreditation Bodies 2018-04-01 2020-02-28 EPA 705-G-2020-2285 TSCA Title VI, Composite wood products, formaldehyde Webinar Presentation for Accreditation Bodies under the TSCA Title VI program OPPT NPCD 2285
Small Entity Compliance for Formaldehyde Standards in Composite Wood Products - Fabricators and Laminated Product Producers  2018-04-01 2020-02-28 EPA 705-G-2020-2190 TSCA Title VI, Composite wood products, formaldehyde Webinar Presentation for Fabricators and Laminated Product Producers under the TSCA Title VI program OPPT NPCD 2190
Small Entity Compliance for Formaldehyde Standards in Composite Wood Products - Fabricators and Laminated Product Producers  2018-04-01 2020-02-28 EPA 705-G-2020-2289 TSCA Title VI, Composite wood products, formaldehyde Webinar Presentation for Fabricators and Laminated Product Producers under the TSCA Title VI program OPPT NPCD 2289
Small Entity Compliance for Formaldehyde Standards in Composite Wood Products - General Audiences  2018-04-01 2020-02-28 EPA 705-G-2020-2187 TSCA Title VI, Composite wood products, formaldehyde Webinar Presentation for a General Audience under the TSCA Title VI program OPPT NPCD 2187
Small Entity Compliance for Formaldehyde Standards in Composite Wood Products - General Audiences  2018-04-01 2020-02-28 EPA 705-G-2020-2286 TSCA Title VI, Composite wood products, formaldehyde Webinar Presentation for a General Audience under the TSCA Title VI program OPPT NPCD 2286
Small Entity Compliance for Formaldehyde Standards in Composite Wood Products - Panel Producers  2018-04-01 2020-02-28 EPA 705-G-2020-2189 TSCA Title VI, Composite wood products, formaldehyde Webinar Presentation for Panel Producers under the TSCA Title VI program OPPT NPCD 2189
Small Entity Compliance for Formaldehyde Standards in Composite Wood Products - Panel Producers  2018-04-01 2020-02-28 EPA 705-G-2020-2288 TSCA Title VI, Composite wood products, formaldehyde Webinar Presentation for Panel Producers under the TSCA Title VI program OPPT NPCD 2288
Small Entity Compliance for Formaldehyde Standards in Composite Wood Products - Third Party Certifiers   2018-04-01 2020-02-28 EPA 705-G-2020-2188 TSCA Title VI, Composite wood products, formaldehyde Webinar Presentation for Third Party Certifiers under the TSCA Title VI program OPPT NPCD 2188
Small Entity Compliance for Formaldehyde Standards in Composite Wood Products - Third Party Certifiers   2018-04-01 2020-02-28 EPA 705-G-2020-2287 TSCA Title VI, Composite wood products, formaldehyde Webinar Presentation for Third Party Certifiers under the TSCA Title VI program OPPT NPCD 2287
Small Entity Compliance for Formaldehyde Standards in Composite Wood Products -Importers, Distributors, and Retailers  2018-04-01 2020-02-28 EPA 705-G-2020-2191 TSCA Title VI, Composite wood products, formaldehyde Webinar Presentation for Importers, Distributors, and Retailers under the TSCA Title VI program OPPT NPCD 2191
Small Entity Compliance for Formaldehyde Standards in Composite Wood Products -Importers, Distributors, and Retailers  2018-04-01 2020-02-28 EPA 705-G-2020-2290 TSCA Title VI, Composite wood products, formaldehyde Webinar Presentation for Importers, Distributors, and Retailers under the TSCA Title VI program OPPT NPCD 2290
Small Entity Compliance Guide for Lead-Based Paint Activities Training and Certification for Renovation and Remodeling Section 402(c)(3) 2011-10-01 2020-02-28 EPA 705-G-2020-0049 Lead-based Paint; Training; Renovation & Remodeling; Small Entity Compliance Guide for the Lead-based Paint Renovation, Repair and Painting regulation. OPPT NPCD 49
Small Entity Compliance Guide for Lead-Based Paint Activities Training, Accreditation, and Certification Rule and Model State Plan Rule--Section 402(a) 2002-07-01 2020-02-28 EPA 705-G-2020-0050 Lead-based Paint; Training Small Entity Compliance Guide for the Lead-based Paint Activities regulation. OPPT NPCD 50
Statement supporting the applicability of the asbestos contractor accreditation requirement under TSCA to federal employees and federal facilities; includes rationale for legal interpretation 1993-08-16 2020-02-28 EPA 705-G-2020-3185 Asbestos Statement supporting the applicability of the asbestos contractor accreditation requirement under TSCA to federal employees and federal facilities; includes rationale for legal interpretation OPPT NPCD 3185
Status of coal tar wrap greater that 50 ppm PCBs on external surfaces of some natural gas piping systems 2006-06-22 2020-02-28 EPA 705-G-2020-3488 PCBs Guidance on regulatory status of coal tar wrap containing >50 ppm PCBs on external surfaces of some natural gas piping systems: use is not authorized by 761.30(i). OPPT NPCD 3488
Status of DuPont as an End User of Natural Gas 1999-07-15 2020-02-28 EPA 705-G-2020-3484 PCBs Guidance on scope of end user provision in PCB natural gas regulations at 761.30(i). OPPT NPCD 3484
Steps to LEAD SAFE Renovation, Repair and Painting 2011-10-01 2020-02-28 EPA 740-K-11-001 Lead Information for contractors and homeowners on how to plan for and complete a home renovation, repair or painting project in pre-1978 housing and child-occupied facilities using lead-safe work practices. OPPT NPCD 2318
Student Manual - EPA/HUD Model Refresher Lead Dust Sampling Technician Course 2013-06-01 2020-02-28 EPA 740-R-13-001 Lead EPA/HUD Model Refresher Lead Dust Sampling Technician Course - Student Manual OPPT NPCD 2328
Student Manual - LEAD Safety for Renovation, Repair, and Painting Model Certified Renovator Initial Training Course, EPA-740-R-09-002 2011-10-01 2020-02-28 EPA 740-R-09-002 Lead This course was developed by the U.S Environmental Protection Agency in collaboration with HUD to train renovation, repair, and painting contractors. OPPT NPCD 2321
Summary of EPA’s final accreditation policy decisions and recommendations 1990-02-06 2020-02-28 EPA 705-G-2020-3225 Asbestos Summary of EPA’s final accreditation policy decisions and recommendations on the following subjects: 1) instructors, 2) duration of courses, 3) auditing contingently approved courses, 4) ideas for site visits and audits, 5) fully approved pre-1987 courses, 6) worker and contractor/supervisor refresher courses, 7) providing refresher-only courses, 8) non-English courses, and 9) retaking examinations; distributed in final form (with one additional subject) to training course providers on 4/18/90 OPPT NPCD 3225
Supplement to earlier accreditation policy guidance, distributed on 4/18/90, that clarifies EPA’s policy regarding single-instructor refresher courses 1990-05-20 2020-02-28 EPA 705-G-2020-3222 Asbestos Supplement to earlier accreditation policy guidance, distributed on 4/18/90, that clarifies EPA’s policy regarding single-instructor refresher courses OPPT NPCD 3222
Technical Guidance for Determining the Presence of Polychlorinated Biphenyls (PCBs) at Regulated Concentrations on Vessels (Ships) to be Reflagged  November 2013 2013-11-01 2020-02-28 EPA 705-G-2020-2314 PCBs Guidance for sampling ships for PCBs OPPT NPCD 2314
The ABCs of Asbestos In Schools 2013-03-05 2020-02-28 EPA 705-G-2020-0438 Asbestos This Environmental Protection Agency (EPA) guidance to helps Local Education Agencies (LEAs) achieve compliance for Asbestos-Containing Materials in Schools regulation (40 CFR Part 763). OPPT NPCD 438
Transmission Electron Microscopy Asbestos Laboratories; Quality Assurance Guidelines 1989-12-01 2020-02-28 EPA 705-G-2020-2721 Asbestos Guidelines for quality assurance in transmission electron microscopy asbestos laboratories OPPT NPCD 2721
TSCA Section 402/404 Lead-Based Paint Renovation Program: 40 CFR Part 745 Subpart E: Residential Property Renovation State, Territorial and Tribal Program Authorization Guidance: December 28, 2017 2017-12-28 2020-02-28 EPA 705-G-2020-0393 Lead Guidance document to assist states, territories, and federally recognized Indian tribes who are seeking authorization of lead-based paint renovation programs. OPPT NPCD 393
TSCA Storage Disposal Requirements for PCB Fluorescent Light Ballasts 2016-08-01 2020-02-28 EPA 705-G-2020-2310 PCBs Guidance for management of PCB light ballasts FLBs OPPT NPCD 2310
Use of PCBs Removed from Capacitors as a laboratory analytical standards 1992-01-30 2020-02-28 EPA 705-G-2020-3463 PCBs EPA guidance that PCB liquid removed from PCB capacitors is regulated for disposal and cannot be re-used to make laboratory analytical standards. OPPT NPCD 3463
User guide to Mercury Electronic Reporting Application 2019-03-15 2020-02-28 EPA 705-G-2020-2406 Mercury inventory reporting; user guide; application; MER User guide to Mercury Electronic Reporting Application OPPT NPCD 2406
What is an Operations and Maintenance (O&M) Program? 2016-12-20 2020-02-28 EPA 705-G-2020-2205 Asbestos Guidance on an operations and maintenance program. OPPT NPCD 2205
What Local Education Agencies (LEAs) should know about the Asbestos National Emission Standard for Air Pollutants (NESHAP) 2013-03-05 2020-02-28 EPA 705-G-2020-0435 Asbestos Overview of regulations covering LEAs that perform renovations or demolitions. OPPT NPCD 435
Whether Floor Tile is Considered ACBM with Varying Results from PLM and TEM 2010-11-03 2020-02-28 EPA 705-G-2020-3150 Asbestos Whether Floor Tile is Considered ACBM with Varying Results from PLM and TEM OPPT NPCD 3150
White Book:  Guide to respiratory Protection for the Asbestos Abatement Industry 1986-09-01 2020-02-28 EPA 705-G-2020-2764 Asbestos White Book: Guide to respiratory Protection for the Asbestos Abatement Industry OPPT NPCD 2764
Asbestos Q&As 1989-12-01 2020-02-28 EPA 705-G-2020-3687 Asbestos Various questions and answers for the public on asbestos in schools and other buildings. OPPT NPCD 3687
Alternative Test Methods and Strategies to Reduce Vertebrate Animal Testing 2017-10-03 2020-02-28 EPA 705-G-2020-1713 Assessing and Managing Chemicals under TSCA EPA's approach on new approach methodologies (NAMs). OPPT RAD 1713
Analog Identification Methodology (AIM) Tool 2012-12-11 2020-02-28 EPA 705-G-2020-3652 TSCA Designed to facilitate a data search on a chemical of interest in addition to identification of potential structural analogs and associated data which can be used to support read across approaches and data gap filling. OPPT RAD 3652
Approaches to Estimate Consumer Exposure under TSCA 2011-01-01 2020-02-28 EPA 705-G-2020-3677 TSCA Introduction to estimating consumer exposures, explanation of available models, and why EPA uses them. OPPT RAD 3677
AQUATOX - Linking water quality and aquatic life 2018-09-01 2020-02-28 EPA 705-G-2020-3665 TSCA AQUATOX predicts the fate of various pollutants, such as nutrients and organic chemicals, and their effects on the ecosystem, including fish, invertebrates, and aquatic plants. This model is a valuable tool for ecologists, biologists, water quality modelers, and anyone involved in performing ecological risk assessments for aquatic ecosystems. OPPT RAD 3665
Arthur D. Little ADL Polymer Migration Estimation Model (AMEM) 2001-06-01 2020-02-28 EPA 705-G-2020-3671 TSCA Documentation within the model provide guidance on how to use the it. OPPT RAD 3671
CEM-Consumer Exposure Model Download and Install Instructions 2015-09-01 2020-02-28 EPA 705-G-2020-3664 TSCA Documentation within the model provide guidance on how to use the it. OPPT RAD 3664
Chemical Assessment Clustering Engine (ChemACE) 2012-06-26 2020-02-28 EPA 705-G-2020-3653 TSCA ChemACE is designed to assist in the review and prioritization of large inventories of chemicals and to facilitate read across and data gap filling for untested substances. OPPT RAD 3653
Chemical Half-Lives for Toxics Release Inventory (TRI) Chemicals 1998-07-30 2020-02-28 EPA 705-G-2020-3684 TSCA Provides the strategy for determining environmental degradation rate constants. OPPT RAD 3684
ChemSTEER-Chemical Screening Tool for Exposures and Environmental Releases 2019-09-30 2020-02-28 EPA 705-G-2020-3658 TSCA Estimates environmental releases and worker exposures resulting from chemical manufacture, processing, and/or use in industrial and commercial workplaces. OPPT RAD 3658
Community Air Screening How-to Manual 2015-09-01 2020-02-28 EPA 705-G-2020-3679 TSCA A Step-by-Step Guide to Using a Risk-Based Approach to Identify Priorities for Improving Outdoor Air Quality OPPT RAD 3679
Considerations When Evaluating Exposure Assessments 2015-09-01 2020-02-28 EPA 705-G-2020-3673 TSCA Considerations When Evaluating Exposure Assessments (PDF) provides guidance when evaluating the quality of modeling and monitoring data. OPPT RAD 3673
Draft Biotech/Algae guidance document 2016-10-01 2020-02-28 EPA 705-G-2020-3116 biotechnology Implementation of microorganism regulations under Section 5 of the Toxic Substances Control Act (TSCA) OPPT RAD 3116
Ecological Effects Test Guidelines: Aquatic Fauna Test Guidelines, 850.1085, Fish Acute Toxicity Mitigated by Humic Acid 1996-04-01 2020-02-28 EPA 712-C-96-117 Public Draft; Test Guideline; Ecological Effects The following test guideline is part of a series that has been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OPPT RAD 160
Ecological Structure Activity Relationships (ECOSAR) Predictive Model 2019-05-09 2020-02-28 EPA 705-G-2020-3650 TSCA The Ecological Structure Activity Relationships (ECOSAR) Class Program is a computerized predictive system that estimates aquatic toxicity. OPPT RAD 3650
E-FAST-Exposure and Fate Assessment Screening Tool Version 2014 2014-01-01 2020-02-28 EPA 705-G-2020-3660 TSCA Estimates consumer, general public and environmental exposures to chemicals. OPPT RAD 3660
EPA ExpoBox (A Toolbox for Exposure Assessors) 2011-10-01 2020-02-28 EPA 705-G-2020-3656 TSCA and FIFRA ExpoBox is a toolbox created to assist individuals from within government, industry, academia, and the general public with assessing exposure. OPPT RAD 3656
EPA Exposure Factors Handbook 2011-10-01 2020-02-28 EPA 705-G-2020-3657 TSCA The Exposure Factors Handbook provides information on various physiological and behavioral factors commonly used in assessing exposure to environmental chemicals. OPPT RAD 3657
EPI Suite™-Estimation Program Interface 2011-01-01 2020-02-28 EPA 705-G-2020-3659 TSCA Estimates physical / chemical properties (melting point, water solubility, etc.) and environmental fate properties (breakdown in water or air, etc.) which can indicate where a chemical will go in the environment and how long it will stay there. OPPT RAD 3659
Fate, Transport and Transformation Test Guidelines: , 835.0001, Principles and Strategies Related to Biodegradation Testing of Organic Chemicals under the Toxic Substances Control Act (TSCA) 2008-11-01 2020-02-28 EPA 712-C-08-008 TSCA This guideline is one of a series of test guidelines that have been developed by the Office of Prevention, Pesticides and Toxic Substances (OPPT), for use in the testing of pesticides and toxic substances, and the development of test data to meet the data requirements of the Agency under the Toxic Substances Control Act (TSCA) (15 U.S.C. 2601), the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) (7 U.S.C. 136, et seq.), and section 408 of the Federal Food, Drug and Cosmetic (FFDCA) (21 U.S.C. 346a). OPPT RAD 148
Final Version of the 2017 Update to the Coordinated Framework for the Regulation of Biotechnology 2017-01-01 2020-02-28 EPA 705-G-2020-3113 Biotechnology The Coordinated Framework is a sequel to the 1986 Coordinated Framework for the Regulation of Biotechnology and the 1992 Update to the Coordinated Framework OPPT RAD 3113
Formaldehyde Indoor air Model - pressed wood products (FIAM-pwp) 2019-06-01 2020-02-28 EPA 705-G-2020-3669 TSCA The Formaldehyde Indoor Air Model-pressed wood products (FIAM-pwp) user guide contains information on the equations and defaults used to estimate exposure from formaldehyde emitted from pressed wood products. FIAM is part of the IGEMS suite of models. OPPT RAD 3669
Guidance to Assist Interested Persons in Developing and Submitting Draft Risk Evaluations Under the Toxic Substances Control Act Documents 2017-06-22 2020-02-28 EPA 705-G-2020-1695 Assessing and Managing Chemicals under TSCA Guidance to Assist Interested Persons in Developing and Submitting Draft Risk Evaluations Under the Toxic Substances Control Act June OPPT RAD 1695
Guidelines for Exposure Assessment 1992-05-29 2020-02-28 EPA 705-G-2020-3655 TSCA and FIFRA The Guidelines for Exposure Assessment are intended for risk assessors in EPA, and those exposure and risk assessment consultants, contractors, or other persons who perform work under Agency contract or sponsorship. In addition, publication of these Guidelines makes information on the principles, concepts, and methods used by the Agency available to all interested members of the public. OPPT RAD 3655
Guidelines for Statistical Analysis of Occupational Exposure Data 1994-08-01 2020-02-28 EPA 705-G-2020-3678 TSCA Guidelines for Statistical Analysis of Occupational Exposure Data provides guidance for statistical analysis of worker exposure data. OPPT RAD 3678
IGEMS/CSM-Internet Geographical Exposure Modeling System/Chemical Safety Mapper 2012-04-07 2020-02-28 EPA 705-G-2020-3662 TSCA IGEMS brings together in one system several EPA environmental fate and transport models and some of the environmental data needed to run them. OPPT RAD 3662
IIOAC - Integrated Indoor-Outdoor Air Calculator 2019-08-01 2020-02-28 EPA 705-G-2020-3661 TSCA A tool based on EPA’s AERMOD for use in assessing releases to air and exposure potential for new and existing chemicals. OPPT RAD 3661
Indoor Environmental Concentrations in Buildings with Conditioned and Unconditioned Zones (IECCU) 2019-06-01 2020-02-28 EPA 705-G-2020-3667 TSCA This program serves two purposes: (1) as a general-purpose indoor exposure model in buildings with multiple zones, multiple chemicals and multiple sources and sinks, and (2) as a special-purpose concentration model for simulating the effects of sources in unconditioned zones on the indoor environmental concentrations in conditioned zones. OPPT RAD 3667
Indoor Exposure Product Testing Protocols, Version 2.0 2016-09-01 2020-02-28 EPA 705-G-2020-3685 TSCA Provides information on how to conduct product testing to inform exposures in indoor environments. OPPT RAD 3685
Interim Approaches for Assessing and Controlling Workplace Releases and Exposures to New and Existing Nanomaterials 2012-05-01 2020-02-28 EPA 705-G-2020-3682 TSCA This document provides guidance for assessing and controlling worker exposure and releases to manufactured nanomaterials. OPPT RAD 3682
Interim Guidance for Using Ready and Inherent Biodegradability Tests to Derive Input Data for Multimedia Models and Wastewater Treatment Plants (WWT) Models (9/1/2000) 2000-09-01 2020-02-28 EPA 705-G-2020-3680 TSCA This document provides interim guidance for using ready and inherent biodegradability tests to derive input data for multimedia models and wastewater treatment plant models. OPPT RAD 3680
Interim Technical Guidance for Assessing Screening Level Environmental Fate and Transport of, and General Population, Consumer, and Environmental Exposure to Nanomaterials 2010-06-17 2020-02-28 EPA 705-G-2020-3681 TSCA Technical Guidance for Assessing Screening Level Environmental Fate and Transport of, and General Population, Consumer, and Environmental Exposure to Nanomaterials provides guidance for estimating fate and transport and exposure to engineered nanomaterials. OPPT RAD 3681
Model Averaging for Dichotomous Response Benchmark Dose (MADr-BMD) Tool 2008-06-26 2020-02-28 EPA 705-G-2020-3654 TSCA The Model Averaging for Dichotomous Response Benchmark Dose (MADr-BMD) tool is a downloadable program that implements model averaging based upon dichotomous dose-response data. OPPT RAD 3654
Multi-chamber Concentration and Exposure Model (MCCEM) 2011-01-01 2020-02-28 EPA 705-G-2020-3666 TSCA Documentation within the model provide guidance on how to use the it. OPPT RAD 3666
New Chemicals Program under TSCA Chemical Categories Document 2010-08-01 2020-02-28 EPA 705-G-2020-3676 TSCA This page has the New Chemicals Program's Chemical Categories Document, which explains how EPA uses the categories, enabling both PMN submitters and EPA reviewers to benefit from the accumulated data and past decisional precedents allowing reviews to be facilitated. OPPT RAD 3676
Non-Cancer Screening Approaches for Health Effects 2010-01-01 2020-02-28 EPA 705-G-2020-3675 TSCA Provides user with a procedure of identifying health effects data for the chemical of interest from various public databases and gives insight into various chemical classes associated with health effects of concern. OPPT RAD 3675
OncoLogic™ - A Computer System to Evaluate the Carcinogenic Potential of Chemicals 2013-09-01 2020-02-28 EPA 705-G-2020-3651 TSCA The OncoLogic™ model is a predictive system that mimics the judgment of human experts by following sets of knowledge rules based on studies of how chemicals cause cancer in animals and humans. OPPT RAD 3651
Point Source Calculator Version 1.05 (PSC v1.05) 2019-06-01 2020-02-28 EPA 705-G-2020-3663 TSCA An aquatic model that OPPT uses to estimate chemical concentrations in water column, porewater, and sediment from point sources. OPPT RAD 3663
Points to Consider in the preparation of TSCA biotechnology submissions for microorganisms:  1997-06-02 2020-02-28 EPA 705-G-2020-3115 biotechnology Points to consider for microorganism submissions OPPT RAD 3115
Points to Consider When Preparing TSCA New Chemical Notifications 2017-11-07 2020-02-28 EPA 705-G-2020-1719 Reviewing New Chemicals under the Toxic Substances Control Act (TSCA) This document provides EPA scientific approaches, best practices, and other general guidance that are not binding on either EPA or any outside parties. OPPT RAD 1719
Predictive Models and Tools for Assessing Chemicals under the Toxic Substances Control Act (TSCA) 2016-06-22 2020-02-28 EPA 705-G-2020-3118 Predictive Models and Tools EPA has developed assessment methods, databases, and predictive tools to help evaluate what happens to chemicals when they are used and released to the environment and how workers, citizens, and the environment might be exposed to and affected by them. OPPT RAD 3118
Recommendations for Estimating Transport Between Environmental Compartment (Fugacity) for Existing chemicals, including HPV chemicals 2014-01-01 2020-02-28 EPA 705-G-2020-3674 TSCA Guidance on what model to use when estimating transport between environmental compartments. OPPT RAD 3674
Scenarios Document for Screening Level Exposure and Release Assessment 2000-09-01 2020-02-28 EPA 705-G-2020-3683 TSCA Scenarios document providing guidance for screening level exposure and release assessment. OPPT RAD 3683
Source Ranking Database 2003-06-01 2020-02-28 EPA 705-G-2020-3670 TSCA Documentation within the model provide guidance on how to use the it. OPPT RAD 3670
Sustainable Futures / P2 Framework Manual 2012-01-01 2020-02-28 EPA 705-G-2020-3112 Sustainable Futures Sustainable Futures / P2 Framework Manual - Introduction, Table of Contents, Sections 1-14 and Appendices A-H OPPT RAD 3112
Using Predictive Methods to Assess Hazard under TSCA 2015-09-01 2020-02-28 EPA 705-G-2020-3672 TSCA Provides information on the information each model can provide when a hazard assessment is done. Each predictive tool is designed with the goal of estimating activities of untested chemicals based on their structural similarity to chemicals with known activities. Predictive methods have a long history of use both for the industrial design and regulatory assessment of chemicals. OPPT RAD 3672
Wall Paint Exposure Model (WPEM) 2011-01-01 2020-02-28 EPA 705-G-2020-3668 TSCA The purpose of the model is to allow industry product developers and health and safety officials to more easily and accurately identify chemicals in paint formulations that may pose potential exposure problems. OPPT RAD 3668
Advanced Concepts Training Module 2019-03-01 2020-02-28 EPA 705-G-2020-2257 Toxics Release Inventory (TRI) Program The advanced concepts training assumes a basic understanding of TRI requirements. This training focuses on recent changes to requirements, advanced guidance on threshold determinations and reporting, and reporting for chemicals with special requirements. More information on electronic reporting is also included. EPA provides archived versions of slides for prior reporting years as well. OPPT TRIPD 2257
Basic Concepts Training Module 2019-03-01 2020-02-28 EPA 705-G-2020-2256 Toxics Release Inventory (TRI) Program The basic concepts training will help you determine whether your facility has triggered EPCRA Section 313 (TRI) reporting requirements for one or more chemicals. This training includes topics on reporting thresholds, reporting forms, and reporting exemptions as well as an introduction to electronic reporting. EPA provides archived versions of slides for prior reporting years as well. OPPT TRIPD 2256
Chemical Distribution Facilities Guidance Document 1999-01-01 2020-02-28 EPA 745-B-99-005 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for Chemical Distribution Facilities who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to Chemical Distribution Facilities. OPPT TRIPD 2241
Coal Mining Facilities Guidance Document 2000-02-01 2020-02-28 EPA 745-B-00-003 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for Coal Mining Facilities who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to Coal Mining Facilities. OPPT TRIPD 2242
Definition of Otherwise Use 2004-12-01 2020-02-28 EPA 705-G-2020-2258 Toxics Release Inventory (TRI) Program This document contains guidance for reporting facilities on the interpretation of the term “otherwise use” as it relates to EPCRA Section 313. This document focuses on current and revised interpretation of otherwise use. Examples of the revised interpretation of otherwise use are also included. OPPT TRIPD 2258
Electricity Generating Facilities Guidance Document 2000-02-01 2020-02-28 EPA 745-B-00-004 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for Electricity Generating Facilities who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to Electricity Generating Facilities. OPPT TRIPD 2243
EPCRA Section 313 Questions & Answers 2019 Consolidation Document 2019-04-01 2020-02-28 EPA 745-B-19-001 Toxics Release Inventory (TRI) Program The TRI Program has published the 2019 Q&As Consolidation document. This document compiles the previous Q&A guidance documents, which are now archived. OPPT TRIPD 2214
Food Processors Guidance Document 1998-09-01 2020-02-28 EPA 745-R-98-011 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for Food Processors who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to Food Processors. OPPT TRIPD 2244
Interpretations of Waste Management Activities 1999-08-01 2020-02-28 EPA 705-G-2020-2259 Toxics Release Inventory (TRI) Program This document contains guidance for reporting facilities on the interpretation of the term “waste management” as it relates to EPCRA Section 313. Facilities may also use this document to learn more about EPA’s interpretations of different waste management methods for TRI reporting purposes, including recycling, recovery for energy, treatment for destruction, and release. OPPT TRIPD 2259
Leather Tanning and Finishing Guidance Document 2000-04-01 2020-02-28 EPA 745-B-00-012 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for Leather Tanning And Finishing who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to Leather Tanning And Finishing. OPPT TRIPD 2245
Metal Mining Facilities Guidance Document 1999-01-01 2020-02-28 EPA 745-B-99-001 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for Metal Mining Facilities who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to Metal Mining Facilities. OPPT TRIPD 2246
Metal Mining Naturally Occurring Chemicals 2001-07-14 2020-02-28 EPA 705-G-2020-2247 Toxics Release Inventory (TRI) Program This page lists documents provided by EPA following National Mining Association v. U.S. Environmental Protection Agency and Barrick Goldstrike Mines, Inc. v. Whitman. Among other topics, these documents focus on TRI reporting requirements related to “naturally occurring” toxic chemicals, beneficiation of ore, intra-category manufacture, toxic chemical impurities, waste rock, and tailings. OPPT TRIPD 2247
Petroleum Terminals and Bulk Storage Facilities Guidance Document 2000-02-01 2020-02-28 EPA 745-B-00-002 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for Petroleum Terminals and Bulk Storage Facilities who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to Petroleum Terminals and Bulk Storage Facilities. OPPT TRIPD 2248
Presswood and Laminated Products Industry Guidance Document 2001-08-01 2020-02-28 EPA 260-B-01-013 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for Presswood and Laminated Products Industry who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to Presswood and Laminated Products Industry. OPPT TRIPD 2249
Printing, Publishing, and Packaging Industry Guidance Document 2000-05-01 2020-02-28 EPA 745-B-00-005 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for Printing, Publishing, and Packaging Industry who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to Printing, Publishing, and Packaging Industry. OPPT TRIPD 2250
RCRA Subtitle C TSD Facilities and Solvent Recovery Facilities Guidance Document 1999-01-01 2020-02-28 EPA 745-B-99-004 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for RCRA Subtitle C TSD Facilities And Solvent Recovery Facilities who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to RCRA Subtitle C TSD Facilities And Solvent Recovery Facilities. OPPT TRIPD 2251
Reporting Forms and Instructions Guidance 2019-01-01 2020-02-28 EPA 740-B-18-001 Toxics Release Inventory (TRI) Program The RFI contains details on how to determine if TRI reporting is required, how to fill out reporting forms (including detailed explanations of every reporting element on the form), and changes to reporting requirements (if any) for the current reporting year. TRI also provides archive versions back to Reporting Year 1988. OPPT TRIPD 2213
Rubber and Plastics Manufacturing Guidance Document 2000-05-01 2020-02-28 EPA 745-B-00-017 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for Rubber And Plastics Manufacturing who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to Rubber And Plastics Manufacturing. OPPT TRIPD 2252
Semiconductor Manufacturing Guidance Document 1999-07-01 2020-02-28 EPA 745-R-99-007 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for Semiconductor Manufacturing who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to Semiconductor Manufacturing. OPPT TRIPD 2253
Spray Applications and Electrodeposition of Organic Coatings Guidance Document 1998-12-01 2020-02-28 EPA 745-R-98-014 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for Spray Application and Electrodeposition of Organic Coatings who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to Spray Application and Electrodeposition of Organic Coatings. OPPT TRIPD 2254
Supplier Notification Requirements 1998-12-01 2020-02-28 EPA 705-G-2020-2260 Toxics Release Inventory (TRI) Program This document contains guidance for reporting facilities on supplier notification requirements as it relates to EPCRA Section 313. Facilities may use this document to learn more about who must provide notification, what notification must include, how the notification must be made, and when notification is required. OPPT TRIPD 2260
Textile Processing Industry Guidance Document 2000-05-01 2020-02-28 EPA 745-B-00-008 Toxics Release Inventory (TRI) Program This document is a step-by-step guide for Textile Processing Industry who must report to TRI. Guidance on determining your reporting requirements, recording quantities of chemicals manufactured, processed, or otherwise used, and calculating releases and other waste management activities is contained within the following sections. Companies may also use this document to consult examples of chemical management activities common to Textile Processing Industry. OPPT TRIPD 2255
TRI Guidance for Reporting and List of Toxic Chemicals within the Polychlorinated Alkanes Category 2019-03-01 2020-02-28 EPA 745-B-19-008 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Polychlorinated Alkanes Category. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2234
TRI Guidance for Reporting and List of Toxic Chemicals within the Water Dissociable Nitrate Compounds Category 2019-02-01 2020-02-28 EPA 745-B-19-007 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Nitrate Compounds. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2232
TRI Guidance for Reporting Aqueous Ammonia 2019-02-01 2020-02-28 EPA 745-B-19-002 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Aqueous Ammonia. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2222
TRI Guidance for Reporting Compounds and Mixtures 2019-02-01 2020-02-28 EPA 745-B-19-015 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Compounds and Mixtures. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2225
TRI Guidance for Reporting Hydrochloric Acid (acid aerosols including mists, vapors, gas, fog, and other airborne forms of any particle size) 2019-02-01 2020-02-28 EPA 745-B-19-017 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Hydrochloric Acid Aerosols. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2228
TRI Guidance for Reporting Lead and Lead Compounds Category 2019-02-01 2020-02-28 EPA 745-B-19-020 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Lead and Lead Compounds. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2229
TRI Guidance for Reporting Mercury and Mercury Compounds Category 2019-02-01 2020-02-28 EPA 745-B-19-014 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Mercury and Mercury Compounds Category. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2230
TRI Guidance for Reporting Pesticides and Other Persistent Bioaccumulative (PBT) Chemicals 2019-02-01 2020-02-28 EPA 745-B-19-011 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Pesticides and Other Persistent Bioaccumulative Toxic Chemicals. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2233
TRI Guidance for Reporting Polychlorinated Biphenyls (PCBs) 2019-02-01 2020-02-28 EPA 745-B-19-016 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Polychlorinated Biphenyls (PCBs) Category. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2235
TRI Guidance for Reporting Polycyclic Aromatic Compounds Category 2019-02-01 2020-02-28 EPA 745-B-19-019 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Polycyclic Aromatic Compounds. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2236
TRI Guidance for Reporting Sulfuric Acid (acid aerosols including mists, vapors, gas, fog, and other airborne forms of any particle size) 2019-02-01 2020-02-28 EPA 745-B-19-018 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Sulfuric Acid Aerosols. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2238
TRI Guidance for Reporting Toxic Chemical Categories 2019-02-01 2020-02-28 EPA 745-B-19-013 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Toxic Chemical Categories. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2239
TRI Guidance for Reporting Toxic Chemicals within the Dioxin and Dioxin-like Compounds Category 2019-03-01 2020-02-28 EPA 745-B-19-004 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Dioxin and Dioxin-like Compounds Category. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2226
TRI List of Toxic Chemicals within the Certain Glycol Ethers Category 2019-03-01 2020-02-28 EPA 745-B-19-012 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Certain Glycol Ethers Category. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2223
TRI List of Toxic Chemicals within the Chlorophenols Category 2019-02-01 2020-02-28 EPA 745-B-19-003 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Chlorophenols Category. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2224
TRI List of Toxic Chemicals within the Ethylenebisdithiocarbamic Acid, Salts and Esters Category and List of Mixtures that Contain the Individually Listed Chemicals Maneb, Metiram 2019-02-01 2020-02-28 EPA 745-B-19-005 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use EBDC Acid, Salts and Esters Category and Mixtures Containing Maneb, Metiram, Nabam, and Zineb. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2227
TRI List of Toxic Chemicals within the Nicotine and Salts Category 2019-02-01 2020-02-28 EPA 745-B-19-006 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Nicotine and Salts. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2231
TRI List of Toxic Chemicals within the Strychnine and Salts Category 2019-02-01 2020-02-28 EPA 745-B-19-009 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Strychnine and Salts. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2237
TRI List of Toxic Chemicals within the Warfarin and Salts Category 2019-02-01 2020-02-28 EPA 745-B-19-010 Toxics Release Inventory (TRI) Program This document contains information for facilities which manufacture, produce, or otherwise use Warfarin and Salts. Additional guidance on who must report, reportable quantities, and how to estimate annual releases can be found in the following sections. OPPT TRIPD 2240
Amphibian Metamorphosis Assay 2011-09-01 2020-02-28 EPA 705-G-2020-3369 Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT Amphibian Metamorphosis Assay, 890.1100, Study Profile Template. OSCP EACPD 3369
Amphibian Metamorphosis Assay 2011-10-12 2020-02-28 EPA 705-G-2020-3575 Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, data evaluation spreadsheet template, DEST Amphibian Metamorphosis Assay, 890.1100, Data Evaluation Spreadsheet Template. OSCP EACPD 3575
Androgen Receptor Binding (Rat Prostate) 2011-10-01 2020-02-28 EPA 705-G-2020-3370 Endocrine Disruptor Testing, test guideline, Androgen Receptor Binding (Rat Prostate), 890.1150, Study Profile Template, SPT Androgen Receptor Binding (Rat Prostate), 890.1150, Study Profile Template. OSCP EACPD 3370
Androgen Receptor Binding (Rat Prostate) 2011-09-20 2020-02-28 EPA 705-G-2020-3576 Endocrine Disruptor Screening Program, EDSP, Androgen Receptor Binding, data evaluation spreadsheet template, DEST Androgen Receptor Binding, 890.1150, Data Evaluation Spreadsheet Template. OSCP EACPD 3576
Aromatase (Human Recombinant) 2011-07-01 2020-02-28 EPA 705-G-2020-3371 Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT Aromatase (Human Recombinant), 890.1200, Study Profile Template OSCP EACPD 3371
Aromatase (Human Recombinant) 2011-09-30 2020-02-28 EPA 705-G-2020-3577 Endocrine Disruptor Screening Program, EDSP, Aromatase, data evaluation spreadsheet template, DEST Aromatase (Human Recombinant), 890.1200, Data Evaluation Spreadsheet Template OSCP EACPD 3577
Corrections and Clarifications on Technical Aspects of the Endocrine Disruptor Screening Program Tier 1 Assays (OCSPP test guideline series 890) 2011-03-04 2020-02-28 EPA 705-G-2020-3586 Endocrine Disruptor Screening Program; EDSP; EDSP Tier 1 Assays; Corrections, Clarifications In response to questions raised by Test Order recipients and others, e.g., Endocrine Policy Form, CropLife America, the Agency provided a detailed guidance document correcting and clarifying technical aspects of the conduct of Tier 1 assays for the EDSP. (37 p) OSCP EACPD 3586
Endocrine Disruptor Screening Program 1998-08-11 2020-02-28 EPA 705-G-2020-3563 Endocrine Disruptor Screening Program; EDSP; Policy; EDSTAC Policy Notice; EPA's Initial outline of the Endocrine Disruptor Screening Program (EDSP) OSCP EACPD 3563
Endocrine Disruptor Screening Program (EDSP); Announcing the Availability of the Tier 1 Screening Battery and Related Test Guidelines 2009-10-21 2020-02-28 EPA 705-G-2020-3623 Endocrine Disruptor Screening Program, EDSP, Tier 1, test guidelines Notice of Availability; EPA is announcing the availability of the Endocrine Disruptor Screening Program (EDSP) Tier 1 battery of assays and availability of test guidelines (protocols) for conducting the assays included in the battery. The EDSP was established under section 408(p) of the Federal Food, Drug, and Cosmetic Act (FFDCA), which directed EPA “to develop a screening program. . .to determine whether certain substances may have an effect in humans that is similar to an effect produced by a naturally occurring estrogen, or such other endocrine effect as the Administrator may designate.” Coordinated by EPA, several in vitro and in vivo screening assays were developed, standardized, and validated to identify the potential of a chemical substance to interact with the estrogen, androgen or thyroid (E, A, or T) hormonal systems. Test chemicals that were thought to be potentially interactive as well as non-interactive with the E, A, or T hormonal systems were used to evaluate feasibility of the protocols, relevance of endpoints and reliability of results within and among independent contract laboratories. Subsequent independent peer review of individual assays helped to clarify the strengths and limitations of each assay and define their modes of action involving the E, A, or T hormonal systems within the context of the EDSP Tier 1 battery. EPA submitted a proposed battery of assays to the Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel (FIFRA SAP) for external peer review in March 2008. Based on the SAP recommendation, which found the proposed battery adequate to begin screening chemicals to detect the potential for interaction with the E, A, or T hormonal systems,  OSCP EACPD 3623
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1100, Amphibian Metamorphosis (Frog) 2009-10-01 2020-02-28 EPA 740-C-09-002 Endocrine Disruption Testing; 890.1100; test guideline; Amphibian Metamorphosis (Frog) This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 375
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1150, Androgen Receptor Binding (Rat Prostate Cytosol) 2009-10-01 2020-02-28 EPA 740-C-09-003 Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines, 890.1150, Androgen Receptor Binding (Rat Prostate Cytosol) This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 376
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1200, Aromatase (Human Recombinant) 2009-10-01 2020-02-28 EPA 740-C-09-004 Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines; 890.1200; Aromatase (Human Recombinant) This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 377
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1250, Estrogen Receptor Binding (Rat Uterine Cytosol) 2009-10-01 2020-02-28 EPA 740-C-09-005 Endocrine Disruption Testing;  EDSP Tier 1 Test Guidelines; 890.1250; Estrogen Receptor Binding (Rat Uterine Cytosol) This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 378
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1300, Estrogen Receptor Transcriptional Activation (Human Cell Line (HeLa-9903)) 2009-10-01 2020-02-28 EPA 740-C-09-006 Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines; 890.1300; Estrogen Receptor Transcriptional Activation (Human Cell Line (HeLa-9903)); ERTA This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 379
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1350, Fish Short-term Reproduction 2009-10-01 2020-02-28 EPA 740-C-09-007 Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines: 890.1350:  Fish Short-term Reproduction This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 380
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1400, Hershberger (Rat) 2009-10-01 2020-02-28 EPA 740-C-09-008 Endocrine Disruption Testing;  EDSP Tier 1 Test Guidelines; 890.1400; Hershberger (Rat) This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 381
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1450, Female Pubertal (Rat) 2009-10-01 2020-02-28 EPA 740-C-09-009 Endocrine Disruption Testing;  EDSP Tier 1 Test Guidelines; 890.1450; Female Pubertal (Rat) This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 382
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1500, Male Pubertal (Rat) 2009-10-01 2020-02-28 EPA 740-C-09-012 Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines; 890.1500; Male Pubertal (Rat) This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 383
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1550, Steroidogenesis (Human Cell Line - H295R) 2009-10-01 2020-02-28 EPA 740-C-09-011 Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines; 890.1550; Steroidogenesis (Human Cell Line - H295R) This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 384
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 1 Test Guidelines, 890.1600, Uterotrophic (Rat) 2009-10-01 2020-02-28 EPA 740-C-09-010 Endocrine Disruption Testing; EDSP Tier 1 Test Guidelines; 890.1600; Uterotrophic (Rat) The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 385
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 2 Test Guidelines, 890.2100, Avian Two-Generation Toxicity Test in the Japanese Quail 2015-08-01 2020-02-28 EPA 740-C-15-003 Endocrine Disruption Testing; EDSP Tier 2 Test Guidelines; 890.2100, Avian Two-Generation Toxicity Test in the Japanese Quail; JQTT The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 386
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 2 Test Guidelines, 890.2200, Medaka Extended One Generation Reproduction Test 2015-08-01 2020-02-28 EPA 740-C-15-002 Endocrine Disruption Testing; EDSP Tier 2 Test Guidelines; 890.2200; Medaka Extended One Generation Reproduction Test The following test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 387
Endocrine Disruptor Screening Program Test Guidelines: EDSP Tier 2 Test Guidelines, 890.2300, Larval Amphibian Growth and Development Assay 2015-08-01 2020-02-28 EPA 740-C-15-001 Endocrine Disruption Testing; EDSP Tier 2 Test Guidelines; 890.2300; Larval Amphibian Growth and Development Assay; LAGDA This test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review. OSCP EACPD 388
Endocrine Disruptor Screening Program Test Guidelines: Three Tier 2 Non-Mammalian Tests 2015-08-25 2020-02-28 EPA 705-G-2020-3621 Endocrine Disruptor Screening Program, EDSP, Tier 2, test guidelines, Larval Amphibian Growth and Development Assay,  LAGDA, Medaka Extended One-generation Reproduction Test, MEOGRT, Avian Two-generation Toxicity Test in the Japanese Quail, JQTT Notice of Availability; EPA is announcing the availability of three Office of Chemical Safety and Pollution Prevention (OCSPP) final test guidelines: Medaka Extended One-generation Reproduction Test (MEOGRT), OCSPP Test Guideline 890.2200; Larval Amphibian Growth and Development Assay (LAGDA), OCSPP Test Guideline 890.2300; and Avian Two-generation Toxicity Test in the Japanese Quail (JQTT), OCSPP Test Guideline 890.2100. These test guidelines are part of a series of test guidelines established by OCSPP for use in testing pesticides and chemical substances. OSCP EACPD 3621
Endocrine Disruptor Screening Program Tier 1 Assays: Considerations for Use in Human Health and Ecological Risk Assessments 2013-06-01 2020-02-28 EPA 705-G-2020-3553 Endocrine Disruptor Screening Program, EDSP, Tier 1, testing Guidance for the conduct of Tier 1 screening assays for endocrine disruption effects. OSCP EACPD 3553
Endocrine Disruptor Screening Program Universe of Chemicals 2012-11-01 2020-02-28 EPA 705-G-2020-3588 Endocrine Disruptor Screening Program; EDSP; EDSP Universe of Chemicals Guidance on EDSP Universe of Chemicals for potential endocrine disruptor screening and testing OSCP EACPD 3588
Endocrine Disruptor Screening Program Universe of Chemicals and General Validation Principles 2012-11-01 2020-02-28 EPA 705-G-2020-3569 Endocrine Disruptor Screening Program; EDSP; EDSP Universe of Chemicals; EDSP General Validation Principles U.S. Environmental Protection Agency Endocrine Disruptor Screening Program Universe of Chemicals and General Validation Principles. A Guidance document jointly developed by the Office of Chemical Safety & Pollution Prevention, the Office of Water and the Office of Research and Development.  OSCP EACPD 3569
Endocrine Disruptor Screening Program Weight-of-Evidence: Evaluating Results of EDSP Tier 1 Screening to Identify the Need for Tier 2 Testing 2011-09-14 2020-02-28 EPA 705-G-2020-3587 Weight-of-Evidence, WoE, EDSP, Tier 1 Screening This guidance document provides basic principles and criteria for using a weight-of-evidence (WoE) approach for evaluation and interpretation of EDSP Tier 1 screening, which includes Tier 1 assay results and other information to identify candidate chemicals for Tier 2 testing. OSCP EACPD 3587
Endocrine Disruptor Screening Program: Use of High Throughput Assays and Computational Tools 2015-06-15 2020-02-28 EPA 705-G-2020-3573 Endocrine Disruptor Screening Program; EDSP; EDSP Policy; High Throughput Assays; HT; Computational Toxicology; Comp Tox Policy Notice; This document describes how EPA is planning to incorporate an alternative scientific approach to screen chemicals for their ability to interact with the endocrine system. This will improve the Agency's ability to fulfill its statutory mandate to screen pesticide chemicals and other substances for their ability to cause adverse effects by their interaction with the endocrine system. The approach incorporates validated high throughput assays and a computational model and, based on current research, can serve as an alternative for some of the current assays in the Endocrine Disruptor Screening Program (EDSP) Tier 1 battery. EPA has partial screening results for over 1800 chemicals that have been evaluated using high throughput assays and a computational model for the estrogen receptor pathway. In the future, EPA anticipates that additional alternative methods will be available for EDSP chemical screening based on further advancements of high throughput assays and computational models for other endocrine pathways. Use of these alternative methods will accelerate the pace of screening, decrease costs, and reduce animal testing. In addition, this approach advances the goal of providing sensitive, specific, quantitative, and efficient screening using alternative test methods to some assays in the Tier 1 battery to protect human health and the environment. OSCP EACPD 3573
Endocrine Disruptor Screening Program: Weight-of-Evidence Guidance Document; Availability 2011-09-28 2020-02-28 EPA 705-G-2020-3622 Endocrine Disruptor Screening Program; EDSP; Policy; EDSP List 1; Weight-of-Evidence Notice of Availability; EPA's Endocrine Disruptor Screening Program (EDSP) is announcing the availability of a final guidance document titled, “Weight-of-Evidence: Evaluating Results of EDSP Tier 1 Screening to Identify the Need for Tier 2 Testing.” This weight-of-evidence (WoE) guidance document was revised based on public and peer review comments and existing peer-reviewed EPA guidelines. This guidance document provides basic principles and criteria for application of a WoE approach to evaluate results from the battery of Tier 1 screening assays along with other scientific and technical information relevant to Tier 1 screening to determine whether or not a chemical has the potential to interact with the estrogen, androgen, or thyroid (E, A, or T) hormonal pathways of the endocrine system. The combined results and information will also be used to identify which tests and information may be needed for Tier 2 testing. OSCP EACPD 3622
Endocrine Disruptor Screening Program; Final Policies and Procedures for Screening Safe Drinking Water Act Chemicals 2013-06-14 2020-02-28 EPA 705-G-2020-3571 Endocrine Disruptor Screening Program; EDSP;  Safe Drinking Water Act; SDWA; Policy  Policy Notice. This document describes EPA's final policies and procedures for requiring Tier 1 screening under the Endocrine Disruptor Screening Program (EDSP) of chemicals for which EPA may issue EDSP test orders pursuant to section 1457 of the Safe Drinking Water Act (SDWA) and section 408(p) of the Federal Food, Drug, and Cosmetic Act (FFDCA). Section 408(p) of the FFDCA directed EPA to develop a chemical screening program using appropriate validated test systems and other scientifically relevant information (OSRI) to determine whether certain chemicals may have hormonal effects. These final policies and procedures supplement the EDSP policies and procedures that were published in the Federal Register on April 15, 2009. OSCP EACPD 3571
Endocrine Disruptor Screening Program; Final Second List of Chemicals and Substances for Tier 1 Screening 2013-06-14 2020-02-28 EPA 705-G-2020-3570 Endocrine Disruptor Screening Program; EDSP; EDSP Policy; EDSP List 2; Chemical Selection Policy Notice; Description of Final EDSP List 2. This document announces the final second list of 109 chemicals identified for Tier 1 screening under the Endocrine Disruptor Screening Program (EDSP). The EDSP is established under section 408(p) of the Federal Food, Drug, and Cosmetic Act (FFDCA), which requires EPA to develop a chemical screening program using appropriate validated test systems and other scientifically relevant information to determine whether certain substances may have hormonal effects. The second group of chemicals to be tested consists of chemicals that section 408(p) of the FFDCA  requires be screened, i.e., pesticide active ingredients and chemicals used as pesticide inert ingredients (also known as other ingredients) and section 1457 of the 1996 amendment to the SDWA.  OSCP EACPD 3570
Endocrine Disruptor Screening Program; Policies and Procedures for Initial Screening 2009-04-15 2020-02-28 EPA 705-G-2020-3574 Endocrine Disruptor Screening Program; EDSP; Policy; Screening Policy Notice; This document describes the policies and procedures EPA generally intends to adopt for initial screening of chemicals under the Endocrine Disruptor Screening Program (EDSP). The EDSP is established under section 408(p) of the Federal Food, Drug, and Cosmetic Act (FFDCA), which requires endocrine screening of all pesticide chemicals and was established in response to growing scientific evidence that humans, domestic animals, and fish and wildlife species have exhibited adverse health consequences from exposure to environmental chemicals that interact with their endocrine systems. OSCP EACPD 3574
Endocrine Disruptor Screening Program; Proposed Statement of Policy 1998-12-28 2020-02-28 EPA 705-G-2020-3564 Endocrine Disruptor Screening Program; EDSP; Policy; EDSTAC Policy Notice; Further additional details of the Endocrine Disruptor Screening Program (EDSP) OSCP EACPD 3564
Estrogen Receptor Binding 2011-10-01 2020-02-28 EPA 705-G-2020-3372 Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT Estrogen Receptor Binding, 890.1250, Study Profile Template OSCP EACPD 3372
Estrogen Receptor Binding 2011-09-17 2020-02-28 EPA 705-G-2020-3578 Endocrine Disruptor Screening Program, EDSP, Estrogen Receptor Binding, data evaluation spreadsheet template, DEST Estrogen Receptor Binding, 890.1250, Data Evaluation Spreadsheet Template OSCP EACPD 3578
Estrogen Receptor Transcriptional Activation (Human Cell Line HeLa-9903) 2011-08-01 2020-02-28 EPA 705-G-2020-3373 Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT Estrogen Receptor Transcriptional Activation (Human Cell Line HeLa-9903), 890.1300, Study Profile Template OSCP EACPD 3373
Estrogen Receptor Transcriptional Activation (Human Cell Line HeLa-9903) 2011-09-15 2020-02-28 EPA 705-G-2020-3579 Endocrine Disruptor Screening Program, EDSP, Estrogen Transcriptional Activation (Human Cell Line HeLa-9903), data evaluation spreadsheet template, DEST Estrogen Receptor Transcriptional Activation (Human Cell Line HeLa-9903), 890.1300, Data Evaluation Spreadsheet Template OSCP EACPD 3579
Female Pubertal (Rat) 2011-08-01 2020-02-28 EPA 705-G-2020-3376 Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT Female Pubertal (Rat), 890.1450, Study Profile Template OSCP EACPD 3376
Female Pubertal (Rat) 2011-09-07 2020-02-28 EPA 705-G-2020-3582 Endocrine Disruptor Screening Program, EDSP, Female Pubertal (Rat), data evaluation spreadsheet template, DEST Aromatase (Human Recombinant), 890.1450, Data Evaluation Spreadsheet Template OSCP EACPD 3582
Final Second List of Chemicals for Tier 1 Screening 2014-06-26 2020-02-28 EPA 705-G-2020-3572 Endocrine Disruptor Screening Program; EDSP; Policy; Final EDSP List 2; Chemical Selection; Modification Modification of Final EDSP List 2 noting removal of 2 chemicals. A revised list is provided. On May 22, 2014, EPA removed hydrazine and hydrochlorofluorocarbon (HCFC-22) from the Second List of Chemicals for Screening to allow for further consideration of their physical/chemical properties and/or occurrence in regards to whether these substances are appropriate candidates for testing in the EDSP under Safe Drinking Water Act authority at this time. The U.S. Court of Appeals for the Third Circuit granted EPA’s motion for voluntary partial vacatur and remand regarding these two chemicals. OSCP EACPD 3572
Fish Short-Term Reproduction 2011-10-01 2020-02-28 EPA 705-G-2020-3374 Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT Fish Short-Term Reproduction 890.1350, Study Profile Template OSCP EACPD 3374
Fish Short-Term Reproduction 2011-09-09 2020-02-28 EPA 705-G-2020-3580 Endocrine Disruptor Screening Program, EDSP, Fish short-term reproduction, data evaluation spreadsheet template, DEST Fish Short-Term Reproduction, 890.1350, Data Evaluation Spreadsheet Template OSCP EACPD 3580
Hershberger (Rat) 2011-10-01 2020-02-28 EPA 705-G-2020-3375 Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT Hershberger, 890.1400, Study Profile Template OSCP EACPD 3375
Hershberger (Rat) 2011-09-07 2020-02-28 EPA 705-G-2020-3581 Endocrine Disruptor Screening Program, EDSP, Hershberger (Rat), data evaluation spreadsheet template, DEST Hershberger, 890.1400, Data Evaluation Spreadsheet Template OSCP EACPD 3581
Male Pubertal (Rat) 2011-08-01 2020-02-28 EPA 705-G-2020-3377 Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT Male Pubertal (Rat), 890.1500, Study Profile Template. OSCP EACPD 3377
Male Pubertal (Rat) 2011-09-07 2020-02-28 EPA 705-G-2020-3583 Endocrine Disruptor Screening Program, EDSP, Male Pubertal (Rat), data evaluation spreadsheet template, DEST Male Pubertal (Rat), 890.1500, Data Evaluation Spreadsheet Template. OSCP EACPD 3583
Steroidogenesis (Human Cell Line – H295R) 2011-07-01 2020-02-28 EPA 705-G-2020-3378 Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT Steroidogenesis (Human Cell Line - H295R), 890.1550, Study Profile Template OSCP EACPD 3378
Steroidogenesis (Human Cell Line – H295R) 2011-09-03 2020-02-28 EPA 705-G-2020-3584 Endocrine Disruptor Screening Program, EDSP, Steroidogenesis (Human Cell Line - H295R), data evaluation spreadsheet template, DEST Steroidogenesis (Human Cell Line - H295R) 890.1550, Data Evaluation Spreadsheet Template OSCP EACPD 3584
Uterotrophic (Rat) 2011-09-01 2020-02-28 EPA 705-G-2020-3379 Endocrine Disruptor Testing, test guideline, AMA, Amphibian Metamorphosis Assay, study profile template, SPT Uterotrophic (Rat), 890.1600, Study Profile Template OSCP EACPD 3379
Uterotrophic (Rat) 2011-09-07 2020-02-28 EPA 705-G-2020-3585 Endocrine Disruptor Screening Program, EDSP, Uterotrophic (Rat), data evaluation spreadsheet template, DEST Uterotrophic (Rat), 890.1600, Data Evaluation Spreadsheet Template OSCP EACPD 3585
Label Guidance for Antimicrobial Pesticides Used for Poultry House Disinfection 1980-01-17 2020-06-26 EPA 705-G-2020-2342 FIFRA, Antimicrobial The purpose of this guidance is to outline the use directions for antimicrobial pesticides used in poultry houses. OPP AD 2342
875.2300 Indoor Surface Residue Dissipation 1998-02-10 2020-06-26 EPA 705-G-2020-2366 FIFRA, Pesticides, Antimicrobial This document explains indoor surface residue test guidelines. OPP AD 2366
875.2700 Product Use Information (Post Application) 1998-02-10 2020-06-26 EPA 705-G-2020-2367 FIFRA, Pesticides, Antimicrobial This document explains the guidelines for product use information. OPP AD 2367
Label Guidance for Antimicrobial Pesticides on Hard, Non-Porous Surfaces 1979-12-02 2020-06-26 EPA 705-G-2020-2379 FIFRA, Antimicrobial This document provides information on products used on hard non-porous surfaces. OPP AD 2379
Guidance for Reregistration of Pesticide Products Containing Chlorinated Isocyanurates as the Active Ingredient 1992-09-01 2020-06-26 EPA 705-G-2020-2388 FIFRA, Antimicrobial This gives guidance for products containing chlorinated isocyanurates. OPP AD 2388
Label Guidance for Antimicrobial Pesticides Used for Sanitation of Food Contact Surfaces 1979-12-02 2020-06-26 EPA 705-G-2020-2581 FIFRA, Antimicrobial This document gives information on sanitizing food contact surfaces OPP AD 2581
Crosswalk Table for Non-Public Health Guidelines 2007-05-23 2020-06-26 EPA 705-G-2020-2599 FIFRA, Antimicrobial Determination of non-public guidelines for organisms, archived page but still good OPP AD 2599
Guidance for Testing and Labeling Claims against Pandemic 2009 H1N1 Influenza A Virus (formerly called Swine Flu) 2017-07-21 2020-06-26 EPA 705-G-2020-2603 FIFRA, Antimicrobial This document gives information on claims about 2009 pandemic flu. OPP AD 2603
Response to questions concerning existing C. diff claims (vegetative form) on antimicrobial product labels 2008-09-22 2020-06-26 EPA 705-G-2020-2605 FIFRA, Antimicrobial This document is a response to questions about C. diff claims OPP AD 2605
Barrier Products Clarification Document--Guidance for what is needed for an Agency barrier determination 2007-03-01 2020-06-26 EPA 705-G-2020-2606 FIFRA, Antimicrobial This document provides information on what is considered a barrier OPP AD 2606
Draft Interim Guidance for Non-Residual Sanitizers on Hard, Inanimate Food Contact Surfaces Using Pre-Saturated Towelettes 2001-04-12 2020-06-26 EPA 705-G-2020-2613 FIFRA, Antimicrobial This protocol can be used to conduct efficacy testing to support a pre-saturated towelette registration for use on food contact surfaces.   OPP AD 2613
BISM JWOD & Skilkraft Letter 2004-07-26 2020-06-26 EPA 705-G-2020-2614 FIFRA, Antimicrobial This letter explains the use of logos, the website is archived OPP AD 2614
Consumer Specialty Products Association (CSPA) Fruit Graphic Letter 2002-11-13 2020-06-26 EPA 705-G-2020-2615 FIFRA, Antimicrobial This letter addressed to CSPA provides Guidance regarding the use of graphics depicting fruit on antimicrobial labels. OPP AD 2615
SC Johnson Biofilms Letter 2004-07-21 2020-06-26 EPA 705-G-2020-2616 FIFRA, Antimicrobial This letter provides guidance on biofilm claims for products intended for use in the residential settings. OPP AD 2616
Antimicrobial Science Policies: Disinfectant technical Science Section (DIS/TSS) 2006-05-02 2020-06-26 EPA 705-G-2020-2625 FIFRA, Antimicrobial These documents provide a historical summary of current efficacy related requirements and/or policy for antimicrobial pesticide products, claims, and use patterns. OPP AD 2625
Subdivision G 1982-11-01 2020-06-26 EPA 705-G-2020-2631 FIFRA, Antimicrobial This subdivision of the pesticide registration guidelines concerns the effectiveness of pesticide products. These are efficacy of product guidelines. Primarily HED OPP AD 2631
Clarification of Net Contents Declarations for Antimicrobial Wipe Products 2009-02-04 2020-06-26 EPA 705-G-2020-3507 FIFRA; Pesticides; Antimicrobial; This document describes the net contents for wipe products, the website is archived. OPP AD 3507
CSPA Germs Letter 2005-01-05 2020-06-26 EPA 705-G-2020-3508 FIFRA; Pesticides; Antimicrobial; This letter (addressed to the Consumer Specialty Products Association - CSPA) provides guidance on the use of the term "germs" on antimicrobial labeling. Superseded by 1302 OPP AD 3508
Certification Statement for Design for the Environment Logo for Pesticide Products 2007-03-01 2020-06-26 EPA 705-G-2020-3511 FIFRA; Pesticides; Antimicrobial; This document explains the certification process for designed for the environment products OPP AD 3511
Guidance for the Efficacy Evaluation of Products with Sporicidal Claims Against 2014-06-01 2020-06-26 EPA 705-G-2020-3515 FIFRA; Pesticides; Antimicrobial; This product reviews the evaluations for sporicidal claims. OPP AD 3515
Guidelines for Dental Issues 1999-03-31 2020-06-26 EPA 705-G-2020-3516 FIFRA; Pesticides; Antimicrobial; This document describes examples of recent inquiries of antimicrobial dental uses, the website is archived. OPP AD 3516
NSF Logo Letter 2004-07-01 2020-06-26 EPA 705-G-2020-3533 FIFRA; Pesticides; Antimicrobial; Letter describing the NSF logo that can be used on pesticide labels. Remove OPP AD 3533
Timber Treatment Technologies TimberSil Products 2008-05-14 2020-06-26 EPA 705-G-2020-3539 FIFRA; Pesticides; Antimicrobial; This letter is in response to a request for a barrier determination for TimberSil wood products the website is archived. OPP AD 3539
Wood Preservative Organic Memorandum Letter 2007-07-02 2020-06-26 EPA 705-G-2020-3541 FIFRA; Pesticides; Antimicrobial; Memo explaining the use of the term organic with respect to pesticide products the website is archived OPP AD 3541
Standard Evaluation Procedure (SEP) for Chemistry and Acute Toxicity Science Advisory Council (CATSAC) 2019-11-27 2020-06-26 EPA 705-G-2020-3693 Pesticide Registration, FIFRA, Acute Toxicity The SEP generally describes the evaluation process for the determination of pesticide products claiming to be identical or substantially similar for the purposes of relying upon previously submitted product chemistry and/or acute toxicity data, or for bridging acute toxicity data. OPP AD 3693
Statement Regarding Respiratory Protection Shortages and Reduced Availability of Respirator Fit Testing Related to Pesticide Uses Covered by the Agricultural Worker Protection Standard during the COVID-19 Public Health Emergency 2020-06-01 2020-06-15 EPA 705-G-2020-3699 Pesticides, FIFRA, worker protection The EPA has developed this document with the goal of continuing to protect the health of pesticide handlers while acknowledging the challenges that handler employers and pesticide handlers may face with respect to personal protective equipment (PPE) OPP FEAD 3699
Instructions for Reporting: 2020 TSCA Chemical Data Reporting 2020-06-26 2020-06-26 EPA 705-G-2020-3694 Chemical Data Reporting This document, which pertains to EPA CDR reporting during 2020, updates guidance issued for reporting in 2016 to incorporate instructions relevant to 2020 reporting. It provides detailed information and examples about reporting under the CDR rule. OPPT CCD 3694
Fact Sheet: Reporting after Changes to Company Ownership or Legal Identity 2020-06-26 2020-06-26 EPA 705-G-2020-3695 Chemical Data Reporting This fact sheet provides information for persons who may be subject to the Chemical Data Reporting (CDR) rule about issues related to changes to company ownership or legal identity which may affect reporting for the 2020 reporting period. OPPT CCD 3695
Fact Sheet: Imported Articles 2020-06-26 2020-06-26 EPA 705-G-2020-3696 Chemical Data Reporting This fact sheet provides information and sample reporting scenarios on the reporting exemption for the import of a chemical substance as part of an article, for purposes of the Chemical Data Reporting (CDR) rule and updated for the 2020 CDR reporting period. OPPT CCD 3696
Fact Sheet: Importers 2020-06-26 2020-06-26 EPA 705-G-2020-3697 Chemical Data Reporting This fact sheet provides information and sample reporting scenarios on existing Chemical Data Reporting (CDR) regulations to persons who could be considered “importers” for purposes of the CDR rule, updated for the 2020 CDR reporting period. OPPT CCD 3697
Fact Sheet:  Reporting Thresholds for 2020 2020-06-26 2020-06-26 EPA 705-G-2020-3698 Chemical Data Reporting This fact sheet provides information for persons who may be subject to the Chemical Data Reporting (CDR) rule about regulatory reporting thresholds that are applicable to the 2020 reporting period. OPPT CCD 3698
Toxics Release Inventory: Federal Facility Reporting Information 2020-02-01 2020-06-26 EPA 740-B-19-038 Toxics Release Inventory; Federal Facilities This document provides helpful information unique to federal facilities reporting to TRI. OPPT TRID 3688
Toxics Release Inventory: Form R and Form A Certification Statement Reporting Codes and Instructions for Reporting Metals 2020-02-01 2020-06-26 EPA 740-B-19-039 Toxics Release Inventory This document assists industry by summarizing reporting codes and specific instructions for reporting metals for TRI Reporting purposes. OPPT TRID 3689
Estimating Releases and Waste Treatment Efficiencies for the Toxic Chemical Release Inventory Form 1987-12-01 2020-06-26 EPA 560488002 Waste treatment; Air pollution control; Waste water; Concentration (Composition); Sources; Toxic substances; Water pollution control; Liquid wastes; Solid wastes; The document provides an overview of methods for estimating releases of chemicals into the environment for TRI facilities and Community Right-to-Know Act of 1986. OPPT TRID 3690
Section 313 Emergency Planning and Community Right to Know Act Estimating Releases for Mineral Acid Discharges Using pH Measurements 1991-06-01 2020-06-26 EPA 740-R-91-003 Toxics Release Inventory The document provides estimates for estimating certain releases of certain mineral acid discharges. OPPT TRID 3691
Releases During Cleaning of Equipment 1988-07-27 2020-06-26 EPA 705-G-2020-3692 Toxics Release Inventory The document provides an overview of methods for estimating releases of chemicals into the environment for TRI related to certain cleaning activities. OPPT TRID 3692
An Example of How to Manage PCB-Containing Materials in School Buildings 2018-11-15 2020-06-26 EPA 705-G-2020-3703 PCBs A flowchart to walk owners of school buildings through the EPA guidance on PCBs in caulk and other building materials. OPPT NPCD 3703
Standardized Efficacy Study Report and Efficacy Study Summary 2017-05-24 2020-06-26 EPA 705-G-2020-3704 FIFRA, Pesticides, Antimicrobial The study report form contains all of the required elements of a study report as found in 40 CFR part 160, and meets the requirements of PR Notice 2011-3. The Efficacy Study Summary provides a form to create a summary of the important information and variables that are presented in detail in the final report. The summary may be inserted into the study report form. OPP AD 3704
June 10 , 1994 letter to Latham & Watkins re: "FDA Exemption" under TSCA 1994-06-10 2020-06-26 EPA 705-G-2020-3705 TSCA and FFDCA Jurisdiction; FDA; process wastes and effluents Letter outlining EPA's position on TSCA jurisdictional issues regarding process wastes and effluents from pharmaceutical manufacturing OPPT CCD 3705
March 30, 1994 letter to Sidley & Austin re: "TSCA/FFDCA Jurisdiction" 1994-03-30 2020-06-26 EPA 705-G-2020-3706 TSCA and FFDCA Jurisdiction; FDA Letter outlining EPA's position on TSCA and FFDCA jurisdictional issues OPPT CCD 3706
Test Method for Efficacy of Antimicrobial Agents to Reduce Foodborne Pathogenic Bacteria in Processing Waters for Fruit and Vegetables

2008-06-01

2020-06-26 EPA 705-G-2020-3707 FIFRA, pesticides This test method is used to determine If antimicrobial agents effectively reduce populations of foodborne pathogenic bacteria in fruit and vegetable processing waters. OPP AD 3707
Revised Temporary Amendment to Pesticide Registration (PR) Notice 98-10 - Notice to Manufacturers, Producers, Formulators and Registrants of Pesticides Products 2020-05-11 2020-06-26 EPA 705-G-2020-3701 FIFRA, pesticides, disinfectants The temporary amendment to PRN 98-10, signed May 11, 2020, allows registrants to notify EPA of certain formulation and manufacturing facility changes and immediately release the product for sale without waiting for EPA approval. EPA has taken this action in order to address reports of shortages of active ingredients used in surface disinfectants on EPA’s List N: Disinfectants for Use Against SARS-CoV-2, the virus that causes COVID-19, and to address shortages of food-contact surface sanitizer products used on equipment for food manufacturing and food preparation. OPP AD 3701
Expedited Review of Emerging Viral Pathogens Claim Submissions 2020-03-09 2020-06-26

EPA 705-G-2020-3702

FIFRA, pesticides, disinfectants EPA is expediting the review of emerging viral pathogen claims for EPA registered disinfectants that do not require review of new efficacy data. EPA is currently making every effort to expedite the review and make a regulatory decision for the submissions discussed in this document by at least one to two months faster than the normal PRIA timeframe, depending on the submission. OPP AD 3702
Guidance on Satisfying the Annual Pesticide Safety Training Requirement under the Agricultural Worker Protection Standard during the COVID-19 Emergency 2020-06-18 2020-06-26 EPA 705-G-2020-3700 FIFRA, pesticides, worker protection This temporary guidance addresses pesticide safety training of farmworkers and pesticide handlers in agriculture as required by the Agricultural Worker Protection Standard (WPS) (40 CFR 170). EPA is clarifying that pesticide safety training may be presented remotely, provided all of the WPS training requirements are met. OPP FEAD 3700
Fish Bioconcentration Data Requirement: Guidance for Selection of Number of Treatment Concentration 2020-07-18 2020-07-29 EPA 705-G-2020-3708 Pesticide data requirement, Testing Guidance Clarify EPA recommendations for the number of treatment concentrations needed to result in acceptable fish bioconcentration factor (BCF) studies for pesticide registration (supplements OCSPP Test Guideline 850.1730).​​​​ OPP EFED 3708
Electrostatic Spray Applications / List N 2020-07-07 2020-07-29 EPA 705-G-2020-3709 FIFRA, Antimicrobials This guidance outlines an expedited review process for adding directions for use for application using electrostatic spray for products intended for use against SARS-CoV-2, the cause of COVID-19 OPP AD 3709
Sample Form U for 2020 Chemical Data Reporting Submissions 2020-05-25 2020-07-29 EPA 705-G-2020-3710 CDR; Chemical Data Reporting; Form U Following are example printouts of the Form U from e-CDRweb, the CDR electronic reporting tool, used to make 2020 Chemical Data Reporting (CDR) submissions. The primary form printouts are associated with manufacturer reporting, including importer and co-manufacturer reporting. The secondary form printouts are associated with the secondary portion of a joint report and are completed by the secondary or tertiary submitter OPPT CCD 3710
TSCA Chemical Data Reporting Fact Sheet: Reporting Thresholds for 2020 2020-05-25 2020-07-29 EPA 705-G-2020-3711 CDR; Chemical Data Reporting; Reporting Thresholds This fact sheet provides information for persons who may be subject to the Chemical Data Reporting (CDR) rule about regulatory reporting thresholds that are applicable to the 2020 reporting period. For 2020, manufacturers must consider production volume from 2016 – 2019 as well as the effect of certain actions under the Toxic Substances Control Act (TSCA) on certain reporting thresholds when determining whether they need to report. OPPT CCD 3711
2020 TSCA Chemical Data Reporting Fact Sheet: Chemical Substances that are the Subject of Certain TSCA Actions 2020-05-25 2020-07-29 EPA 705-G-2020-3712 CDR; Chemical Data Reporting; TSCA Actions This fact sheet provides information for people who may be subject to the Chemical Data Reporting (CDR) rule on how their requirements for reporting for 2020 may be affected when chemical substances are the subject of certain actions under the Toxic Substances Control Act (TSCA). Manufacturers must consider the effect of certain TSCA actions on reporting when determining whether they need to report based on production volume thresholds and their eligibility for some of the exemptions which reduce or eliminate reporting requirements. New for 2020 is the addition of TSCA section 4 orders to the list of certain TSCA actions, an updated small manufacturer definition, and a new small government definition. OPPT CCD 3712
2020 TSCA Chemical Data Reporting Fact Sheet: Co-Manufactured Chemicals 2020-05-25 2020-07-29 EPA 705-G-2020-3713 CDR; Chemical Data Reporting; Co-manufacture; Producing Company; Contracting Company This fact sheet provides information on existing Chemical Data Reporting (CDR) regulations for persons who are involved in co-manufacturing of chemical substances that may be subject to the CDR rule. New procedures for reporting co-manufactured chemical substances are in use beginning with the 2020 CDR submission period. OPPT CCD 3713
TSCA Chemical Data Reporting Fact Sheet: Non-Isolated Intermediates 2020-05-25 2020-07-29 EPA 705-G-2020-3714 CDR; Chemical Data Reporting; Byproducts; Intermediates This fact sheet provides information on the reporting exemption applicable to non-isolated intermediate chemical substances for purposes of the Chemical Data Reporting (CDR) rule (40 CFR 711). OPPT CCD 3714
TSCA Chemical Data Reporting Fact Sheet: Kraft Pulp and Paper Process 2020-05-25 2020-07-29 EPA 705-G-2020-3715 CDR; Chemical Data Reporting; Kraft pulping; Byproducts This fact sheet provides information on Chemical Data Reporting (CDR) rule requirements related to the reporting of chemical substances manufactured during the Kraft pulp and paper process. OPPT CCD 3715
TSCA Chemical Data Reporting Fact Sheet: Byproducts Reporting for the Printed Circuit Board Industry 2020-06-30 2020-07-29 EPA 705-G-2020-3716 CDR; Chemical Data Reporting This fact sheet provides information on existing Chemical Data Reporting (CDR) rule requirements related to byproducts reporting by persons who manufacture printed circuit boards and may be subject to CDR. OPPT CCD 3716
2020 Chemical Data Reporting Frequent Questions 2020-07-14 2020-07-29 EPA 705-G-2020-3717 CDR; Chemical Data Reporting; Frequent Questions; FAQ These Frequent Questions (FQs) are intended to clarify the reporting requirements for Chemical Data Reporting for the 2020 reporting period. OPPT CCD 3717;
CSPP CDX Registration Guide 2020-04-30 2020-07-29 EPA 705-G-2020-3718 CDR; CDX; Registration Guide The Central Data Exchange (CDX) is a system used for many electronic environmental data submissions to the U.S. Environmental Protection Agency (EPA). CDX allows users submitting data to the EPA to register for the specific program of interest. This Registration Guide describes the registration process and information requirements associated with Submissions for the Chemical Safety and Pesticide Programs (CSPP). OPPT CCD 3718
Guidance regarding the Certification of Pesticide Applicators during the COVID-19 Public Health Emergency 2020-07-27 2020-07-29 EPA 705-G-2020-3719 FIFRA, Certification of Pesticide Applicators To help states, tribes, and federal certifying authorities meet both the needs of applicators and the requirements of the Certification of Pesticide Applicators (CPA) rule (40 CFR Part 171) during this COVID-19 PHE, EPA has developed this guidance based on certifying authorities’ input. ​​​​​ OPP FEAD 3719
Guidance for Waiving Acute Dermal Toxicity Tests for Pesticide Technical Chemicals & Supporting Retrospective Analysis 2020-12-31 2021-01-19 EPA 705-G-2020-3722 FIFRA, pesticides, data requirements This guidance document follows upon the final dermal waiver guidance published in November 2016 for pesticide formulations. This document expands the potential for data waivers for acute dermal studies to single active ingredient technical chemicals (technical chemicals) used to formulate end user products. OPP AD 2723
Compliance Guide for Imported Articles Containing Surface Coatings Subject to the Long-Chain PFAS Significant New Use Rule 2021-01-19 2021-01-19 RIN 2070-ZA23 Chemicals under the Toxic Substances Control Act (TSCA); PFAS ​Outlines which imported articles are covered by the agency’s July 2020 final Significant New Use Rule (SNUR) that prohibits companies from manufacturing, importing, processing, or using certain long-chain PFAS without prior EPA review and approval. OPPT CCD 3727